Abstract：
BACKGROUND:Manilkara subsericea (Sapotaceae) is a species widely spread in the sandbanks of Restinga de Jurubatiba National Park (Rio de Janeiro, Brazil). It is commonly known as "maçaranduba", "maçarandubinha" and "guracica", being used in this locality as food, and timber. However, M. subsericea remains almost unexplored regarding its chemical constituents, including secondary metabolites from the leaves. OBJECTIVE:Identify the chemical constituents from the leaves of M. subsericea. MATERIALS AND METHODS:Leaves were macerated with ethanol (96% v/v), and dried crude ethanolic extract was sequentially washed with the organic solvents in order to obtain an ethyl acetate fraction. Substances from this fraction were identified by different techniques, such as negative-ion electrospray ionization Fourier and (1)H and (13)C nuclear magnetic resonance (NMR). Fresh leaves from M. subsericea were also submitted to hydrodistillation in order to obtain volatile substances, which were identified by gas chromatograph coupled to mass spectrometer. RESULTS:NMR(1)H and (13)C spectra allowed for the identification of the compounds myricetin, quercetin, and kaempferol from the ethyl acetate fraction. The negative-ion electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry mass spectrum also revealed the presence in this fraction of a polyhydroxytriterpene acid (pomolic acid), and some flavonoids, such as quercitrin, and myricitrin. In all 34 volatile compounds were identified by gas chromatography-mass spectrometry, including monoterpenes, sesquiterpenes, and long chain hydrocarbons. CONCLUSION:This study describes the first reports concerning the phytochemical information about leaves from M. subsericea. SUMMARY:Manilkara subsericea fruits proved to be a rich source of triterpenes. However, no phytochemical studies were carried out with leaves. Thus, we described identification of volatile substances from its essential oils, in addition to non-reported triterpene and flavonoids from this species.
journal_name
Pharmacogn Magjournal_title
Pharmacognosy magazineauthors
de Almeida FB,Fernandes CP,Romao W,Vanini G,Costa HB,França HS,Santos MG,Carvalho JC,Falcão DQ,Rocha Ldoi
10.4103/0973-1296.172957subject
Has Abstractpub_date
2015-10-01 00:00:00pages
S533-7issue
Suppl 4eissn
0973-1296issn
0976-4062pii
PM-11-533journal_volume
11pub_type
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