Invasive Lobular Carcinoma With Extensive Clear Cells: A Pitfall in Diagnosis.

abstract：:We report our experience with Chromogenic in Situ Hybridization (CISH) for the evaluation of HER2 amplification on 55 cases of formalin-fixed, paraffin-embedded invasive breast carcinomas of different histology. All the results were corrected for chromosome 17 aneusomy and compared with immunohistochemistry (IHC); a s...

journal_title：International journal of surgical pathology

authors： Li-Ning-T E,Ronchetti R,Torres-Cabala C,Merino MJ

更新日期：2005-10-01 00:00:00

abstract：:Tissue contaminants in anatomical pathology are not uncommon. While issues related to the presence of extraneous tissue on glass slides are often easily resolved, this is not always the case and several factors may contribute to diagnostic difficulty. Because of this, familiarity with the different steps involved in h...

journal_title：International journal of surgical pathology

authors： Hodgson AJ,Shang YM,Boulianne P,Downes MR,Hwang D,Slodkowska E

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Protein kinase C βII promotes melanogenesis and affects proliferation of melanocytic cells but is frequently absent or decreased in melanoma cells in vitro. OBJECTIVE:To investigate PKC-βII expression and spatial distribution within a lesion in various benign and malignant melanocytic proliferations. METHO...

journal_title：International journal of surgical pathology

authors： Krasagakis K,Tsentelierou E,Chlouverakis G,Stathopoulos EN

更新日期：2017-09-01 00:00:00

abstract：AIMS:Diffuse large B-cell lymphomas (DLBCL) can be divided into different subgroups (germinal center B-cell-like [GCB] and non-GCB) according to their gene expression profiles. Immunohistochemistry has been proposed as a surrogate for identifying these subgroups, but data about its efficacy in providing prognostic info...

journal_title：International journal of surgical pathology

authors： Laszlo D,Pruneri G,Andreola G,Radice D,Calabrese L,Rafaniello PR,Nassi L,Sammassimo S,Alietti A,Agazzi A,Vanazzi A,Martinelli G

更新日期：2011-08-01 00:00:00

abstract：AIM:To describe a case of metastasis of malignant peritoneal epithelioid mesothelioma in gastric antral mucosa in a patient with a cryptogenic liver cirrhosis associated with esophageal varices, abdominal pain and distension, ascites, and weight loss. MATERIALS AND METHOD:The patient underwent esophageal gastric endos...

journal_title：International journal of surgical pathology

authors： Daniele L,Righi A,Ferraris A,Macrì L,Asioli S

更新日期：2011-04-01 00:00:00

abstract：:Specimen misidentification is a common cause of errors in surgical pathology. We report a case where bone-marrow biopsies from patients of different genders were mislabeled and molecular methods were applied to resolve the identity. A short tandem repeat (STR)-polymerase chain reaction-based assay, commonly used in pa...

journal_title：International journal of surgical pathology

authors： Mariappan MR,Zehnder J,Arber DA,Lay M,Fadare O,Schrijver I

更新日期：2005-07-01 00:00:00

abstract：:To elucidate the relationship between del(5q) and the clinical and histological features of small cell neuroendocrine lung carcinoma, 33 tissue samples from patients with this tumor were evaluated. By using fluorescence in situ hybridization, del(5q) was identified in almost 50% of cases (15/33, 45%). Clinically, pati...

journal_title：International journal of surgical pathology

authors： Hartel PH,Shackelford AL,Hartel JV,Wenger SL

更新日期：2008-10-01 00:00:00

abstract：:The aim of this study was to investigate protein expression of adenomatous polyposis coli (APC) in primary and metastatic serous ovarian carcinoma. The expression of beta-catenin and E-cadherin was additionally analyzed. One hundred and thirteen primary (n = 56) and metastatic (n = 57) lesions were immunohistochemical...

journal_title：International journal of surgical pathology

authors： Karbova E,Davidson B,Metodiev K,Tropé CG,Nesland JM

更新日期：2002-07-01 00:00:00

abstract：:Lynch syndrome is a hereditary disease with germline mutation in a DNA mismatch repair gene, most often presenting with colorectal and/or endometrial carcinomas; however, the spectrum of Lynch syndrome-associated tumors is expanding. In this article, we report a case of a primary peritoneal epithelioid mesothelioma th...

journal_title：International journal of surgical pathology

authors： Lu Y,Milchgrub S,Khatri G,Gopal P

更新日期：2017-05-01 00:00:00

abstract：:Tumor-to-tumor metastasis is a very rare phenomenon. The most common donor and recipient of tumor-to-tumor metastasis are carcinomas of lung and renal cell carcinoma, respectively. We report a case of primary lung adenocarcinoma that metastasized into a renal angiomyolipoma 9 years after the resection of primary lung ...

journal_title：International journal of surgical pathology

authors： Wu PS,Pan CC

更新日期：2015-05-01 00:00:00

abstract：:A completely infarcted lymph node should alert the pathologist to the high possibility of malignant lymphoma. The lymph node lesion of infectious mononucleosis (IM) shows marked histologic diversity and occasionally may be confused with malignant lymphoma. We report a rare case of IM showing extensive lymph node infar...

journal_title：International journal of surgical pathology

authors： Kojima M,Nakamura S,Sugihara S,Sakata N,Masawa N

更新日期：2002-07-01 00:00:00

abstract：:In keeping with the stated goal of providing the surgical pathologist with tools to recognize abnormalities of the gastrointestinal (GI) tract due to drugs (AGIDS), in part II of this review we embark in a more organ-based description of AGIDS. Adequate space is given to the numerous adverse gastrointestinal effects o...

journal_title：International journal of surgical pathology

authors： De Petris G,Caldero SG,Chen L,Xiao SY,Dhungel BM,Spizcka AJ,Lam-Himlin D

更新日期：2014-05-01 00:00:00

abstract：:A 25-year-old patient presented with epigastric pain, which on gastric biopsy revealed the characteristic appearance of collagenous gastritis. There was a thick prominent subepithelial band that was confirmed to be collagen with a Masson's trichrome stain. There was associated Helicobacter pylori gastritis but no evid...

journal_title：International journal of surgical pathology

authors： Jain R,Chetty R

更新日期：2010-12-01 00:00:00

abstract：:Palisaded mammary-type myofibroblastoma is a rare variant of benign stromal spindle cell tumor whose histological features are well known. Nevertheless, no cytological features have been reported to date. In this article, we describe the cytological features of a case of palisaded mammary-type myofibroblastoma in whic...

journal_title：International journal of surgical pathology

authors： Fabbri VP,Damiani S,Baccarini P,Saguatti G,Cucchi MC,Foschini MP

更新日期：2017-04-01 00:00:00

abstract：:Mesonephric adenocarcinoma is a rare tumor type that is usually found in areas where the Wolffian duct was present during the fetal period. We report a case of mesonephric adenocarcinoma of the uterine corpus in a 66-year-old woman who presented with vaginal bleeding. Pelvic magnetic resonance imaging revealed a 2.7-c...

journal_title：International journal of surgical pathology

authors： Kim SS,Nam JH,Kim GE,Choi YD,Choi C,Park CS

更新日期：2016-04-01 00:00:00

abstract：:In this report, a case of metaplastic thymoma arising in a thymic cyst wall is discussed. The patient was a 61-year-old male whose chief complaint was sweating and chest pain. Imaging study revealed a mediastinal mass with right hemithoracic extension. He underwent surgical resection of the mass and remnants of the th...

journal_title：International journal of surgical pathology

authors： Poorabdollah M,Mehdizadeh E,Mohammadi F,Sabeti S

更新日期：2009-02-01 00:00:00

abstract：:A rare case of primary pleomorphic liposarcoma of the thigh with a myxoid component, in which divergent differentiation to a well-differentiated chondrosarcoma was focally present, is described. Presence of heterologous elements has mainly been recognized in the context of dedifferentiated liposarcomas. Few cases of b...

journal_title：International journal of surgical pathology

authors： Panoussopoulos D,Theodoropoulos G,Lazaris AC,Papadimitriou K

更新日期：2004-01-01 00:00:00

abstract：:Micrometastases in lymph nodes and blood may provide important prognostic information. In this study, cytokeratin 20 (CK20) positive cells in lymph nodes and circulating CK20 mRNA were studied using 57 paraffin-embedded lymph node specimens and blood from 24 patients with pN0 colorectal cancer (CRC), respectively. Res...

journal_title：International journal of surgical pathology

authors： Wong CS,Cheung MT,Ma BB,Pun Hui E,Chan AC,Chan CK,Lee KC,Cheuk W,Lam MY,Wong MC,Chan CM,Chan JK,Chan AT

更新日期：2008-04-01 00:00:00

abstract：:Ninety-eight consecutive surgical biopsies of oral mucosa from 96 patients were evaluated immunohistochemically with an anti-cytokeratin 20 (CK 20) anti-body to evidence Merkel cells (MC). Fifteen cases, showing the highest number of MC, were additionally studied with chromogranin A, S-100 protein, neuro filaments, ep...

journal_title：International journal of surgical pathology

authors： Righi A,Betts CM,Marchetti C,Marucci G,Montebugnoli L,Prati C,Eusebi LH,Muzzi L,Ragazzini T,Foschini MP

更新日期：2006-07-01 00:00:00

abstract：:Mixed squamous and glandular papilloma (mixed papilloma) of the lung has been reported in fewer than 25 cases in the English literature. Although it is known as a benign tumor, malignant transformation has been reported. Papillary cystic carcinoma is characterized by papillary and cystic growth patterns and has been r...

journal_title：International journal of surgical pathology

authors： An AR,Park SY,Kim JH,Chae KJ,Chung MJ

更新日期：2020-09-01 00:00:00

abstract：:We report a cytohistologic and immunohistochemical study of 2 cases of papillary thyroid carcinoma occurring in a thyroglossal duct cyst. The patients were a 21-year-old woman and a 48-year-old man. Needle aspiration cytology smears were consistent with papillary thyroid carcinoma. The Sistrunk procedure was done. Pap...

journal_title：International journal of surgical pathology

authors： Falconieri G,Della Libera D,Zanella M

更新日期：2001-01-01 00:00:00

abstract：:Metastases to cervical lymph nodes (LNs) are an important independent adverse indicator in the prognosis of oral squamous cell carcinoma (OSCC). An accurate evaluation of molecular patterns favoring the metastatic process can be helpful in predicting cases of OSCC with elevated probability of early or late metastases ...

journal_title：International journal of surgical pathology

authors： Foschini MP,Leonardi E,Eusebi LH,Farnedi A,Poli T,Tarsitano A,Cocchi R,Marchetti C,Gentile L,Sesenna E,Marucci G,Montebugnoli L

更新日期：2013-04-01 00:00:00

abstract：AIMS. GIARDIA:is sometimes missed by the pathologist, and we sought to determine how often this occurs at our institution-a large tertiary care center with a subspecialty gastrointestinal pathology service and what certain clinical and histologic clues can be used to flag cases with a higher likelihood of infection, ta...

journal_title：International journal of surgical pathology

authors： Shen MJ,Voltaggio L,Robertson S

更新日期：2020-08-10 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a rare entity that most commonly arises from the skin. Angiosarcoma (AS) is a rare malignancy with a predilection for elderly males, has endothelial differentiation and a notoriously poor prognosis despite aggressive therapy. Herein, we report an angiosarcoma colliding with a MCC, in a p...

journal_title：International journal of surgical pathology

authors： Hacking S,Chavaria H,Khan L,Das K

更新日期：2020-05-01 00:00:00

abstract：:A 16-year-old boy presented with a tumor located in fourth ventricle, which showed histological features of an ependymoma replete with perivascular pseudorosettes and true ependymal rosettes. Interestingly, many of the tumor cells exhibited abundant cytoplasm stuffed with a grayish brown pigment. Histochemical stains ...

journal_title：International journal of surgical pathology

authors： Malhotra A,Rao S,Santhoshkumar R,Muralidharan N,Mitra S,Shetty S

更新日期：2021-02-01 00:00:00

abstract：:Mucoepidermoid carcinoma (MEC) shows a wide morphologic spectrum, including epithelium with oncocytic or squamous metaplastic changes overlying a prominent cystic architecture, as well as tumor-associated lymphoid tissue. We illustrate a case of MEC of the parotid in a 17-year-old female, in which all these features o...

journal_title：International journal of surgical pathology

authors： Heatley N,Harrington KJ,Thway K

更新日期：2018-02-01 00:00:00

abstract：:Cells with a resemblance to Gaucher cells, sometimes called pseudo-Gaucher cells, are seen in the bone marrow of some patients with hematologic malignancy or anemia. These cells are derived from cells of the monocytic lineage but do not show the characteristic inclusions of true Gaucher cells when examined by electron...

journal_title：International journal of surgical pathology

authors： Stenzel P,Weeks DA

更新日期：2013-02-01 00:00:00

abstract：:Renal cell carcinoma (RCC) in children and young adults is rare and pathologically problematic. RCC can be either hereditary or sporadic and has a guarded prognosis because appropriate management has not been established. A case of RCC in an 11-year-old is reported. The clinical presentation was a right abdominal mass...

journal_title：International journal of surgical pathology

authors： Winarti NW,Argani P,De Marzo AM,Hicks J,Mulyadi K

更新日期：2008-01-01 00:00:00

abstract：:Warthin tumor is the second most common salivary gland neoplasm. It occurs more commonly in males than in females. Malignant transformation in Warthin tumor is a rare but well-recognized phenomenon; however, the development or presentation of lymphoma in a Warthin tumor is rare. An 80-year-old man presented with painl...

journal_title：International journal of surgical pathology

authors： Jawad H,McCarthy P,O'Leary G,Heffron CC

更新日期：2018-05-01 00:00:00

abstract：:Fibroadenoma and phyllodes tumors of the breast exhibit a continuum of pathologic features. We examined phyllodes tumors initially called fibroadenoma for features that may accurately classify the tumor as phyllodes tumor on the first biopsy specimen. The phyllodes tumors initially called fibroadenoma for features tha...

journal_title：International journal of surgical pathology

authors： Yohe S,Yeh IT

更新日期：2008-04-01 00:00:00