Safety Profile Investigations of Meyna spinosa (Roxb.) and Oroxylum indicum (Linn.) Extracts Collected from Northeast India.

abstract：BACKGROUND:Grapes and their products are known to have been used for the treatment of diseases throughout history. OBJECTIVE:It was aimed to investigate the effects of Erzincan Cimin grapes on an organism model of Caenorhabditis elegans N2 wild type and C. elegans BS913 strains with gonad cancer. MATERIALS AND METHOD...

journal_title：Pharmacognosy magazine

authors： Ozpinar H,Ozpinar N,Karakus S

更新日期：2017-07-01 00:00:00

abstract：CONTEXT:Recent studies have demonstrated that baicalin has antihyperglycemic effects by inhibiting lipid peroxidation. Baicalin is low hydrophilic and poorly absorbed after oral administration. Thus, a suitable formulation is highly desired to overcome the disadvantages of baicalin. OBJECTIVE:The objective of this wor...

journal_title：Pharmacognosy magazine

authors： Shi F,Wei Z,Zhao Y,Xu X

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Annona vepretorum (AV) is a native tree from Caatinga biome (semiarid region of Brazil) popularly known as "araticum" and "pinha da Caatinga." OBJECTIVE:This study was carried out to evaluate the chemical constituents and antioxidant activity (AA) of the essential oil from the leaves from AV (EO-Av) collect...

journal_title：Pharmacognosy magazine

authors： Araújo Cde S,de Oliveira AP,Lima RN,Alves PB,Diniz TC,da Silva Almeida JR

更新日期：2015-07-01 00:00:00

abstract：:The hexane, ethylacetate and methanol extracts from Bauhinia tomentosa and Bauhinia vahlii roots were tested for their antimicrobial activity against Gram-positive bacteria (four strains), Gram-negative bacteria (three strains) and three fungi strains using microdilution methods, for the determination of minimal inhib...

journal_title：Pharmacognosy magazine

authors： Dugasani S,Balijepalli MK,Tandra S,Pichika MR

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Essential oil of Ocimum sanctum Linn. exhibited various pharmacological activities including antifungal and antimicrobial activities. In this study, we analyzed the anticancer and apoptosis mechanisms of Ocimum sanctum essential oil (OSEO). OBJECTIVE:To trigger the apoptosis mechanism in human breast cancer...

journal_title：Pharmacognosy magazine

authors： Manaharan T,Thirugnanasampandan R,Jayakumar R,Kanthimathi MS,Ramya G,Ramnath MG

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Platycodi radix, the dried root of Platycodon grandiflorum A. DC, has been widely used as food and herb medicine for treating cough, cold and other respiratory ailments, and platycodin D (PD) is one of the most important compounds in Platycodi Radix. OBJECTIVE:The purpose of this study was to compare the ph...

journal_title：Pharmacognosy magazine

authors： Shan J,Zou J,Xie T,Kang A,Zhou W,Deng H,Mao Y,Di L,Wang S

更新日期：2015-10-01 00:00:00

abstract：Background:Moringa oleifera (MO), commonly known as the drumstick tree, is used in folklore medicine for the treatment of skin disease. Objective:The objective of this study is to evaluate the ethyl acetate (EtOAc) fraction of MO leaves for in vitro antibacterial, antioxidant, and wound healing activities and conduct ...

journal_title：Pharmacognosy magazine

authors： Gothai S,Muniandy K,Zarin MA,Sean TW,Kumar SS,Munusamy MA,Fakurazi S,Arulselvan P

更新日期：2017-10-01 00:00:00

abstract：Background:Chemical fungicides are widely used to control crop diseases, but these chemicals have adverse effects. They destroy the ecological environment and even have toxic effects on human beings. In this context, the development of botanical pesticides is relevant. One potential botanical pesticide is chelerythrine...

journal_title：Pharmacognosy magazine

authors： Wei Q,Zhao M,Li X

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Zingiber officinale Rosc. is not only an important medical plant in China, but also one of the most commonly used plant spices around the world. Early researches in Z. officinale Rosc. were focused on rapid propagation, germplasm preservation, and somatic embryogenesis, only a few reports focused on the gene...

journal_title：Pharmacognosy magazine

authors： Kun-Hua W,Jian-Hua M,He-Ping H,Shan-Lin G

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Vatica diospyroides type LS is a known source of valuable compounds for cancer treatment, however, in contrast little is known about therapeutic efficacy of type SS. OBJECTIVE:This study focused on in vitro cytotoxicity of these fruit extracts, and the cell death mode they induce in breast cancer cells. MA...

journal_title：Pharmacognosy magazine

authors： Srisawat T,Sukpondma Y,Graidist P,Chimplee S,Kanokwiroon K

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Three cultivars seeds of Resina ferulae were analyzed for essential oil composition, Ferula sinkiangensis K. M. Shen, Ferula fukangensis K. M. Shen, and Ferula ovina, investigated differences among different genera of medicinal R. ferulae. MATERIALS AND METHODS:The essential oils were extracted by the method...

journal_title：Pharmacognosy magazine

authors： Li X,Wang Y,Zhu J,Xiao Q

更新日期：2011-04-01 00:00:00

abstract：:Chalcones have been shown to exhibit anti-cancer properties by targeting multiple molecular pathways. It was, therefore, of interest to investigate flavokawain C (FKC), a naturally occurring chalcone, which can be isolated from Kava (Piper methysticum Forst) root extract. The aim of this study was to investigate the i...

journal_title：Pharmacognosy magazine

authors： Phang CW,Karsani SA,Abd Malek SN

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Haberlea rhodopensis Friv. (Gesneriaceae) is a rare poikilohydric endemic and preglacial relict growing in Balkan Peninsula. Previous investigations demonstrated strong antioxidant, antimicrobial and antimutagenic potential of alcoholic extract from the plant. OBJECTIVE:The isolation of known caffeoyl pheny...

journal_title：Pharmacognosy magazine

authors： Kondeva-Burdina M,Zheleva-Dimitrova D,Nedialkov P,Girreser U,Mitcheva M

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Mimosa caesalpiniifolia Benth. (Leguminosae) is widely found in the Brazilian Northeast region and markedly contributes to production of pollen and honey, being considered an important honey plant in this region. OBJECTIVE:To investigate the chemical composition of the ethanol extract of leaves from M. caes...

journal_title：Pharmacognosy magazine

authors： Monção NB,Costa LM,Arcanjo DD,Araújo BQ,Lustosa Mdo C,Rodrigues KA,Carvalho FA,Costa AP,Lopes Citó AM

更新日期：2014-08-01 00:00:00

abstract：Background:Hypertension is a great global health challenge and it mostly requires drug combination therapy with the various advantages. Metoprolol (MP) and paeoniflorin are both commonly used for the treatment of hypertension. However, whether they exert synergistic effects on antihypertension or not remains unclear, e...

journal_title：Pharmacognosy magazine

authors： Li B,Yang ZB,Lei SS,Su J,Jin ZW,Chen SH,Lv GY

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The technique of microscopy has been applied for identification of Chinese materia medica (CMM) since decades. However, very few scientific publications report the combination of conventional microscopy and high performance liquid chromatography (HPLC) techniques for further application to quality assessment...

journal_title：Pharmacognosy magazine

authors： Liang L,Zhao Z,Kang T

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Traditionally, a number of medicinal plants are used to treat various types of hepatic disorders but few of them were pharmacologically evaluated for their safety and efficacy. The combination of Andrographis paniculata (Kalmegha), Tinospora cordifolia (Guduchi), and Solanum nigrum (Kakmachi) was traditional...

journal_title：Pharmacognosy magazine

authors： Singh DP,Awasthi H,Luqman S,Singh S,Mani D

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Gegenqinlian decoction (GQD) is a famous traditional medicine recipe. It is composed of four herbs including Radix Puerariae (GG), Radix Scutellariae (HQ), Rhizoma Coptidis (HL) and Radix Glycyrrhizae (GC), which is widely used for treating gastro-intestinal disorders in the clinical practice of Traditional ...

journal_title：Pharmacognosy magazine

authors： Zhang Y,Yuan J,Wang Y,Wang Y,An R,Wang X

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To determine the free amino acid contents of chamomile flowers using reverse-phase high-performance column chromatography preceded by pre-column derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC), and to determine the reliability of this method. MATERIALS AND METHODS:Derivatization wit...

journal_title：Pharmacognosy magazine

authors： Ma X,Zhao D,Li X,Meng L

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The RP-HPLC resolution of two triterpenic acid isomers was unstable. OBJECTIVE:To separate the oleanolic acid (OA) and ursolic acid (UA) simply within RP-HPLC. MATERIALS AND METHODS:The separation ability of five stationary phases was studied with the retention effect of their carbon loads. Also the resolu...

journal_title：Pharmacognosy magazine

authors： Zhang Y,Xue K,Zhao EY,Li Y,Yao L,Yang X,Xie X

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Plant sterols are the major source of micronutrients and have not shown any obvious side effects in human. β-sitosterol is one of the most prevalent phytosterols which have been recorded in ancient medicinal history for its use in the treatment of many chronic diseases, especially cancer. The modulations of ...

journal_title：Pharmacognosy magazine

authors： Sharmila R,Sindhu G

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Tephrosia purpurea is an Indian herb used in traditional medicine to treat various diseases such as jaundice, asthma, liver and urinary disorders. However, the anti-cancer potential of T. purpurea on hepatocellular carcinoma (HCC) is poorly understood. Therefore, this study aims to investigate the anti-cance...

journal_title：Pharmacognosy magazine

authors： Padmapriya R,Gayathri L,Ronsard L,Akbarsha MA,Raveendran R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is one of the leading chronic diseases worldwide. In patients with poor glycemic control, high blood glucose level may lead to other life-threatening complications. Pandanus amaryllifolius Roxb. (PA) leaves are used in traditional medicine for the treatment of diabetes. OBJECTIVE:This stud...

journal_title：Pharmacognosy magazine

authors： Chiabchalard A,Nooron N

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Isolation and structure elucidation of flavan-3-ol constituents from the leaves of Ficus spragueana and their cytotoxic activity. MATERIALS AND METHODS:Different open silica gel column chromatographic techniques with different solvent systems were used for the separation of the constituents of the ethyl ace...

journal_title：Pharmacognosy magazine

authors： Ragab EA,Mohammed Ael-S,Abbass HS,Kotb SI

更新日期：2013-04-01 00:00:00

abstract：CONTEXT:It was found that the essential oil of Acorus calamus rhizomes showed insecticidal activity. AIM:The aim of this study was to determine the chemical composition of the essential oil from A. calamus rhizomes, evaluate insecticidal and repellant activity against Lasioderma serricorne (LS) and Tribolium castaneum...

journal_title：Pharmacognosy magazine

authors： Chen HP,Yang K,Zheng LS,You CX,Cai Q,Wang CF

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The majority of Achillea species are the most important native economic plants of Anatolia. They include highly bioactive compounds, so they have therapeutic applications. OBJECTIVE:In the present study, the aim was to investigate in vitro anti-oxidant, cytotoxic and pro-apoptotic effects of Achillea tereti...

journal_title：Pharmacognosy magazine

authors： Bali EB,Açık L,Elçi P,Sarper M,Avcu F,Vural M

更新日期：2015-10-01 00:00:00

abstract：:Alcohol addiction is a worldwide problem. It has mainly two components: dependence and withdrawal. Characteristic properties of most anti-addictive compounds include anti-anxiety, anticonvulsant, antidepressant, and nootropic actions. Shankhpushpi (Convolvulus pluricaulis. Convolvulaceae), known ethnopharmacologically...

journal_title：Pharmacognosy magazine

authors： Heba M,Faraz S,Banerjee S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The present study reports and compares the results of Gas Chromatographic-Mass analyses of Pulicaria jaubertii leaf (P-1) and root (P-2) essential oils, as well as their in vitro antimicrobial and cytotoxic activities. MATERIALS AND METHODS:The chemical composition of P-1 and P-2 essential oils of P. jauber...

journal_title：Pharmacognosy magazine

authors： Fawzy GA,Al Ati HY,El Gamal AA

更新日期：2013-01-01 00:00:00

abstract：Introduction:In the present work, the method to extract, isolate, and characterize orange peel pectin using soxhlation, and thereafter, the use of this polymer-polymer in the formulation of fast dispersable and slow-releasing tablet has been studied. Thereafter, the evaluation and comparison of fast dispersible/slow-re...

journal_title：Pharmacognosy magazine

authors： Srivastava P,Singh M,Bhargava S

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Recently, many efforts have been made to discover new products of natural origin which can limit the xenobiotic-induced hepatic injury. Carbon tetrachloride (CCl4) is a highly toxic chemical that is widely used to study hepatotoxicity in animal models. OBJECTIVE:The present study was conducted to investigat...

journal_title：Pharmacognosy magazine

authors： Abdou RH,Saleh SY,Khalil WF

更新日期：2015-05-01 00:00:00