The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritis.

abstract：:Changes in the redox state of the intracellular ryanodine receptor/Ca2+ release channels of skeletal and cardiac muscle or brain cortex neurons affect their activity. In particular, agents that oxidize or alkylate free SH residues of the channel protein strongly enhance Ca(2+)-induced Ca2+ release, whereas reducing ag...

journal_title：Biological research

authors： Hidalgo C,Bull R,Behrens MI,Donoso P

更新日期：2004-01-01 00:00:00

abstract：:Exposure to arsenic via drinking water is considered as a worldwide problem. Studies have shown that arsenic exposure during pregnancy affects embryogenesis and offspring development in rats and mice. Zinc as a micronutrient regulates many physiological functions, including an antioxidative role under various toxic co...

journal_title：Biological research

authors： Ahmad M,Wadaa MA,Farooq M,Daghestani MH,Sami AS

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to compare the effects of Mediterranean-type diet (MD), high-fat diet (HFD), and red wine supplementation on plasma concentration of emergent haemostatic cardiovascular risk factors (HCVRF) and on variables of primary haemostasis (bleeding time, plasma von Willebrand factor and platelet aggre...

journal_title：Biological research

authors： Mezzano D

更新日期：2004-01-01 00:00:00

abstract：:The objective of this study was to test the hypothesis that root of maguey (Agave salmiana Otto ex Salm-Dyck) seedlings reacts during the first 24 h to low substrate water potential (PsiW), by anatomical modifications. Three-4 cm root length seedlings were planted in vermiculite for 24 h at PsiW between -0.03 and -2.3...

journal_title：Biological research

authors： Peña-Valdivia CB,Sánchez-Urdaneta AB

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The Tridax procumbens flavonoids (TPF), are well known for their medicinal properties among local natives. The TPF are traditionally used for dropsy, anaemia, arthritis, gout, asthma, ulcer, piles, and urinary problems. It also used in treating gastric problems, body pain, and rheumatic pains of joints. The ...

journal_title：Biological research

authors： Al Mamun MA,Islam K,Alam MJ,Khatun A,Alam MM,Al-Bari MA,Alam MJ

更新日期：2015-09-12 00:00:00

abstract：:Control of smooth muscle is vital for health. The major route to contraction is a rise in intracellular [Ca2+], determined by the entry and efflux of Ca2+ and release and re-uptake into the sarcoplasmic reticulum (SR). We review these processes in myometrium, to better understand excitation-contraction coupling and de...

journal_title：Biological research

authors： Matthew A,Shmygol A,Wray S

更新日期：2004-01-01 00:00:00

abstract：:Bilateral aspiration lesions of the fimbria-fornix were performed in 10 male Sprague Dawley rats weighing 240-300 g under chloral hydrate narcose (420 mg/kg). Another 9 animals were operated in the same way, but no aspiration was carried out to constitute a control group. A week after surgery recording and stimulation...

journal_title：Biological research

authors： Bergado JA,Moreno H,Nuñez N

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Recently, a continuous growth of interest has been observed in antimicrobial peptides (AMPs) in the light of an alarming increase in resistance of bacteria and fungi against antibiotics. AMPs are used as biomarkers in diagnosis and monitoring of oral cavity pathologies. Therefore, the determination of specif...

journal_title：Biological research

authors： Jurczak A,Kościelniak D,Papież M,Vyhouskaya P,Krzyściak W

更新日期：2015-10-31 00:00:00

abstract：:The species Heteropterys aphrodisiaca is commonly used as a stimulant by popular medicine in the Cerrado, a savanna-like biome, Brazil. Recent studies have proved its protective effects on testes of animals submitted to treatment using Cyclosporine A, as well as its stimulus effect in increasing testosterone secretion...

journal_title：Biological research

authors： Gomes ML,Monteiro JC,Freitas KM,Sbervelheri MM,Dolder H

更新日期：2011-01-01 00:00:00

abstract：:The anti-inflammatory and redox protective effects of the citronellal (CT) were evaluated using in vivo and in vitro tests. Intraperitoneal (i.p.) administration of CT (50, 100, and 200 mg/kg) inhibited (p < 0.05) the carrageenan-induced leukocyte migration to the peritoneal cavity. Additionally, the carrageenan- and ...

journal_title：Biological research

authors： Melo MS,Guimarães AG,Santana MF,Siqueira RS,De Lima Ado C,Dias AS,Santos MR,Onofre AS,Quintans JS,De Sousa DP,Almeida JR,Estevam CS,Araujo BS,Quintans-Júnior LJ

更新日期：2011-01-01 00:00:00

abstract：:Peroxisomes are thought to be formed by division of pre-existing peroxisomes after the import of newly synthesized proteins. However, it has been recently suggested that the endoplasmic reticulum (ER) provides an alternative de novo mechanism for peroxisome biogenesis in some cells. To test a possible role of the ER-G...

journal_title：Biological research

authors： Toro A,Arredondo C,Córdova G,Araya C,Palacios JL,Venegas A,Morita M,Imanaka T,Santos MJ

更新日期：2007-01-01 00:00:00

abstract：:This study examined the effects of estrogen supplementation on markers of neutrophil infiltration and damage in skeletal muscle of rats following ischemia. Male and female gonad-intact rats, with or without 14 days of estrogen supplementation were subjected to two hours of hind-limb ischemia and sacrificed at 24, 48 o...

journal_title：Biological research

authors： Tiidus PM,Deller M,Bombardier E,Gül M,Liu XL

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Prognosis remains one of most crucial determinants of gastric cancer (GC) treatment, but current methods do not predict prognosis accurately. Identification of additional biomarkers is urgently required to identify patients at risk of poor prognoses. METHODS:Tissue microarrays were used to measure expressio...

journal_title：Biological research

authors： Li W,Chen Y,Sun X,Yang J,Zhang DY,Wang D,Suo J

更新日期：2019-08-09 00:00:00

abstract：:Cells tightly regulate iron levels through the activity of iron regulatory proteins (IRPs) that bind to RNA motifs called iron responsive elements (IREs). When cells become iron-depleted, IRPs bind to IREs present in the mRNAs of ferritin and the transferrin receptor, resulting in diminished translation of the ferriti...

journal_title：Biological research

authors： Nuñez MT,Garate MA,Arredondo M,Tapia V,Muñoz P

更新日期：2000-01-01 00:00:00

abstract：:Unilateral brain damage which includes the hippocampus leads to memory impairments consistent with hemispheric specialization on the same side. Damage to the corpus callosum, the major connecting pathway between the left and right hemispheres, also leads to memory impairments. This suggests both hemispheric specializa...

journal_title：Biological research

authors： Zaidel DW

更新日期：1995-01-01 00:00:00

abstract：:7-ketocholesterol (7-KC) differs from cholesterol by a functional ketone group at C7. It is an oxygenated cholesterol derivative (oxysterol), commonly present in oxidized low-density lipoprotein (LDL). Oxysterols are generated and participate in several physiologic and pathophysiologic processes. For instance, the cyt...

journal_title：Biological research

authors： Favero GM,Maranhão RC,Maria DA,Levy D,Bydlowski SP

更新日期：2010-01-01 00:00:00

abstract：:Calcium regulation of several transcription factors involves different calcium-dependent signaling cascades and engages cytoplasmic as well as nuclear calcium signals. The study of the specific sources of calcium signals involved in regulation of gene expression in skeletal muscle has been addressed only recently. In ...

journal_title：Biological research

authors： Carrasco MA,Jaimovich E,Kemmerling U,Hidalgo C

更新日期：2004-01-01 00:00:00

abstract：:Object recognition memory allows discrimination between novel and familiar objects. This kind of memory consists of two components: recollection, which depends on the hippocampus, and familiarity, which depends on the perirhinal cortex (Pcx). The importance of brain-derived neurotrophic factor (BDNF) for recognition m...

journal_title：Biological research

authors： Muñoz PC,Aspé MA,Contreras LS,Palacios AG

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:chronic hypoxia increases basal ventilation and pulmonary vascular resistance, with variable changes in arterial blood pressure and heart rate, but it's impact on heart rate variability and autonomic regulation have been less well examined. We studied changes in arterial blood pressure, heart rate and heart ...

journal_title：Biological research

authors： Alcayaga J,Del Rio R,Moya EA,Freire M,Iturriaga R

更新日期：2018-12-20 00:00:00

abstract：:Loss of Imprinting (LOI) of IGF2 and over-expressed IGF2 are associated with tumorigenesis. Our previous epidemiological study found a relatively high frequency of IGF2 LOI in healthy mid-gestation pregnant women. The aim of this study is to determine whether the expression of IGF2 is associated with its imprinting st...

journal_title：Biological research

authors： Ru-Fei G,Xue-Qing L,Ying-Xiong W,Xue-Mei C,Yu-Bin D,Jun-Lin H

更新日期：2012-01-01 00:00:00

abstract：:The major cysteine proteinase from Trypanosoma cruzi, cruzipain, can be obtained essentially homogeneous, starting from crude epimastigote extracts, in one step, by affinity chromatography on Cystatin-Sepharose (specific for cysteine proteinases) or ConA-Sepharose (specific for high mannose N-linked glycoproteins). Th...

journal_title：Biological research

authors： Labriola C,Sousa M,Cazzulo JJ

更新日期：1993-01-01 00:00:00

abstract：:Guanine nucleotide binding proteins (GTP-binding proteins) function as transducers of signals in different cellular processes. We have identified several GTP-binding proteins in Trypanosoma cruzi by Western blot analyses. Six polypeptide bands, p20, p25, p28, p31, p37 and p38, were specifically detected in epimastigot...

journal_title：Biological research

authors： Bubis J,Millan EJ,Martinez R

更新日期：1993-01-01 00:00:00

abstract：:In the last few decades, several works on event related potentials (ERPs hereafter) during sleep have been reported. In spite of numerous studies, clear methodological rules for this kind of study are often missing, making it difficult to valorize the scope of these results. We propose here a description of methodolog...

journal_title：Biological research

authors： Ibáñez AM,San Martín R,Hurtado E,López V

更新日期：2008-01-01 00:00:00

abstract：:Galectins (S-type or S-Lac lectins) are a well-defined family of beta-galactoside animal lectins characterized by a high sequence homology in the carbohydrate-binding domain. We have previously purified and characterized the S-type lectin from the ovary of the toad Bufo arenarum. In this study, we purified the S-type ...

journal_title：Biological research

authors： Elola MT,Fink NE

更新日期：1997-01-01 00:00:00

abstract：:Allium cepa L. meristems were used as a plant model to study the p53-independent control of S and G2 phases by checkpoint pathways, in eukaryotic cells. Checkpoint blocks were induced at early and mid S by hydroxyurea. After their spontaneous override, cells became accumulated in G2-prophase, giving rise later on to a...

journal_title：Biological research

authors： Pelayo HR,Pincheira J,Giménez-Abián JF,Clarke DJ,de la Torre C

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Psoralen is a coumarin-like and coumarin-related benzofuran glycoside, which is a commonly used traditional Chinese medicine to treat patients with kidney and spleen-yang deficiency symptom. Psoralen has been reported to show estrogen-like activity, antioxidant activity, osteoblastic proliferation accelerati...

journal_title：Biological research

authors： Wang X,Peng P,Pan Z,Fang Z,Lu W,Liu X

更新日期：2019-07-05 00:00:00

abstract：:Breast cancer is the most common malignancy among women. Chilean studies reveal that this cancer presents the third highest mortality rate. A family history of breast cancer is one of the major risk factors for the development of this disease. BRCA1 and BRCA2 are the two main hereditary breast cancer susceptibility ge...

journal_title：Biological research

authors： Jara L,Ampuero S,Seccia L,Bustamante M,Blanco R,Ojeda JM

更新日期：2002-01-01 00:00:00

abstract：:Renal response to atrial natriuretic peptide in chronic cholestasis was studied in anaesthetized rats and in their isolated perfused kidneys. Cholestasis was induced by bile duct section after ligature, while controls were sham operated. Three weeks after surgery, cholestatic rats showed moderate arterial hypotension,...

journal_title：Biological research

authors： Valdivieso A,Boric MP,Riquelme A,Roblero J

更新日期：1993-01-01 00:00:00

abstract：:Compared with morphological and life history traits, quantitative genetic variation of metabolic and related traits in animals has been poorly studied. We used flow-through VCO(2) respirometry and simultaneous activity measurement on nymphs of the sand cricket (Gryllus firmus) from inbred lines to estimate broad-sense...

journal_title：Biological research

authors： Nespolo RF,Castañeda LE,Roff DA

更新日期：2007-01-01 00:00:00

abstract：:The historical, lexical and conceptual issues embedded in stem cell biology are reviewed from technical, ethical, philosophical, judicial, clinical, economic and biopolitical perspectives. The mechanisms assigning the simultaneous capacity to self-renew and to differentiate to stem cells (immortal template DNA and asy...

journal_title：Biological research

authors： Monti M,Perotti C,Del Fante C,Cervio M,Redi CA,Fondazione IRCCS Policlinico San Matteo, Pavia (Italia).

更新日期：2012-01-01 00:00:00