Nanoinformatics: an emerging area of information technology at the intersection of bioinformatics, computational chemistry and nanobiotechnology.

abstract：:The radiobiocomplexes labeled with technetium-99m (Tc-99m) have been widely used in nuclear medicine in single photon emission computed tomography and in basic research. The aim of this study was to assess the influence of a Nectandra membranacea extract on the bioavailability of the sodium pertechnetate (Na(99m)TcO(4...

journal_title：Biological research

authors： Moreno SR,Arnobio A,De Carvalho JJ,Nascimento L,Oliveira Timoteo M,Olej B,Rocha EK,Pereira M,Bernardo-Filho M,Caldas LQ

更新日期：2007-01-01 00:00:00

abstract：:7-ketocholesterol (7-KC) differs from cholesterol by a functional ketone group at C7. It is an oxygenated cholesterol derivative (oxysterol), commonly present in oxidized low-density lipoprotein (LDL). Oxysterols are generated and participate in several physiologic and pathophysiologic processes. For instance, the cyt...

journal_title：Biological research

authors： Favero GM,Maranhão RC,Maria DA,Levy D,Bydlowski SP

更新日期：2010-01-01 00:00:00

abstract：:Shigella flexneri causes bacillary dysentery in humans. Essential to the establishment of the disease is the invasion of the colonic epithelial cells. Here we investigated the role of the lipopolysaccharide (LPS) O antigen in the ability of S. flexneri to adhere to and invade polarized Caco-2 cells. The S. flexneri 2a...

journal_title：Biological research

authors： Hoare A,Bravo D,Martinić M,Valvano MA,Contreras I,Álvarez SA

更新日期：2012-01-01 00:00:00

abstract：:The development of plant transformation in the mid-1980s and of many new tools for cell biology, molecular genetics, and biochemistry has resulted in enormous progress in plant biology in the past decade. With the completion of the genome sequence of Arabidopsis thaliana just around the corner, we can expect even fast...

journal_title：Biological research

authors： Chrispeels MJ,Holuigue L,Latorre R,Luan S,Orellana A,Peña-Cortes H,Raikhel NV,Ronald PC,Trewavas A

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:miR-214 was demonstrated to be upregulated in models of renal disease and promoted fibrosis in renal injury independent of TGF-β signaling in vivo. However, the detailed role of miR-214 in acute kidney injury (AKI) and its underlying mechanism are still largely unknown. METHODS:In this study, an I/R-induced...

journal_title：Biological research

authors： Zhu X,Li W,Li H

更新日期：2018-09-04 00:00:00

abstract：:Red blood cell carbonic anhydrase (CA) activity has not been studied in high altitude natives. Because CA is an intraerythocytic enzyme and high altitude natives are polycythemic, it is important to know if the activity of CA per red cell volume is different from that of their sea level counterparts. Blood was collect...

journal_title：Biological research

authors： Gamboa J,Caceda R,Gamboa A,Monge-C C

更新日期：2000-01-01 00:00:00

abstract：:Transducin serves as a mediator between the receptor protein, rhodopsin, and the effector protein, cGMP phosphodiesterase, in the visual process. Transducin is a protein composed of three polypeptides: T alpha, T beta, and T gamma, and acts as two functional units, the alpha-subunit and the beta gamma-complex. In the ...

journal_title：Biological research

authors： Bubis J

更新日期：1995-01-01 00:00:00

abstract：:By using the fluorescent Ca2+ indicator fura 2, submicromolar levels of intracellular Ca2+ have been detected in Trypanosoma cruzi different stages. The intracellular transport mechanisms involved in maintaining Ca2+ homeostasis in T. cruzi have been characterized by measuring Ca2+ transport in digitonin-permeabilized...

journal_title：Biological research

authors： Docampo R

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Prognosis remains one of most crucial determinants of gastric cancer (GC) treatment, but current methods do not predict prognosis accurately. Identification of additional biomarkers is urgently required to identify patients at risk of poor prognoses. METHODS:Tissue microarrays were used to measure expressio...

journal_title：Biological research

authors： Li W,Chen Y,Sun X,Yang J,Zhang DY,Wang D,Suo J

更新日期：2019-08-09 00:00:00

abstract：:Allium cepa L. meristems were used as a plant model to study the p53-independent control of S and G2 phases by checkpoint pathways, in eukaryotic cells. Checkpoint blocks were induced at early and mid S by hydroxyurea. After their spontaneous override, cells became accumulated in G2-prophase, giving rise later on to a...

journal_title：Biological research

authors： Pelayo HR,Pincheira J,Giménez-Abián JF,Clarke DJ,de la Torre C

更新日期：2003-01-01 00:00:00

abstract：:Eight Chilean strains of Dunaliella salina obtained within a restricted geographic range, but exhibiting a high variability in their morphology, rate of growth and carotenogenic capacity, were analyzed by Random Amplified Polymorphic DNA (RAPD-PCR) Twenty of the 50 random primers (D, P, OPA and OPD series) that were t...

journal_title：Biological research

authors： Gomez PI,Gonzalez MA

更新日期：2001-01-01 00:00:00

abstract：:The purpose of this study was to carry out a bibliometric analysis of the articles published in Chile during 1987-2006 that were categorized into the Plant Science discipline by ISI. The data was extracted from the Web of Science datábase, obtaining a total of 911 articles for analysis. Almost half of the articles wer...

journal_title：Biological research

authors： Krauskopf E

更新日期：2008-01-01 00:00:00

abstract：:The anti-tumor effect of R-Phycoerythrin (R-PE) from Porphyra haitanensis was studied using cell line HeLa as an in vitro model and Sarcoma-180 (S180) tumor-bearing mice as an in vivo model. The results showed that the combination treatment of R-PE and photodynamic therapy PDT) significantly inhibited the growth of He...

journal_title：Biological research

authors： Pan Q,Chen M,Li J,Wu Y,Zhen C,Liang B

更新日期：2013-01-01 00:00:00

abstract：:Unilateral brain damage which includes the hippocampus leads to memory impairments consistent with hemispheric specialization on the same side. Damage to the corpus callosum, the major connecting pathway between the left and right hemispheres, also leads to memory impairments. This suggests both hemispheric specializa...

journal_title：Biological research

authors： Zaidel DW

更新日期：1995-01-01 00:00:00

abstract：:Bilateral aspiration lesions of the fimbria-fornix were performed in 10 male Sprague Dawley rats weighing 240-300 g under chloral hydrate narcose (420 mg/kg). Another 9 animals were operated in the same way, but no aspiration was carried out to constitute a control group. A week after surgery recording and stimulation...

journal_title：Biological research

authors： Bergado JA,Moreno H,Nuñez N

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Plants of Agave spp. perform Crassulacean acid metabolism (CAM) and are highly drought-tolerant, but little is known concerning seed germination under low water availability. The aim of this study was to assess the effect of substrate water potential (ΨW) on seed germination and contrast hydrotime parameters...

journal_title：Biological research

authors： Ramírez-Tobías HM,Peña-Valdivia CB,Trejo C,Aguirre R JR,Vaquera H H

更新日期：2014-04-01 00:00:00

abstract：:The aim of this study was to compare the effects of Mediterranean-type diet (MD), high-fat diet (HFD), and red wine supplementation on plasma concentration of emergent haemostatic cardiovascular risk factors (HCVRF) and on variables of primary haemostasis (bleeding time, plasma von Willebrand factor and platelet aggre...

journal_title：Biological research

authors： Mezzano D

更新日期：2004-01-01 00:00:00

abstract：:Most Colombian populations stem from the admixture of Caucasians, Amerindians and Negroids. In the world, these two latter ethnical groups show a significantly higher prevalence of epilepsy than the former one. We tested the hypothesis that the high prevalence of idiopathic epilepsy with generalized tonic clonic seizu...

journal_title：Biological research

authors： Jiménez I,Mora O,Lopez G,Jiménez ME,Zuluga L,Isaza R,Sanchez JL,Uribe CS,Valenzuela CY,Blanco R,Arcos-Burgos M

更新日期：1996-01-01 00:00:00

abstract：:Prolactin (PRL) is a pituitary hormone that plays important roles in mammalian reproductive physiology, specially lactation. The regulation of PRL secretion shows important species differences. To study PRL regulation in a subhuman primate, the Cebus apella, we developed an heterologous radioimmunoassay using an antib...

journal_title：Biological research

authors： Vásquez K,Vergara M,Recabarren M,Brandeis A,Serón-Ferré M

更新日期：1997-01-01 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is secondary to loss-of-function mutations in the dystrophin gene. The causes underlying the progression of DMD, differential muscle involvement, and the discrepancies in phenotypes among species with the same genetic defect are not understood. The mdx mouse, an animal model with dyst...

journal_title：Biological research

authors： Fadic R

更新日期：2005-01-01 00:00:00

abstract：:Exposure to arsenic via drinking water is considered as a worldwide problem. Studies have shown that arsenic exposure during pregnancy affects embryogenesis and offspring development in rats and mice. Zinc as a micronutrient regulates many physiological functions, including an antioxidative role under various toxic co...

journal_title：Biological research

authors： Ahmad M,Wadaa MA,Farooq M,Daghestani MH,Sami AS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The root of Angelica sinensis (AS), also known as "Dang-gui," was a popular herbal medicine widely used in the treatment of gynecological diseases in China, Korea, and Japan for a long time. This study aimed to determine the effects of ethyl acetate fraction from Angelica sinensis (EAAS) on the interleukin-1...

journal_title：Biological research

authors： Lee WS,Lim JH,Sung MS,Lee EG,Oh YJ,Yoo WH

更新日期：2014-09-05 00:00:00

abstract：:Thymulin is a well-characterized thymic hormone that exists as a nonapeptide coupled to equimolar amounts of Zn2+. Thymulin is known to have multiple biological roles, including T cell differentiation, immune regulation, and analgesic functions. It has been shown that thymulin is produced by the reticulo-epithelial ce...

journal_title：Biological research

authors： Folch H,Villegas JV,Leyan V,Barría M,Eller G,Esquivel P

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Psoriasis is a common chronic inflammatory skin disease. Keratinocytes hyperproliferation and excessive inflammatory response contribute to psoriasis pathogenesis. The agents able to attenuate keratinocytes hyperproliferation and excessive inflammatory response are considered to be potentially useful for pso...

journal_title：Biological research

authors： Gao J,Chen F,Fang H,Mi J,Qi Q,Yang M

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:Prunella vulgaris L. is a medical plant cultivated in sloping, sun-shaded areas in China. Recently, owing to air-environmental stress, especially drought stress strongly inhibits plant growth and development, the appropriate fertilizer supply can alleviate these effects. However, these is little information ...

journal_title：Biological research

authors： Chen Y,Liu L,Guo Q,Zhu Z,Zhang L

更新日期：2016-02-24 00:00:00

abstract：:Hearing loss is the most common inherited sensorial deficiency in humans; about 1 in 1000 children suffer from severe or profound hearing loss at birth. Mutations in the GJB2 gene are the most common cause of prelingual, non-syndromic autosomal recessive deafness in many populations; the c.35delG mutation is the most ...

journal_title：Biological research

authors： Cifuentes L,Arancibia M,Torrente M,Acuña M,Farfán C,Ríos C

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:CCL2 was up-regulated in neurons and involved in microglia activation and neurological decline in mice suffering from hepatic encephalopathy (HE). However, no data exist concerning the effect of neuron-derived CCL2 on microglia activation in vitro. METHODS:The rats were pretreated with CCL2 receptor inhibit...

journal_title：Biological research

authors： Zhang L,Tan J,Jiang X,Qian W,Yang T,Sun X,Chen Z,Zhu Q

更新日期：2017-09-04 00:00:00

abstract：:Calcium regulation of several transcription factors involves different calcium-dependent signaling cascades and engages cytoplasmic as well as nuclear calcium signals. The study of the specific sources of calcium signals involved in regulation of gene expression in skeletal muscle has been addressed only recently. In ...

journal_title：Biological research

authors： Carrasco MA,Jaimovich E,Kemmerling U,Hidalgo C

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Changed temperature not only threaten agricultural production, but they also affect individual biological behavior, population and community of many insects, and consequently reduce the stability of our ecosystem. Insect's ability to respond to temperature stress evolved through a complex adaptive process, t...

journal_title：Biological research

authors： Zhang Y,Wu H,Xie J,Jiang R,Deng C,Pang H

更新日期：2015-11-19 00:00:00

abstract：:Control of smooth muscle is vital for health. The major route to contraction is a rise in intracellular [Ca2+], determined by the entry and efflux of Ca2+ and release and re-uptake into the sarcoplasmic reticulum (SR). We review these processes in myometrium, to better understand excitation-contraction coupling and de...

journal_title：Biological research

authors： Matthew A,Shmygol A,Wray S

更新日期：2004-01-01 00:00:00