Cancer stem cells--the current status of an old concept: literature review and clinical approaches.

abstract：:The aim of this study is to describe the ultrastructural changes of the egg apparatus associated with fertilisation of the natural tetraploid Trifolium pratense. The pollen tube enters one of the synergids through the filliform apparatus from the micropyle. Before the entry of the pollen tube into the embryo sac, one ...

journal_title：Biological research

authors： Buyukkartal HN

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:IcarisideII (ICAII) could promote the differentiation of adipose tissue-derived stem cells (ADSCs) to Schwann cells (SCs), leading to improvement of erectile function (EF) and providing a realistic therapeutic option for the treatment of erectile dysfunction (ED). However, the underlying molecular mechanisms...

journal_title：Biological research

authors： Ge P,Guo Y,Shen J

更新日期：2019-10-03 00:00:00

abstract：:In this article, we focus on the fundamental role of vitamin C transporters for the normal delivery of vitamin C to germ cells in the adluminal compartment of seminiferous tubules. We argue that the redox status within spermatozoa or in semen is partly responsible for the etiology of infertility. In this context, anti...

journal_title：Biological research

authors： Angulo C,Maldonado R,Pulgar E,Mancilla H,Córdova A,Villarroel F,Castro MA,Concha II

更新日期：2011-01-01 00:00:00

abstract：:The historical, lexical and conceptual issues embedded in stem cell biology are reviewed from technical, ethical, philosophical, judicial, clinical, economic and biopolitical perspectives. The mechanisms assigning the simultaneous capacity to self-renew and to differentiate to stem cells (immortal template DNA and asy...

journal_title：Biological research

authors： Monti M,Perotti C,Del Fante C,Cervio M,Redi CA,Fondazione IRCCS Policlinico San Matteo, Pavia (Italia).

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is highly aggressive with poor prognosis. Long non-coding RNAs (lncRNAs), a group of non-coding RNAs, play important roles in the progression of PDAC. This study aimed to investigate the potential involvement of lncRNA CCAT2 in PDAC tumorigenesis. METHODS:Expression o...

journal_title：Biological research

authors： Cai Y,Li X,Shen P,Zhang D

更新日期：2018-01-03 00:00:00

abstract：:Transducin serves as a mediator between the receptor protein, rhodopsin, and the effector protein, cGMP phosphodiesterase, in the visual process. Transducin is a protein composed of three polypeptides: T alpha, T beta, and T gamma, and acts as two functional units, the alpha-subunit and the beta gamma-complex. In the ...

journal_title：Biological research

authors： Bubis J

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Ubiquitin specific peptidase 39 (USP39), an essential factor in the assembly of the mature spliceosome complex, has an aberrant expression in several cancer. However, its function and the corresponding mechanism on human osteosarcoma has not been fully explored yet. METHODS:The mRNA and DNA copies of USP39 ...

journal_title：Biological research

authors： Gan Z,Han K,Lin S,Hu H,Shen Z,Min D

更新日期：2017-04-12 00:00:00

abstract：BACKGROUND:Conjunctival filtering bleb scar formation is the main reason for the failure of glaucoma filtration surgery. Cytoglobin (Cygb) has been reported to play an important role in extracellular matrix (ECM) remodeling, fibrosis and tissue damage repairing. This study aimed to investigate the role of Cygb in anti-...

journal_title：Biological research

authors： Wei H,Lin L,Zhang X,Feng Z,Wang Y,You Y,Wang X,Hou Y

更新日期：2019-04-16 00:00:00

abstract：:The neuropeptide oxytocin (OXT) is a key factor in the initiation and regulation of sociosexual behavior. The present study analyzes the effects of cohabitation and social challenge on plasma OXT concentration rates in guinea pig pairs in relation to male sociosexual behavior. The cohabitation phase lasted 3 days. On ...

journal_title：Biological research

authors： Wallner B,Dittami J,Machatschke I

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The study was conducted to evaluate the in vitro thrombolytic activity, and in vivo analgesic, anti-inflammatory and antipyretic potentials of different hydrocarbon soluble extracts of Litsea glutinosa leaves for the first time widely used in the folkloric treatments in Bangladesh. This work aimed to create ...

journal_title：Biological research

authors： Bhowmick R,Sarwar MS,Dewan SM,Das A,Das B,Uddin MM,Islam MS,Islam MS

更新日期：2014-10-29 00:00:00

abstract：:Changes in the redox state of the intracellular ryanodine receptor/Ca2+ release channels of skeletal and cardiac muscle or brain cortex neurons affect their activity. In particular, agents that oxidize or alkylate free SH residues of the channel protein strongly enhance Ca(2+)-induced Ca2+ release, whereas reducing ag...

journal_title：Biological research

authors： Hidalgo C,Bull R,Behrens MI,Donoso P

更新日期：2004-01-01 00:00:00

abstract：:The radiobiocomplexes labeled with technetium-99m (Tc-99m) have been widely used in nuclear medicine in single photon emission computed tomography and in basic research. The aim of this study was to assess the influence of a Nectandra membranacea extract on the bioavailability of the sodium pertechnetate (Na(99m)TcO(4...

journal_title：Biological research

authors： Moreno SR,Arnobio A,De Carvalho JJ,Nascimento L,Oliveira Timoteo M,Olej B,Rocha EK,Pereira M,Bernardo-Filho M,Caldas LQ

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The Hawthorn (Crateagus sp.) mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn species grown in E...

journal_title：Biological research

authors： Gundogdu M,Ozrenk K,Ercisli S,Kan T,Kodad O,Hegedus A

更新日期：2014-05-30 00:00:00

abstract：:Vasopressin and bradykinin are two of the most important peptides in regulating vascular tone, water, and ionic balance in the body, and thus they play a key role in controlling blood pressure. In addition to being a potent vasoconstrictor, Vasopressin also has an antidiuretic activity in the kidney, whereas kinins re...

journal_title：Biological research

authors： Gonzalez CB,Figueroa CD

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The Tridax procumbens flavonoids (TPF), are well known for their medicinal properties among local natives. The TPF are traditionally used for dropsy, anaemia, arthritis, gout, asthma, ulcer, piles, and urinary problems. It also used in treating gastric problems, body pain, and rheumatic pains of joints. The ...

journal_title：Biological research

authors： Al Mamun MA,Islam K,Alam MJ,Khatun A,Alam MM,Al-Bari MA,Alam MJ

更新日期：2015-09-12 00:00:00

abstract：BACKGROUND:Prognosis remains one of most crucial determinants of gastric cancer (GC) treatment, but current methods do not predict prognosis accurately. Identification of additional biomarkers is urgently required to identify patients at risk of poor prognoses. METHODS:Tissue microarrays were used to measure expressio...

journal_title：Biological research

authors： Li W,Chen Y,Sun X,Yang J,Zhang DY,Wang D,Suo J

更新日期：2019-08-09 00:00:00

abstract：BACKGROUND:Zinc finger RNA binding protein (ZFR) is involved in the regulation of growth and cancer development. However, little is known about ZFR function in pancreatic cancer. METHODS:Herein, to investigate whether ZFR is involved in tumor growth, Oncomine microarray data was firstly used to evaluate ZFR gene expre...

journal_title：Biological research

authors： Zhao X,Chen M,Tan J

更新日期：2016-05-13 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is secondary to loss-of-function mutations in the dystrophin gene. The causes underlying the progression of DMD, differential muscle involvement, and the discrepancies in phenotypes among species with the same genetic defect are not understood. The mdx mouse, an animal model with dyst...

journal_title：Biological research

authors： Fadic R

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:CCL2 was up-regulated in neurons and involved in microglia activation and neurological decline in mice suffering from hepatic encephalopathy (HE). However, no data exist concerning the effect of neuron-derived CCL2 on microglia activation in vitro. METHODS:The rats were pretreated with CCL2 receptor inhibit...

journal_title：Biological research

authors： Zhang L,Tan J,Jiang X,Qian W,Yang T,Sun X,Chen Z,Zhu Q

更新日期：2017-09-04 00:00:00

abstract：:Object recognition memory allows discrimination between novel and familiar objects. This kind of memory consists of two components: recollection, which depends on the hippocampus, and familiarity, which depends on the perirhinal cortex (Pcx). The importance of brain-derived neurotrophic factor (BDNF) for recognition m...

journal_title：Biological research

authors： Muñoz PC,Aspé MA,Contreras LS,Palacios AG

更新日期：2010-01-01 00:00:00

abstract：:Exposure to arsenic via drinking water is considered as a worldwide problem. Studies have shown that arsenic exposure during pregnancy affects embryogenesis and offspring development in rats and mice. Zinc as a micronutrient regulates many physiological functions, including an antioxidative role under various toxic co...

journal_title：Biological research

authors： Ahmad M,Wadaa MA,Farooq M,Daghestani MH,Sami AS

更新日期：2013-01-01 00:00:00

abstract：:Allium cepa L. meristems were used as a plant model to study the p53-independent control of S and G2 phases by checkpoint pathways, in eukaryotic cells. Checkpoint blocks were induced at early and mid S by hydroxyurea. After their spontaneous override, cells became accumulated in G2-prophase, giving rise later on to a...

journal_title：Biological research

authors： Pelayo HR,Pincheira J,Giménez-Abián JF,Clarke DJ,de la Torre C

更新日期：2003-01-01 00:00:00

abstract：:The present work was intended to evaluate the preparation of antigens, as well as the production and characterization of anti cAMP and cGMP antibodies. Such antibodies were obtained from rabbits, and we used 2'O-succinyl cyclic nucleotide derivate, conjugated with human serum albumin, as antigen. The characterization ...

journal_title：Biological research

authors： Defagot C,Zubin P

更新日期：1994-01-01 00:00:00

abstract：:Cyanobacteria display a large diversity of cellular forms ranging from unicellular to complex multicellular filaments or aggregates. Species in the group present a wide range of metabolic characteristics including the fixation of atmospheric nitrogen, resistance to extreme environments, production of hydrogen, seconda...

journal_title：Biological research

authors： Stucken K,Koch R,Dagan T

更新日期：2013-01-01 00:00:00

abstract：:Many motor skills, once acquired, are stored over a long time period, probably sustained by permanent neuronal changes. Thus, in this paper we have investigated with quantitative stereology the generation and persistence of neuronal density changes in primary motor cortex (MI) following motor skill learning (skilled r...

journal_title：Biological research

authors： Morales P

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The role of interleukin family in colon cancer remained controversial. The purpose of this study was to investigate the association between interleukin family and colon cancer progression through bioinformatics methods and to validate such association in clinical patients. METHODS:A total of 15 differential...

journal_title：Biological research

authors： Wei X,Zhang Y,Yang Z,Sha Y,Pan Y,Chen Y,Cai L

更新日期：2020-05-07 00:00:00

abstract：:Oxidant/antioxidant imbalance has been reported in some infectious diseases, including community-acquired pneumonia (CAP). The aim was to assess the antioxidant status in adults with CAP and its relationship with clinical severity at admission. Fifty-nine patients with CAP were enrolled and categorized at admission by...

journal_title：Biological research

authors： Castillo RL,Carrasco RA,Alvarez PI,Ruiz M,Luchsinger V,Zunino E,Martínez MA,Avendaño LF

更新日期：2013-01-01 00:00:00

abstract：:Unilateral brain damage which includes the hippocampus leads to memory impairments consistent with hemispheric specialization on the same side. Damage to the corpus callosum, the major connecting pathway between the left and right hemispheres, also leads to memory impairments. This suggests both hemispheric specializa...

journal_title：Biological research

authors： Zaidel DW

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Psoriasis is a common chronic inflammatory skin disease. Keratinocytes hyperproliferation and excessive inflammatory response contribute to psoriasis pathogenesis. The agents able to attenuate keratinocytes hyperproliferation and excessive inflammatory response are considered to be potentially useful for pso...

journal_title：Biological research

authors： Gao J,Chen F,Fang H,Mi J,Qi Q,Yang M

更新日期：2020-10-20 00:00:00

abstract：:Although several histone variants have been studied in both animal and plant organisms, little is known about their distribution during processes that involve alterations in chromatin function, such as differentiation, dedifferentiation and hormone treatment. In this study we evaluated the ratio of each histone varian...

journal_title：Biological research

authors： Alatzas A,Foundouli A

更新日期：2009-01-01 00:00:00