Abstract：
:Unilateral brain damage which includes the hippocampus leads to memory impairments consistent with hemispheric specialization on the same side. Damage to the corpus callosum, the major connecting pathway between the left and right hemispheres, also leads to memory impairments. This suggests both hemispheric specialization on the hippocampal level and a critical role for the corpus callosum in memory functions. A complete hippocampal formation is present on either side of the brain but traditionally only one is studied. However, a comparison between the neuronal populations in the hippocampus on both sides revealed asymmetry in connectivity among hippocampal subfields. The profile of memory impairments of commissurotomy ('split-brain') patients is described. The results are discussed in terms of a relationship between hippocampus and corpus callosum in humans. As hemispheric specialization evolved, inter-hippocampal connections became less important and the corpus callosum became prominent in memory functions.
journal_name
Biol Resjournal_title
Biological researchauthors
Zaidel DWsubject
Has Abstractpub_date
1995-01-01 00:00:00pages
51-7issue
1eissn
0716-9760issn
0717-6287journal_volume
28pub_type
杂志文章,评审abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is highly aggressive with poor prognosis. Long non-coding RNAs (lncRNAs), a group of non-coding RNAs, play important roles in the progression of PDAC. This study aimed to investigate the potential involvement of lncRNA CCAT2 in PDAC tumorigenesis. METHODS:Expression o...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-017-0149-0
更新日期：2018-01-03 00:00:00
abstract：:Invasive properties of 15 strains of thermotolerant Campylobacter (12 C. jejuni and 3 C. coli) were studied using HeLa cells cultures. In four of them (3 C. jejuni and 1 C. coli), randomly selected, intestinal perfusion experiments were conducted in order to asses enterotoxigenicity. All strains were able to invade He...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Transducin serves as a mediator between the receptor protein, rhodopsin, and the effector protein, cGMP phosphodiesterase, in the visual process. Transducin is a protein composed of three polypeptides: T alpha, T beta, and T gamma, and acts as two functional units, the alpha-subunit and the beta gamma-complex. In the ...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:The objective of this study was to test the hypothesis that root of maguey (Agave salmiana Otto ex Salm-Dyck) seedlings reacts during the first 24 h to low substrate water potential (PsiW), by anatomical modifications. Three-4 cm root length seedlings were planted in vermiculite for 24 h at PsiW between -0.03 and -2.3...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602009000200013
更新日期：2009-01-01 00:00:00
abstract：:X-Ray diffraction is the only method currently available for the determination of the detailed three-dimensional structure of macromolecules. In this article, the principles behind the use of X-ray crystallography in the study of protein structure are presented. The results obtained in its application to several enzym...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:miR-214 was demonstrated to be upregulated in models of renal disease and promoted fibrosis in renal injury independent of TGF-β signaling in vivo. However, the detailed role of miR-214 in acute kidney injury (AKI) and its underlying mechanism are still largely unknown. METHODS:In this study, an I/R-induced...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-018-0179-2
更新日期：2018-09-04 00:00:00
abstract：:In mammals, neurogenesis continues during adulthood in restricted places of the nervous system, namely the subventricular zone, the dentate gyms and the olfactory epithelium. A dual role of the second messenger nitric oxide has been reported in such places, either promoting or inhibiting proliferation of neuronal prec...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：10.4067/s0716-97602006000500002
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:IcarisideII (ICAII) could promote the differentiation of adipose tissue-derived stem cells (ADSCs) to Schwann cells (SCs), leading to improvement of erectile function (EF) and providing a realistic therapeutic option for the treatment of erectile dysfunction (ED). However, the underlying molecular mechanisms...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-019-0262-3
更新日期：2019-10-03 00:00:00
abstract：BACKGROUND:Asthma is a complex disease influenced by multiple genetic and environmental factors. While Madeira has the highest prevalence of asthma in Portugal (14.6%), the effect of both genetic and environmental factors in this population has never been assessed. We categorized 98 asthma patients according to the Glo...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/0717-6287-47-40
更新日期：2014-09-04 00:00:00
abstract：:The major cysteine proteinase from Trypanosoma cruzi, cruzipain, can be obtained essentially homogeneous, starting from crude epimastigote extracts, in one step, by affinity chromatography on Cystatin-Sepharose (specific for cysteine proteinases) or ConA-Sepharose (specific for high mannose N-linked glycoproteins). Th...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:chronic hypoxia increases basal ventilation and pulmonary vascular resistance, with variable changes in arterial blood pressure and heart rate, but it's impact on heart rate variability and autonomic regulation have been less well examined. We studied changes in arterial blood pressure, heart rate and heart ...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-018-0207-2
更新日期：2018-12-20 00:00:00
abstract：:Duchenne muscular dystrophy (DMD) is secondary to loss-of-function mutations in the dystrophin gene. The causes underlying the progression of DMD, differential muscle involvement, and the discrepancies in phenotypes among species with the same genetic defect are not understood. The mdx mouse, an animal model with dyst...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：10.4067/s0716-97602005000400010
更新日期：2005-01-01 00:00:00
abstract：:The anti-inflammatory and redox protective effects of the citronellal (CT) were evaluated using in vivo and in vitro tests. Intraperitoneal (i.p.) administration of CT (50, 100, and 200 mg/kg) inhibited (p < 0.05) the carrageenan-induced leukocyte migration to the peritoneal cavity. Additionally, the carrageenan- and ...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602011000400008
更新日期：2011-01-01 00:00:00
abstract：:Although several histone variants have been studied in both animal and plant organisms, little is known about their distribution during processes that involve alterations in chromatin function, such as differentiation, dedifferentiation and hormone treatment. In this study we evaluated the ratio of each histone varian...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602009000400006
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Despite manifold benefits of nanoparticles (NPs), less information on the risks of NPs to human health and environment has been studied. Cobalt oxide nanoparticles (Co3O4-NPs) have been reported to cause toxicity in several organisms. In this study, we have investigated the role of Co3O4-NPs in inducing phyt...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-016-0080-9
更新日期：2016-03-18 00:00:00
abstract：BACKGROUND:Although tropical climate of Thailand is suitably endowed with biodiversity of insects, flies of medical importance is not well investigated. Using information from literature search, fly survey approach and specialist's experience, we review database of Sarcophaga (Liosarcophaga) dux Thomson (Diptera: Sarco...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：10.1186/0717-6287-47-14
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:α-Farnesene is a volatile sesquiterpene synthesized by the plant mevalonate (MVA) pathway through the action of α-farnesene synthase. The α-farnesene synthase 1 (MdAFS1) gene was isolated from apple peel (var. white winter pearmain), and transformed into tobacco (Nicotiana tabacum NC89). The transgenic plant...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-016-0088-1
更新日期：2016-07-02 00:00:00
abstract：BACKGROUND:Psoriasis is a common chronic inflammatory skin disease. Keratinocytes hyperproliferation and excessive inflammatory response contribute to psoriasis pathogenesis. The agents able to attenuate keratinocytes hyperproliferation and excessive inflammatory response are considered to be potentially useful for pso...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-020-00316-0
更新日期：2020-10-20 00:00:00
abstract：:Angiotensin-(1-7) [Ang-(1-7)] possesses novel biological functions that are distinct from angiotensin II (Ang II). In coronary arteries, the octapeptide Ang II and the heptapeptide Ang-(1-7) exert opposing actions. Ang II elicits vasoconstriction and Ang-(1-7) is a vasodilator. Ang-(1-7) elicits vasodilation by an end...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:Papillary thyroid cancer (PTC) is the most common malignancy of all thyroid cancers. LncRNA LINC00460 has been proved to play roles in the oncogenesis and progression of various tumors, including papillary thyroid cancer. However, the potential molecular mechanism of LINC00460 in PTC is poorly investigated. ...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/s40659-019-0269-9
更新日期：2019-12-23 00:00:00
abstract：:Guanine nucleotide binding proteins (GTP-binding proteins) function as transducers of signals in different cellular processes. We have identified several GTP-binding proteins in Trypanosoma cruzi by Western blot analyses. Six polypeptide bands, p20, p25, p28, p31, p37 and p38, were specifically detected in epimastigot...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Three innovative and complementary morphological approaches were employed to study the T cell/antigen presenting cell (APC) interaction: (i) high resolution three-dimensional confocal microscopy of the T cell-APC contact site; (ii) time lapse video recording in living T cells of [Ca2+]I and changes in distribution of ...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：10.4067/s0716-97602002000200004
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Left ventricular diastolic dysfunction is one of the main characteristics of heart failure patients with a preserved left ventricular ejection fraction. As bilirubin is regarded as an important endogenous antioxidant molecule, serum total bilirubin levels were compared between heart failure patients with a p...
journal_title：Biological research
pub_type： 杂志文章
doi：10.1186/0717-6287-47-7
更新日期：2014-03-26 00:00:00
abstract：:The species Heteropterys aphrodisiaca is commonly used as a stimulant by popular medicine in the Cerrado, a savanna-like biome, Brazil. Recent studies have proved its protective effects on testes of animals submitted to treatment using Cyclosporine A, as well as its stimulus effect in increasing testosterone secretion...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602011000300004
更新日期：2011-01-01 00:00:00
abstract：:Most Colombian populations stem from the admixture of Caucasians, Amerindians and Negroids. In the world, these two latter ethnical groups show a significantly higher prevalence of epilepsy than the former one. We tested the hypothesis that the high prevalence of idiopathic epilepsy with generalized tonic clonic seizu...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Prolactin (PRL) is a pituitary hormone that plays important roles in mammalian reproductive physiology, specially lactation. The regulation of PRL secretion shows important species differences. To study PRL regulation in a subhuman primate, the Cebus apella, we developed an heterologous radioimmunoassay using an antib...
journal_title：Biological research
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:The development of plant transformation in the mid-1980s and of many new tools for cell biology, molecular genetics, and biochemistry has resulted in enormous progress in plant biology in the past decade. With the completion of the genome sequence of Arabidopsis thaliana just around the corner, we can expect even fast...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：:We review the development of our knowledge and interpretations of the intermediary metabolism of Trypanosoma (Schizotrypanum) cruzi. Already in the 1950's it was clearly established that when this organism was exposed to large external concentrations of carbohydrates it was unable to catabolize them completely, even i...
journal_title：Biological research
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
abstract：:The historical, lexical and conceptual issues embedded in stem cell biology are reviewed from technical, ethical, philosophical, judicial, clinical, economic and biopolitical perspectives. The mechanisms assigning the simultaneous capacity to self-renew and to differentiate to stem cells (immortal template DNA and asy...
journal_title：Biological research
pub_type： 历史文章,杂志文章,评审
doi：10.4067/S0716-97602012000300002
更新日期：2012-01-01 00:00:00
abstract：:The ascorbate-glutathione (ASC-GSH) cycle has an important role in defensive processes against oxidative damage generated by drought stress. In this study, the changes that take place in apoplastic and symplastic ASC-GSH cycle enzymes of the leaf and petiole were investigated under drought stress causing leaf rolling ...
journal_title：Biological research
pub_type： 杂志文章
doi：/S0716-97602009000300006
更新日期：2009-01-01 00:00:00
