Further studies on vertebrate S-type lectins: cross-reactivity between toad and human lectins.

Abstract:

:Galectins (S-type or S-Lac lectins) are a well-defined family of beta-galactoside animal lectins characterized by a high sequence homology in the carbohydrate-binding domain. We have previously purified and characterized the S-type lectin from the ovary of the toad Bufo arenarum. In this study, we purified the S-type lectins from Bufo arenarum ovary and human spleen by an improved method which included ion exchange and affinity chromatography. Antibody cross-reactivities between both lectins and some other S-type lectins showed that they share epitopes. Glycosylation studies carried out with detection/differentiation kits suggested that both lectins are not glycosylated.

journal_name

Biol Res

journal_title

Biological research

authors

Elola MT,Fink NE

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

99-104

issue

3

eissn

0716-9760

issn

0717-6287

journal_volume

30

pub_type

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