Immunohistochemical analysis of expressions of RB1, CDK4, HSP90, cPLA2G4A, and CHMP2B is helpful in distinction between myxofibrosarcoma and myxoid liposarcoma.

abstract：BACKGROUND:The rate of incidental prostate adenocarcinoma (PCa) detection in radical cystoprostatectomy (RCP) varies widely, ranging from 15% to 54%. Such variability may be explained by institutional differences in prostate grossing protocols. Either partial or complete submission of the prostate gland in RCP may resu...

journal_title：International journal of surgical pathology

authors： Filter ER,Gabril MY,Gomez JA,Wang PZT,Chin JL,Izawa J,Moussa M

更新日期：2017-08-01 00:00:00

abstract：:Combined lung cancers containing both small cell and non-small cell carcinoma elements are uncommon but well recognized. Lung tumors with neuroendocrine differentiation form a group of histologically distinct tumors with differing clinical behavior ranging from low-grade tumors with good prognosis (typical carcinoid) ...

journal_title：International journal of surgical pathology

authors： Owens CL,Fraire AE

更新日期：2011-04-01 00:00:00

abstract：:Studies on the expression of beta-catenin (beta-ct) in gastric carcinoma have provided conflicting results, and the role played by beta-ct mutations in gastric carcinogenesis remains unclear. In an attempt to clarify the aforementioned issues we undertook the retrospective study of 157 gastric carcinomas by using immu...

journal_title：International journal of surgical pathology

authors： Nabais S,Machado JC,Lopes C,Seruca R,Carneiro F,Sobrinho-Simões M

更新日期：2003-01-01 00:00:00

abstract：:Lynch syndrome is a hereditary disease with germline mutation in a DNA mismatch repair gene, most often presenting with colorectal and/or endometrial carcinomas; however, the spectrum of Lynch syndrome-associated tumors is expanding. In this article, we report a case of a primary peritoneal epithelioid mesothelioma th...

journal_title：International journal of surgical pathology

authors： Lu Y,Milchgrub S,Khatri G,Gopal P

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Protein kinase C βII promotes melanogenesis and affects proliferation of melanocytic cells but is frequently absent or decreased in melanoma cells in vitro. OBJECTIVE:To investigate PKC-βII expression and spatial distribution within a lesion in various benign and malignant melanocytic proliferations. METHO...

journal_title：International journal of surgical pathology

authors： Krasagakis K,Tsentelierou E,Chlouverakis G,Stathopoulos EN

更新日期：2017-09-01 00:00:00

abstract：:Circulating tumor cells are rare in peripheral blood smears. We report the case of a patient with circulating breast carcinoma cells resembling circulating myeloid blasts and provide a brief review of the literature. Peripheral blood smears and a bone marrow aspirate were examined morphologically and by flow cytometry...

journal_title：International journal of surgical pathology

authors： Rowan DJ,Logunova V,van Tuinen P,Olteanu H,Peterson JF

更新日期：2017-02-01 00:00:00

abstract：:Lymphoplasmacyte-rich meningioma (LPRM) is an extremely rare variant of meningioma, and a small percentage of LPRM may be associated with IgG4-related disease. To date, the coexistence of 2 rare meningioma variants consisting of LPRM and angiomatous meningioma within one neoplasm has not been reported in the literatur...

journal_title：International journal of surgical pathology

authors： Son HJ,Yu IK,Kim SM

更新日期：2018-02-01 00:00:00

abstract：:We present an unusual association of mediastinal germ cell tumor containing seminoma and angiosarcoma components and splenic histiocytic sarcoma. A 15-year-old boy presented with chest pain. Histopathologically, an anterior mediastinal mass contained typical seminoma, immature teratoma, embryonal carcinoma, angiosarco...

journal_title：International journal of surgical pathology

authors： Song SY,Ko YH,Ahn G

更新日期：2005-07-01 00:00:00

abstract：:The aim of this study was to investigate protein expression of adenomatous polyposis coli (APC) in primary and metastatic serous ovarian carcinoma. The expression of beta-catenin and E-cadherin was additionally analyzed. One hundred and thirteen primary (n = 56) and metastatic (n = 57) lesions were immunohistochemical...

journal_title：International journal of surgical pathology

authors： Karbova E,Davidson B,Metodiev K,Tropé CG,Nesland JM

更新日期：2002-07-01 00:00:00

abstract：:To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...

journal_title：International journal of surgical pathology

authors： Rao Q,Chen JY,Wang JD,Ma HH,Zhou HB,Lu ZF,Zhou XJ

更新日期：2011-04-01 00:00:00

abstract：:The aim of this study was to investigate the role of UbcH10 expression in the differential diagnosis of benign, hyperplastic, and malignant endometrial tissues and also the relationship of UbcH10 with the clinicopathologic parameters of malignant cases. A tissue microarray was performed for 81 endometrial curettage bi...

journal_title：International journal of surgical pathology

authors： Kefeli M,Yildiz L,Celik H,Tosun M,Karagoz F

更新日期：2012-08-01 00:00:00

abstract：:Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases at the ...

journal_title：International journal of surgical pathology

authors： Toll AD,Mitchell D,Yeo CJ,Hruban RH,Witkiewicz AK

更新日期：2011-12-01 00:00:00

abstract：:A 37-year-old woman was found to have multiple peritoneal nodules, including on the uterine serosa, at Cesarean section. Histology showed yellow crystalline material surrounded by histiocytes and occasional multinucleate giant cells. Further enquiry revealed that the patient underwent a cholecystectomy for a perforate...

journal_title：International journal of surgical pathology

authors： McVeigh G,McComiskey M,McCluggage WG

更新日期：2012-02-01 00:00:00

abstract：:Adenocarcinomas and noninvasive intraepithelial neoplasms (either polypoid or flat) are the most common gallbladder tumors; however, neuroendocrine neoplasms (NENs) can also occur. The majority of NENs are represented by neuroendocrine carcinomas (NECs), while neuroendocrine tumors (NETs) are extremely rare in this lo...

journal_title：International journal of surgical pathology

authors： Kővári B,Turkevi-Nagy S,Lauwers GY,Jiang K

更新日期：2021-01-09 00:00:00

abstract：:Cystic squamous cell carcinomas (SCCs) of the jaws, including carcinoma cuniculatum, are rare, slow growing, and relentlessly invasive. The aim of this article is to present 12 cases, 4 of which were designated as carcinoma cuniculatum on the basis of deeply endophytic, anastomosing channels of cystic stratified squam...

journal_title：International journal of surgical pathology

authors： Barrett AW,Garg M,Armstrong D,Bisase BS,Newman L,Norris PM,Shelley M,Tighe JV,Hyde NC,Chaston NJ,Gulati A

更新日期：2020-09-01 00:00:00

abstract：:Primary carcinoid tumor of the skin (PCTS) is an uncommon indolent neoplasm, with 10 cases described in the literature. The tumors affect patients in the sixth to ninth decades of life (mean = 66.3 years) with an equal gender distribution and predilection for the head and trunk. They present as slowly enlarging nodule...

journal_title：International journal of surgical pathology

authors： Jedrych J,Pulitzer M

更新日期：2014-04-01 00:00:00

abstract：:We report our experience with Chromogenic in Situ Hybridization (CISH) for the evaluation of HER2 amplification on 55 cases of formalin-fixed, paraffin-embedded invasive breast carcinomas of different histology. All the results were corrected for chromosome 17 aneusomy and compared with immunohistochemistry (IHC); a s...

journal_title：International journal of surgical pathology

authors： Li-Ning-T E,Ronchetti R,Torres-Cabala C,Merino MJ

更新日期：2005-10-01 00:00:00

abstract：:A 16-year-old boy presented with a tumor located in fourth ventricle, which showed histological features of an ependymoma replete with perivascular pseudorosettes and true ependymal rosettes. Interestingly, many of the tumor cells exhibited abundant cytoplasm stuffed with a grayish brown pigment. Histochemical stains ...

journal_title：International journal of surgical pathology

authors： Malhotra A,Rao S,Santhoshkumar R,Muralidharan N,Mitra S,Shetty S

更新日期：2021-02-01 00:00:00

abstract：:Fibroadenoma and phyllodes tumors of the breast exhibit a continuum of pathologic features. We examined phyllodes tumors initially called fibroadenoma for features that may accurately classify the tumor as phyllodes tumor on the first biopsy specimen. The phyllodes tumors initially called fibroadenoma for features tha...

journal_title：International journal of surgical pathology

authors： Yohe S,Yeh IT

更新日期：2008-04-01 00:00:00

abstract：:In this study, we examined aberrant methylation of the E-cadherin, estrogen receptor, RB1 , p16, p15, p14, and MGMT genes by the methylation-specific polymerase chain reaction method in 101 gastric carcinomas. Hypermethylation was detected in E-cadherin, estrogen receptor, RB1, p16, p14, p15, and MGMT at the rates of ...

journal_title：International journal of surgical pathology

authors： Zhao YF,Zhang YG,Tian XX,Juan Du,Jie Zheng

更新日期：2007-07-01 00:00:00

abstract：:Juvenile xanthogranuloma (JXG) is a benign histiocytic disorder usually affecting the head and trunk region of a child. The isolated occurrence of JXG in the penile shaft of a young adult is hitherto unreported. This lesion is amenable to surgical resection although systemic and/or internal visceral involvement can oc...

journal_title：International journal of surgical pathology

authors： Majumder R,Biswas D,Mishra TS,Mitra S

更新日期：2020-09-01 00:00:00

abstract：:Warthin tumor is the second most common salivary gland neoplasm. It occurs more commonly in males than in females. Malignant transformation in Warthin tumor is a rare but well-recognized phenomenon; however, the development or presentation of lymphoma in a Warthin tumor is rare. An 80-year-old man presented with painl...

journal_title：International journal of surgical pathology

authors： Jawad H,McCarthy P,O'Leary G,Heffron CC

更新日期：2018-05-01 00:00:00

abstract：:Clear cell chondrosarcoma (CCCS) is a rare variant of conventional chondrosarcoma with low-grade malignant features that may be confused radiographically and histologically with chondroblastoma. We report a case of a 50-year-old female who presented with 6 months of left hip pain. Initial radiographs demonstrated an o...

journal_title：International journal of surgical pathology

authors： Kiefer RM,Wojcik J,Cooper K,Weber KL,Sebro R

更新日期：2018-12-01 00:00:00

abstract：:Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described entity that, despite significant pleomorphism, carries a good prognosis. We briefly describe this tumor and its principal differential diagnoses. Recognition of SCPFTs, including the clinical context in which they arise, is important to avoid...

journal_title：International journal of surgical pathology

authors： Foot O,Hallin M,Bagué S,Jones RL,Thway K

更新日期：2020-12-01 00:00:00

abstract：:The rare reports of mucinous variant of follicular carcinoma of the thyroid gland have not provided enough evidence to support the recognition of these tumors as a distinct clinicopathologic entity or to understand their etiopathogenesis. We report the fourth case of mucinous variant of follicular carcinoma displaying...

journal_title：International journal of surgical pathology

authors： Squillaci S,Pitino A,Spairani C,Ferrari M,Carlon E,Cosimi MF

更新日期：2016-04-01 00:00:00

abstract：:Rosai-Dorfman disease (RDD; sinus histiocytosis with massive lymphoadenopathy) is a rare, usually nodal self-limited disease. Sometimes nodal disease is coupled with extranodal localizations, in which case the disease can follow a protracted clinical course characterized by remissions and relapses and, exceptionally, ...

journal_title：International journal of surgical pathology

authors： Di Tommaso L,Rahal D,Bossi P,Roncalli M

更新日期：2010-12-01 00:00:00

abstract：:Esophageal ectopic sebaceous glands are very rare lesions. A series of 5 cases in a single report has been the maximum number described in the English literature to date. We conducted a clinicopathologic study of 8 cases of esophageal ectopic sebaceous glands. The median patient age at the time of diagnosis was 60 yea...

journal_title：International journal of surgical pathology

authors： Hashimoto H,Horiuchi H,Miura S,Takayanagi S,Gunji T,Morikawa T

更新日期：2020-08-26 00:00:00

abstract：:Atypical adenomatous hyperplasia (AAH) of the prostate is a microscopic proliferation of small acini that may be mistaken for adenocarcinoma. Although some data suggest that AAH is associated with adenocarcinoma arising in the transition zone, the clinical significance of this lesion is uncertain. Therefore we studied...

journal_title：International journal of surgical pathology

authors： Lopez-Beltran A,Qian J,Montironi R,Luque RJ,Bostwick DG

更新日期：2005-04-01 00:00:00

abstract：:We present the first documented case of hemangioblastoma located in the left colon. A 75-year-old woman undergoing adjuvant chemotherapy for breast cancer experienced rectal bleeding. Colonoscopy revealed a roundish mass covered with normal mucosa in the sigmoid colon. Endoscopic ultrasound showed an isoechoic lesion ...

journal_title：International journal of surgical pathology

authors： Casadei Gardini A,Pieri F,Fusaroli P,Oboldi D,Passardi A,Monti M,Rosetti P,Calpona S,Valgiusti M,Ragazzini A,Amadori D,Frassineti GL

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Epithelioid hemangioendothelioma (EHE) is an uncommon malignant endothelial neoplasm that most commonly arises in soft tissue, bone, lung, and liver. Crohn's disease (CD) is an inflammatory bowel disease of unknown etiology that is frequently associated with complications including strictures, fistulas/fissu...

journal_title：International journal of surgical pathology

authors： Spasic S,Brcic I,Freire R,Garcia-Buitrago MT,Rosenberg AE

更新日期：2019-06-01 00:00:00