Knockdown of ZFR suppresses cell proliferation and invasion of human pancreatic cancer.

abstract：BACKGROUND:chronic hypoxia increases basal ventilation and pulmonary vascular resistance, with variable changes in arterial blood pressure and heart rate, but it's impact on heart rate variability and autonomic regulation have been less well examined. We studied changes in arterial blood pressure, heart rate and heart ...

journal_title：Biological research

authors： Alcayaga J,Del Rio R,Moya EA,Freire M,Iturriaga R

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:Understanding the molecular basis underlying the formation of bone-forming osteocytes and lipid-storing adipocytes will help provide insights into the cause of disorders originating in stem/progenitor cells and develop therapeutic treatments for bone- or adipose-related diseases. In this study, the role of R...

journal_title：Biological research

authors： Madrigal A,Tan L,Zhao Y

更新日期：2017-12-26 00:00:00

abstract：:Despite the fact that the concept of sheet-flow in the pulmonary microcirculation of mammals was introduced more than three decades ago, the capillary circulatory model still prevails in the physiological literature. Since cardiac output is identical in the systemic and in pulmonary circulations, it is noteworthy that...

journal_title：Biological research

authors： Günther B,Morgado E,Cociña M

更新日期：2005-01-01 00:00:00

abstract：:The development of an effective hypersensitive response (HR) in any plant system relies, not only in their gene composition and expression, but also on an effective and rapid signal transduction system. Lemon seedlings induce the phenylpropanoid pathway, which results in the de novo biosynthesis of the phytoalexin sco...

journal_title：Biological research

authors： Ortega X,Polanco R,Castañeda P,Perez LM

更新日期：2002-01-01 00:00:00

abstract：:Red blood cell carbonic anhydrase (CA) activity has not been studied in high altitude natives. Because CA is an intraerythocytic enzyme and high altitude natives are polycythemic, it is important to know if the activity of CA per red cell volume is different from that of their sea level counterparts. Blood was collect...

journal_title：Biological research

authors： Gamboa J,Caceda R,Gamboa A,Monge-C C

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Accumulating studies have demonstrated that high-mobility group A2 (HMGA2), an oncofetal protein, plays a role in tumor development and progression. However, the molecular role of HMGA2 in ovarian carcinoma is yet to be established. MicroRNAs (miRNAs), a group of small noncoding RNAs, negatively regulate gen...

journal_title：Biological research

authors： Xing F,Song Z,He Y

更新日期：2018-11-24 00:00:00

abstract：BACKGROUND:Limonoids are highly oxygenated compounds with a prototypical structure. Their occurrence in the plant kingdom is mainly confined to plant families of Meliaceae and Rutaceae. Owing to their wide range of pharmacological and therapeutic properties, this study was aimed at investigating the potential nitric ox...

journal_title：Biological research

authors： Dzoyem JP,Tsamo AT,Melong R,Mkounga P,Nkengfack AE,McGaw LJ,Eloff JN

更新日期：2015-10-13 00:00:00

abstract：:Bilateral aspiration lesions of the fimbria-fornix were performed in 10 male Sprague Dawley rats weighing 240-300 g under chloral hydrate narcose (420 mg/kg). Another 9 animals were operated in the same way, but no aspiration was carried out to constitute a control group. A week after surgery recording and stimulation...

journal_title：Biological research

authors： Bergado JA,Moreno H,Nuñez N

更新日期：1996-01-01 00:00:00

abstract：:Guanine nucleotide binding proteins (GTP-binding proteins) function as transducers of signals in different cellular processes. We have identified several GTP-binding proteins in Trypanosoma cruzi by Western blot analyses. Six polypeptide bands, p20, p25, p28, p31, p37 and p38, were specifically detected in epimastigot...

journal_title：Biological research

authors： Bubis J,Millan EJ,Martinez R

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:α-Farnesene is a volatile sesquiterpene synthesized by the plant mevalonate (MVA) pathway through the action of α-farnesene synthase. The α-farnesene synthase 1 (MdAFS1) gene was isolated from apple peel (var. white winter pearmain), and transformed into tobacco (Nicotiana tabacum NC89). The transgenic plant...

journal_title：Biological research

authors： Liu Y,Wang L,Liu H,Zhao R,Liu B,Fu Q,Zhang Y

更新日期：2016-07-02 00:00:00

abstract：:Exposure to arsenic via drinking water is considered as a worldwide problem. Studies have shown that arsenic exposure during pregnancy affects embryogenesis and offspring development in rats and mice. Zinc as a micronutrient regulates many physiological functions, including an antioxidative role under various toxic co...

journal_title：Biological research

authors： Ahmad M,Wadaa MA,Farooq M,Daghestani MH,Sami AS

更新日期：2013-01-01 00:00:00

abstract：:In this article, we focus on the fundamental role of vitamin C transporters for the normal delivery of vitamin C to germ cells in the adluminal compartment of seminiferous tubules. We argue that the redox status within spermatozoa or in semen is partly responsible for the etiology of infertility. In this context, anti...

journal_title：Biological research

authors： Angulo C,Maldonado R,Pulgar E,Mancilla H,Córdova A,Villarroel F,Castro MA,Concha II

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The root of Angelica sinensis (AS), also known as "Dang-gui," was a popular herbal medicine widely used in the treatment of gynecological diseases in China, Korea, and Japan for a long time. This study aimed to determine the effects of ethyl acetate fraction from Angelica sinensis (EAAS) on the interleukin-1...

journal_title：Biological research

authors： Lee WS,Lim JH,Sung MS,Lee EG,Oh YJ,Yoo WH

更新日期：2014-09-05 00:00:00

abstract：:Tumor growth is the result of combined cell proliferation overwhelming cell death and neoangiogenesis. This report shows CAM angiogenesis promoted by TA3 tumor supernatant with or without low dosis of betamethasone (Minimal antiangiogenic concentration: beta-MAAC). Methylcellulose discs instilled with 10 microliters o...

journal_title：Biological research

authors： Lemus D,Dabancens A,Illanes J,Fuenzalida M,Guerrero A,López C

更新日期：2001-01-01 00:00:00

abstract：:Interstitial fluid flow stress is one of the most important mechanical stimulations of bone cells under physiological conditions. Osteocytes and osteoblasts act as primary mechanosensors within bones, and in vitro are able to respond to fluid shear stress, both morphologically and functionally. However, there is littl...

journal_title：Biological research

authors： Xu H,Zhang J,Wu J,Guan Y,Weng Y,Shang P

更新日期：2012-01-01 00:00:00

abstract：:By using the fluorescent Ca2+ indicator fura 2, submicromolar levels of intracellular Ca2+ have been detected in Trypanosoma cruzi different stages. The intracellular transport mechanisms involved in maintaining Ca2+ homeostasis in T. cruzi have been characterized by measuring Ca2+ transport in digitonin-permeabilized...

journal_title：Biological research

authors： Docampo R

更新日期：1993-01-01 00:00:00

abstract：:Twelve biological variables were submitted to dimensional analysis in accordance with the MLT-system of physics (M, mass; L, length; T, time). Each of these variables has a characteristic numerical value for the exponents alpha for mass, beta for length, and gamma for time. By means of Newton's reduction coefficient (...

journal_title：Biological research

authors： Günther B,Gonzalez U,Morgado E

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:CD4+CD25highFOXP3+ regulatory T (Treg) cells, which include thymus-derived and peripherally induced cells, play a central role in immune regulation, and are therefore crucial to prevent graft-versus-host disease (GVHD). The increasing use of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for ...

journal_title：Biological research

authors： Takahashi H,Ikeda K,Ogawa K,Saito S,Ngoma AM,Mashimo Y,Ueda K,Furukawa M,Shichishima-Nakamura A,Ohkawara H,Nollet KE,Ohto H,Takeishi Y

更新日期：2015-07-26 00:00:00

abstract：BACKGROUND:This study aimed to determine the seasonal changes of total antioxidant activity and phenolic compounds in samples taken from leaves (April, July, October) and stems (April, July, October, January) of some almond (Prunus amygdalus L.) varieties (Nonpareil, Ferragnes and Texas). RESULTS:It was indicated that...

journal_title：Biological research

authors： Sivaci A,Duman S

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Impaired wound healing is a complication of diabetes and a serious problem in clinical practice. We previously found that whey protein (WP) was able to regulate wound healing normally in streptozotocin (STZ)-diabetic models. This subsequent study was designed to assess the effect of WP on heat shock protein-...

journal_title：Biological research

authors： Ahmed RR,Mahmoud A,Ahmed OM,Metwalli A,Ebaid H

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The Hawthorn (Crateagus sp.) mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn species grown in E...

journal_title：Biological research

authors： Gundogdu M,Ozrenk K,Ercisli S,Kan T,Kodad O,Hegedus A

更新日期：2014-05-30 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is highly aggressive with poor prognosis. Long non-coding RNAs (lncRNAs), a group of non-coding RNAs, play important roles in the progression of PDAC. This study aimed to investigate the potential involvement of lncRNA CCAT2 in PDAC tumorigenesis. METHODS:Expression o...

journal_title：Biological research

authors： Cai Y,Li X,Shen P,Zhang D

更新日期：2018-01-03 00:00:00

abstract：BACKGROUND:Left ventricular diastolic dysfunction is one of the main characteristics of heart failure patients with a preserved left ventricular ejection fraction. As bilirubin is regarded as an important endogenous antioxidant molecule, serum total bilirubin levels were compared between heart failure patients with a p...

journal_title：Biological research

authors： Zheng H,Li Y,Xie N

更新日期：2014-03-26 00:00:00

abstract：:Shigella flexneri causes bacillary dysentery in humans. Essential to the establishment of the disease is the invasion of the colonic epithelial cells. Here we investigated the role of the lipopolysaccharide (LPS) O antigen in the ability of S. flexneri to adhere to and invade polarized Caco-2 cells. The S. flexneri 2a...

journal_title：Biological research

authors： Hoare A,Bravo D,Martinić M,Valvano MA,Contreras I,Álvarez SA

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Psoriasis is a common chronic inflammatory skin disease. Keratinocytes hyperproliferation and excessive inflammatory response contribute to psoriasis pathogenesis. The agents able to attenuate keratinocytes hyperproliferation and excessive inflammatory response are considered to be potentially useful for pso...

journal_title：Biological research

authors： Gao J,Chen F,Fang H,Mi J,Qi Q,Yang M

更新日期：2020-10-20 00:00:00

abstract：:Thymulin is a well-characterized thymic hormone that exists as a nonapeptide coupled to equimolar amounts of Zn2+. Thymulin is known to have multiple biological roles, including T cell differentiation, immune regulation, and analgesic functions. It has been shown that thymulin is produced by the reticulo-epithelial ce...

journal_title：Biological research

authors： Folch H,Villegas JV,Leyan V,Barría M,Eller G,Esquivel P

更新日期：2010-01-01 00:00:00

abstract：:After the progress made during the genomics era, bioinformatics was tasked with supporting the flow of information generated by nanobiotechnology efforts. This challenge requires adapting classical bioinformatic and computational chemistry tools to store, standardize, analyze, and visualize nanobiotechnological inform...

journal_title：Biological research

authors： González-Nilo F,Pérez-Acle T,Guínez-Molinos S,Geraldo DA,Sandoval C,Yévenes A,Santos LS,Laurie VF,Mendoza H,Cachau RE

更新日期：2011-01-01 00:00:00

abstract：:Hyptidendron canum (Pohl ex Benth.) Harley is a native tree of the Brazilian Savannah. The fish Oreochromis niloticus L. was used as an experimental model to determine the bioactivity of the crude ethanol extract as well as ethyl acetate, hexanic and chloroform fractions obtained from its leaves. The plant ethanol ext...

journal_title：Biological research

authors： Fiuza TS,Silva PC,Paula JR,Tresvenzol LM,Sabóia-Morais SM

更新日期：2009-01-01 00:00:00

abstract：:Control of smooth muscle is vital for health. The major route to contraction is a rise in intracellular [Ca2+], determined by the entry and efflux of Ca2+ and release and re-uptake into the sarcoplasmic reticulum (SR). We review these processes in myometrium, to better understand excitation-contraction coupling and de...

journal_title：Biological research

authors： Matthew A,Shmygol A,Wray S

更新日期：2004-01-01 00:00:00

abstract：:Adenovirus genotype 7h was previously reported to be originated from a recombination event between adenovirus genotypes 7p and 3p. Based on those findings, further characterization of other adenovirus 7h strains become important to determine whether all adenovirus 7h strains arose from a single recombinational event. ...

journal_title：Biological research

authors： Bruzzone M,Barro M,Spencer E

更新日期：2001-01-01 00:00:00