Pretreatment with Assafoetida exerts dose-dependent dual effects on rat hearts.

abstract：BACKGROUND:Annona vepretorum (AV) is a native tree from Caatinga biome (semiarid region of Brazil) popularly known as "araticum" and "pinha da Caatinga." OBJECTIVE:This study was carried out to evaluate the chemical constituents and antioxidant activity (AA) of the essential oil from the leaves from AV (EO-Av) collect...

journal_title：Pharmacognosy magazine

authors： Araújo Cde S,de Oliveira AP,Lima RN,Alves PB,Diniz TC,da Silva Almeida JR

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The plant Launaea procumbens belongs to the family Asteraceae and traditionally used in the treatment rheumatism, kidney, liver dysfunctions and eye diseases. In the present study Phytochemical analysis and fractions of methanolic extract of L. procumbens leaves were tested in vitro for their cytotoxicity. ...

journal_title：Pharmacognosy magazine

authors： Rawat P,Saroj LM,Kumar A,Singh TD,Tewari SK,Pal M

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Aronia melanocarpa (Michx.) Elliot fruits are very rich in polyphenols - procyanidins, flavonoids, and phenolic acids. OBJECTIVE:On rat hepatocytes, isolated by two-stepped collagenase perfusion, we investigated the effect of A. melanocarpa fruit juice (AMFJ) in two models of liver toxicity caused by (i) me...

journal_title：Pharmacognosy magazine

authors： Kondeva-Burdina M,Valcheva-Kuzmanova S,Markova T,Mitcheva M,Belcheva A

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Sophora flavescens Aiton is an important medicinal plant in China. Early in vitro researches of S. flavescens were focused on callus induction and cell suspension culture, only a few were concerned with in vitro multiplication. OBJECTIVE:To establish and optimize the rapid propagation technology of S. flavesce...

journal_title：Pharmacognosy magazine

authors： Kun-Hua W,Shan-Lin G,He-Ping H

更新日期：2010-10-01 00:00:00

abstract：CONTEXT:Recent studies have demonstrated that baicalin has antihyperglycemic effects by inhibiting lipid peroxidation. Baicalin is low hydrophilic and poorly absorbed after oral administration. Thus, a suitable formulation is highly desired to overcome the disadvantages of baicalin. OBJECTIVE:The objective of this wor...

journal_title：Pharmacognosy magazine

authors： Shi F,Wei Z,Zhao Y,Xu X

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Anisomeles malabarica R. Br. (Lamiaceae) is extensively used in traditional medicine in major parts of India for several medicinal purposes, including their use in rheumatism. MATERIALS AND METHODS:The air-dried leaves of A. malabarica were extracted with ethanol, defatted with n-hexane and then successivel...

journal_title：Pharmacognosy magazine

authors： Sudha A,Srinivasan P

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Stryphnodendron adstringens (Mar.) Coville is a native plant from Brazil, rich in phenolic compounds and used on popular medicine as a wound healing agent, in the treatment of gastric lesions and as antimicrobial. MATERIALS AND METHODS:Ultrassound-assisted extraction (UAE) was applied to extraction of epiga...

journal_title：Pharmacognosy magazine

authors： Sousa JN,Pedroso NB,Borges LL,Oliveira GA,Paula JR,Conceição EC

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Plant sterols are the major source of micronutrients and have not shown any obvious side effects in human. β-sitosterol is one of the most prevalent phytosterols which have been recorded in ancient medicinal history for its use in the treatment of many chronic diseases, especially cancer. The modulations of ...

journal_title：Pharmacognosy magazine

authors： Sharmila R,Sindhu G

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Essential oil of Ocimum sanctum Linn. exhibited various pharmacological activities including antifungal and antimicrobial activities. In this study, we analyzed the anticancer and apoptosis mechanisms of Ocimum sanctum essential oil (OSEO). OBJECTIVE:To trigger the apoptosis mechanism in human breast cancer...

journal_title：Pharmacognosy magazine

authors： Manaharan T,Thirugnanasampandan R,Jayakumar R,Kanthimathi MS,Ramya G,Ramnath MG

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Vatica diospyroides type LS is a known source of valuable compounds for cancer treatment, however, in contrast little is known about therapeutic efficacy of type SS. OBJECTIVE:This study focused on in vitro cytotoxicity of these fruit extracts, and the cell death mode they induce in breast cancer cells. MA...

journal_title：Pharmacognosy magazine

authors： Srisawat T,Sukpondma Y,Graidist P,Chimplee S,Kanokwiroon K

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Many diseases are associated with oxidative stress caused by free radicals. The aim of the present study was to evaluate the antidiabetic, antioxidant and antiglycation properties of Eysenhardtia polystachya (EP) bark methanol-water extract. MATERIALS AND METHODS:: The antioxidant capacities were evaluated ...

journal_title：Pharmacognosy magazine

authors： Gutierrez RM,Baez EG

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Microwave-assisted reflux extraction of polysaccharides YPF-P from the famous Chinese traditional drug, Yupingfeng powder, optimization of extracting conditions and evaluation of their antioxidant activity were conducted in this study. RESULTS:Single factor effect trends were achieved through yields and con...

journal_title：Pharmacognosy magazine

authors： Wang D,Zhang BB,Qu XX,Gao F,Yuan MY

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The real mechanism for Thevetia peruviana poisoning remains unclear. Cholinergic activity is important for cardiac function regulation, however, the effect of T. peruviana on cholinergic activity is not well-known. OBJECTIVE:To study the effect of the acute administration of an aqueous extract of the seed k...

journal_title：Pharmacognosy magazine

authors： Marroquín-Segura R,Calvillo-Esparza R,Mora-Guevara JL,Tovalín-Ahumada JH,Aguilar-Contreras A,Hernández-Abad VJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Zataria multiflora Boiss. is a traditional and popular spice in Iran. The effects of 3 ecotypes (ECTPs) of Z. multiflora essential oils (EOs) against most common causes of food-borne and nosocomial infections were evaluated. MATERIALS AND METHODS:The antimicrobial activities of the EOs were examined by brot...

journal_title：Pharmacognosy magazine

authors： Zomorodian K,Saharkhiz MJ,Rahimi MJ,Bandegi A,Shekarkhar G,Bandegani A,Pakshir K,Bazargani A

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The present study examined the pharmacokinetic profiles of two iridoid glycosides named morroniside and loganin in rat plasma after oral administration of crude and processed Cornus officinals. MATERIALS AND METHODS:A rapid, selective and specific high-performance liquid chromatography/electrospray ionizatio...

journal_title：Pharmacognosy magazine

authors： Chen X,Cao G,Jiang J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Rhododendron is a group of famous landscape plants with high medicinal value. However, there is no simple or universal manner to discriminate the various species of this group. Deoxyribonucleic acid (DNA) barcoding technique is a new biological tool that can accurately and objectively identify species by usi...

journal_title：Pharmacognosy magazine

authors： Liu Y,Zhang L,Liu Z,Luo K,Chen S,Chen K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Haberlea rhodopensis Friv. (Gesneriaceae) is a rare poikilohydric endemic and preglacial relict growing in Balkan Peninsula. Previous investigations demonstrated strong antioxidant, antimicrobial and antimutagenic potential of alcoholic extract from the plant. OBJECTIVE:The isolation of known caffeoyl pheny...

journal_title：Pharmacognosy magazine

authors： Kondeva-Burdina M,Zheleva-Dimitrova D,Nedialkov P,Girreser U,Mitcheva M

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Polygonum multiflorum is an important medicinal plant. Hairy roots systems obtained by transforming plant tissues with the natural genetic engineer Agrobacterium rhizogenes can produce valuable biological active substances, which have immense potential in the pharmaceutical industry. OBJECTIVE:To optimize t...

journal_title：Pharmacognosy magazine

authors： Huang B,Lin H,Yan C,Qiu H,Qiu L,Yu R

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To optimization of extraction of antioxidant compounds from guava (Psidium guajava L.) leaves and showed that the guava leaves are the potential source of antioxidant compounds. MATERIALS AND METHODS:The bioactive polysaccharide compounds of guava leaves (P. guajava L.) were obtained using ultrasonic-assiste...

journal_title：Pharmacognosy magazine

authors： Kong F,Yu S,Feng Z,Wu X

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Mimosa caesalpiniifolia Benth. (Leguminosae) is widely found in the Brazilian Northeast region and markedly contributes to production of pollen and honey, being considered an important honey plant in this region. OBJECTIVE:To investigate the chemical composition of the ethanol extract of leaves from M. caes...

journal_title：Pharmacognosy magazine

authors： Monção NB,Costa LM,Arcanjo DD,Araújo BQ,Lustosa Mdo C,Rodrigues KA,Carvalho FA,Costa AP,Lopes Citó AM

更新日期：2014-08-01 00:00:00

abstract：:The present study was undertaken with the objective of finding out the comparative analgesic effect of Ligusticum chuanxiong (LC) pieces decoction, LC formula granule decoction, liquored LC pieces decoction and liquored LC formula granule decoction. The analgesic effects were analyzed using the hot plate and acetic-in...

journal_title：Pharmacognosy magazine

authors： Gao D,Xu L

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:It is known that when crude Pinelliae rhizome and Pinelliae rhizoma preparatum are combined with Aconiti Radix Cocta respectively, the toxicity of the combination varies. However, the component's transformation between different compatibility have remained unclear. OBJECTIVE:In this paper, a novel approach ...

journal_title：Pharmacognosy magazine

authors： Wang Y,Li Y,Zhang X,Xu Y,Wang H,Zhang Y

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Methyl protodioscin (MPD) is a furostanol bisglycoside with antitumor properties. It has been shown to reduce proliferation, cause cell cycle arrest. OBJECTIVE:The present study elucidates the mechanism underlying MPD's apoptotic effects, using the A549 human lung cancer cell line. MATERIALS AND METHODS:Th...

journal_title：Pharmacognosy magazine

authors： Bai Y,Qu XY,Yin JQ,Wu L,Jiang H,Long HW,Jia Q

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Hakea sericea Schrader is an invasive shrub in Portuguese forests. OBJECTIVE:The goal of this work was to evaluate the antimicrobial activity of H. sericea extracts against several strains of microorganisms, including the ability to inhibit the formation of biofilms. Additionally the cytotoxic properties of...

journal_title：Pharmacognosy magazine

authors： Luís A,Breitenfeld L,Ferreira S,Duarte AP,Domingues F

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Coffea canephora is the commonly cultivated coffee species in the world along with Coffea arabica. Different pests and pathogens affect the production and quality of the coffee. Jasmonic acid (JA) is a plant hormone which plays an important role in plants growth, development, and defense mechanisms, particul...

journal_title：Pharmacognosy magazine

authors： Bharathi K,Sreenath HL

更新日期：2017-07-01 00:00:00

abstract：Introduction:Melanin is synthesized by melanocytes, which are located in the basal layer of the skin. After synthesis, melanin is further deposited on the surface of the skin to form black spots or chloasma. Tyrosinase is a rate-limiting enzyme that plays an important role in melanogenesis. Currently, there are many dr...

journal_title：Pharmacognosy magazine

authors： Hong JH,Chen HJ,Xiang SJ,Cao SW,An BC,Ruan SF,Zhang B,Weng LD,Zhu HX,Liu Q

更新日期：2018-01-01 00:00:00

abstract：:Mentha piperita essential oil was bactericidal in order of E. coli> S. aureus > Pseudomonas aeruginosa > S. faecalis > Klebsiella pneumoniae. The oil with total phenolics of 89.43 ± 0.58 µg GAE/mg had 63.82 ± 0.05% DPPH inhibition activity with an IC (50) = 3.9 µg/ml. Lipid peroxidation inhibition was comparable to BH...

journal_title：Pharmacognosy magazine

authors： Sharafi SM,Rasooli I,Owlia P,Taghizadeh M,Astaneh SD

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Zingiber officinale Rosc. is not only an important medical plant in China, but also one of the most commonly used plant spices around the world. Early researches in Z. officinale Rosc. were focused on rapid propagation, germplasm preservation, and somatic embryogenesis, only a few reports focused on the gene...

journal_title：Pharmacognosy magazine

authors： Kun-Hua W,Jian-Hua M,He-Ping H,Shan-Lin G

更新日期：2011-07-01 00:00:00

abstract：Background:Meyna spinosa (M.S) (Roxb.) ex Link and Oroxylum indicum (O.I) (Linn.) Vent, widely used traditional Northeast Indian medicinal plant used for various purposes, have not yet explored for safety profile. Objective:To investigate the safety profile of M.S (Roxb.) ex Link leaves and O.I (Linn.) Vent stem bark ...

journal_title：Pharmacognosy magazine

authors： Singh S,Chattopadhyay P,Borthakur SK,Policegoudra R

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Lavatera cretica L. was used in folk medicine as anti-inflammatory among other applications. As inflammation is many times associated with oxidative processes, the aim of the present work was to evaluate the ability of aqueous extracts obtained from different parts of L. cretica to prevent oxidation or infla...

journal_title：Pharmacognosy magazine

authors： Ben-Nasr S,Aazza S,Mnif W,Miguel Mda G

更新日期：2015-01-01 00:00:00