Analysis of 5382insC (BRCA1) and 6174delT (BRCA2) mutations in 382 healthy Chilean women with a family history of breast cancer.

abstract：:The neuropeptide oxytocin (OXT) is a key factor in the initiation and regulation of sociosexual behavior. The present study analyzes the effects of cohabitation and social challenge on plasma OXT concentration rates in guinea pig pairs in relation to male sociosexual behavior. The cohabitation phase lasted 3 days. On ...

journal_title：Biological research

authors： Wallner B,Dittami J,Machatschke I

更新日期：2006-01-01 00:00:00

abstract：:The regeneration of natural tetraploid T. pratense, originated from Erzurum-Turkey, is reported in this study. This plant has low seed setting and hard seed problems due to polyploidy. Hypocotyl, cotyledon, apical meristems, epicotyl and young primary leaves were inoculated on MS and PC-L2 media containing different c...

journal_title：Biological research

authors： Cölgeçen H,Toker MC

更新日期：2008-01-01 00:00:00

abstract：:The radiobiocomplexes labeled with technetium-99m (Tc-99m) have been widely used in nuclear medicine in single photon emission computed tomography and in basic research. The aim of this study was to assess the influence of a Nectandra membranacea extract on the bioavailability of the sodium pertechnetate (Na(99m)TcO(4...

journal_title：Biological research

authors： Moreno SR,Arnobio A,De Carvalho JJ,Nascimento L,Oliveira Timoteo M,Olej B,Rocha EK,Pereira M,Bernardo-Filho M,Caldas LQ

更新日期：2007-01-01 00:00:00

abstract：:The anti-inflammatory and redox protective effects of the citronellal (CT) were evaluated using in vivo and in vitro tests. Intraperitoneal (i.p.) administration of CT (50, 100, and 200 mg/kg) inhibited (p < 0.05) the carrageenan-induced leukocyte migration to the peritoneal cavity. Additionally, the carrageenan- and ...

journal_title：Biological research

authors： Melo MS,Guimarães AG,Santana MF,Siqueira RS,De Lima Ado C,Dias AS,Santos MR,Onofre AS,Quintans JS,De Sousa DP,Almeida JR,Estevam CS,Araujo BS,Quintans-Júnior LJ

更新日期：2011-01-01 00:00:00

abstract：:Twelve biological variables were submitted to dimensional analysis in accordance with the MLT-system of physics (M, mass; L, length; T, time). Each of these variables has a characteristic numerical value for the exponents alpha for mass, beta for length, and gamma for time. By means of Newton's reduction coefficient (...

journal_title：Biological research

authors： Günther B,Gonzalez U,Morgado E

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is a common arthritic disease and multifactorial whole-joint disease. Interactions of chemokines and OA is inadequately documented. RESULTS:In vivo and in vitro studies were conducted to investigate monocyte chemoattractant protein 1 (MCP-1) and receptor chemokine (C-C motif) receptor 2 ...

journal_title：Biological research

authors： Xu YK,Ke Y,Wang B,Lin JH

更新日期：2015-11-17 00:00:00

abstract：:Most Colombian populations stem from the admixture of Caucasians, Amerindians and Negroids. In the world, these two latter ethnical groups show a significantly higher prevalence of epilepsy than the former one. We tested the hypothesis that the high prevalence of idiopathic epilepsy with generalized tonic clonic seizu...

journal_title：Biological research

authors： Jiménez I,Mora O,Lopez G,Jiménez ME,Zuluga L,Isaza R,Sanchez JL,Uribe CS,Valenzuela CY,Blanco R,Arcos-Burgos M

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The Hawthorn (Crateagus sp.) mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn species grown in E...

journal_title：Biological research

authors： Gundogdu M,Ozrenk K,Ercisli S,Kan T,Kodad O,Hegedus A

更新日期：2014-05-30 00:00:00

abstract：BACKGROUND:The role of interleukin family in colon cancer remained controversial. The purpose of this study was to investigate the association between interleukin family and colon cancer progression through bioinformatics methods and to validate such association in clinical patients. METHODS:A total of 15 differential...

journal_title：Biological research

authors： Wei X,Zhang Y,Yang Z,Sha Y,Pan Y,Chen Y,Cai L

更新日期：2020-05-07 00:00:00

abstract：:Control of smooth muscle is vital for health. The major route to contraction is a rise in intracellular [Ca2+], determined by the entry and efflux of Ca2+ and release and re-uptake into the sarcoplasmic reticulum (SR). We review these processes in myometrium, to better understand excitation-contraction coupling and de...

journal_title：Biological research

authors： Matthew A,Shmygol A,Wray S

更新日期：2004-01-01 00:00:00

abstract：:The electrophysiological properties of neurons are determined by the expression of defined complements of ion channels. Nonetheless, the regulation mechanisms of the expression of neuronal ion channels are poorly understood, due in part to the diversity of neuron subtypes. We explored the expression of voltage-gated c...

journal_title：Biological research

authors： Olguín P,Armisen R,Kukuljan M

更新日期：2006-01-01 00:00:00

abstract：:Changes in the redox state of the intracellular ryanodine receptor/Ca2+ release channels of skeletal and cardiac muscle or brain cortex neurons affect their activity. In particular, agents that oxidize or alkylate free SH residues of the channel protein strongly enhance Ca(2+)-induced Ca2+ release, whereas reducing ag...

journal_title：Biological research

authors： Hidalgo C,Bull R,Behrens MI,Donoso P

更新日期：2004-01-01 00:00:00

abstract：:Calcium regulation of several transcription factors involves different calcium-dependent signaling cascades and engages cytoplasmic as well as nuclear calcium signals. The study of the specific sources of calcium signals involved in regulation of gene expression in skeletal muscle has been addressed only recently. In ...

journal_title：Biological research

authors： Carrasco MA,Jaimovich E,Kemmerling U,Hidalgo C

更新日期：2004-01-01 00:00:00

abstract：:Transducin serves as a mediator between the receptor protein, rhodopsin, and the effector protein, cGMP phosphodiesterase, in the visual process. Transducin is a protein composed of three polypeptides: T alpha, T beta, and T gamma, and acts as two functional units, the alpha-subunit and the beta gamma-complex. In the ...

journal_title：Biological research

authors： Bubis J

更新日期：1995-01-01 00:00:00

abstract：:Three innovative and complementary morphological approaches were employed to study the T cell/antigen presenting cell (APC) interaction: (i) high resolution three-dimensional confocal microscopy of the T cell-APC contact site; (ii) time lapse video recording in living T cells of [Ca2+]I and changes in distribution of ...

journal_title：Biological research

authors： Faroudi M,Zaru R,Favier B,Valitutti S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Papillary thyroid cancer (PTC) is the most common malignancy of all thyroid cancers. LncRNA LINC00460 has been proved to play roles in the oncogenesis and progression of various tumors, including papillary thyroid cancer. However, the potential molecular mechanism of LINC00460 in PTC is poorly investigated. ...

journal_title：Biological research

authors： Li G,Kong Q

更新日期：2019-12-23 00:00:00

abstract：BACKGROUND:The study was conducted to evaluate the in vitro thrombolytic activity, and in vivo analgesic, anti-inflammatory and antipyretic potentials of different hydrocarbon soluble extracts of Litsea glutinosa leaves for the first time widely used in the folkloric treatments in Bangladesh. This work aimed to create ...

journal_title：Biological research

authors： Bhowmick R,Sarwar MS,Dewan SM,Das A,Das B,Uddin MM,Islam MS,Islam MS

更新日期：2014-10-29 00:00:00

abstract：:Red blood cell carbonic anhydrase (CA) activity has not been studied in high altitude natives. Because CA is an intraerythocytic enzyme and high altitude natives are polycythemic, it is important to know if the activity of CA per red cell volume is different from that of their sea level counterparts. Blood was collect...

journal_title：Biological research

authors： Gamboa J,Caceda R,Gamboa A,Monge-C C

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Psoralen is a coumarin-like and coumarin-related benzofuran glycoside, which is a commonly used traditional Chinese medicine to treat patients with kidney and spleen-yang deficiency symptom. Psoralen has been reported to show estrogen-like activity, antioxidant activity, osteoblastic proliferation accelerati...

journal_title：Biological research

authors： Wang X,Peng P,Pan Z,Fang Z,Lu W,Liu X

更新日期：2019-07-05 00:00:00

abstract：:Prolactin (PRL) is a pituitary hormone that plays important roles in mammalian reproductive physiology, specially lactation. The regulation of PRL secretion shows important species differences. To study PRL regulation in a subhuman primate, the Cebus apella, we developed an heterologous radioimmunoassay using an antib...

journal_title：Biological research

authors： Vásquez K,Vergara M,Recabarren M,Brandeis A,Serón-Ferré M

更新日期：1997-01-01 00:00:00

abstract：:Peroxisomes are thought to be formed by division of pre-existing peroxisomes after the import of newly synthesized proteins. However, it has been recently suggested that the endoplasmic reticulum (ER) provides an alternative de novo mechanism for peroxisome biogenesis in some cells. To test a possible role of the ER-G...

journal_title：Biological research

authors： Toro A,Arredondo C,Córdova G,Araya C,Palacios JL,Venegas A,Morita M,Imanaka T,Santos MJ

更新日期：2007-01-01 00:00:00

abstract：:Exposure to arsenic via drinking water is considered as a worldwide problem. Studies have shown that arsenic exposure during pregnancy affects embryogenesis and offspring development in rats and mice. Zinc as a micronutrient regulates many physiological functions, including an antioxidative role under various toxic co...

journal_title：Biological research

authors： Ahmad M,Wadaa MA,Farooq M,Daghestani MH,Sami AS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Limonoids are highly oxygenated compounds with a prototypical structure. Their occurrence in the plant kingdom is mainly confined to plant families of Meliaceae and Rutaceae. Owing to their wide range of pharmacological and therapeutic properties, this study was aimed at investigating the potential nitric ox...

journal_title：Biological research

authors： Dzoyem JP,Tsamo AT,Melong R,Mkounga P,Nkengfack AE,McGaw LJ,Eloff JN

更新日期：2015-10-13 00:00:00

abstract：BACKGROUND:CCL2 was up-regulated in neurons and involved in microglia activation and neurological decline in mice suffering from hepatic encephalopathy (HE). However, no data exist concerning the effect of neuron-derived CCL2 on microglia activation in vitro. METHODS:The rats were pretreated with CCL2 receptor inhibit...

journal_title：Biological research

authors： Zhang L,Tan J,Jiang X,Qian W,Yang T,Sun X,Chen Z,Zhu Q

更新日期：2017-09-04 00:00:00

abstract：:The anti-tumor effect of R-Phycoerythrin (R-PE) from Porphyra haitanensis was studied using cell line HeLa as an in vitro model and Sarcoma-180 (S180) tumor-bearing mice as an in vivo model. The results showed that the combination treatment of R-PE and photodynamic therapy PDT) significantly inhibited the growth of He...

journal_title：Biological research

authors： Pan Q,Chen M,Li J,Wu Y,Zhen C,Liang B

更新日期：2013-01-01 00:00:00

abstract：:Allium cepa L. meristems were used as a plant model to study the p53-independent control of S and G2 phases by checkpoint pathways, in eukaryotic cells. Checkpoint blocks were induced at early and mid S by hydroxyurea. After their spontaneous override, cells became accumulated in G2-prophase, giving rise later on to a...

journal_title：Biological research

authors： Pelayo HR,Pincheira J,Giménez-Abián JF,Clarke DJ,de la Torre C

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:miR-214 was demonstrated to be upregulated in models of renal disease and promoted fibrosis in renal injury independent of TGF-β signaling in vivo. However, the detailed role of miR-214 in acute kidney injury (AKI) and its underlying mechanism are still largely unknown. METHODS:In this study, an I/R-induced...

journal_title：Biological research

authors： Zhu X,Li W,Li H

更新日期：2018-09-04 00:00:00

abstract：:The hypothesis that the vacation-study-expectancy scholar regime produces most of the monthly rhythm of the age at menarche (AaM) was tested. Studies on monthly menarche incidence (MI) refuted climatic factors as a main factor in this rhythm, and indicated that the main factor of this rhythm is the succession of expec...

journal_title：Biological research

authors： Valenzuela CY

更新日期：2013-01-01 00:00:00

abstract：:Despite the fact that the concept of sheet-flow in the pulmonary microcirculation of mammals was introduced more than three decades ago, the capillary circulatory model still prevails in the physiological literature. Since cardiac output is identical in the systemic and in pulmonary circulations, it is noteworthy that...

journal_title：Biological research

authors： Günther B,Morgado E,Cociña M

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Asthma is a complex disease influenced by multiple genetic and environmental factors. While Madeira has the highest prevalence of asthma in Portugal (14.6%), the effect of both genetic and environmental factors in this population has never been assessed. We categorized 98 asthma patients according to the Glo...

journal_title：Biological research

authors： Berenguer AG,Fernandes AT,Oliveira S,Rodrigues M,Ornelas P,Romeira D,Serrão T,Rosa A,Câmara R

更新日期：2014-09-04 00:00:00