Focal divergent chondrosarcomatous differentiation in a primary pleomorphic liposarcoma and expression of transforming growth factor beta.

Abstract:

:A rare case of primary pleomorphic liposarcoma of the thigh with a myxoid component, in which divergent differentiation to a well-differentiated chondrosarcoma was focally present, is described. Presence of heterologous elements has mainly been recognized in the context of dedifferentiated liposarcomas. Few cases of benign mesenchymal tissue have also been reported in well-differentiated and myxoid liposarcomas, while divergent sarcomatous differentiation in liposarcomas appears to be also rare in the absence of dedifferentiation. Positive immunostaining of transforming growth factor-beta, which seems to play a role in the formation of bone and cartilage, was demonstrated in our case. Review of the existing literature on the subject has been carried out.

journal_name

Int J Surg Pathol

authors

Panoussopoulos D,Theodoropoulos G,Lazaris AC,Papadimitriou K

doi

10.1177/106689690401200115

keywords:

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

79-85

issue

1

eissn

1066-8969

issn

1940-2465

journal_volume

12

pub_type

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