Comparison of pharmacokinetic behavior of two iridoid glycosides in rat plasma after oral administration of crude Cornus officinals and its jiuzhipin by high performance liquid chromatography triple quadrupole mass spectrometry combined with multiple reac

abstract：BACKGROUND:The real mechanism for Thevetia peruviana poisoning remains unclear. Cholinergic activity is important for cardiac function regulation, however, the effect of T. peruviana on cholinergic activity is not well-known. OBJECTIVE:To study the effect of the acute administration of an aqueous extract of the seed k...

journal_title：Pharmacognosy magazine

authors： Marroquín-Segura R,Calvillo-Esparza R,Mora-Guevara JL,Tovalín-Ahumada JH,Aguilar-Contreras A,Hernández-Abad VJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The present study reports and compares the results of Gas Chromatographic-Mass analyses of Pulicaria jaubertii leaf (P-1) and root (P-2) essential oils, as well as their in vitro antimicrobial and cytotoxic activities. MATERIALS AND METHODS:The chemical composition of P-1 and P-2 essential oils of P. jauber...

journal_title：Pharmacognosy magazine

authors： Fawzy GA,Al Ati HY,El Gamal AA

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Blechnum orientale Linn. (Blechnaceae), a fern, is traditionally used in the treatment of various ailments, such as skin diseases, stomach pain, urinary bladder complaints, and also as a female contraceptive. Previously, we reported a strong radical scavenging activity, antibacterial activity and cytotoxicit...

journal_title：Pharmacognosy magazine

authors： Lai HY,Lim YY,Kim KH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is one of the leading chronic diseases worldwide. In patients with poor glycemic control, high blood glucose level may lead to other life-threatening complications. Pandanus amaryllifolius Roxb. (PA) leaves are used in traditional medicine for the treatment of diabetes. OBJECTIVE:This stud...

journal_title：Pharmacognosy magazine

authors： Chiabchalard A,Nooron N

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:Although many studies displayed the favorable effects of Assafoetida, some of them reported that high doses of Assafoetida could lead to harmful effects. AIMS:In this study, the effect of pretreatment with Assafoetida investigated on ischemic-reperfusion injury in isolated rat heart model. MATERIALS AND METHO...

journal_title：Pharmacognosy magazine

authors： Esmailidehaj M,Kakoo M,Rezvani ME,Mosaddeghmehrjardi MH

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Mimosa caesalpiniifolia Benth. (Leguminosae) is widely found in the Brazilian Northeast region and markedly contributes to production of pollen and honey, being considered an important honey plant in this region. OBJECTIVE:To investigate the chemical composition of the ethanol extract of leaves from M. caes...

journal_title：Pharmacognosy magazine

authors： Monção NB,Costa LM,Arcanjo DD,Araújo BQ,Lustosa Mdo C,Rodrigues KA,Carvalho FA,Costa AP,Lopes Citó AM

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Polygonum multiflorum is an important medicinal plant. Hairy roots systems obtained by transforming plant tissues with the natural genetic engineer Agrobacterium rhizogenes can produce valuable biological active substances, which have immense potential in the pharmaceutical industry. OBJECTIVE:To optimize t...

journal_title：Pharmacognosy magazine

authors： Huang B,Lin H,Yan C,Qiu H,Qiu L,Yu R

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Lavatera cretica L. was used in folk medicine as anti-inflammatory among other applications. As inflammation is many times associated with oxidative processes, the aim of the present work was to evaluate the ability of aqueous extracts obtained from different parts of L. cretica to prevent oxidation or infla...

journal_title：Pharmacognosy magazine

authors： Ben-Nasr S,Aazza S,Mnif W,Miguel Mda G

更新日期：2015-01-01 00:00:00

abstract：Background:Gelatinous Chinese medicines (GCMs) including Asini Corii Colla, Testudinis Carapacis ET Plastri Colla, and Cervi Cornus Colla, were made from reptile shell or mammalian skin or deer horn, and consumed as a popular tonic, as well as hemopoietic and hemostatic agents. Misuse of them would not exert their func...

journal_title：Pharmacognosy magazine

authors： Yang H,Zheng J,Wang HY,Li N,Yang YY,Shen YP

更新日期：2017-10-01 00:00:00

abstract：Background:Withania somnifera is a medicinal plant native to India and is known to have anticancer properties. It has been investigated for its anti-melanoma properties, and since melanoma presents on the skin, it is prudent to probe the use of W. somnifera in topical formulations. To enhance topical drug delivery and ...

journal_title：Pharmacognosy magazine

authors： Chinembiri TN,Gerber M,du Plessis LH,du Preez JL,Hamman JH,du Plessis J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Traditionally, a number of medicinal plants are used to treat various types of hepatic disorders but few of them were pharmacologically evaluated for their safety and efficacy. The combination of Andrographis paniculata (Kalmegha), Tinospora cordifolia (Guduchi), and Solanum nigrum (Kakmachi) was traditional...

journal_title：Pharmacognosy magazine

authors： Singh DP,Awasthi H,Luqman S,Singh S,Mani D

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Pogostemonis Herba, the dried aerial part of Pogostemon cablin Blanco, is a well-known materia medica in Asia that is widely used for syndrome of gastrointestinal dysfunctions. OBJECTIVE:This study was undertaken to examine whether Pogostemon cablin extract (PCe) might have any beneficial effect on hypoxia ...

journal_title：Pharmacognosy magazine

authors： Lim CY,Kim BY,Lim SH,Cho SI

更新日期：2015-04-01 00:00:00

abstract：Objective:Wine grape sap or bleeding sap of grapes (GBS) is commonly used in Xinjiang (China) for therapeutic aims. Do variations in composition related to region and variety affect its properties? Methods:GBS samples originating in various parts of Xinjiang (Turpan, Hotan, Kashgar, and Atush) were tested for phenols ...

journal_title：Pharmacognosy magazine

authors： Le L,Umar A,Iburaim A,Moore N

更新日期：2017-10-01 00:00:00

abstract：CONTEXT:Scyphiphora hydrophyllacea is a shrub mangrove plant of the family Rubiaceae and not yet been studied for anti-hepatocarcinogenic effects. OBJECTIVES:We investigated possible in vitro anti-hepatocarcinogenic and antioxidant properties of S. hydrophyllacea. MATERIALS AND METHODS:Dried leaves of S. hydrophyllac...

journal_title：Pharmacognosy magazine

authors： Samarakoon SR,Shanmuganathan C,Ediriweera MK,Piyathilaka P,Tennekoon KH,Thabrew I,Galhena P,De Silva ED

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Sophora flavescens Aiton is an important medicinal plant in China. Early in vitro researches of S. flavescens were focused on callus induction and cell suspension culture, only a few were concerned with in vitro multiplication. OBJECTIVE:To establish and optimize the rapid propagation technology of S. flavesce...

journal_title：Pharmacognosy magazine

authors： Kun-Hua W,Shan-Lin G,He-Ping H

更新日期：2010-10-01 00:00:00

abstract：Background:Bacopa monnieri (BM) is a herbaceous plant traditionally used from time immemorial in Ayurvedic and folklore medicines. We hypothesized that the extract of the whole plant might contain numerous molecules with having antitumor activities that could be very effective in killing of human cancer cells. Objecti...

journal_title：Pharmacognosy magazine

authors： Mallick MN,Khan W,Parveen R,Ahmad S,Sadaf,Najm MZ,Ahmad I,Husain SA

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Anisomeles malabarica R. Br. (Lamiaceae) is extensively used in traditional medicine in major parts of India for several medicinal purposes, including their use in rheumatism. MATERIALS AND METHODS:The air-dried leaves of A. malabarica were extracted with ethanol, defatted with n-hexane and then successivel...

journal_title：Pharmacognosy magazine

authors： Sudha A,Srinivasan P

更新日期：2014-08-01 00:00:00

abstract：Background:Enterococcus faecalis (Ef) is a multidrug-resistant pathogenic bacteria associated with hospital-acquired infections. Ef is involved in a number of infectious diseases. It generally infects patients with the weekend immune system, i.e. a person mostly acquires Ef infections in the hospital, especially in int...

journal_title：Pharmacognosy magazine

authors： Katva S,Das S,Moti HS,Jyoti A,Kaushik S

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Coffea canephora is the commonly cultivated coffee species in the world along with Coffea arabica. Different pests and pathogens affect the production and quality of the coffee. Jasmonic acid (JA) is a plant hormone which plays an important role in plants growth, development, and defense mechanisms, particul...

journal_title：Pharmacognosy magazine

authors： Bharathi K,Sreenath HL

更新日期：2017-07-01 00:00:00

abstract：:The present study was undertaken with the objective of finding out the comparative analgesic effect of Ligusticum chuanxiong (LC) pieces decoction, LC formula granule decoction, liquored LC pieces decoction and liquored LC formula granule decoction. The analgesic effects were analyzed using the hot plate and acetic-in...

journal_title：Pharmacognosy magazine

authors： Gao D,Xu L

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Jaeumganghwa-tang (JEGH) is a traditional Korean herbal medicine for the treatment of chronic bronchitis, nephritis and diabetes mellitus. OBJECTIVE:A high performance liquid chromatography-diode array detector (HPLC-DAD) method was developed for simultaneous determination of 11 major compounds such as 5- h...

journal_title：Pharmacognosy magazine

authors： Yun BR,Weon JB,Lee J,Eom MR,Ma CJ

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Many diseases are associated with oxidative stress caused by free radicals. The aim of the present study was to evaluate the antidiabetic, antioxidant and antiglycation properties of Eysenhardtia polystachya (EP) bark methanol-water extract. MATERIALS AND METHODS:: The antioxidant capacities were evaluated ...

journal_title：Pharmacognosy magazine

authors： Gutierrez RM,Baez EG

更新日期：2014-04-01 00:00:00

abstract：Background:Hawthorn (Crataegus pinnatifida) fruit has enjoyed a great popularity as a pleasant-tasting food associated with hypolipidemic and antioxidant effects. Objective:Our aim was to screen the effective fraction of hawthorn fruit in the treatment of hyperlipidemia rats. Materials and Methods: In this study, etha...

journal_title：Pharmacognosy magazine

authors： Shao F,Gu L,Chen H,Liu R,Huang H,Chen L,Yang M

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Recently, many efforts have been made to discover new products of natural origin which can limit the xenobiotic-induced hepatic injury. Carbon tetrachloride (CCl4) is a highly toxic chemical that is widely used to study hepatotoxicity in animal models. OBJECTIVE:The present study was conducted to investigat...

journal_title：Pharmacognosy magazine

authors： Abdou RH,Saleh SY,Khalil WF

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:Recent studies have demonstrated that baicalin has antihyperglycemic effects by inhibiting lipid peroxidation. Baicalin is low hydrophilic and poorly absorbed after oral administration. Thus, a suitable formulation is highly desired to overcome the disadvantages of baicalin. OBJECTIVE:The objective of this wor...

journal_title：Pharmacognosy magazine

authors： Shi F,Wei Z,Zhao Y,Xu X

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Methyl protodioscin (MPD) is a furostanol bisglycoside with antitumor properties. It has been shown to reduce proliferation, cause cell cycle arrest. OBJECTIVE:The present study elucidates the mechanism underlying MPD's apoptotic effects, using the A549 human lung cancer cell line. MATERIALS AND METHODS:Th...

journal_title：Pharmacognosy magazine

authors： Bai Y,Qu XY,Yin JQ,Wu L,Jiang H,Long HW,Jia Q

更新日期：2014-07-01 00:00:00

abstract：CONTEXT:It was found that the essential oil of Acorus calamus rhizomes showed insecticidal activity. AIM:The aim of this study was to determine the chemical composition of the essential oil from A. calamus rhizomes, evaluate insecticidal and repellant activity against Lasioderma serricorne (LS) and Tribolium castaneum...

journal_title：Pharmacognosy magazine

authors： Chen HP,Yang K,Zheng LS,You CX,Cai Q,Wang CF

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Manilkara subsericea (Sapotaceae) is a species widely spread in the sandbanks of Restinga de Jurubatiba National Park (Rio de Janeiro, Brazil). It is commonly known as "maçaranduba", "maçarandubinha" and "guracica", being used in this locality as food, and timber. However, M. subsericea remains almost unexpl...

journal_title：Pharmacognosy magazine

authors： de Almeida FB,Fernandes CP,Romao W,Vanini G,Costa HB,França HS,Santos MG,Carvalho JC,Falcão DQ,Rocha L

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Plant sterols are the major source of micronutrients and have not shown any obvious side effects in human. β-sitosterol is one of the most prevalent phytosterols which have been recorded in ancient medicinal history for its use in the treatment of many chronic diseases, especially cancer. The modulations of ...

journal_title：Pharmacognosy magazine

authors： Sharmila R,Sindhu G

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The plant Launaea procumbens belongs to the family Asteraceae and traditionally used in the treatment rheumatism, kidney, liver dysfunctions and eye diseases. In the present study Phytochemical analysis and fractions of methanolic extract of L. procumbens leaves were tested in vitro for their cytotoxicity. ...

journal_title：Pharmacognosy magazine

authors： Rawat P,Saroj LM,Kumar A,Singh TD,Tewari SK,Pal M

更新日期：2016-07-01 00:00:00