Tissue microarrays in diffuse large B-cell lymphomas: are they really able to identify distinct prognostic groups in lymphomas of both nodal and extranodal origin?

abstract：:Ninety-eight consecutive surgical biopsies of oral mucosa from 96 patients were evaluated immunohistochemically with an anti-cytokeratin 20 (CK 20) anti-body to evidence Merkel cells (MC). Fifteen cases, showing the highest number of MC, were additionally studied with chromogranin A, S-100 protein, neuro filaments, ep...

journal_title：International journal of surgical pathology

authors： Righi A,Betts CM,Marchetti C,Marucci G,Montebugnoli L,Prati C,Eusebi LH,Muzzi L,Ragazzini T,Foschini MP

更新日期：2006-07-01 00:00:00

abstract：:Mammary-type myofibroblastoma (MFB) is a benign spindle cell tumor of the breast and soft tissue characterized by 13q14 alterations leading to loss of Rb-1 protein expression, a feature shared among spindle cell lipoma and cellular angiofibroma. In this article, we present a novel case of MFB arising in the left breas...

journal_title：International journal of surgical pathology

authors： Strait AM,Linos K,Tafe LJ,Muller KE

更新日期：2020-08-05 00:00:00

abstract：:To elucidate the relationship between del(5q) and the clinical and histological features of small cell neuroendocrine lung carcinoma, 33 tissue samples from patients with this tumor were evaluated. By using fluorescence in situ hybridization, del(5q) was identified in almost 50% of cases (15/33, 45%). Clinically, pati...

journal_title：International journal of surgical pathology

authors： Hartel PH,Shackelford AL,Hartel JV,Wenger SL

更新日期：2008-10-01 00:00:00

abstract：:Background. Solitary circumscribed neuroma (SCN), also known as palisaded encapsulated neuroma (PEN), is a benign neural tumor. It may be mistaken as either schwannoma or neurofibroma in pathology practice. In this study, we aimed to define clinicopathologic and immunohistochemical features and discuss its differentia...

journal_title：International journal of surgical pathology

authors： Leblebici C,Savli TC,Yeni B,Cin M,Aksu AEK

更新日期：2019-08-01 00:00:00

abstract：:CD138 (syndecan-1) immunoexpression has been reported to be specific for the plasmacytoid variant of urothelial carcinomas (UCs). The aim of this study was to examine the utility of CD138 immunohistochemistry for diagnosing the plasmacytoid variant of UCs. The extent and intensity of CD138 immunostaining were evaluate...

journal_title：International journal of surgical pathology

authors： Goto K

更新日期：2016-10-01 00:00:00

abstract：:Cells with a resemblance to Gaucher cells, sometimes called pseudo-Gaucher cells, are seen in the bone marrow of some patients with hematologic malignancy or anemia. These cells are derived from cells of the monocytic lineage but do not show the characteristic inclusions of true Gaucher cells when examined by electron...

journal_title：International journal of surgical pathology

authors： Stenzel P,Weeks DA

更新日期：2013-02-01 00:00:00

abstract：:The true incidence of light chain deposition disease (LCDD) restricted to the central nervous system (CNS) is unknown. To our knowledge only 7 cases of LCDD restricted to the brain have been previously reported. We herein describe an unusual example. A 44-year-old man presented with a history of ischemic retinopathy i...

journal_title：International journal of surgical pathology

authors： Mercado JJ,Markert JM,Meador W,Chapman P,Perry A,Hackney JR

更新日期：2017-12-01 00:00:00

abstract：:Diaphragm disease of small intestine usually presents with nonspecific clinical features. Radiological investigations often fail to differentiate it from small intestinal tumors and inflammatory bowel disease. It is therefore diagnosed on final histology after surgical resection. We hereby report an interesting case o...

journal_title：International journal of surgical pathology

authors： Ullah S,Ajab S,Rao R,Raghunathan G,DaCosta P

更新日期：2015-06-01 00:00:00

abstract：:Tumor-to-tumor metastasis is a very rare phenomenon. The most common donor and recipient of tumor-to-tumor metastasis are carcinomas of lung and renal cell carcinoma, respectively. We report a case of primary lung adenocarcinoma that metastasized into a renal angiomyolipoma 9 years after the resection of primary lung ...

journal_title：International journal of surgical pathology

authors： Wu PS,Pan CC

更新日期：2015-05-01 00:00:00

abstract：:Cystic squamous cell carcinomas (SCCs) of the jaws, including carcinoma cuniculatum, are rare, slow growing, and relentlessly invasive. The aim of this article is to present 12 cases, 4 of which were designated as carcinoma cuniculatum on the basis of deeply endophytic, anastomosing channels of cystic stratified squam...

journal_title：International journal of surgical pathology

authors： Barrett AW,Garg M,Armstrong D,Bisase BS,Newman L,Norris PM,Shelley M,Tighe JV,Hyde NC,Chaston NJ,Gulati A

更新日期：2020-09-01 00:00:00

abstract：:The aim of this study was to investigate the role of UbcH10 expression in the differential diagnosis of benign, hyperplastic, and malignant endometrial tissues and also the relationship of UbcH10 with the clinicopathologic parameters of malignant cases. A tissue microarray was performed for 81 endometrial curettage bi...

journal_title：International journal of surgical pathology

authors： Kefeli M,Yildiz L,Celik H,Tosun M,Karagoz F

更新日期：2012-08-01 00:00:00

abstract：:Appendiceal pneumatosis is rare, reported either in the context of acute appendicitis or enterocolitis. Here, we report the case of an elderly adult in whom the acute appendicitis was associated with pneumatosis and occurred in the context of a malformed appendix with pathogenic organism remnants. A 72-year-old man pr...

journal_title：International journal of surgical pathology

authors： Handra-Luca A,Bisseret D,Dragoescu E

更新日期：2016-02-01 00:00:00

abstract：:NET-1 is a member of the NET-x family. To explore the potential role of NET-1 in hepatocellular carcinoma (HCC), the expression of NET-1 and the relationship with HCC were examined for the first time. We found that NET-1 was frequently expressed in HCC and the peritumor tissue. The relative amounts of NET-1 mRNA in HC...

journal_title：International journal of surgical pathology

authors： Chen L,Wang Z,Zhan X,Li DC,Zhu YY,Zhu J

更新日期：2007-10-01 00:00:00

abstract：:Myositis ossificans (MO) and fibroosseous pseudotumor of digits (FP) are pseudotumoral mimics of malignancy. A review of 50 cases of MO and 14 cases of FP showed that a malignant diagnosis was suggested by referring pathologists in 23% of MO and 9% of FP. The most common misdiagnosis was osteosarcoma. Awareness of the...

journal_title：International journal of surgical pathology

authors： de Silva MV,Reid R

更新日期：2003-07-01 00:00:00

abstract：:Unlike their cutaneous counterparts, head and neck mucosal malignant melanomas (HNMM) behave much more aggressively and their prognostic markers have not been fully elucidated. Therefore, the aim of this study was to review the clinicopathologic features of a contemporary series of primary HNMM, retrieved from archiva...

journal_title：International journal of surgical pathology

authors： Kerr EH,Hameed O,Lewis JS Jr,Bartolucci AA,Wang D,Said-Al-Naief N

更新日期：2012-02-01 00:00:00

abstract：:Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases at the ...

journal_title：International journal of surgical pathology

authors： Toll AD,Mitchell D,Yeo CJ,Hruban RH,Witkiewicz AK

更新日期：2011-12-01 00:00:00

abstract：:Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described entity that, despite significant pleomorphism, carries a good prognosis. We briefly describe this tumor and its principal differential diagnoses. Recognition of SCPFTs, including the clinical context in which they arise, is important to avoid...

journal_title：International journal of surgical pathology

authors： Foot O,Hallin M,Bagué S,Jones RL,Thway K

更新日期：2020-12-01 00:00:00

abstract：:This study describes the clinical, histologic, and immunohistochemical features of four cases of GI PEComa. The size of the tumors ranged from 3.5 to 6.0cm in diameter, and all were located in wall of the large bowel. Microscopically, the tumors were characterized by an epithelioid arrangement of tumor cells, which ha...

journal_title：International journal of surgical pathology

authors： Shi HY,Wei LX,Sun L,Guo AT

更新日期：2010-08-01 00:00:00

abstract：:We report our experience with Chromogenic in Situ Hybridization (CISH) for the evaluation of HER2 amplification on 55 cases of formalin-fixed, paraffin-embedded invasive breast carcinomas of different histology. All the results were corrected for chromosome 17 aneusomy and compared with immunohistochemistry (IHC); a s...

journal_title：International journal of surgical pathology

authors： Li-Ning-T E,Ronchetti R,Torres-Cabala C,Merino MJ

更新日期：2005-10-01 00:00:00

abstract：:SMARCB1 (INI1) deficient sinonasal carcinoma is a recently recognized entity with wide histomorphologic spectrum. We present a case of this carcinoma that contained, in addition to a "common" morphology, scattered foci of yolk sac tumor differentiation. The tumor occurred in paranasal sinuses in a 44-year-old woman. I...

journal_title：International journal of surgical pathology

authors： Zamecnik M,Rychnovsky J,Syrovatka J

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Phyllodes tumors (PTs) of the breast are rare biphasic neoplasms and are classified as benign, borderline, or malignant. Many biological markers have been studied to discriminate between different grades of PTs. IMP3 is a member of the insulin-like growth factor II mRNA binding protein (IMP) family and is ex...

journal_title：International journal of surgical pathology

authors： Bellezza G,Prosperi E,Del Sordo R,Colella R,Rulli A,Sidoni A

更新日期：2016-02-01 00:00:00

abstract：AIMS. GIARDIA:is sometimes missed by the pathologist, and we sought to determine how often this occurs at our institution-a large tertiary care center with a subspecialty gastrointestinal pathology service and what certain clinical and histologic clues can be used to flag cases with a higher likelihood of infection, ta...

journal_title：International journal of surgical pathology

authors： Shen MJ,Voltaggio L,Robertson S

更新日期：2020-08-10 00:00:00

abstract：:Reduction mammoplasty is a frequently performed procedure for the treatment of macromastia and for the achievement of symmetry in breast cancer patients following lumpectomy. Slides from 516 consecutive bilateral reduction mammoplasties performed for macromastia over 15 years were reviewed. Among these, 92 (18%) low-r...

journal_title：International journal of surgical pathology

authors： Dotto J,Kluk M,Geramizadeh B,Tavassoli FA

更新日期：2008-01-01 00:00:00

abstract：:Pseudomembranes in colonic biopsies are normally associated with antibiotic related pseudomembranous colitis. Although pseudomembranes have rarely been reported in other conditions, their presence in rectal prolapse has not been previously reported. ...

journal_title：International journal of surgical pathology

authors： Coyne JD

更新日期：2013-08-01 00:00:00

abstract：:The purpose of our study was to investigate the diagnostic value of expression of IMP3, nucleophosmin, and correlation of these markers with Ki-67 proliferation index in papillary thyroid carcinoma and benign neoplasms of thyroid gland. The aim was also to investigate whether there is a difference between papillary an...

journal_title：International journal of surgical pathology

authors： Yorukoglu A,Yalcin N,Avci A,Cakalagaoglu F,Yaylali G,Akin F,Haciyanli M,Ozden A

更新日期：2015-02-01 00:00:00

abstract：:Polyoma virus nephritis is increasingly being recognized as a cause of allograft dysfunction in renal transplant patients. We describe and illustrate the findings in a renal biopsy and a concurrent urine sample from a patient with polyoma virus nephritis. The urine cytology findings were highly suggestive of a tumor d...

journal_title：International journal of surgical pathology

authors： Papadimitriou JC,Drachenberg CB,Bourquin PM

更新日期：2000-10-01 00:00:00

abstract：:To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...

journal_title：International journal of surgical pathology

authors： Rao Q,Chen JY,Wang JD,Ma HH,Zhou HB,Lu ZF,Zhou XJ

更新日期：2011-04-01 00:00:00

abstract：:Enfuvirtide (ENF, T-20, or Fuzeon [Hoffman-La Roche Inc, Nutley, NJ, and Trimeris, Inc, Durham, NC]) is an HIV-1 fusion inhibitor and is the only injectable antiretroviral drug available. Injection site reactions (ISRs) are the most frequently reported adverse events, occurring in about 98% of patients. A granuloma an...

journal_title：International journal of surgical pathology

authors： Sidhu HK,Chaffee BH,Tvetenstrand CD,Sidhu JS

更新日期：2010-10-01 00:00:00

abstract：:Primary carcinoid tumor of the skin (PCTS) is an uncommon indolent neoplasm, with 10 cases described in the literature. The tumors affect patients in the sixth to ninth decades of life (mean = 66.3 years) with an equal gender distribution and predilection for the head and trunk. They present as slowly enlarging nodule...

journal_title：International journal of surgical pathology

authors： Jedrych J,Pulitzer M

更新日期：2014-04-01 00:00:00

abstract：:Metastases to cervical lymph nodes (LNs) are an important independent adverse indicator in the prognosis of oral squamous cell carcinoma (OSCC). An accurate evaluation of molecular patterns favoring the metastatic process can be helpful in predicting cases of OSCC with elevated probability of early or late metastases ...

journal_title：International journal of surgical pathology

authors： Foschini MP,Leonardi E,Eusebi LH,Farnedi A,Poli T,Tarsitano A,Cocchi R,Marchetti C,Gentile L,Sesenna E,Marucci G,Montebugnoli L

更新日期：2013-04-01 00:00:00