Metaplastic thymoma: report of an unusual thymic epithelial neoplasm arising in the wall of a thymic cyst.

Abstract:

:In this report, a case of metaplastic thymoma arising in a thymic cyst wall is discussed. The patient was a 61-year-old male whose chief complaint was sweating and chest pain. Imaging study revealed a mediastinal mass with right hemithoracic extension. He underwent surgical resection of the mass and remnants of the thymus. Histologic studies showed a primary thymic neoplasm with a biphasic histologic pattern composed of 2 distinct epithelial and stromal components arising in a thymic cyst wall. Immunohistochemically, the epithelial component was cytokeratin positive and focally reactive for EMA. Marked expression of EMA and vimentin was seen in spindle cells. Metaplastic thymoma is an extremely rare variant of primary thymic epithelial neoplasms with only a few cases reported in the literature.

journal_name

Int J Surg Pathol

authors

Poorabdollah M,Mehdizadeh E,Mohammadi F,Sabeti S

doi

10.1177/1066896908315754

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

51-4

issue

1

eissn

1066-8969

issn

1940-2465

pii

1066896908315754

journal_volume

17

pub_type

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