Aberrant methylation of multiple genes in gastric carcinomas.

abstract：:A 46-year-old man presented with nonproductive cough and lower limb swelling. Chest radiograph showed a left lower lobe lung mass and multiple subpleural nodules. Other investigations revealed that he had nephrotic syndrome. Core biopsies of the left lower lobe lung mass showed features of inflammatory pseudotumor wit...

journal_title：International journal of surgical pathology

authors： Govender D,Jackson C,Chetty D

更新日期：2021-02-01 00:00:00

abstract：AIMS. GIARDIA:is sometimes missed by the pathologist, and we sought to determine how often this occurs at our institution-a large tertiary care center with a subspecialty gastrointestinal pathology service and what certain clinical and histologic clues can be used to flag cases with a higher likelihood of infection, ta...

journal_title：International journal of surgical pathology

authors： Shen MJ,Voltaggio L,Robertson S

更新日期：2020-08-10 00:00:00

abstract：:In keeping with the stated goal of providing the surgical pathologist with tools to recognize abnormalities of the gastrointestinal (GI) tract due to drugs (AGIDS), in part II of this review we embark in a more organ-based description of AGIDS. Adequate space is given to the numerous adverse gastrointestinal effects o...

journal_title：International journal of surgical pathology

authors： De Petris G,Caldero SG,Chen L,Xiao SY,Dhungel BM,Spizcka AJ,Lam-Himlin D

更新日期：2014-05-01 00:00:00

abstract：:To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...

journal_title：International journal of surgical pathology

authors： Rao Q,Chen JY,Wang JD,Ma HH,Zhou HB,Lu ZF,Zhou XJ

更新日期：2011-04-01 00:00:00

abstract：:In this study, the pathogenesis of clear cell change in colorectal epithelial lesions was studied. A total of 4 cases of clear cell change (1 hyperplasic polyp and 3 adenomas) were characterized using histochemistry, immunohistochemistry, and electron microscopy. All lesions developed in the left colon. In all, 1 aden...

journal_title：International journal of surgical pathology

authors： Eloy C,Lopes JM,Faria G,Moreira H,Brandão A,Silva T,Carneiro F

更新日期：2009-12-01 00:00:00

abstract：:Renal cell carcinoma (RCC) in children and young adults is rare and pathologically problematic. RCC can be either hereditary or sporadic and has a guarded prognosis because appropriate management has not been established. A case of RCC in an 11-year-old is reported. The clinical presentation was a right abdominal mass...

journal_title：International journal of surgical pathology

authors： Winarti NW,Argani P,De Marzo AM,Hicks J,Mulyadi K

更新日期：2008-01-01 00:00:00

abstract：:The authors describe a case of multifocal perivascular epithelioid cell tumor (PEComa) arising in the pelvis of a 39-year-old woman affected by tuberous sclerosis. The tumor presented in the form of multiple fascicular, focally cystic nodules involving the uterine corpus, both ovaries, and the omentum. Microscopically...

journal_title：International journal of surgical pathology

authors： Froio E,Piana S,Cavazza A,Valli R,Abrate M,Gardini G

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Epithelioid hemangioendothelioma (EHE) is an uncommon malignant endothelial neoplasm that most commonly arises in soft tissue, bone, lung, and liver. Crohn's disease (CD) is an inflammatory bowel disease of unknown etiology that is frequently associated with complications including strictures, fistulas/fissu...

journal_title：International journal of surgical pathology

authors： Spasic S,Brcic I,Freire R,Garcia-Buitrago MT,Rosenberg AE

更新日期：2019-06-01 00:00:00

abstract：:Mammary-type myofibroblastoma (MFB) is a benign spindle cell tumor of the breast and soft tissue characterized by 13q14 alterations leading to loss of Rb-1 protein expression, a feature shared among spindle cell lipoma and cellular angiofibroma. In this article, we present a novel case of MFB arising in the left breas...

journal_title：International journal of surgical pathology

authors： Strait AM,Linos K,Tafe LJ,Muller KE

更新日期：2020-08-05 00:00:00

abstract：:Verruciform xanthoma is a rare benign verrucopapillary lesion that develops in the oral mucosa and genital skin. Its development in the esophagus is extremely rare, with only 5 reported cases. We present 2 cases of verruciform xanthoma of the esophagus. Case 1 involved a 91-year-old woman, who had hypertension and chr...

journal_title：International journal of surgical pathology

authors： Noguchi H,Kitazono I,Hamada K,Tanaka T,Tasaki T,Shirahama H,Yamamoto Y,Tanimoto A

更新日期：2020-05-01 00:00:00

abstract：:Circulating tumor cells are rare in peripheral blood smears. We report the case of a patient with circulating breast carcinoma cells resembling circulating myeloid blasts and provide a brief review of the literature. Peripheral blood smears and a bone marrow aspirate were examined morphologically and by flow cytometry...

journal_title：International journal of surgical pathology

authors： Rowan DJ,Logunova V,van Tuinen P,Olteanu H,Peterson JF

更新日期：2017-02-01 00:00:00

abstract：:Background. In this single-institution study, we applied the current (eighth edition) American Joint Committee on Cancer pathologic staging criteria to 64 low-grade mucinous neoplasms of the appendix (LAMNs), examined their histopathologic features, and studied the patients' clinical outcomes. Design. Sixty-four LAMNs...

journal_title：International journal of surgical pathology

authors： Wong M,Barrows B,Gangi A,Kim S,Mertens RB,Dhall D

更新日期：2020-05-01 00:00:00

abstract：:Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a rare tumor-like lesion with unclear pathogenesis. Collision lesions of CAPNONs with neoplasms are occasionally reported. In this article, we report the first case of collision lesions between CAPNON and rheumatoid nodules (RNs) in a patient with systemic lupus er...

journal_title：International journal of surgical pathology

authors： Lu JQ,Popovic S,Provias J,Cenic A

更新日期：2020-07-15 00:00:00

abstract：:Neuromuscular and vascular hamartoma (NMVH) is an unusual lesion presenting as intestinal obstruction by stricture formation. It is characterized by a hamartomatous mass comprising haphazardly arranged mesenchymal tissue native to the intestinal mucosa and submucosa. We aimed to characterize the clinicohistopathologic...

journal_title：International journal of surgical pathology

authors： Ayyanar P,Purkait S,Mishra TS,Patra S,Mitra S

更新日期：2020-06-01 00:00:00

abstract：:A 37-year-old woman was found to have multiple peritoneal nodules, including on the uterine serosa, at Cesarean section. Histology showed yellow crystalline material surrounded by histiocytes and occasional multinucleate giant cells. Further enquiry revealed that the patient underwent a cholecystectomy for a perforate...

journal_title：International journal of surgical pathology

authors： McVeigh G,McComiskey M,McCluggage WG

更新日期：2012-02-01 00:00:00

abstract：:Sinonasal adenocarcinoma is a rare tumor of the head and neck accounting for 10% to 20% of all primary malignancies of the nose and paranasal sinuses. There tumors are classified as salivary, intestinal and nonintestinal, nonsalivary. Low-grade nonintestinal nonsalivary are rare tumors whose diagnosis is essentially t...

journal_title：International journal of surgical pathology

authors： Blumberg JM,Escobar-Stein J,Vining EM,Prasad ML

更新日期：2015-12-01 00:00:00

abstract：:Spindle cell neoplasms arising in the testis are uncommon; most cases belong to the category of gonadal stromal tumors, and the presence of distinctive clinical and pathological features usually lead to a definitive diagnosis. In some instances, however, the diagnosis of these tumors can be challenging and special tec...

journal_title：International journal of surgical pathology

authors： Nistal M,Gonzalez-Peramato P,Serrano A,Reyes-Mugica M,Cajaiba MM

更新日期：2011-02-01 00:00:00

abstract：:Spermatocytic tumor, formerly known as spermatocytic seminoma, is an uncommon testicular neoplasm which is a distinct clinicopathologic entity from classic seminoma. These tumors are not associated with germ cell neoplasia in situ, other germ cell tumors, or isochromosome 12p. Although typically, these tumors have an ...

journal_title：International journal of surgical pathology

authors： Stueck AE,Grantmyre JE,Wood LA,Wang C,Merrimen J

更新日期：2017-09-01 00:00:00

abstract：:Primary pulmonary mucin-rich lesions with abundant goblet cells growing within alveolar spaces are either classified as mucinous adenocarcinoma (previously called mucinous bronchioloalveolar carcinoma) or colloid carcinoma. Some of these lesions display a morphologic pattern characterized by paucicellular discontinuou...

journal_title：International journal of surgical pathology

authors： Jessurun J

更新日期：2015-05-01 00:00:00

abstract：:We report the case of a well-differentiated chondrosarcoma of the proximal humerus in a 60-year-old man that featured a prominent component of granular cells, the granules being shown by electron microscopy to be lysosomal. Although secondary granular cell changes have been described in a large variety of tumor types,...

journal_title：International journal of surgical pathology

authors： Cremonini A,Kuhn E,De Biase P,Franchi A

更新日期：2006-04-01 00:00:00

abstract：:Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described entity that, despite significant pleomorphism, carries a good prognosis. We briefly describe this tumor and its principal differential diagnoses. Recognition of SCPFTs, including the clinical context in which they arise, is important to avoid...

journal_title：International journal of surgical pathology

authors： Foot O,Hallin M,Bagué S,Jones RL,Thway K

更新日期：2020-12-01 00:00:00

abstract：:Here we present the case of a 73-year-old woman with an ulcerated, advanced, hepatoid, and α-fetoprotein-producing poorly differentiated (G3) primary gastric adenocarcinoma pT3 N3a M1 with multinucleated cells and evident neuroendocrine component. This tumor was consistent with giant cell tumor type gastric carcinoma ...

journal_title：International journal of surgical pathology

authors： Wincewicz A,Kowalik A,Zięba S,Lewitowicz P,Góźdź S,Sulkowski S

更新日期：2015-10-01 00:00:00

abstract：:We assessed the contribution of histopathological features to systemic recurrence (SR) in patients with colorectal cancer, using a case-control design: 71 cases and 184 controls were included, with a mean time until SR of 1.4 ± 0.1 years and a mean follow-up of controls of 1.6 ± 0.06 years. Cases had significantly gre...

journal_title：International journal of surgical pathology

authors： Hayes BD,O'Riordan JM,Stuart C,Muldoon C

更新日期：2014-09-01 00:00:00

abstract：:Cutaneous glomeruloid hemangioma is a hallmark of POEMS syndrome. These patients have elevated serum levels of vascular endothelial growth factor. The authors report an extracutaneous uterine glomeruloid hemangioma in an 82-year-old woman with a history of breast and endometrial carcinomas. Within the lumen of myometr...

journal_title：International journal of surgical pathology

authors： Giner F,Compañ A,Monteagudo C

更新日期：2012-08-01 00:00:00

abstract：:Primary pulmonary acinic cell carcinoma (ACC) is rare. The clinicopathological features are not identical to that of classic ACC that leads to misdiagnosis. In this article, we summarized the clinicopathological features of 25 such cases, including 6 cases in this series and additional 19 cases in the literature. Pulm...

journal_title：International journal of surgical pathology

authors： Nie L,Zhou C,Wu H,Zhou Q,Meng F

更新日期：2019-09-01 00:00:00

abstract：:NET-1 is a member of the NET-x family. To explore the potential role of NET-1 in hepatocellular carcinoma (HCC), the expression of NET-1 and the relationship with HCC were examined for the first time. We found that NET-1 was frequently expressed in HCC and the peritumor tissue. The relative amounts of NET-1 mRNA in HC...

journal_title：International journal of surgical pathology

authors： Chen L,Wang Z,Zhan X,Li DC,Zhu YY,Zhu J

更新日期：2007-10-01 00:00:00

abstract：:We report a case of metaplastic columnar epithelium in the mid-esophagus in a patient with history of caustic ingestion. A cardiac-type gastric phenotype, with early signs of intestinalization, was confirmed by immunohistochemistry studies (MUC5AC, MUC6, SOX2, and CDX2). Nonmetaplastic mucosa had histologic evidence o...

journal_title：International journal of surgical pathology

authors： Rolim I,Rodrigues RV,Bettencourt A,Barros R,Camilo V,Dias Pereira A,Almeida R,Chaves P

更新日期：2017-05-01 00:00:00

abstract：:We review the clinical, pathologic, and molecular genetic features of 3 splenic T-cell-rich B-cell lymphomas and discuss their differential diagnosis. All patients presented with symptomatic splenomegaly and underwent diagnostic/therapeutic splenectomy. Microscopically, the spleen in all cases showed a micronodular pr...

journal_title：International journal of surgical pathology

authors： Li S,Mann KP,Holden JT

更新日期：2004-01-01 00:00:00

abstract：:Microvillous inclusion disease (MVID) is a congenital condition presenting with intractable diarrhea. Biopsies demonstrate abnormal apical PAS and CD10 staining in surface enterocytes correlating with the presence of characteristic cytoplasmic inclusions. MVID has been linked to mutations in myosin Vb, important in ap...

journal_title：International journal of surgical pathology

authors： Talmon G,Holzapfel M,DiMaio DJ,Muirhead D

更新日期：2012-06-01 00:00:00

abstract：:Tumor-to-tumor metastasis is an unusual phenomenon wherein one distinct malignancy is present within the substance of another independent tumor. This event is rare, difficult to detect with imaging, and, due to conflicting terminology in the literature, can be challenging to classify. This article reports the first do...

journal_title：International journal of surgical pathology

authors： Miller V,Hoellwarth JS,Hankins ML,McGough R,Schoedel K

更新日期：2020-04-01 00:00:00