Methyl protodioscin induces G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells.

abstract：Background:Chemical fungicides are widely used to control crop diseases, but these chemicals have adverse effects. They destroy the ecological environment and even have toxic effects on human beings. In this context, the development of botanical pesticides is relevant. One potential botanical pesticide is chelerythrine...

journal_title：Pharmacognosy magazine

authors： Wei Q,Zhao M,Li X

更新日期：2017-10-01 00:00:00

abstract：Background:Bacopa monnieri (BM) is a herbaceous plant traditionally used from time immemorial in Ayurvedic and folklore medicines. We hypothesized that the extract of the whole plant might contain numerous molecules with having antitumor activities that could be very effective in killing of human cancer cells. Objecti...

journal_title：Pharmacognosy magazine

authors： Mallick MN,Khan W,Parveen R,Ahmad S,Sadaf,Najm MZ,Ahmad I,Husain SA

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Caries and periodontal diseases remain as important diseases in the Brazilian population. One important pathogen associated with this situation is Streptococcus mutans and other important factor is this pathogen's ability to adhere firmly to the tooth surface leading to dental biofilm formation and caries de...

journal_title：Pharmacognosy magazine

authors： de Sousa MB,Júnior JO,Barbosa WL,da Silva Valério E,da Mata Lima A,de Araújo MH,Muzitano MF,Nakamura CV,de Mello JC,Teixeira FM

更新日期：2016-05-01 00:00:00

abstract：:In this work, the chemical constituents, antibacterial and modulatory activities of the essential oil of Lantana camara Linn were studied. The essential oil was extracted from the leaves of L. camara by hydrodistillation method using Clevenger's apparatus and its chemical constituents were separated and identified by ...

journal_title：Pharmacognosy magazine

authors： Sousa EO,Silva NF,Rodrigues FF,Campos AR,Lima SG,Costa JG

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The present study reports and compares the results of Gas Chromatographic-Mass analyses of Pulicaria jaubertii leaf (P-1) and root (P-2) essential oils, as well as their in vitro antimicrobial and cytotoxic activities. MATERIALS AND METHODS:The chemical composition of P-1 and P-2 essential oils of P. jauber...

journal_title：Pharmacognosy magazine

authors： Fawzy GA,Al Ati HY,El Gamal AA

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Rhododendron is a group of famous landscape plants with high medicinal value. However, there is no simple or universal manner to discriminate the various species of this group. Deoxyribonucleic acid (DNA) barcoding technique is a new biological tool that can accurately and objectively identify species by usi...

journal_title：Pharmacognosy magazine

authors： Liu Y,Zhang L,Liu Z,Luo K,Chen S,Chen K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Tephrosia purpurea is an Indian herb used in traditional medicine to treat various diseases such as jaundice, asthma, liver and urinary disorders. However, the anti-cancer potential of T. purpurea on hepatocellular carcinoma (HCC) is poorly understood. Therefore, this study aims to investigate the anti-cance...

journal_title：Pharmacognosy magazine

authors： Padmapriya R,Gayathri L,Ronsard L,Akbarsha MA,Raveendran R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:A Korean herbal medicine, KOTMIN13, composed of Inula japonica Thunberg, Trichosanthes kirilowii Maximowicz var. japonica kitamura, Peucedanum praeruptorum Dunn, and Allium macrostemon Bge, has been used for anti-allergic and anti-asthmatic treatment in oriental clinics, but its activity has not been investi...

journal_title：Pharmacognosy magazine

authors： Lee E,Kim SG,Park NY,Park HH,Jeong KT,Choi J,Lee IH,Lee H,Lee E

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Gegenqinlian decoction (GQD) is a famous traditional medicine recipe. It is composed of four herbs including Radix Puerariae (GG), Radix Scutellariae (HQ), Rhizoma Coptidis (HL) and Radix Glycyrrhizae (GC), which is widely used for treating gastro-intestinal disorders in the clinical practice of Traditional ...

journal_title：Pharmacognosy magazine

authors： Zhang Y,Yuan J,Wang Y,Wang Y,An R,Wang X

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Polygonum multiflorum is an important medicinal plant. Hairy roots systems obtained by transforming plant tissues with the natural genetic engineer Agrobacterium rhizogenes can produce valuable biological active substances, which have immense potential in the pharmaceutical industry. OBJECTIVE:To optimize t...

journal_title：Pharmacognosy magazine

authors： Huang B,Lin H,Yan C,Qiu H,Qiu L,Yu R

更新日期：2014-01-01 00:00:00

abstract：AIMS:The study is conducted to evaluate the immunomodulatory, cytotoxicity, and antioxidant potential of Ziziphus mauritiana (Rhamnaceae). Phytochemical analysis of Z. mauritiana revealed the presence of alkaloids, anthraquinone glycoside, cardiac glycoside, saponin, tannin, and flavonoids. METHODOLOGY:The cytotoxicit...

journal_title：Pharmacognosy magazine

authors： Afzal S,Batool M,Ch BA,Ahmad A,Uzair M,Afzal K

更新日期：2017-07-01 00:00:00

abstract：Background:Hypertension is a great global health challenge and it mostly requires drug combination therapy with the various advantages. Metoprolol (MP) and paeoniflorin are both commonly used for the treatment of hypertension. However, whether they exert synergistic effects on antihypertension or not remains unclear, e...

journal_title：Pharmacognosy magazine

authors： Li B,Yang ZB,Lei SS,Su J,Jin ZW,Chen SH,Lv GY

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Abelmoschus esculentus L. is a healthy vegetable belonging to the family Malvaceae. This article reports the contents of total phenolics (TP) and total flavonoids (TF) in 80% methanol extracts of the flower (FL), fruit (FR), leaf (L), and seed (S) of A. esculentus, and in 0, 10, 30, 50, and 70% methanol elua...

journal_title：Pharmacognosy magazine

authors： Liao H,Dong W,Shi X,Liu H,Yuan K

更新日期：2012-04-01 00:00:00

abstract：Background:At present, approximately 17-25 million people in the world suffer from Alzheimer's disease (AD). The most efficacious and acceptable therapeutic drug clinically are the acetylcholinesterase inhibitors (AChEIs). Yinhuang oral liquid is a Chinese medicine preparation which contains AChEIs according to the lit...

journal_title：Pharmacognosy magazine

authors： Zhang H,Guo Y,Meng L,Sun H,Yang Y,Gao Y,Sun J

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Manilkara subsericea (Sapotaceae) is a species widely spread in the sandbanks of Restinga de Jurubatiba National Park (Rio de Janeiro, Brazil). It is commonly known as "maçaranduba", "maçarandubinha" and "guracica", being used in this locality as food, and timber. However, M. subsericea remains almost unexpl...

journal_title：Pharmacognosy magazine

authors： de Almeida FB,Fernandes CP,Romao W,Vanini G,Costa HB,França HS,Santos MG,Carvalho JC,Falcão DQ,Rocha L

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Inula helenium, which belongs to thecomposite family, is an important crude drug in traditional Chinese medicine. MATERIALS AND METHODS:The effects of ethanol concentration, liquid to solid ratio, extraction temperature, and duration of microwave irradiation on the flavonoid extraction yield were studied th...

journal_title：Pharmacognosy magazine

authors： Guo CY,Wang J,Hou Y,Zhao YM,Shen LX,Zhang DS

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Annona vepretorum (AV) is a native tree from Caatinga biome (semiarid region of Brazil) popularly known as "araticum" and "pinha da Caatinga." OBJECTIVE:This study was carried out to evaluate the chemical constituents and antioxidant activity (AA) of the essential oil from the leaves from AV (EO-Av) collect...

journal_title：Pharmacognosy magazine

authors： Araújo Cde S,de Oliveira AP,Lima RN,Alves PB,Diniz TC,da Silva Almeida JR

更新日期：2015-07-01 00:00:00

abstract：Introduction:In the present work, the method to extract, isolate, and characterize orange peel pectin using soxhlation, and thereafter, the use of this polymer-polymer in the formulation of fast dispersable and slow-releasing tablet has been studied. Thereafter, the evaluation and comparison of fast dispersible/slow-re...

journal_title：Pharmacognosy magazine

authors： Srivastava P,Singh M,Bhargava S

更新日期：2017-10-01 00:00:00

abstract：Background:Withania somnifera is a medicinal plant native to India and is known to have anticancer properties. It has been investigated for its anti-melanoma properties, and since melanoma presents on the skin, it is prudent to probe the use of W. somnifera in topical formulations. To enhance topical drug delivery and ...

journal_title：Pharmacognosy magazine

authors： Chinembiri TN,Gerber M,du Plessis LH,du Preez JL,Hamman JH,du Plessis J

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:The present study examined the pharmacokinetic profiles of two iridoid glycosides named morroniside and loganin in rat plasma after oral administration of crude and processed Cornus officinals. MATERIALS AND METHODS:A rapid, selective and specific high-performance liquid chromatography/electrospray ionizatio...

journal_title：Pharmacognosy magazine

authors： Chen X,Cao G,Jiang J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The active ingredients and thus pharmacological efficacy of traditional Chinese medicine (TCM) at different degrees of parching process vary greatly. OBJECTIVE:Near-infrared spectroscopy (NIR) was used to develop a new method for rapid online analysis of TCM parching process, using two kinds of chemical ind...

journal_title：Pharmacognosy magazine

authors： Li K,Wang W,Liu Y,Jiang S,Huang G,Ye L

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Grapes and their products are known to have been used for the treatment of diseases throughout history. OBJECTIVE:It was aimed to investigate the effects of Erzincan Cimin grapes on an organism model of Caenorhabditis elegans N2 wild type and C. elegans BS913 strains with gonad cancer. MATERIALS AND METHOD...

journal_title：Pharmacognosy magazine

authors： Ozpinar H,Ozpinar N,Karakus S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The androgen comprises a group of hormones that play roles in male reproductive activity as well as personal characteristics. OBJECTIVE:We investigated the androgenic activity of various herbal medicines in human prostate cancer 22Rv1 cells. MATERIALS AND METHODS:Herbal extracts of Trichosanthes kirilowii ...

journal_title：Pharmacognosy magazine

authors： Jeong SJ,Choi JY,Dong MS,Seo CS,Shin HK

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Yinqiaosan (Lonicerae and Forsythiae Powder), as a famous prescription of Dr. Wu Jutong in Qing dynasty of China, has the effects of diaphoresis cooling, fire-purging, and detoxicaton. It is mainly used in the treatment of influenza, hand-foot-mouth disease, esophagitis, pneumonia, acute tonsillitis, mumps, ...

journal_title：Pharmacognosy magazine

authors： Shu Y,Chen Y,Qin K,Liu X,Cai B

更新日期：2016-04-01 00:00:00

abstract：:Alcohol addiction is a worldwide problem. It has mainly two components: dependence and withdrawal. Characteristic properties of most anti-addictive compounds include anti-anxiety, anticonvulsant, antidepressant, and nootropic actions. Shankhpushpi (Convolvulus pluricaulis. Convolvulaceae), known ethnopharmacologically...

journal_title：Pharmacognosy magazine

authors： Heba M,Faraz S,Banerjee S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Rhizoma dioscoreae nipponicae is a perennial herb and its roots have been widely used in Traditional Chinese Medicine (TCM). OBJECTIVE:To develop and optimize the extraction and hydrolysis technology of diosgenin from Rhizoma dioscoreae nipponicae. MATERIALS AND METHODS:1-methyl-3-(3-sulfopropyl)-imidazoli...

journal_title：Pharmacognosy magazine

authors： Yan W,Ji L,Hang S,Shun Y

更新日期：2013-07-01 00:00:00

abstract：Background:Asparagus adscendens Roxb. (Asparagaceae), is native to the Himalayas. This plant has been used in the prevention and effective treatment of various forms of cancers. Objective:This paper reports, for the first time, on the cytotoxicity of the methanol (MeOH) extract of the roots of A. adscendens and its so...

journal_title：Pharmacognosy magazine

authors： Khan KM,Nahar L,Mannan A,Arfan M,Khan GA,Al-Groshi A,Evans A,Dempster NM,Ismail FMD,Sarker SD

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Platycodi radix, the dried root of Platycodon grandiflorum A. DC, has been widely used as food and herb medicine for treating cough, cold and other respiratory ailments, and platycodin D (PD) is one of the most important compounds in Platycodi Radix. OBJECTIVE:The purpose of this study was to compare the ph...

journal_title：Pharmacognosy magazine

authors： Shan J,Zou J,Xie T,Kang A,Zhou W,Deng H,Mao Y,Di L,Wang S

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Lavatera cretica L. was used in folk medicine as anti-inflammatory among other applications. As inflammation is many times associated with oxidative processes, the aim of the present work was to evaluate the ability of aqueous extracts obtained from different parts of L. cretica to prevent oxidation or infla...

journal_title：Pharmacognosy magazine

authors： Ben-Nasr S,Aazza S,Mnif W,Miguel Mda G

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Sesquiterpenoids, such as tussilagone, has effects of raising blood pressure, antiplatelet aggregation, and anti-inflammation activities, which is regarded as index compound for quality control of Tussilago farfara L. OBJECTIVE:This study was aimed to obtain an effective method for fast isolation of sesquit...

journal_title：Pharmacognosy magazine

authors： Cao K,Xu Y,Zhao TM,Zhang Q

更新日期：2016-10-01 00:00:00