Abstract：
:Although several histone variants have been studied in both animal and plant organisms, little is known about their distribution during processes that involve alterations in chromatin function, such as differentiation, dedifferentiation and hormone treatment. In this study we evaluated the ratio of each histone variant in each of the four core histone classes in the three developmental zones of maize (Zea mays L.) root and in callus cultures derived from them, in order to define possible alterations either during plant cell differentiation or dedifferentiation. We also evaluated core histone variant ratios in the developmental zones of roots treated with auxin and gibberellin in order to examine the effects of exogenously applied plant hormones to histone variant distribution. Finally, immunohistochemical detection was used to identify the root tissues containing modified forms of core histones and correlates them with the physiological status of the plant cells. According to the results presented in this study, histone variant ratios are altered in all the cases examined, i.e. in the developmental zones of maize root, in callus cultures derived from them and in the developmental zones of roots treated either with auxin or gibberellin. We propose that the alterations in linker histone variant ratios are correlated with plant cell differentiation and physiological status in each case.
journal_name
Biol Resjournal_title
Biological researchauthors
Alatzas A,Foundouli Adoi
/S0716-97602009000400006subject
Has Abstractpub_date
2009-01-01 00:00:00pages
445-60issue
4eissn
0716-9760issn
0717-6287pii
S0716-97602009000400006journal_volume
42pub_type
杂志文章abstract：BACKGROUND:Accumulating studies have demonstrated that high-mobility group A2 (HMGA2), an oncofetal protein, plays a role in tumor development and progression. However, the molecular role of HMGA2 in ovarian carcinoma is yet to be established. MicroRNAs (miRNAs), a group of small noncoding RNAs, negatively regulate gen...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-018-0199-y
更新日期：2018-11-24 00:00:00
abstract：:The development of plant transformation in the mid-1980s and of many new tools for cell biology, molecular genetics, and biochemistry has resulted in enormous progress in plant biology in the past decade. With the completion of the genome sequence of Arabidopsis thaliana just around the corner, we can expect even fast...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：:In this article, we focus on the fundamental role of vitamin C transporters for the normal delivery of vitamin C to germ cells in the adluminal compartment of seminiferous tubules. We argue that the redox status within spermatozoa or in semen is partly responsible for the etiology of infertility. In this context, anti...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602011000200009
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Ubiquitin specific peptidase 39 (USP39), an essential factor in the assembly of the mature spliceosome complex, has an aberrant expression in several cancer. However, its function and the corresponding mechanism on human osteosarcoma has not been fully explored yet. METHODS:The mRNA and DNA copies of USP39 ...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-017-0121-z
更新日期：2017-04-12 00:00:00
abstract：BACKGROUND:Osteoarthritis (OA) is a common arthritic disease and multifactorial whole-joint disease. Interactions of chemokines and OA is inadequately documented. RESULTS:In vivo and in vitro studies were conducted to investigate monocyte chemoattractant protein 1 (MCP-1) and receptor chemokine (C-C motif) receptor 2 ...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-015-0057-0
更新日期：2015-11-17 00:00:00
abstract：:Although evidence is accumulating that prenatal testosterone (T) compromises reproductive function in the female, the effects of excess T in utero on the postnatal development of male reproductive function has not been studied. The aim of this study was to assess the influence of prenatal T excess on age-related chang...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602007000400007
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:Psoralen is a coumarin-like and coumarin-related benzofuran glycoside, which is a commonly used traditional Chinese medicine to treat patients with kidney and spleen-yang deficiency symptom. Psoralen has been reported to show estrogen-like activity, antioxidant activity, osteoblastic proliferation accelerati...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-019-0241-8
更新日期：2019-07-05 00:00:00
abstract：:Thymulin is a well-characterized thymic hormone that exists as a nonapeptide coupled to equimolar amounts of Zn2+. Thymulin is known to have multiple biological roles, including T cell differentiation, immune regulation, and analgesic functions. It has been shown that thymulin is produced by the reticulo-epithelial ce...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602010000300005
更新日期：2010-01-01 00:00:00
abstract：:Transducin serves as a mediator between the receptor protein, rhodopsin, and the effector protein, cGMP phosphodiesterase, in the visual process. Transducin is a protein composed of three polypeptides: T alpha, T beta, and T gamma, and acts as two functional units, the alpha-subunit and the beta gamma-complex. In the ...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:This study examined the effects of estrogen supplementation on markers of neutrophil infiltration and damage in skeletal muscle of rats following ischemia. Male and female gonad-intact rats, with or without 14 days of estrogen supplementation were subjected to two hours of hind-limb ischemia and sacrificed at 24, 48 o...
journal_title：Biological research
pub_type： 杂志文章
doi：10.4067/s0716-97602005000200011
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:α-Farnesene is a volatile sesquiterpene synthesized by the plant mevalonate (MVA) pathway through the action of α-farnesene synthase. The α-farnesene synthase 1 (MdAFS1) gene was isolated from apple peel (var. white winter pearmain), and transformed into tobacco (Nicotiana tabacum NC89). The transgenic plant...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-016-0088-1
更新日期：2016-07-02 00:00:00
abstract：BACKGROUND:Impaired wound healing is a complication of diabetes and a serious problem in clinical practice. We previously found that whey protein (WP) was able to regulate wound healing normally in streptozotocin (STZ)-diabetic models. This subsequent study was designed to assess the effect of WP on heat shock protein-...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-015-0044-5
更新日期：2015-10-01 00:00:00
abstract：:After the progress made during the genomics era, bioinformatics was tasked with supporting the flow of information generated by nanobiotechnology efforts. This challenge requires adapting classical bioinformatic and computational chemistry tools to store, standardize, analyze, and visualize nanobiotechnological inform...
journal_title：Biological research
pub_type： 杂志文章
doi：10.4067/S0716-97602011000100006
更新日期：2011-01-01 00:00:00
abstract：:The aim of this study is to describe the ultrastructural changes of the egg apparatus associated with fertilisation of the natural tetraploid Trifolium pratense. The pollen tube enters one of the synergids through the filliform apparatus from the micropyle. Before the entry of the pollen tube into the embryo sac, one ...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602009000100003
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:The Hawthorn (Crateagus sp.) mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn species grown in E...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/0717-6287-47-21
更新日期：2014-05-30 00:00:00
abstract：:Tumor growth is the result of combined cell proliferation overwhelming cell death and neoangiogenesis. This report shows CAM angiogenesis promoted by TA3 tumor supernatant with or without low dosis of betamethasone (Minimal antiangiogenic concentration: beta-MAAC). Methylcellulose discs instilled with 10 microliters o...
journal_title：Biological research
pub_type： 杂志文章
doi：10.4067/s0716-97602001000300010
更新日期：2001-01-01 00:00:00
abstract：:Bovine median eminence contains a factor difference from gonadotropin-releasing hormone (GnRH) than increases basal luteinizing hormone (LH) secretion and potentiates GnRH-stimulated LH release. We compared the effect of hypothalamic neuropeptides on basal and GnRH-stimulated LH secretion using rat pituitary cells und...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:Tear desiccation on a glass surface followed by transmitted-light microscopy has served as diagnostic test for dry eye. Four distinctive morphological domains (zones I, II, III and transition band) have been recently recognized in tear microdesiccates. Physicochemical dissimilarities among those domains hamp...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-016-0089-0
更新日期：2016-06-03 00:00:00
abstract：:Exposure to arsenic via drinking water is considered as a worldwide problem. Studies have shown that arsenic exposure during pregnancy affects embryogenesis and offspring development in rats and mice. Zinc as a micronutrient regulates many physiological functions, including an antioxidative role under various toxic co...
journal_title：Biological research
pub_type： 杂志文章
doi：10.4067/S0716-97602013000200003
更新日期：2013-01-01 00:00:00
abstract：:In the last few decades, several works on event related potentials (ERPs hereafter) during sleep have been reported. In spite of numerous studies, clear methodological rules for this kind of study are often missing, making it difficult to valorize the scope of these results. We propose here a description of methodolog...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602008000300004
更新日期：2008-01-01 00:00:00
abstract：:Loss of Imprinting (LOI) of IGF2 and over-expressed IGF2 are associated with tumorigenesis. Our previous epidemiological study found a relatively high frequency of IGF2 LOI in healthy mid-gestation pregnant women. The aim of this study is to determine whether the expression of IGF2 is associated with its imprinting st...
journal_title：Biological research
pub_type： 杂志文章
doi：10.4067/S0716-97602012000400004
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Papillary thyroid cancer (PTC) is the most common malignancy of all thyroid cancers. LncRNA LINC00460 has been proved to play roles in the oncogenesis and progression of various tumors, including papillary thyroid cancer. However, the potential molecular mechanism of LINC00460 in PTC is poorly investigated. ...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-019-0269-9
更新日期：2019-12-23 00:00:00
abstract：:Prolactin (PRL) is a pituitary hormone that plays important roles in mammalian reproductive physiology, specially lactation. The regulation of PRL secretion shows important species differences. To study PRL regulation in a subhuman primate, the Cebus apella, we developed an heterologous radioimmunoassay using an antib...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:Treatment of tumor-bearing mice with LD12.5 values of iodoacetate; IAA (1.84 mg/100 g b.w.) and/or dimethylsulphoxide; DMSO (350 mg/100 g b.w.) significantly increased the cumulative mean survival time and percentage of survivors and reduced the mean tumor weight, compared to tumor-bearing controls, however, a more pr...
journal_title：Biological research
pub_type： 杂志文章
doi：10.4067/s0716-97602003000200015
更新日期：2003-01-01 00:00:00
abstract：:The ascorbate-glutathione (ASC-GSH) cycle has an important role in defensive processes against oxidative damage generated by drought stress. In this study, the changes that take place in apoplastic and symplastic ASC-GSH cycle enzymes of the leaf and petiole were investigated under drought stress causing leaf rolling ...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602009000300006
更新日期：2009-01-01 00:00:00
abstract：:By using the fluorescent Ca2+ indicator fura 2, submicromolar levels of intracellular Ca2+ have been detected in Trypanosoma cruzi different stages. The intracellular transport mechanisms involved in maintaining Ca2+ homeostasis in T. cruzi have been characterized by measuring Ca2+ transport in digitonin-permeabilized...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Control of smooth muscle is vital for health. The major route to contraction is a rise in intracellular [Ca2+], determined by the entry and efflux of Ca2+ and release and re-uptake into the sarcoplasmic reticulum (SR). We review these processes in myometrium, to better understand excitation-contraction coupling and de...
journal_title：Biological research
pub_type： 杂志文章
doi：10.4067/s0716-97602004000400017
更新日期：2004-01-01 00:00:00
abstract：:Oxidative stress occurs early in the progression of Alzheimer disease, significantly before the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. In the first stage of development of the disease, amyloid-beta deposition and hyperphosphorylated tau function as compensatory responses a...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：10.4067/s0716-97602006000100002
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:The role of interleukin family in colon cancer remained controversial. The purpose of this study was to investigate the association between interleukin family and colon cancer progression through bioinformatics methods and to validate such association in clinical patients. METHODS:A total of 15 differential...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-020-00287-2
更新日期：2020-05-07 00:00:00
abstract：:X-Ray diffraction is the only method currently available for the determination of the detailed three-dimensional structure of macromolecules. In this article, the principles behind the use of X-ray crystallography in the study of protein structure are presented. The results obtained in its application to several enzym...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：
更新日期：1996-01-01 00:00:00
