CCAT2 is an oncogenic long non-coding RNA in pancreatic ductal adenocarcinoma.

abstract：:Oxidative stress occurs early in the progression of Alzheimer disease, significantly before the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. In the first stage of development of the disease, amyloid-beta deposition and hyperphosphorylated tau function as compensatory responses a...

journal_title：Biological research

authors： Moreira PI,Zhu X,Liu Q,Honda K,Siedlak SL,Harris PL,Smith MA,Perry G

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:IcarisideII (ICAII) could promote the differentiation of adipose tissue-derived stem cells (ADSCs) to Schwann cells (SCs), leading to improvement of erectile function (EF) and providing a realistic therapeutic option for the treatment of erectile dysfunction (ED). However, the underlying molecular mechanisms...

journal_title：Biological research

authors： Ge P,Guo Y,Shen J

更新日期：2019-10-03 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is a common arthritic disease and multifactorial whole-joint disease. Interactions of chemokines and OA is inadequately documented. RESULTS:In vivo and in vitro studies were conducted to investigate monocyte chemoattractant protein 1 (MCP-1) and receptor chemokine (C-C motif) receptor 2 ...

journal_title：Biological research

authors： Xu YK,Ke Y,Wang B,Lin JH

更新日期：2015-11-17 00:00:00

abstract：:The hypothesis that the vacation-study-expectancy scholar regime produces most of the monthly rhythm of the age at menarche (AaM) was tested. Studies on monthly menarche incidence (MI) refuted climatic factors as a main factor in this rhythm, and indicated that the main factor of this rhythm is the succession of expec...

journal_title：Biological research

authors： Valenzuela CY

更新日期：2013-01-01 00:00:00

abstract：:Cyanobacteria display a large diversity of cellular forms ranging from unicellular to complex multicellular filaments or aggregates. Species in the group present a wide range of metabolic characteristics including the fixation of atmospheric nitrogen, resistance to extreme environments, production of hydrogen, seconda...

journal_title：Biological research

authors： Stucken K,Koch R,Dagan T

更新日期：2013-01-01 00:00:00

abstract：:Peroxisomes are thought to be formed by division of pre-existing peroxisomes after the import of newly synthesized proteins. However, it has been recently suggested that the endoplasmic reticulum (ER) provides an alternative de novo mechanism for peroxisome biogenesis in some cells. To test a possible role of the ER-G...

journal_title：Biological research

authors： Toro A,Arredondo C,Córdova G,Araya C,Palacios JL,Venegas A,Morita M,Imanaka T,Santos MJ

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:miR-214 was demonstrated to be upregulated in models of renal disease and promoted fibrosis in renal injury independent of TGF-β signaling in vivo. However, the detailed role of miR-214 in acute kidney injury (AKI) and its underlying mechanism are still largely unknown. METHODS:In this study, an I/R-induced...

journal_title：Biological research

authors： Zhu X,Li W,Li H

更新日期：2018-09-04 00:00:00

abstract：:Red blood cell carbonic anhydrase (CA) activity has not been studied in high altitude natives. Because CA is an intraerythocytic enzyme and high altitude natives are polycythemic, it is important to know if the activity of CA per red cell volume is different from that of their sea level counterparts. Blood was collect...

journal_title：Biological research

authors： Gamboa J,Caceda R,Gamboa A,Monge-C C

更新日期：2000-01-01 00:00:00

abstract：:The expression of the acetyl xylan esterase II (axeII) gene from Penicillium purpurogenum is repressed by glucose and induced by xylan, as well as to a small degree by xylose and xylitol. This gene is expressed at neutral pH, but not under alkaline or acidic conditions, in agreement with previous findings for other xy...

journal_title：Biological research

authors： Chávez R,Schachter K,Navarro C,Peirano A,Bull P,Eyzaguirre J

更新日期：2004-01-01 00:00:00

abstract：:The aim of this study was to investigate the in vitro cytotoxic activity of total extract of MeOH (70%) and partition fractions of hexan, chloroform (CHCL3), ethylacetate (EtOAc) and MeOH-H2O of brown algae species (Sargassum swartzii, Cystoseira myrica, Colpomenia sinuosa) found in the Persian Gulf against in differe...

journal_title：Biological research

authors： Khanavi M,Nabavi M,Sadati N,Shams Ardekani M,Sohrabipour J,Nabavi SM,Ghaeli P,Ostad SN

更新日期：2010-01-01 00:00:00

abstract：:Tumor growth is the result of combined cell proliferation overwhelming cell death and neoangiogenesis. This report shows CAM angiogenesis promoted by TA3 tumor supernatant with or without low dosis of betamethasone (Minimal antiangiogenic concentration: beta-MAAC). Methylcellulose discs instilled with 10 microliters o...

journal_title：Biological research

authors： Lemus D,Dabancens A,Illanes J,Fuenzalida M,Guerrero A,López C

更新日期：2001-01-01 00:00:00

abstract：:Osteoporosis is a common metabolic bone disease, influenced by genetic and environmental factors, that increases bone fragility and fracture risk and, therefore, has a serious adverse effect on the quality of life of patients. However, epigenetic mechanisms involved in the development of osteoporosis remain unclear. T...

journal_title：Biological research

authors： Yang Y,Yujiao W,Fang W,Linhui Y,Ziqi G,Zhichen W,Zirui W,Shengwang W

更新日期：2020-09-16 00:00:00

abstract：:Despite the fact that the concept of sheet-flow in the pulmonary microcirculation of mammals was introduced more than three decades ago, the capillary circulatory model still prevails in the physiological literature. Since cardiac output is identical in the systemic and in pulmonary circulations, it is noteworthy that...

journal_title：Biological research

authors： Günther B,Morgado E,Cociña M

更新日期：2005-01-01 00:00:00

abstract：:As regards their morphology and biology, tumours consist of heterogeneous cell populations. The cancer stem cell (CSC) hypothesis assumes that a tumour is hierarchically organized and not all of the cells are equally capable of generating descendants, similarly to normal tissue. The only cells being able to self-renew...

journal_title：Biological research

authors： Fulawka L,Donizy P,Halon A

更新日期：2014-12-10 00:00:00

abstract：BACKGROUND:Papillary thyroid cancer (PTC) is the most common malignancy of all thyroid cancers. LncRNA LINC00460 has been proved to play roles in the oncogenesis and progression of various tumors, including papillary thyroid cancer. However, the potential molecular mechanism of LINC00460 in PTC is poorly investigated. ...

journal_title：Biological research

authors： Li G,Kong Q

更新日期：2019-12-23 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is secondary to loss-of-function mutations in the dystrophin gene. The causes underlying the progression of DMD, differential muscle involvement, and the discrepancies in phenotypes among species with the same genetic defect are not understood. The mdx mouse, an animal model with dyst...

journal_title：Biological research

authors： Fadic R

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The Hawthorn (Crateagus sp.) mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn species grown in E...

journal_title：Biological research

authors： Gundogdu M,Ozrenk K,Ercisli S,Kan T,Kodad O,Hegedus A

更新日期：2014-05-30 00:00:00

abstract：:A peptide from hindguts of the Triatoma infestans, the hematophagous Chagas' insect vector, activates adenylyl cyclase activity in Trypanosoma cruzi epimastigote membranes and stimulates the in vitro differentiation of epimastigotes (proliferative and non-infectious forms) to metacyclic trypomastigotes (non-proliferat...

journal_title：Biological research

authors： Fraidenraich D,Peña C,Isola EL,Lammel EM,Coso O,Añel AD,Baralle F,Torres HN,Flawia MM

更新日期：1993-01-01 00:00:00

abstract：:Hepcidin (Hepc) is a 25 amino acid cationic peptide with broad antibacterial and antifungal actions. A likely role for Hepc in iron metabolism was suggested by the observation that mice having disruption of the gene encoding the transcription factor USF2 failed to produce Hepc mRNA and developed spontaneous visceral i...

journal_title：Biological research

authors： Mena NP,Esparza AL,Núñez MT

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Asthma is a complex disease influenced by multiple genetic and environmental factors. While Madeira has the highest prevalence of asthma in Portugal (14.6%), the effect of both genetic and environmental factors in this population has never been assessed. We categorized 98 asthma patients according to the Glo...

journal_title：Biological research

authors： Berenguer AG,Fernandes AT,Oliveira S,Rodrigues M,Ornelas P,Romeira D,Serrão T,Rosa A,Câmara R

更新日期：2014-09-04 00:00:00

abstract：:Transducin serves as a mediator between the receptor protein, rhodopsin, and the effector protein, cGMP phosphodiesterase, in the visual process. Transducin is a protein composed of three polypeptides: T alpha, T beta, and T gamma, and acts as two functional units, the alpha-subunit and the beta gamma-complex. In the ...

journal_title：Biological research

authors： Bubis J

更新日期：1995-01-01 00:00:00

abstract：:The anti-inflammatory and redox protective effects of the citronellal (CT) were evaluated using in vivo and in vitro tests. Intraperitoneal (i.p.) administration of CT (50, 100, and 200 mg/kg) inhibited (p < 0.05) the carrageenan-induced leukocyte migration to the peritoneal cavity. Additionally, the carrageenan- and ...

journal_title：Biological research

authors： Melo MS,Guimarães AG,Santana MF,Siqueira RS,De Lima Ado C,Dias AS,Santos MR,Onofre AS,Quintans JS,De Sousa DP,Almeida JR,Estevam CS,Araujo BS,Quintans-Júnior LJ

更新日期：2011-01-01 00:00:00

abstract：:Vasopressin and bradykinin are two of the most important peptides in regulating vascular tone, water, and ionic balance in the body, and thus they play a key role in controlling blood pressure. In addition to being a potent vasoconstrictor, Vasopressin also has an antidiuretic activity in the kidney, whereas kinins re...

journal_title：Biological research

authors： Gonzalez CB,Figueroa CD

更新日期：1999-01-01 00:00:00

abstract：:The aim of this study was to compare the effects of Mediterranean-type diet (MD), high-fat diet (HFD), and red wine supplementation on plasma concentration of emergent haemostatic cardiovascular risk factors (HCVRF) and on variables of primary haemostasis (bleeding time, plasma von Willebrand factor and platelet aggre...

journal_title：Biological research

authors： Mezzano D

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Psoralen is a coumarin-like and coumarin-related benzofuran glycoside, which is a commonly used traditional Chinese medicine to treat patients with kidney and spleen-yang deficiency symptom. Psoralen has been reported to show estrogen-like activity, antioxidant activity, osteoblastic proliferation accelerati...

journal_title：Biological research

authors： Wang X,Peng P,Pan Z,Fang Z,Lu W,Liu X

更新日期：2019-07-05 00:00:00

abstract：:Thymulin is a well-characterized thymic hormone that exists as a nonapeptide coupled to equimolar amounts of Zn2+. Thymulin is known to have multiple biological roles, including T cell differentiation, immune regulation, and analgesic functions. It has been shown that thymulin is produced by the reticulo-epithelial ce...

journal_title：Biological research

authors： Folch H,Villegas JV,Leyan V,Barría M,Eller G,Esquivel P

更新日期：2010-01-01 00:00:00

abstract：:Hearing loss is the most common inherited sensorial deficiency in humans; about 1 in 1000 children suffer from severe or profound hearing loss at birth. Mutations in the GJB2 gene are the most common cause of prelingual, non-syndromic autosomal recessive deafness in many populations; the c.35delG mutation is the most ...

journal_title：Biological research

authors： Cifuentes L,Arancibia M,Torrente M,Acuña M,Farfán C,Ríos C

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Conjunctival filtering bleb scar formation is the main reason for the failure of glaucoma filtration surgery. Cytoglobin (Cygb) has been reported to play an important role in extracellular matrix (ECM) remodeling, fibrosis and tissue damage repairing. This study aimed to investigate the role of Cygb in anti-...

journal_title：Biological research

authors： Wei H,Lin L,Zhang X,Feng Z,Wang Y,You Y,Wang X,Hou Y

更新日期：2019-04-16 00:00:00

abstract：BACKGROUND:The study was conducted to evaluate the in vitro thrombolytic activity, and in vivo analgesic, anti-inflammatory and antipyretic potentials of different hydrocarbon soluble extracts of Litsea glutinosa leaves for the first time widely used in the folkloric treatments in Bangladesh. This work aimed to create ...

journal_title：Biological research

authors： Bhowmick R,Sarwar MS,Dewan SM,Das A,Das B,Uddin MM,Islam MS,Islam MS

更新日期：2014-10-29 00:00:00

abstract：BACKGROUND:Impaired wound healing is a complication of diabetes and a serious problem in clinical practice. We previously found that whey protein (WP) was able to regulate wound healing normally in streptozotocin (STZ)-diabetic models. This subsequent study was designed to assess the effect of WP on heat shock protein-...

journal_title：Biological research

authors： Ahmed RR,Mahmoud A,Ahmed OM,Metwalli A,Ebaid H

更新日期：2015-10-01 00:00:00