Abstract:
:In keeping with the stated goal of providing the surgical pathologist with tools to recognize abnormalities of the gastrointestinal (GI) tract due to drugs (AGIDS), in part II of this review we embark in a more organ-based description of AGIDS. Adequate space is given to the numerous adverse gastrointestinal effects of nonsteroidal anti-inflammatory drugs. Pill esophagitis, esophagitis dissecans, proton pump inhibitors' effects, diaphragm disease, and the recently described effects of drugs such as olmesartan, mycophenolate, and of compounds such as yttrium-90 are highlighted among several others. The inclusion of drug effects in the differential diagnosis of "conventional" diseases (such as gastric antral vascular ectasia, graft-versus-host disease, ischemic colitis, acute colitis, collagenous enteritis, inflammatory bowel disease) is underscored to avoid sometimes significant diagnostic pitfalls. We reiterate the message of the necessary collaboration between pathologist and clinician in the recognition of these entities to provide the best patient care.
journal_name
Int J Surg Patholjournal_title
International journal of surgical pathologyauthors
De Petris G,Caldero SG,Chen L,Xiao SY,Dhungel BM,Spizcka AJ,Lam-Himlin Ddoi
10.1177/1066896913502230subject
Has Abstractpub_date
2014-05-01 00:00:00pages
202-11issue
3eissn
1066-8969issn
1940-2465pii
1066896913502230journal_volume
22pub_type
杂志文章,评审abstract::A 45-year-old woman presented with a short history of abdominal distension and features of intestinal obstruction. Computed tomography examination of the abdomen revealed a solid and cystic mass in the region of the left ovary, but spread within the abdomen was also noted. The ovarian tumor was removed, and an omentec...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690100900411
更新日期:2001-10-01 00:00:00
abstract::Male breast carcinomas (MBCs) are rare neoplasms that account for 0.1% of all male cancers. Still, there are 2000 new cases of MCB diagnosed annually in the United States. Because of its rarity, data regarding the etiology, risk factors, diagnosis, management, and prognosis of MBC are limited. MBC shares some similari...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896916675953
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:Renal cell carcinomas (RCCs) in children and adolescents are much rarer than in adults. In this age group, Xp11.2 translocation RCCs were the most common subtype of pediatric RCCs. Information regarding the clinical behavior of pediatric RCCs remains controversial because of their relatively rare incidence. ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,meta分析
doi:10.1177/1066896910375565
更新日期:2010-12-01 00:00:00
abstract::We report the case of a well-differentiated chondrosarcoma of the proximal humerus in a 60-year-old man that featured a prominent component of granular cells, the granules being shown by electron microscopy to be lysosomal. Although secondary granular cell changes have been described in a large variety of tumor types,...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690601400211
更新日期:2006-04-01 00:00:00
abstract::Hodgkin lymphoma (HL) associated with Warthin tumor (WT) is extremely rare, accounting for only 3 cases of classical HLs. Here, we report for the first time the occurrence of a nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) involving the lymphoid stroma of a WT of the parotid gland. Pathogenesis of WT is cont...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896915582263
更新日期:2015-08-01 00:00:00
abstract::St. Gallen 2005 expert consensus guideline modified its criteria for the risk category of breast cancer (BC) patients by integrating a combination of lymph nodes with metastasis (positive lymph nodes [PLNs]) and HER-2/neu status of tumor. Recently, some studies have shown that lymph node ratio (LNR), defined as the ra...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896912451323
更新日期:2012-12-01 00:00:00
abstract::The aim of this study is to analyze all the cases of benign fibro-osseous lesions treated at School and Hospital of Stomatology, Wuhan University, to compare the results obtained in this study with those previously documented by other authors. The 127 cases diagnosed as a fibro-osseous lesion were retrieved, and infor...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896908318744
更新日期:2009-04-01 00:00:00
abstract::Peribiliary cysts, otherwise known as cystic dilatation of the peribiliary glands, are uncommon, and are usually discovered incidentally at autopsy, or in explants following liver transplantation. Preoperative diagnosis is often difficult owing to their asymptomatic nature and small size. Exclusion of a premalignant o...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690501300416
更新日期:2005-10-01 00:00:00
abstract::Infiltrating ductal carcinoma (IDC) occurs frequently in patients with lobular carcinoma in-situ (LCIS). LCIS is not thought to be the direct precursor of the invasive component. The authors analyzed 15 cases of coexisting LCIS and IDC and found ductal carcinoma in situ (DCIS) in 12. The DCIS and IDC were of similar g...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690100900206
更新日期:2001-04-01 00:00:00
abstract::Primary carcinoid tumor of the skin (PCTS) is an uncommon indolent neoplasm, with 10 cases described in the literature. The tumors affect patients in the sixth to ninth decades of life (mean = 66.3 years) with an equal gender distribution and predilection for the head and trunk. They present as slowly enlarging nodule...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896913516672
更新日期:2014-04-01 00:00:00
abstract::Atypical adenomatous hyperplasia (AAH) of the prostate is a microscopic proliferation of small acini that may be mistaken for adenocarcinoma. Although some data suggest that AAH is associated with adenocarcinoma arising in the transition zone, the clinical significance of this lesion is uncertain. Therefore we studied...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690501300207
更新日期:2005-04-01 00:00:00
abstract::Because of its rarity, pathologic and clinical features of Hodgkin lymphoma-like posttransplant lymphoproliferative disorder (HL-like PTLD) are not well understood, and it is unclear whether its biological behavior is more closely related to classical Hodgkin disease or to monomorphic B-cell PTLD. The authors compared...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896909338597
更新日期:2010-08-01 00:00:00
abstract::We report our experience with Chromogenic in Situ Hybridization (CISH) for the evaluation of HER2 amplification on 55 cases of formalin-fixed, paraffin-embedded invasive breast carcinomas of different histology. All the results were corrected for chromosome 17 aneusomy and compared with immunohistochemistry (IHC); a s...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690501300406
更新日期:2005-10-01 00:00:00
abstract::Mixed squamous and glandular papilloma (mixed papilloma) of the lung has been reported in fewer than 25 cases in the English literature. Although it is known as a benign tumor, malignant transformation has been reported. Papillary cystic carcinoma is characterized by papillary and cystic growth patterns and has been r...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920908330
更新日期:2020-09-01 00:00:00
abstract::We review the clinical, pathologic, and molecular genetic features of 3 splenic T-cell-rich B-cell lymphomas and discuss their differential diagnosis. All patients presented with symptomatic splenomegaly and underwent diagnostic/therapeutic splenectomy. Microscopically, the spleen in all cases showed a micronodular pr...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690401200105
更新日期:2004-01-01 00:00:00
abstract::The rare reports of mucinous variant of follicular carcinoma of the thyroid gland have not provided enough evidence to support the recognition of these tumors as a distinct clinicopathologic entity or to understand their etiopathogenesis. We report the fourth case of mucinous variant of follicular carcinoma displaying...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896915617026
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Epithelioid hemangioendothelioma (EHE) is an uncommon malignant endothelial neoplasm that most commonly arises in soft tissue, bone, lung, and liver. Crohn's disease (CD) is an inflammatory bowel disease of unknown etiology that is frequently associated with complications including strictures, fistulas/fissu...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896918801527
更新日期:2019-06-01 00:00:00
abstract::We report a case of metaplastic columnar epithelium in the mid-esophagus in a patient with history of caustic ingestion. A cardiac-type gastric phenotype, with early signs of intestinalization, was confirmed by immunohistochemistry studies (MUC5AC, MUC6, SOX2, and CDX2). Nonmetaplastic mucosa had histologic evidence o...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916672332
更新日期:2017-05-01 00:00:00
abstract::Renal cell carcinoma (RCC) in children and young adults is rare and pathologically problematic. RCC can be either hereditary or sporadic and has a guarded prognosis because appropriate management has not been established. A case of RCC in an 11-year-old is reported. The clinical presentation was a right abdominal mass...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896907304994
更新日期:2008-01-01 00:00:00
abstract::Diaphragm disease of small intestine usually presents with nonspecific clinical features. Radiological investigations often fail to differentiate it from small intestinal tumors and inflammatory bowel disease. It is therefore diagnosed on final histology after surgical resection. We hereby report an interesting case o...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896914563392
更新日期:2015-06-01 00:00:00
abstract:AIMS:Diffuse large B-cell lymphomas (DLBCL) can be divided into different subgroups (germinal center B-cell-like [GCB] and non-GCB) according to their gene expression profiles. Immunohistochemistry has been proposed as a surrogate for identifying these subgroups, but data about its efficacy in providing prognostic info...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896909345596
更新日期:2011-08-01 00:00:00
abstract::Tissue contaminants in anatomical pathology are not uncommon. While issues related to the presence of extraneous tissue on glass slides are often easily resolved, this is not always the case and several factors may contribute to diagnostic difficulty. Because of this, familiarity with the different steps involved in h...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920913110
更新日期:2020-10-01 00:00:00
abstract:CONTEXT.:Follicular cholecystitis (FC) is a poorly characterized entity. OBJECTIVE.:To determine its frequency/clinicopathologic associations. DESIGN.:A total of 2550 cholecystectomy specimens were examined. Two hundred three of these were consecutive routine cholecystectomies submitted entirely for microscopic exami...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920924079
更新日期:2020-12-01 00:00:00
abstract::Lanthanum carbonate (LC) is a new type of phosphate adsorbent used to treat patients with hyperphosphatemia caused by chronic kidney diseases. Recent studies have pointed out that lanthanum deposition can be found in the cytoplasm of histiocytes in the gastroduodenal mucosa of these patients. On the other hand, it is ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917718623
更新日期:2017-12-01 00:00:00
abstract::Intralymphatic histiocytosis (ILH) is a peculiar pathological process characterized by the collections of benign histiocytes in dilated lymph vessels. Although the majority of ILH patients present clinically with various forms of cutaneous manifestation, rare extracutaneous incidences have been reported in the literat...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916688307
更新日期:2017-06-01 00:00:00
abstract::Ectopic adrenal cortical neoplasms are extremely rare, and only a few have involved the CNS. We report the first case of an intramedullary oncocytic adrenal cortical neoplasm of the spinal cord with immunohistochemical (IMHC) confirmation. A 27-year-old man presented with progressive lower extremity weakness, spastic ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690401200309
更新日期:2004-07-01 00:00:00
abstract::Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a rare tumor-like lesion with unclear pathogenesis. Collision lesions of CAPNONs with neoplasms are occasionally reported. In this article, we report the first case of collision lesions between CAPNON and rheumatoid nodules (RNs) in a patient with systemic lupus er...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920941939
更新日期:2020-07-15 00:00:00
abstract::Clear cell chondrosarcoma (CCCS) is a rare variant of conventional chondrosarcoma with low-grade malignant features that may be confused radiographically and histologically with chondroblastoma. We report a case of a 50-year-old female who presented with 6 months of left hip pain. Initial radiographs demonstrated an o...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896918776092
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Phyllodes tumors (PTs) of the breast are rare biphasic neoplasms and are classified as benign, borderline, or malignant. Many biological markers have been studied to discriminate between different grades of PTs. IMP3 is a member of the insulin-like growth factor II mRNA binding protein (IMP) family and is ex...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915603119
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:To assess the pathologic characteristics and prognostic significance of periprostatic lymph node (LN) metastasis of prostate cancer. The latter was performed by comparing biochemical recurrence (BCR)-free survival in cases of periprostatic LN metastasis versus matched patients showing pelvic LN metastasis. M...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896913482729
更新日期:2013-08-01 00:00:00