Abstract:
:Undifferentiated rat pheochromocytoma PC12 cells were voltage clamped using the whole cell technique. After blockade of outward currents, calcium currents were elicited from -40 and -100 mV. A subpopulation of cells displayed only one current component activated at -10 mV and slowly decaying. In other cells this current coexisted with a component activated around -40 mV and decaying with a faster time constant. We conclude that undifferentiated PC12 cells can express two types of calcium channels, L (long-lasting) and N (neuronal)-type channels.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Janigro D,Maccaferri G,Meldolesi Jdoi
10.1016/0014-5793(89)81131-7subject
Has Abstractpub_date
1989-09-25 00:00:00pages
398-400issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(89)81131-7journal_volume
255pub_type
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