Cytotoxicity, nitric oxide and acetylcholinesterase inhibitory activity of three limonoids isolated from Trichilia welwitschii (Meliaceae).

abstract：BACKGROUND:α-Farnesene is a volatile sesquiterpene synthesized by the plant mevalonate (MVA) pathway through the action of α-farnesene synthase. The α-farnesene synthase 1 (MdAFS1) gene was isolated from apple peel (var. white winter pearmain), and transformed into tobacco (Nicotiana tabacum NC89). The transgenic plant...

journal_title：Biological research

authors： Liu Y,Wang L,Liu H,Zhao R,Liu B,Fu Q,Zhang Y

更新日期：2016-07-02 00:00:00

abstract：:The aim of this study was to compare the effects of Mediterranean-type diet (MD), high-fat diet (HFD), and red wine supplementation on plasma concentration of emergent haemostatic cardiovascular risk factors (HCVRF) and on variables of primary haemostasis (bleeding time, plasma von Willebrand factor and platelet aggre...

journal_title：Biological research

authors： Mezzano D

更新日期：2004-01-01 00:00:00

abstract：:The expression of the acetyl xylan esterase II (axeII) gene from Penicillium purpurogenum is repressed by glucose and induced by xylan, as well as to a small degree by xylose and xylitol. This gene is expressed at neutral pH, but not under alkaline or acidic conditions, in agreement with previous findings for other xy...

journal_title：Biological research

authors： Chávez R,Schachter K,Navarro C,Peirano A,Bull P,Eyzaguirre J

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The role of interleukin family in colon cancer remained controversial. The purpose of this study was to investigate the association between interleukin family and colon cancer progression through bioinformatics methods and to validate such association in clinical patients. METHODS:A total of 15 differential...

journal_title：Biological research

authors： Wei X,Zhang Y,Yang Z,Sha Y,Pan Y,Chen Y,Cai L

更新日期：2020-05-07 00:00:00

abstract：BACKGROUND:Plants of Agave spp. perform Crassulacean acid metabolism (CAM) and are highly drought-tolerant, but little is known concerning seed germination under low water availability. The aim of this study was to assess the effect of substrate water potential (ΨW) on seed germination and contrast hydrotime parameters...

journal_title：Biological research

authors： Ramírez-Tobías HM,Peña-Valdivia CB,Trejo C,Aguirre R JR,Vaquera H H

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is a common arthritic disease and multifactorial whole-joint disease. Interactions of chemokines and OA is inadequately documented. RESULTS:In vivo and in vitro studies were conducted to investigate monocyte chemoattractant protein 1 (MCP-1) and receptor chemokine (C-C motif) receptor 2 ...

journal_title：Biological research

authors： Xu YK,Ke Y,Wang B,Lin JH

更新日期：2015-11-17 00:00:00

abstract：:Loss of Imprinting (LOI) of IGF2 and over-expressed IGF2 are associated with tumorigenesis. Our previous epidemiological study found a relatively high frequency of IGF2 LOI in healthy mid-gestation pregnant women. The aim of this study is to determine whether the expression of IGF2 is associated with its imprinting st...

journal_title：Biological research

authors： Ru-Fei G,Xue-Qing L,Ying-Xiong W,Xue-Mei C,Yu-Bin D,Jun-Lin H

更新日期：2012-01-01 00:00:00

abstract：:Object recognition memory allows discrimination between novel and familiar objects. This kind of memory consists of two components: recollection, which depends on the hippocampus, and familiarity, which depends on the perirhinal cortex (Pcx). The importance of brain-derived neurotrophic factor (BDNF) for recognition m...

journal_title：Biological research

authors： Muñoz PC,Aspé MA,Contreras LS,Palacios AG

更新日期：2010-01-01 00:00:00

abstract：:Hepcidin (Hepc) is a 25 amino acid cationic peptide with broad antibacterial and antifungal actions. A likely role for Hepc in iron metabolism was suggested by the observation that mice having disruption of the gene encoding the transcription factor USF2 failed to produce Hepc mRNA and developed spontaneous visceral i...

journal_title：Biological research

authors： Mena NP,Esparza AL,Núñez MT

更新日期：2006-01-01 00:00:00

abstract：:The species Heteropterys aphrodisiaca is commonly used as a stimulant by popular medicine in the Cerrado, a savanna-like biome, Brazil. Recent studies have proved its protective effects on testes of animals submitted to treatment using Cyclosporine A, as well as its stimulus effect in increasing testosterone secretion...

journal_title：Biological research

authors： Gomes ML,Monteiro JC,Freitas KM,Sbervelheri MM,Dolder H

更新日期：2011-01-01 00:00:00

abstract：:Breast cancer is the most common malignancy among women. Chilean studies reveal that this cancer presents the third highest mortality rate. A family history of breast cancer is one of the major risk factors for the development of this disease. BRCA1 and BRCA2 are the two main hereditary breast cancer susceptibility ge...

journal_title：Biological research

authors： Jara L,Ampuero S,Seccia L,Bustamante M,Blanco R,Ojeda JM

更新日期：2002-01-01 00:00:00

abstract：:Vasopressin and bradykinin are two of the most important peptides in regulating vascular tone, water, and ionic balance in the body, and thus they play a key role in controlling blood pressure. In addition to being a potent vasoconstrictor, Vasopressin also has an antidiuretic activity in the kidney, whereas kinins re...

journal_title：Biological research

authors： Gonzalez CB,Figueroa CD

更新日期：1999-01-01 00:00:00

abstract：:Shigella flexneri causes bacillary dysentery in humans. Essential to the establishment of the disease is the invasion of the colonic epithelial cells. Here we investigated the role of the lipopolysaccharide (LPS) O antigen in the ability of S. flexneri to adhere to and invade polarized Caco-2 cells. The S. flexneri 2a...

journal_title：Biological research

authors： Hoare A,Bravo D,Martinić M,Valvano MA,Contreras I,Álvarez SA

更新日期：2012-01-01 00:00:00

abstract：:We review the development of our knowledge and interpretations of the intermediary metabolism of Trypanosoma (Schizotrypanum) cruzi. Already in the 1950's it was clearly established that when this organism was exposed to large external concentrations of carbohydrates it was unable to catabolize them completely, even i...

journal_title：Biological research

authors： Urbina JA,Machin I,Jurado L

更新日期：1993-01-01 00:00:00

abstract：:Control of smooth muscle is vital for health. The major route to contraction is a rise in intracellular [Ca2+], determined by the entry and efflux of Ca2+ and release and re-uptake into the sarcoplasmic reticulum (SR). We review these processes in myometrium, to better understand excitation-contraction coupling and de...

journal_title：Biological research

authors： Matthew A,Shmygol A,Wray S

更新日期：2004-01-01 00:00:00

abstract：:The objective of this study was to test the hypothesis that root of maguey (Agave salmiana Otto ex Salm-Dyck) seedlings reacts during the first 24 h to low substrate water potential (PsiW), by anatomical modifications. Three-4 cm root length seedlings were planted in vermiculite for 24 h at PsiW between -0.03 and -2.3...

journal_title：Biological research

authors： Peña-Valdivia CB,Sánchez-Urdaneta AB

更新日期：2009-01-01 00:00:00

abstract：:Adenovirus genotype 7h was previously reported to be originated from a recombination event between adenovirus genotypes 7p and 3p. Based on those findings, further characterization of other adenovirus 7h strains become important to determine whether all adenovirus 7h strains arose from a single recombinational event. ...

journal_title：Biological research

authors： Bruzzone M,Barro M,Spencer E

更新日期：2001-01-01 00:00:00

abstract：:The radiobiocomplexes labeled with technetium-99m (Tc-99m) have been widely used in nuclear medicine in single photon emission computed tomography and in basic research. The aim of this study was to assess the influence of a Nectandra membranacea extract on the bioavailability of the sodium pertechnetate (Na(99m)TcO(4...

journal_title：Biological research

authors： Moreno SR,Arnobio A,De Carvalho JJ,Nascimento L,Oliveira Timoteo M,Olej B,Rocha EK,Pereira M,Bernardo-Filho M,Caldas LQ

更新日期：2007-01-01 00:00:00

abstract：:Hearing loss is the most common inherited sensorial deficiency in humans; about 1 in 1000 children suffer from severe or profound hearing loss at birth. Mutations in the GJB2 gene are the most common cause of prelingual, non-syndromic autosomal recessive deafness in many populations; the c.35delG mutation is the most ...

journal_title：Biological research

authors： Cifuentes L,Arancibia M,Torrente M,Acuña M,Farfán C,Ríos C

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Psoriasis is a common chronic inflammatory skin disease. Keratinocytes hyperproliferation and excessive inflammatory response contribute to psoriasis pathogenesis. The agents able to attenuate keratinocytes hyperproliferation and excessive inflammatory response are considered to be potentially useful for pso...

journal_title：Biological research

authors： Gao J,Chen F,Fang H,Mi J,Qi Q,Yang M

更新日期：2020-10-20 00:00:00

abstract：:After the progress made during the genomics era, bioinformatics was tasked with supporting the flow of information generated by nanobiotechnology efforts. This challenge requires adapting classical bioinformatic and computational chemistry tools to store, standardize, analyze, and visualize nanobiotechnological inform...

journal_title：Biological research

authors： González-Nilo F,Pérez-Acle T,Guínez-Molinos S,Geraldo DA,Sandoval C,Yévenes A,Santos LS,Laurie VF,Mendoza H,Cachau RE

更新日期：2011-01-01 00:00:00

abstract：:Compared with morphological and life history traits, quantitative genetic variation of metabolic and related traits in animals has been poorly studied. We used flow-through VCO(2) respirometry and simultaneous activity measurement on nymphs of the sand cricket (Gryllus firmus) from inbred lines to estimate broad-sense...

journal_title：Biological research

authors： Nespolo RF,Castañeda LE,Roff DA

更新日期：2007-01-01 00:00:00

abstract：:The protein nucleolin, functionally involved in the main steps of ribosome biogenesis, is codified by a single copy gene in mammals. Here we report that at least three different genes codify for this protein in carp fish (Cyprinus carpio). This is the first description of the genomic organization of nucleolin in a tel...

journal_title：Biological research

authors： Quezada C,Navarro C,San Martín R,Alvarez M,Molina A,Vera MI

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:miR-214 was demonstrated to be upregulated in models of renal disease and promoted fibrosis in renal injury independent of TGF-β signaling in vivo. However, the detailed role of miR-214 in acute kidney injury (AKI) and its underlying mechanism are still largely unknown. METHODS:In this study, an I/R-induced...

journal_title：Biological research

authors： Zhu X,Li W,Li H

更新日期：2018-09-04 00:00:00

abstract：:7-ketocholesterol (7-KC) differs from cholesterol by a functional ketone group at C7. It is an oxygenated cholesterol derivative (oxysterol), commonly present in oxidized low-density lipoprotein (LDL). Oxysterols are generated and participate in several physiologic and pathophysiologic processes. For instance, the cyt...

journal_title：Biological research

authors： Favero GM,Maranhão RC,Maria DA,Levy D,Bydlowski SP

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:chronic hypoxia increases basal ventilation and pulmonary vascular resistance, with variable changes in arterial blood pressure and heart rate, but it's impact on heart rate variability and autonomic regulation have been less well examined. We studied changes in arterial blood pressure, heart rate and heart ...

journal_title：Biological research

authors： Alcayaga J,Del Rio R,Moya EA,Freire M,Iturriaga R

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:Conjunctival filtering bleb scar formation is the main reason for the failure of glaucoma filtration surgery. Cytoglobin (Cygb) has been reported to play an important role in extracellular matrix (ECM) remodeling, fibrosis and tissue damage repairing. This study aimed to investigate the role of Cygb in anti-...

journal_title：Biological research

authors： Wei H,Lin L,Zhang X,Feng Z,Wang Y,You Y,Wang X,Hou Y

更新日期：2019-04-16 00:00:00

abstract：:Hematopoietic stem cell transplantation is the accepted therapy of choice for a variety of malignant and non-malignant diseases in children and adults. Initially developed as rescue therapy for a patient with cancer after high doses of chemotherapy and radiation as well as the correction of severe deficiencies in the ...

journal_title：Biological research

authors： Barriga F,Ramírez P,Wietstruck A,Rojas N

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study is to describe the ultrastructural changes of the egg apparatus associated with fertilisation of the natural tetraploid Trifolium pratense. The pollen tube enters one of the synergids through the filliform apparatus from the micropyle. Before the entry of the pollen tube into the embryo sac, one ...

journal_title：Biological research

authors： Buyukkartal HN

更新日期：2009-01-01 00:00:00

abstract：:The electrophysiological properties of neurons are determined by the expression of defined complements of ion channels. Nonetheless, the regulation mechanisms of the expression of neuronal ion channels are poorly understood, due in part to the diversity of neuron subtypes. We explored the expression of voltage-gated c...

journal_title：Biological research

authors： Olguín P,Armisen R,Kukuljan M

更新日期：2006-01-01 00:00:00