Abstract:
:Malignant melanoma has a variety of morphologic patterns and can metastasize and mimic any type of neoplastic process creating significant diagnostic difficulty. When metastasis to the gastrointestinal system is identified, it is most commonly associated with widely metastatic disease. We report a rare case of isolated gallbladder intramucosal metastatic melanoma with features mimicking lymphoepithelial carcinoma in an adult patient who presented with cholecystitis. Additionally, we report the imaging and morphologic features and discuss the importance of these findings along with a clear clinical history and immunohistochemical profile to make a definitive diagnosis.
journal_name
Int J Surg Patholjournal_title
International journal of surgical pathologyauthors
Lo AA,Peevey J,Lo EC,Guitart J,Rao MS,Yang GYdoi
10.1177/1066896915588932subject
Has Abstractpub_date
2015-08-01 00:00:00pages
409-13issue
5eissn
1066-8969issn
1940-2465pii
1066896915588932journal_volume
23pub_type
杂志文章abstract::Ulcerative colitis-related epithelial dysplasia represents a premalignant lesion, which may lead to the development of ulcerative colitis-related adenocarcinoma. The proper management of this condition requires proctocolectomy before the acquisition of the invasive phenotype. Patients with chronic ulcerative colitis, ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690000800106
更新日期:2000-01-01 00:00:00
abstract::Colorectal liver metastases with intrabiliary growth are uncommon and difficult to characterize by radiology alone. We present the case of a 61-year-old woman previously operated on for a left colon cancer who developed a metacronous lesion at liver segment II-III. Radiologic workup was indicative for cholangiocarcino...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896913491317
更新日期:2014-05-01 00:00:00
abstract::Appendiceal pneumatosis is rare, reported either in the context of acute appendicitis or enterocolitis. Here, we report the case of an elderly adult in whom the acute appendicitis was associated with pneumatosis and occurred in the context of a malformed appendix with pathogenic organism remnants. A 72-year-old man pr...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915597750
更新日期:2016-02-01 00:00:00
abstract::Sentinel lymph node biopsy is the current standard procedure used to stage patients with breast cancer. The best histological method in evaluating sentinel nodes is highly debated among institutions and is thus not standardized. The optimal histological analysis is a balance between comprehensive evaluation of the sen...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915596811
更新日期:2015-10-01 00:00:00
abstract::Rosai-Dorfman disease (RDD; sinus histiocytosis with massive lymphoadenopathy) is a rare, usually nodal self-limited disease. Sometimes nodal disease is coupled with extranodal localizations, in which case the disease can follow a protracted clinical course characterized by remissions and relapses and, exceptionally, ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908329590
更新日期:2010-12-01 00:00:00
abstract::In this article, we report the case of a 40-year-old woman with a sessile polyp of the rectosigmoid junction that underwent endoscopic resection. The resected specimen showed spindle cell proliferation with eosinophilic cytoplasm between mucosal crypts, mimicking mucosal prolapse syndrome. However, these were immunohi...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896918818897
更新日期:2019-08-01 00:00:00
abstract::Rare cases of metastasis to uterine polyps have been reported in English literature but not, to the best of our knowledge, to uterine adenomyomas. All these cases are represented by breast cancer, most of them involving tamoxifen-associated polyps. We first report a case of cutaneous malignant melanoma metastatic to u...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/106689690501300217
更新日期:2005-04-01 00:00:00
abstract::Because of its rarity, pathologic and clinical features of Hodgkin lymphoma-like posttransplant lymphoproliferative disorder (HL-like PTLD) are not well understood, and it is unclear whether its biological behavior is more closely related to classical Hodgkin disease or to monomorphic B-cell PTLD. The authors compared...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896909338597
更新日期:2010-08-01 00:00:00
abstract::A 46-year-old man presented with nonproductive cough and lower limb swelling. Chest radiograph showed a left lower lobe lung mass and multiple subpleural nodules. Other investigations revealed that he had nephrotic syndrome. Core biopsies of the left lower lobe lung mass showed features of inflammatory pseudotumor wit...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920928584
更新日期:2021-02-01 00:00:00
abstract::Mixed adenoneuroendocrine carcinomas (MANECs) of the biliary tract are rare tumors, and to date only a few cases arising in the gallbladder have been reported. Their histogenesis is a matter of debate, since the biliary tract normally lacks neuroendocrine cells. However, the immunohistochemical identification of nonne...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896915580433
更新日期:2015-08-01 00:00:00
abstract::A 16-year-old boy presented with a tumor located in fourth ventricle, which showed histological features of an ependymoma replete with perivascular pseudorosettes and true ependymal rosettes. Interestingly, many of the tumor cells exhibited abundant cytoplasm stuffed with a grayish brown pigment. Histochemical stains ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920926700
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Acetylcholinesterase (AchE) histochemistry has been established as an accurate diagnostic tool for Hirschsprung's disease (HD). In addition, calretinin immunohistochemistry is also reported as a reliable and adjunctive method to diagnose HD. We investigated the diagnostic value of combined AchE histochemistr...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896918761235
更新日期:2018-09-01 00:00:00
abstract::The aim of this study is to analyze all the cases of benign fibro-osseous lesions treated at School and Hospital of Stomatology, Wuhan University, to compare the results obtained in this study with those previously documented by other authors. The 127 cases diagnosed as a fibro-osseous lesion were retrieved, and infor...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896908318744
更新日期:2009-04-01 00:00:00
abstract::In this article, we report a very rare case of secondary angiosarcoma in a young woman with no prior history of breast cancer who had bilateral prophylactic mastectomies with autologous reconstruction due to a strong family history of breast cancer and BRCA1 gene variant of uncertain significance. The surgery was comp...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920930100
更新日期:2020-06-18 00:00:00
abstract::Anaplastic sarcoma of the kidney (ASK) is an extremely rare tumor, which usually presents as a large renal mass. Microscopically, the tumor is composed of pleomorphic mesenchymal spindle cells with marked atypia, associated with chondroid differentiation and focal round primitive mesenchymal cells. Herein, we present ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896916639373
更新日期:2016-09-01 00:00:00
abstract::Tumor-to-tumor metastasis is an unusual phenomenon wherein one distinct malignancy is present within the substance of another independent tumor. This event is rare, difficult to detect with imaging, and, due to conflicting terminology in the literature, can be challenging to classify. This article reports the first do...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896919872805
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:The rate of incidental prostate adenocarcinoma (PCa) detection in radical cystoprostatectomy (RCP) varies widely, ranging from 15% to 54%. Such variability may be explained by institutional differences in prostate grossing protocols. Either partial or complete submission of the prostate gland in RCP may resu...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896917696745
更新日期:2017-08-01 00:00:00
abstract::Primary leiomyosarcoma arising from the ovarian vein is extremely rare, with only 10 cases reported in the literature. We report on a case of leiomyosarcoma of the left ovarian vein in a 67-year-old woman who presented with abdominal discomfort. Pelvic ultrasound revealed a large, solid, irregular mass in close relati...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896916679888
更新日期:2017-06-01 00:00:00
abstract:CONTEXT.:Follicular cholecystitis (FC) is a poorly characterized entity. OBJECTIVE.:To determine its frequency/clinicopathologic associations. DESIGN.:A total of 2550 cholecystectomy specimens were examined. Two hundred three of these were consecutive routine cholecystectomies submitted entirely for microscopic exami...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920924079
更新日期:2020-12-01 00:00:00
abstract::Metastases to cervical lymph nodes (LNs) are an important independent adverse indicator in the prognosis of oral squamous cell carcinoma (OSCC). An accurate evaluation of molecular patterns favoring the metastatic process can be helpful in predicting cases of OSCC with elevated probability of early or late metastases ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896912471851
更新日期:2013-04-01 00:00:00
abstract::Merkel cell carcinoma (MCC) is a rare entity that most commonly arises from the skin. Angiosarcoma (AS) is a rare malignancy with a predilection for elderly males, has endothelial differentiation and a notoriously poor prognosis despite aggressive therapy. Herein, we report an angiosarcoma colliding with a MCC, in a p...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896919880260
更新日期:2020-05-01 00:00:00
abstract::Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases at the ...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896909339912
更新日期:2011-12-01 00:00:00
abstract::Germinotropic lymphoproliferative disorder (GLPD) is a poorly characterized lymphoproliferative entity, recently included in the World Health Organization classification of hematolymphoid neoplasms. The histological pattern of this disease comprises monotypic plasmablasts that involve the germinal centers of the lymph...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896920921238
更新日期:2020-10-01 00:00:00
abstract::Mesonephric adenocarcinoma is a rare tumor type that is usually found in areas where the Wolffian duct was present during the fetal period. We report a case of mesonephric adenocarcinoma of the uterine corpus in a 66-year-old woman who presented with vaginal bleeding. Pelvic magnetic resonance imaging revealed a 2.7-c...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896915611489
更新日期:2016-04-01 00:00:00
abstract::Calcifying epithelial odontogenic tumor, also known as Pindborg tumor, is a rare benign odontogenic tumor. This tumor predominantly involves the mandible, though the maxilla can also be involved in some cases. The involvement of maxillary sinuses, however, has been previously reported in only 8 case reports English li...
journal_title:International journal of surgical pathology
pub_type: 杂志文章,评审
doi:10.1177/1066896916644782
更新日期:2016-09-01 00:00:00
abstract::To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896909354337
更新日期:2011-04-01 00:00:00
abstract::Renal cell carcinoma (RCC) in children and young adults is rare and pathologically problematic. RCC can be either hereditary or sporadic and has a guarded prognosis because appropriate management has not been established. A case of RCC in an 11-year-old is reported. The clinical presentation was a right abdominal mass...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896907304994
更新日期:2008-01-01 00:00:00
abstract::A 72-year-old man had a unilateral pleural effusion and multiple bilateral pulmonary nodules. Thoracoscopic biopsy revealed multiple discrete nodules in the pleura and lung. The latter consisted of tall columnar malignant cells arranged on alveolar surfaces in a lepidic growth pattern. Mucin filled the alveolar lumina...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896906290363
更新日期:2006-07-01 00:00:00
abstract::This study describes the clinical, histologic, and immunohistochemical features of four cases of GI PEComa. The size of the tumors ranged from 3.5 to 6.0cm in diameter, and all were located in wall of the large bowel. Microscopically, the tumors were characterized by an epithelioid arrangement of tumor cells, which ha...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896908330481
更新日期:2010-08-01 00:00:00
abstract::Background. Solitary circumscribed neuroma (SCN), also known as palisaded encapsulated neuroma (PEN), is a benign neural tumor. It may be mistaken as either schwannoma or neurofibroma in pathology practice. In this study, we aimed to define clinicopathologic and immunohistochemical features and discuss its differentia...
journal_title:International journal of surgical pathology
pub_type: 杂志文章
doi:10.1177/1066896919833172
更新日期:2019-08-01 00:00:00