Podoplanin and E-cadherin expression in preoperative incisional biopsies of oral squamous cell carcinoma is related to lymph node metastases.

abstract：:Ninety-eight consecutive surgical biopsies of oral mucosa from 96 patients were evaluated immunohistochemically with an anti-cytokeratin 20 (CK 20) anti-body to evidence Merkel cells (MC). Fifteen cases, showing the highest number of MC, were additionally studied with chromogranin A, S-100 protein, neuro filaments, ep...

journal_title：International journal of surgical pathology

authors： Righi A,Betts CM,Marchetti C,Marucci G,Montebugnoli L,Prati C,Eusebi LH,Muzzi L,Ragazzini T,Foschini MP

更新日期：2006-07-01 00:00:00

abstract：:In this study based on the study of a centromeric DNA probe specific for chromosome 8 the authors standardized a method for the enzymatic detection of specific chromosome copy numbers on interphase nuclei from tumor tissue samples. Since the in situ hybridization (ISH) of chromosome 8 specific probe was revealed with ...

journal_title：International journal of surgical pathology

authors： Buonamici L,Serra M,Losi L,Eusebi V

更新日期：2000-07-01 00:00:00

abstract：:We review the clinical, pathologic, and molecular genetic features of 3 splenic T-cell-rich B-cell lymphomas and discuss their differential diagnosis. All patients presented with symptomatic splenomegaly and underwent diagnostic/therapeutic splenectomy. Microscopically, the spleen in all cases showed a micronodular pr...

journal_title：International journal of surgical pathology

authors： Li S,Mann KP,Holden JT

更新日期：2004-01-01 00:00:00

abstract：:Clear cell chondrosarcoma (CCCS) is a rare variant of conventional chondrosarcoma with low-grade malignant features that may be confused radiographically and histologically with chondroblastoma. We report a case of a 50-year-old female who presented with 6 months of left hip pain. Initial radiographs demonstrated an o...

journal_title：International journal of surgical pathology

authors： Kiefer RM,Wojcik J,Cooper K,Weber KL,Sebro R

更新日期：2018-12-01 00:00:00

abstract：:The aim of this study was to investigate the role of UbcH10 expression in the differential diagnosis of benign, hyperplastic, and malignant endometrial tissues and also the relationship of UbcH10 with the clinicopathologic parameters of malignant cases. A tissue microarray was performed for 81 endometrial curettage bi...

journal_title：International journal of surgical pathology

authors： Kefeli M,Yildiz L,Celik H,Tosun M,Karagoz F

更新日期：2012-08-01 00:00:00

abstract：:Synovial sarcoma is a high-grade sarcoma commonly affecting young adults. The sites of involvement include soft tissue near joints, lung, pleura, mediastinum, larynx, kidney, and buttocks. Histologic types include monophasic, biphasic, and undifferentiated. We report a unique case of synovial sarcoma with low-grade hi...

journal_title：International journal of surgical pathology

authors： Gupta N,Kenan S,Kahn LB

更新日期：2018-02-01 00:00:00

abstract：:Mucoepidermoid carcinoma (MEC) shows a wide morphologic spectrum, including epithelium with oncocytic or squamous metaplastic changes overlying a prominent cystic architecture, as well as tumor-associated lymphoid tissue. We illustrate a case of MEC of the parotid in a 17-year-old female, in which all these features o...

journal_title：International journal of surgical pathology

authors： Heatley N,Harrington KJ,Thway K

更新日期：2018-02-01 00:00:00

abstract：:Micrometastases in lymph nodes and blood may provide important prognostic information. In this study, cytokeratin 20 (CK20) positive cells in lymph nodes and circulating CK20 mRNA were studied using 57 paraffin-embedded lymph node specimens and blood from 24 patients with pN0 colorectal cancer (CRC), respectively. Res...

journal_title：International journal of surgical pathology

authors： Wong CS,Cheung MT,Ma BB,Pun Hui E,Chan AC,Chan CK,Lee KC,Cheuk W,Lam MY,Wong MC,Chan CM,Chan JK,Chan AT

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Study of minimum adenocarcinoma has been done almost exclusively on conventional acinar adenocarcinoma. Pseudohyperplastic adenocarcinoma can be confused with benign lesions because of its well-differentiated appearance and has not been studied when the biopsy shows few malignant glands (limited carcinoma). ...

journal_title：International journal of surgical pathology

authors： Arista-Nasr J,Martinez-Benitez B,Mijangos-Trejo A,Bornstein-Quevedo L,Albores-Saavedra J

更新日期：2017-10-01 00:00:00

abstract：:Lynch syndrome is a hereditary disease with germline mutation in a DNA mismatch repair gene, most often presenting with colorectal and/or endometrial carcinomas; however, the spectrum of Lynch syndrome-associated tumors is expanding. In this article, we report a case of a primary peritoneal epithelioid mesothelioma th...

journal_title：International journal of surgical pathology

authors： Lu Y,Milchgrub S,Khatri G,Gopal P

更新日期：2017-05-01 00:00:00

abstract：:Enfuvirtide (ENF, T-20, or Fuzeon [Hoffman-La Roche Inc, Nutley, NJ, and Trimeris, Inc, Durham, NC]) is an HIV-1 fusion inhibitor and is the only injectable antiretroviral drug available. Injection site reactions (ISRs) are the most frequently reported adverse events, occurring in about 98% of patients. A granuloma an...

journal_title：International journal of surgical pathology

authors： Sidhu HK,Chaffee BH,Tvetenstrand CD,Sidhu JS

更新日期：2010-10-01 00:00:00

abstract：:We report the case of a well-differentiated chondrosarcoma of the proximal humerus in a 60-year-old man that featured a prominent component of granular cells, the granules being shown by electron microscopy to be lysosomal. Although secondary granular cell changes have been described in a large variety of tumor types,...

journal_title：International journal of surgical pathology

authors： Cremonini A,Kuhn E,De Biase P,Franchi A

更新日期：2006-04-01 00:00:00

abstract：:Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases at the ...

journal_title：International journal of surgical pathology

authors： Toll AD,Mitchell D,Yeo CJ,Hruban RH,Witkiewicz AK

更新日期：2011-12-01 00:00:00

abstract：:Mixed squamous and glandular papilloma (mixed papilloma) of the lung has been reported in fewer than 25 cases in the English literature. Although it is known as a benign tumor, malignant transformation has been reported. Papillary cystic carcinoma is characterized by papillary and cystic growth patterns and has been r...

journal_title：International journal of surgical pathology

authors： An AR,Park SY,Kim JH,Chae KJ,Chung MJ

更新日期：2020-09-01 00:00:00

abstract：:Gastric duplication cysts are rare congenital anomalies that are mostly discovered in children but can remain asymptomatic and undetected into adulthood. Malignant transformation in gastric duplications is extremely rare, with most reported cases being adenocarcinomas. Herein, the authors report the first case of a hi...

journal_title：International journal of surgical pathology

authors： Horne G,Ming-Lum C,Kirkpatrick AW,Parker RL

更新日期：2007-04-01 00:00:00

abstract：:Lymphoplasmacyte-rich meningioma (LPRM) is an extremely rare variant of meningioma, and a small percentage of LPRM may be associated with IgG4-related disease. To date, the coexistence of 2 rare meningioma variants consisting of LPRM and angiomatous meningioma within one neoplasm has not been reported in the literatur...

journal_title：International journal of surgical pathology

authors： Son HJ,Yu IK,Kim SM

更新日期：2018-02-01 00:00:00

abstract：:In this study, we examined aberrant methylation of the E-cadherin, estrogen receptor, RB1 , p16, p15, p14, and MGMT genes by the methylation-specific polymerase chain reaction method in 101 gastric carcinomas. Hypermethylation was detected in E-cadherin, estrogen receptor, RB1, p16, p14, p15, and MGMT at the rates of ...

journal_title：International journal of surgical pathology

authors： Zhao YF,Zhang YG,Tian XX,Juan Du,Jie Zheng

更新日期：2007-07-01 00:00:00

abstract：:Aims Epithelial mesenchymal transition (EMT) is a crucial process for acquisition of malignant phenotype, aggressiveness, and metastatic capacity in neoplasms. It is characterized by loss of epithelial markers and gain of mesenchymal markers. Studies on EMT and its potential association with the histological grading a...

journal_title：International journal of surgical pathology

authors： Angadi PV,Patil PV,Angadi V,Mane D,Shekar S,Hallikerimath S,Kale AD,Kardesai SG

更新日期：2016-12-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) with primary involvement of the upper gastrointestinal (GI) tract is rare. We report 2 adult cases of localized LCH in the upper-GI tract, including the second reported adult case of esophageal LCH and review 11 previously reported cases. Case 1 involved the esophagus of a 61-year-o...

journal_title：International journal of surgical pathology

authors： Matsuoka Y,Iemura Y,Fujimoto M,Shibuya S,Yamada A,Fujii S,Kusaka T,Shindo T,Minamiguchi S,Haga H

更新日期：2020-10-09 00:00:00

abstract：:In keeping with the stated goal of providing the surgical pathologist with tools to recognize abnormalities of the gastrointestinal (GI) tract due to drugs (AGIDS), in part II of this review we embark in a more organ-based description of AGIDS. Adequate space is given to the numerous adverse gastrointestinal effects o...

journal_title：International journal of surgical pathology

authors： De Petris G,Caldero SG,Chen L,Xiao SY,Dhungel BM,Spizcka AJ,Lam-Himlin D

更新日期：2014-05-01 00:00:00

abstract：:Germinotropic lymphoproliferative disorder (GLPD) is a poorly characterized lymphoproliferative entity, recently included in the World Health Organization classification of hematolymphoid neoplasms. The histological pattern of this disease comprises monotypic plasmablasts that involve the germinal centers of the lymph...

journal_title：International journal of surgical pathology

authors： Martinez-Ciarpaglini C,Valkov A,Hurtado M,Agustí J,Malave G,Ferrández A

更新日期：2020-10-01 00:00:00

abstract：:Renal cell carcinoma (RCC) in children and young adults is rare and pathologically problematic. RCC can be either hereditary or sporadic and has a guarded prognosis because appropriate management has not been established. A case of RCC in an 11-year-old is reported. The clinical presentation was a right abdominal mass...

journal_title：International journal of surgical pathology

authors： Winarti NW,Argani P,De Marzo AM,Hicks J,Mulyadi K

更新日期：2008-01-01 00:00:00

abstract：:Transitional cell tumors of the ovary comprise about 1% to 2% of all ovarian neoplasms. Most of these tumors are benign Brenner tumors and account for about 5% of benign surface epithelial-stromal tumors. Spicules of calcifications are found in the stroma of about 50% of benign Brenner tumors. Although diagnostic chal...

journal_title：International journal of surgical pathology

authors： Vemavarapu L,Alatassi H,Moghadamfalahi M

更新日期：2011-02-01 00:00:00

abstract：:Rhabdomyosarcoma is an aggressive malignant tumor often developing in the head and neck in children. In the sinonasal region, rhabdomyosarcoma constitutes a clinically important group because of the difficulty of surgical resection and its generally poor prognosis. We reviewed the archival pathology materials of 39 ca...

journal_title：International journal of surgical pathology

authors： Ahmed AA,Tsokos M

更新日期：2007-04-01 00:00:00

abstract：:Male breast carcinomas (MBCs) are rare neoplasms that account for 0.1% of all male cancers. Still, there are 2000 new cases of MCB diagnosed annually in the United States. Because of its rarity, data regarding the etiology, risk factors, diagnosis, management, and prognosis of MBC are limited. MBC shares some similari...

journal_title：International journal of surgical pathology

authors： Javidiparsijani S,Rosen LE,Gattuso P

更新日期：2017-05-01 00:00:00

abstract：CONTEXT.:Follicular cholecystitis (FC) is a poorly characterized entity. OBJECTIVE.:To determine its frequency/clinicopathologic associations. DESIGN.:A total of 2550 cholecystectomy specimens were examined. Two hundred three of these were consecutive routine cholecystectomies submitted entirely for microscopic exami...

journal_title：International journal of surgical pathology

authors： Saka B,Memis B,Seven IE,Pehlivanoglu B,Balci S,Bagci P,Reid M,Dursun N,Escalano OT,Roa JC,Araya JC,Kong SY,Basturk O,Koshiol J,Adsay NV

更新日期：2020-12-01 00:00:00

abstract：:The development of squamous metaplasia or carcinoma is a rare occurrence in the setting of a ruptured or leaking silicone breast implant capsule. However, the oncogenic process in such a context is yet another intriguing example of how chronic inflammation plays an integral role in the tumorigenic process. Recent pape...

journal_title：International journal of surgical pathology

authors： Alikhan MB,Nassar A,Mansoor I

更新日期：2010-12-01 00:00:00

abstract：:Cervical cancer is the most common gynecologic malignancy of the developing world. The oncogenic role of human papilloma virus (HPV) is well known. Attention is now focusing on the complicit genetic changes, which allow progression of these tumors. Regarding these changes, deletion of tumor suppressor genes (loss of h...

journal_title：International journal of surgical pathology

authors： Clarke B,Gordon M,Moodley M,Naidoo R,Chetty R

更新日期：2003-10-01 00:00:00

abstract：:Primary pulmonary mucin-rich lesions with abundant goblet cells growing within alveolar spaces are either classified as mucinous adenocarcinoma (previously called mucinous bronchioloalveolar carcinoma) or colloid carcinoma. Some of these lesions display a morphologic pattern characterized by paucicellular discontinuou...

journal_title：International journal of surgical pathology

authors： Jessurun J

更新日期：2015-05-01 00:00:00

abstract：:Transformation of an ameloblastic fibroma to an ameloblastic fibrosarcoma has been reported rarely in the literature. The present case report describes such evolution in a patient under long-term follow-up. The patient was first treated in 2008, and he developed the malignant counterpart of the disease 2 years later. ...

journal_title：International journal of surgical pathology

authors： Bertoni F,Del Corso G,Bacchini P,Marchetti C,Tarsitano A

更新日期：2016-10-01 00:00:00