A Practical Approach to Investigating Cross-Contaminants in the Anatomical Pathology Laboratory.

Abstract:

:Tissue contaminants in anatomical pathology are not uncommon. While issues related to the presence of extraneous tissue on glass slides are often easily resolved, this is not always the case and several factors may contribute to diagnostic difficulty. Because of this, familiarity with the different steps involved in handling specimens in the anatomical pathology laboratory is essential when troubleshooting possible cross-contaminants. Most commonly, the specimen constituting the source of cross-contamination is handled before the actual contaminated case; however, this is not always so. In this article, we review the steps involved in processing pathology specimens as they pertain to cross-contamination; share an approach covering how to troubleshoot and prevent tissue contaminants in a systematic and practical manner; present some examples from our own experiences; and compare our experience to what is reported in the literature. The information included in this article will be of use to all members of the anatomical pathology team including medical laboratory technologists, laboratory managers and supervisors, pathologist assistants, trainees in pathology, and pathologists.

journal_name

Int J Surg Pathol

authors

Hodgson AJ,Shang YM,Boulianne P,Downes MR,Hwang D,Slodkowska E

doi

10.1177/1066896920913110

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

700-710

issue

7

eissn

1066-8969

issn

1940-2465

journal_volume

28

pub_type

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