Knockdown of ZFR suppresses cell proliferation and invasion of human pancreatic cancer.

abstract：:The purpose of this study was to carry out a bibliometric analysis of the articles published in Chile during 1987-2006 that were categorized into the Plant Science discipline by ISI. The data was extracted from the Web of Science datábase, obtaining a total of 911 articles for analysis. Almost half of the articles wer...

journal_title：Biological research

authors： Krauskopf E

更新日期：2008-01-01 00:00:00

abstract：:A peptide from hindguts of the Triatoma infestans, the hematophagous Chagas' insect vector, activates adenylyl cyclase activity in Trypanosoma cruzi epimastigote membranes and stimulates the in vitro differentiation of epimastigotes (proliferative and non-infectious forms) to metacyclic trypomastigotes (non-proliferat...

journal_title：Biological research

authors： Fraidenraich D,Peña C,Isola EL,Lammel EM,Coso O,Añel AD,Baralle F,Torres HN,Flawia MM

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Limonoids are highly oxygenated compounds with a prototypical structure. Their occurrence in the plant kingdom is mainly confined to plant families of Meliaceae and Rutaceae. Owing to their wide range of pharmacological and therapeutic properties, this study was aimed at investigating the potential nitric ox...

journal_title：Biological research

authors： Dzoyem JP,Tsamo AT,Melong R,Mkounga P,Nkengfack AE,McGaw LJ,Eloff JN

更新日期：2015-10-13 00:00:00

abstract：:Although evidence is accumulating that prenatal testosterone (T) compromises reproductive function in the female, the effects of excess T in utero on the postnatal development of male reproductive function has not been studied. The aim of this study was to assess the influence of prenatal T excess on age-related chang...

journal_title：Biological research

authors： Recabarren SE,Lobos A,Figueroa Y,Padmanabhan V,Foster DL,Sir-Petermann T

更新日期：2007-01-01 00:00:00

abstract：:The aim of this study was to compare the effects of Mediterranean-type diet (MD), high-fat diet (HFD), and red wine supplementation on plasma concentration of emergent haemostatic cardiovascular risk factors (HCVRF) and on variables of primary haemostasis (bleeding time, plasma von Willebrand factor and platelet aggre...

journal_title：Biological research

authors： Mezzano D

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:chronic hypoxia increases basal ventilation and pulmonary vascular resistance, with variable changes in arterial blood pressure and heart rate, but it's impact on heart rate variability and autonomic regulation have been less well examined. We studied changes in arterial blood pressure, heart rate and heart ...

journal_title：Biological research

authors： Alcayaga J,Del Rio R,Moya EA,Freire M,Iturriaga R

更新日期：2018-12-20 00:00:00

abstract：:Despite the fact that the concept of sheet-flow in the pulmonary microcirculation of mammals was introduced more than three decades ago, the capillary circulatory model still prevails in the physiological literature. Since cardiac output is identical in the systemic and in pulmonary circulations, it is noteworthy that...

journal_title：Biological research

authors： Günther B,Morgado E,Cociña M

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:α-Farnesene is a volatile sesquiterpene synthesized by the plant mevalonate (MVA) pathway through the action of α-farnesene synthase. The α-farnesene synthase 1 (MdAFS1) gene was isolated from apple peel (var. white winter pearmain), and transformed into tobacco (Nicotiana tabacum NC89). The transgenic plant...

journal_title：Biological research

authors： Liu Y,Wang L,Liu H,Zhao R,Liu B,Fu Q,Zhang Y

更新日期：2016-07-02 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is highly aggressive with poor prognosis. Long non-coding RNAs (lncRNAs), a group of non-coding RNAs, play important roles in the progression of PDAC. This study aimed to investigate the potential involvement of lncRNA CCAT2 in PDAC tumorigenesis. METHODS:Expression o...

journal_title：Biological research

authors： Cai Y,Li X,Shen P,Zhang D

更新日期：2018-01-03 00:00:00

abstract：:Oxidant/antioxidant imbalance has been reported in some infectious diseases, including community-acquired pneumonia (CAP). The aim was to assess the antioxidant status in adults with CAP and its relationship with clinical severity at admission. Fifty-nine patients with CAP were enrolled and categorized at admission by...

journal_title：Biological research

authors： Castillo RL,Carrasco RA,Alvarez PI,Ruiz M,Luchsinger V,Zunino E,Martínez MA,Avendaño LF

更新日期：2013-01-01 00:00:00

abstract：:The development of an effective hypersensitive response (HR) in any plant system relies, not only in their gene composition and expression, but also on an effective and rapid signal transduction system. Lemon seedlings induce the phenylpropanoid pathway, which results in the de novo biosynthesis of the phytoalexin sco...

journal_title：Biological research

authors： Ortega X,Polanco R,Castañeda P,Perez LM

更新日期：2002-01-01 00:00:00

abstract：:Eight Chilean strains of Dunaliella salina obtained within a restricted geographic range, but exhibiting a high variability in their morphology, rate of growth and carotenogenic capacity, were analyzed by Random Amplified Polymorphic DNA (RAPD-PCR) Twenty of the 50 random primers (D, P, OPA and OPD series) that were t...

journal_title：Biological research

authors： Gomez PI,Gonzalez MA

更新日期：2001-01-01 00:00:00

abstract：:Caffeic acid, rosmarinic acid and oligomers of caffeic acid with multiple catechol groups are all constituents of Salvia officinalis. Their antioxidant potential was investigated with regard to their radical scavenging activity and the stability and structure of the intermediate radicals. Pulse-radiolytic studies reve...

journal_title：Biological research

authors： Bors W,Michel C,Stettmaier K,Lu Y,Foo LY

更新日期：2004-01-01 00:00:00

abstract：:The electrophysiological properties of neurons are determined by the expression of defined complements of ion channels. Nonetheless, the regulation mechanisms of the expression of neuronal ion channels are poorly understood, due in part to the diversity of neuron subtypes. We explored the expression of voltage-gated c...

journal_title：Biological research

authors： Olguín P,Armisen R,Kukuljan M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Accumulating studies have demonstrated that high-mobility group A2 (HMGA2), an oncofetal protein, plays a role in tumor development and progression. However, the molecular role of HMGA2 in ovarian carcinoma is yet to be established. MicroRNAs (miRNAs), a group of small noncoding RNAs, negatively regulate gen...

journal_title：Biological research

authors： Xing F,Song Z,He Y

更新日期：2018-11-24 00:00:00

abstract：BACKGROUND:Understanding the molecular basis underlying the formation of bone-forming osteocytes and lipid-storing adipocytes will help provide insights into the cause of disorders originating in stem/progenitor cells and develop therapeutic treatments for bone- or adipose-related diseases. In this study, the role of R...

journal_title：Biological research

authors： Madrigal A,Tan L,Zhao Y

更新日期：2017-12-26 00:00:00

abstract：:Bilateral aspiration lesions of the fimbria-fornix were performed in 10 male Sprague Dawley rats weighing 240-300 g under chloral hydrate narcose (420 mg/kg). Another 9 animals were operated in the same way, but no aspiration was carried out to constitute a control group. A week after surgery recording and stimulation...

journal_title：Biological research

authors： Bergado JA,Moreno H,Nuñez N

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Left ventricular diastolic dysfunction is one of the main characteristics of heart failure patients with a preserved left ventricular ejection fraction. As bilirubin is regarded as an important endogenous antioxidant molecule, serum total bilirubin levels were compared between heart failure patients with a p...

journal_title：Biological research

authors： Zheng H,Li Y,Xie N

更新日期：2014-03-26 00:00:00

abstract：BACKGROUND:Ubiquitin specific peptidase 39 (USP39), an essential factor in the assembly of the mature spliceosome complex, has an aberrant expression in several cancer. However, its function and the corresponding mechanism on human osteosarcoma has not been fully explored yet. METHODS:The mRNA and DNA copies of USP39 ...

journal_title：Biological research

authors： Gan Z,Han K,Lin S,Hu H,Shen Z,Min D

更新日期：2017-04-12 00:00:00

abstract：BACKGROUND:This study aimed to determine the seasonal changes of total antioxidant activity and phenolic compounds in samples taken from leaves (April, July, October) and stems (April, July, October, January) of some almond (Prunus amygdalus L.) varieties (Nonpareil, Ferragnes and Texas). RESULTS:It was indicated that...

journal_title：Biological research

authors： Sivaci A,Duman S

更新日期：2014-04-01 00:00:00

abstract：:The hypothesis that the vacation-study-expectancy scholar regime produces most of the monthly rhythm of the age at menarche (AaM) was tested. Studies on monthly menarche incidence (MI) refuted climatic factors as a main factor in this rhythm, and indicated that the main factor of this rhythm is the succession of expec...

journal_title：Biological research

authors： Valenzuela CY

更新日期：2013-01-01 00:00:00

abstract：:Exposure to arsenic via drinking water is considered as a worldwide problem. Studies have shown that arsenic exposure during pregnancy affects embryogenesis and offspring development in rats and mice. Zinc as a micronutrient regulates many physiological functions, including an antioxidative role under various toxic co...

journal_title：Biological research

authors： Ahmad M,Wadaa MA,Farooq M,Daghestani MH,Sami AS

更新日期：2013-01-01 00:00:00

abstract：:Allium cepa L. meristems were used as a plant model to study the p53-independent control of S and G2 phases by checkpoint pathways, in eukaryotic cells. Checkpoint blocks were induced at early and mid S by hydroxyurea. After their spontaneous override, cells became accumulated in G2-prophase, giving rise later on to a...

journal_title：Biological research

authors： Pelayo HR,Pincheira J,Giménez-Abián JF,Clarke DJ,de la Torre C

更新日期：2003-01-01 00:00:00

abstract：:Skeletal muscles have the potential to regenerate by activation of quiescent satellite cells, however, the molecular signature that governs satellite cells during muscle regeneration is not well defined. Myosin light chains (Myls) are sarcomere-related proteins as traditional regulator of muscle contraction. In this r...

journal_title：Biological research

authors： Zhang SZ,Xu Y,Xie HQ,Li XQ,Wei YQ,Yang ZM

更新日期：2009-01-01 00:00:00

abstract：:The anti-inflammatory and redox protective effects of the citronellal (CT) were evaluated using in vivo and in vitro tests. Intraperitoneal (i.p.) administration of CT (50, 100, and 200 mg/kg) inhibited (p < 0.05) the carrageenan-induced leukocyte migration to the peritoneal cavity. Additionally, the carrageenan- and ...

journal_title：Biological research

authors： Melo MS,Guimarães AG,Santana MF,Siqueira RS,De Lima Ado C,Dias AS,Santos MR,Onofre AS,Quintans JS,De Sousa DP,Almeida JR,Estevam CS,Araujo BS,Quintans-Júnior LJ

更新日期：2011-01-01 00:00:00

abstract：:Interstitial fluid flow stress is one of the most important mechanical stimulations of bone cells under physiological conditions. Osteocytes and osteoblasts act as primary mechanosensors within bones, and in vitro are able to respond to fluid shear stress, both morphologically and functionally. However, there is littl...

journal_title：Biological research

authors： Xu H,Zhang J,Wu J,Guan Y,Weng Y,Shang P

更新日期：2012-01-01 00:00:00

abstract：:The present work was intended to evaluate the preparation of antigens, as well as the production and characterization of anti cAMP and cGMP antibodies. Such antibodies were obtained from rabbits, and we used 2'O-succinyl cyclic nucleotide derivate, conjugated with human serum albumin, as antigen. The characterization ...

journal_title：Biological research

authors： Defagot C,Zubin P

更新日期：1994-01-01 00:00:00

abstract：:The protein nucleolin, functionally involved in the main steps of ribosome biogenesis, is codified by a single copy gene in mammals. Here we report that at least three different genes codify for this protein in carp fish (Cyprinus carpio). This is the first description of the genomic organization of nucleolin in a tel...

journal_title：Biological research

authors： Quezada C,Navarro C,San Martín R,Alvarez M,Molina A,Vera MI

更新日期：2006-01-01 00:00:00

abstract：:In this article, we focus on the fundamental role of vitamin C transporters for the normal delivery of vitamin C to germ cells in the adluminal compartment of seminiferous tubules. We argue that the redox status within spermatozoa or in semen is partly responsible for the etiology of infertility. In this context, anti...

journal_title：Biological research

authors： Angulo C,Maldonado R,Pulgar E,Mancilla H,Córdova A,Villarroel F,Castro MA,Concha II

更新日期：2011-01-01 00:00:00

abstract：:Prolactin (PRL) is a pituitary hormone that plays important roles in mammalian reproductive physiology, specially lactation. The regulation of PRL secretion shows important species differences. To study PRL regulation in a subhuman primate, the Cebus apella, we developed an heterologous radioimmunoassay using an antib...

journal_title：Biological research

authors： Vásquez K,Vergara M,Recabarren M,Brandeis A,Serón-Ferré M

更新日期：1997-01-01 00:00:00