Detection of Merkel cell carcinoma polyomavirus in mucosal Merkel cell carcinoma.

abstract：:Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases at the ...

journal_title：International journal of surgical pathology

authors： Toll AD,Mitchell D,Yeo CJ,Hruban RH,Witkiewicz AK

更新日期：2011-12-01 00:00:00

abstract：:PEComas are mesenchymal neoplasms composed of perivascular epithelioid cells (PEC) and include a spectrum of tumors. PEComas and malignant melanoma share common morphological, immunohistochemical, and ultrastructural features, such as epithelioid cell morphology and melanocytic immunophenotype. Melanocytic markers com...

journal_title：International journal of surgical pathology

authors： Ferenczi K,Lastra RR,Farkas T,Elenitsas R,Xu X,Roberts S,Brooks JS,Zhang PJ

更新日期：2012-02-01 00:00:00

abstract：:Clear cell chondrosarcoma (CCCS) is a rare variant of conventional chondrosarcoma with low-grade malignant features that may be confused radiographically and histologically with chondroblastoma. We report a case of a 50-year-old female who presented with 6 months of left hip pain. Initial radiographs demonstrated an o...

journal_title：International journal of surgical pathology

authors： Kiefer RM,Wojcik J,Cooper K,Weber KL,Sebro R

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Acetylcholinesterase (AchE) histochemistry has been established as an accurate diagnostic tool for Hirschsprung's disease (HD). In addition, calretinin immunohistochemistry is also reported as a reliable and adjunctive method to diagnose HD. We investigated the diagnostic value of combined AchE histochemistr...

journal_title：International journal of surgical pathology

authors： Jeong H,Jung HR,Hwang I,Kwon SY,Choe M,Kang YN,Jung E,Kim SP

更新日期：2018-09-01 00:00:00

abstract：:Circulating tumor cells are rare in peripheral blood smears. We report the case of a patient with circulating breast carcinoma cells resembling circulating myeloid blasts and provide a brief review of the literature. Peripheral blood smears and a bone marrow aspirate were examined morphologically and by flow cytometry...

journal_title：International journal of surgical pathology

authors： Rowan DJ,Logunova V,van Tuinen P,Olteanu H,Peterson JF

更新日期：2017-02-01 00:00:00

abstract：:Primitive neuroepithelial differentiation in malignant peripheral nerve sheath tumors (MPNSTs) has been reported in children but is extremely rare in adults. The authors report the case of a 70-year-old woman who presented with swelling of the right leg of 1-month duration. Fine-needle aspiration cytology was suggesti...

journal_title：International journal of surgical pathology

authors： Anvikar AR,Kulkarni MP,Ramteerthakar NA,Gosavi AV,Sulhyan KR

更新日期：2012-10-01 00:00:00

abstract：:Colonic perineurioma has been depicted as characterized by a mucosal proliferation of monomorphic spindle perineurial cells leading to an evident separation, distortion, and entrapment of colonic crypts. The authors, however, believe that a sizable subset of the cases differ in that they display only a limited perineu...

journal_title：International journal of surgical pathology

authors： Groisman G,Amar M,Alona M

更新日期：2010-08-01 00:00:00

abstract：:The role and diagnostic efficacy of gene and protein products RB1, CDK4, CHMP2B, HSP90, and cPLA2G4A, all previously shown to be involved in tumor genesis and cell proliferation, were examined by immunohistochemical techniques in 32 cases of myxofibrosarcomas and 29 myxoid liposarcomas (all diagnosis had been confirme...

journal_title：International journal of surgical pathology

authors： Wang T,Goodman MA,McGough RL,Weiss KR,Rao UN

更新日期：2014-10-01 00:00:00

abstract：:To further study the characteristics of renal cell carcinoma (RCC) in young patients and better define their biological features, 46 RCCs of patients younger than 25 years were morphologically and immunohistochemically characterized with follow-up. Loss of heterozygosity (LOH) analysis of the von Hippel-Lindau (VHL) g...

journal_title：International journal of surgical pathology

authors： Rao Q,Chen JY,Wang JD,Ma HH,Zhou HB,Lu ZF,Zhou XJ

更新日期：2011-04-01 00:00:00

abstract：:Micrometastases in lymph nodes and blood may provide important prognostic information. In this study, cytokeratin 20 (CK20) positive cells in lymph nodes and circulating CK20 mRNA were studied using 57 paraffin-embedded lymph node specimens and blood from 24 patients with pN0 colorectal cancer (CRC), respectively. Res...

journal_title：International journal of surgical pathology

authors： Wong CS,Cheung MT,Ma BB,Pun Hui E,Chan AC,Chan CK,Lee KC,Cheuk W,Lam MY,Wong MC,Chan CM,Chan JK,Chan AT

更新日期：2008-04-01 00:00:00

abstract：:Simple melanosis of the bladder is an uncommon condition with fewer than 15 reported cases characterized by multifocal, diffuse melanin pigmentation of the urothelial mucosa. It is frequently associated with urinary incontinence or urgency. Histologically, melanin granules are present within urothelial cells or lamina...

journal_title：International journal of surgical pathology

authors： Talmon GA,Khan AU,Koerber RK,Johansson SL

更新日期：2010-12-01 00:00:00

abstract：:A cystic swelling in the parotid gland should lead to a differential diagnosis that includes benign cystic lesion of the gland, benign tumors that are frequently associated with cystic degeneration or entirely cystic de novo, or even a malignant neoplasm. The case presented is that of a cystic parotid swelling of 2 ye...

journal_title：International journal of surgical pathology

authors： Qannam A,Bello IO,Al-Kindi M,Al-Hindi M

更新日期：2013-04-01 00:00:00

abstract：:The authors describe a case of multifocal perivascular epithelioid cell tumor (PEComa) arising in the pelvis of a 39-year-old woman affected by tuberous sclerosis. The tumor presented in the form of multiple fascicular, focally cystic nodules involving the uterine corpus, both ovaries, and the omentum. Microscopically...

journal_title：International journal of surgical pathology

authors： Froio E,Piana S,Cavazza A,Valli R,Abrate M,Gardini G

更新日期：2008-10-01 00:00:00

abstract：:The role of histopathology for diagnosing celiac disease (CD) has been recently challenged. However, based in our experience with roughly 4,600 distal duodenal and jejunal biopsies in children it is apparent that appropriate biopsy site, handling, processing, and microscopic evaluation result in a consistent pattern o...

journal_title：International journal of surgical pathology

authors： Drut R,Rúa EC

更新日期：2001-10-01 00:00:00

abstract：:Intrasellar rhabdomyosarcoma is rare, and when arising in collusion with an unrelated entity, can present a diagnostic pitfall. We describe a case of a 56-year-old woman who presented with right eye ptosis and a pituitary mass, which was resected and diagnosed as atypical pituitary adenoma. Because of residual disease...

journal_title：International journal of surgical pathology

authors： Duncan VE,Nabors LB,Warren PP,Conry RM,Willey CD,Perry A,Riley KO,Hackney JR

更新日期：2016-12-01 00:00:00

abstract：:We present the first documented case of hemangioblastoma located in the left colon. A 75-year-old woman undergoing adjuvant chemotherapy for breast cancer experienced rectal bleeding. Colonoscopy revealed a roundish mass covered with normal mucosa in the sigmoid colon. Endoscopic ultrasound showed an isoechoic lesion ...

journal_title：International journal of surgical pathology

authors： Casadei Gardini A,Pieri F,Fusaroli P,Oboldi D,Passardi A,Monti M,Rosetti P,Calpona S,Valgiusti M,Ragazzini A,Amadori D,Frassineti GL

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Phyllodes tumors (PTs) of the breast are rare biphasic neoplasms and are classified as benign, borderline, or malignant. Many biological markers have been studied to discriminate between different grades of PTs. IMP3 is a member of the insulin-like growth factor II mRNA binding protein (IMP) family and is ex...

journal_title：International journal of surgical pathology

authors： Bellezza G,Prosperi E,Del Sordo R,Colella R,Rulli A,Sidoni A

更新日期：2016-02-01 00:00:00

abstract：:Cystic neoplasms of the pancreas are rare and often mistaken for pseudocyst by imaging studies and macroscopic examination. We describe an unusual tumor of the pancreas composed of a mural nodule of anaplastic carcinoma arising from a huge ductal adenocarcinoma undergoing cystic degeneration. The cyst measured 27 x 13...

journal_title：International journal of surgical pathology

authors： Lee LY,Hsu HL,Chen HM,Hsueh C

更新日期：2003-07-01 00:00:00

abstract：:We report a case of polymorphous hemangioendothelioma, a rare vascular neoplasm, arising in the liver of a 51-year-old woman. Microscopically, this neoplasm is characterized by a polymorphous blend of solid, primitive vascular and angiomatous areas in variable proportions. Polymorphous hemangioendothelioma is consider...

journal_title：International journal of surgical pathology

authors： El Hussein S,Omarzai Y

更新日期：2017-05-01 00:00:00

abstract：:Carcinomas in the breast with a predominantly clear cytoplasm are rare. In this article, we review the differential diagnosis of clear cell breast neoplasms and report a case of invasive lobular carcinoma with extensive clear cell morphology that was diagnosed as invasive ductal carcinoma, not otherwise specified, on ...

journal_title：International journal of surgical pathology

authors： Kavesh MH,Sanchez D,Asirvatham JR

更新日期：2020-04-01 00:00:00

abstract：:Rosai-Dorfman disease (RDD; sinus histiocytosis with massive lymphoadenopathy) is a rare, usually nodal self-limited disease. Sometimes nodal disease is coupled with extranodal localizations, in which case the disease can follow a protracted clinical course characterized by remissions and relapses and, exceptionally, ...

journal_title：International journal of surgical pathology

authors： Di Tommaso L,Rahal D,Bossi P,Roncalli M

更新日期：2010-12-01 00:00:00

abstract：:In this article, we report the case of a 40-year-old woman with a sessile polyp of the rectosigmoid junction that underwent endoscopic resection. The resected specimen showed spindle cell proliferation with eosinophilic cytoplasm between mucosal crypts, mimicking mucosal prolapse syndrome. However, these were immunohi...

journal_title：International journal of surgical pathology

authors： Hashimoto H,Usui G,Sakai E,Ohata K,Morikawa T

更新日期：2019-08-01 00:00:00

abstract：:Primary pulmonary mucin-rich lesions with abundant goblet cells growing within alveolar spaces are either classified as mucinous adenocarcinoma (previously called mucinous bronchioloalveolar carcinoma) or colloid carcinoma. Some of these lesions display a morphologic pattern characterized by paucicellular discontinuou...

journal_title：International journal of surgical pathology

authors： Jessurun J

更新日期：2015-05-01 00:00:00

abstract：:Spitz tumors are a group of melanocytic neoplasms with distinct morphological features that tend to affect young individuals. Distinguishing benign from malignant Spitz tumors can be challenging, but cytogenetic and molecular tests have contributed to improvements in diagnostic accuracy. Spitz tumors harbor diverse ge...

journal_title：International journal of surgical pathology

authors： Kiuru M,Jungbluth A,Kutzner H,Wiesner T,Busam KJ

更新日期：2016-05-01 00:00:00

abstract：:Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a rare tumor-like lesion with unclear pathogenesis. Collision lesions of CAPNONs with neoplasms are occasionally reported. In this article, we report the first case of collision lesions between CAPNON and rheumatoid nodules (RNs) in a patient with systemic lupus er...

journal_title：International journal of surgical pathology

authors： Lu JQ,Popovic S,Provias J,Cenic A

更新日期：2020-07-15 00:00:00

abstract：BACKGROUND:To avoid diagnostic errors such as missed diagnosis and errors in staging tumors due to inadequate tissue sampling, pathologists submit additional sections (AS). OBJECTIVE:This study assessed frequency, diagnostic yield, distribution, and cost of AS. METHOD:Among 1542 AS cases, we calculated mean AS per ca...

journal_title：International journal of surgical pathology

authors： Hamza A,Alrajjal A,Edens J,Khawar S,Khurram MS,Szpunar S,Bonnett M

更新日期：2018-08-01 00:00:00

abstract：:Appendiceal pneumatosis is rare, reported either in the context of acute appendicitis or enterocolitis. Here, we report the case of an elderly adult in whom the acute appendicitis was associated with pneumatosis and occurred in the context of a malformed appendix with pathogenic organism remnants. A 72-year-old man pr...

journal_title：International journal of surgical pathology

authors： Handra-Luca A,Bisseret D,Dragoescu E

更新日期：2016-02-01 00:00:00

abstract：:We report our experience with Chromogenic in Situ Hybridization (CISH) for the evaluation of HER2 amplification on 55 cases of formalin-fixed, paraffin-embedded invasive breast carcinomas of different histology. All the results were corrected for chromosome 17 aneusomy and compared with immunohistochemistry (IHC); a s...

journal_title：International journal of surgical pathology

authors： Li-Ning-T E,Ronchetti R,Torres-Cabala C,Merino MJ

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:The phenomenon of vanishing carcinomas, first described in context of prostatic carcinomas, has been documented in endometrial carcinomas as well. METHODS:The archives of the department were searched for case files of endometrial carcinoma diagnosed on endometrial curetting/biopsy but which did not reveal a...

journal_title：International journal of surgical pathology

authors： Bharani V,Rai B,Rajwanshi A,Gupta N,Dey P,Kalra J,Suri V,Srinivasan R

更新日期：2019-02-01 00:00:00

abstract：:The majority of alveolar RMSs have t(2;13)(q35;q14) or (1:13)(p36;q14),which generate PAX3/7 -FKHR fusion genes. Here, the authors detected the PAX3/7-FKHR fusion transcripts in 17 formalin-fixed, paraffin-embedded RMSs and 26 other SRCTs using one-step RT-PCR. PAX3 -FKHR and PAX7-FKHR transcripts were positive in 4/8...

journal_title：International journal of surgical pathology

authors： Chang B,Pang LJ,Qi Y,Liu CX,Cao Y,Li HA,Hu WH,Jiang JF,Zhang WJ,Li F

更新日期：2009-02-01 00:00:00