Bioassay-guided isolation, identification and molecular ligand-target insight of lipoxygenase inhibitors from leaves of Anisomeles malabarica R.Br.

abstract：BACKGROUND:Zingiber officinale Rosc. is not only an important medical plant in China, but also one of the most commonly used plant spices around the world. Early researches in Z. officinale Rosc. were focused on rapid propagation, germplasm preservation, and somatic embryogenesis, only a few reports focused on the gene...

journal_title：Pharmacognosy magazine

authors： Kun-Hua W,Jian-Hua M,He-Ping H,Shan-Lin G

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Annona vepretorum (AV) is a native tree from Caatinga biome (semiarid region of Brazil) popularly known as "araticum" and "pinha da Caatinga." OBJECTIVE:This study was carried out to evaluate the chemical constituents and antioxidant activity (AA) of the essential oil from the leaves from AV (EO-Av) collect...

journal_title：Pharmacognosy magazine

authors： Araújo Cde S,de Oliveira AP,Lima RN,Alves PB,Diniz TC,da Silva Almeida JR

更新日期：2015-07-01 00:00:00

abstract：Background:Meyna spinosa (M.S) (Roxb.) ex Link and Oroxylum indicum (O.I) (Linn.) Vent, widely used traditional Northeast Indian medicinal plant used for various purposes, have not yet explored for safety profile. Objective:To investigate the safety profile of M.S (Roxb.) ex Link leaves and O.I (Linn.) Vent stem bark ...

journal_title：Pharmacognosy magazine

authors： Singh S,Chattopadhyay P,Borthakur SK,Policegoudra R

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The active ingredients and thus pharmacological efficacy of traditional Chinese medicine (TCM) at different degrees of parching process vary greatly. OBJECTIVE:Near-infrared spectroscopy (NIR) was used to develop a new method for rapid online analysis of TCM parching process, using two kinds of chemical ind...

journal_title：Pharmacognosy magazine

authors： Li K,Wang W,Liu Y,Jiang S,Huang G,Ye L

更新日期：2017-04-01 00:00:00

abstract：AIMS:The study is conducted to evaluate the immunomodulatory, cytotoxicity, and antioxidant potential of Ziziphus mauritiana (Rhamnaceae). Phytochemical analysis of Z. mauritiana revealed the presence of alkaloids, anthraquinone glycoside, cardiac glycoside, saponin, tannin, and flavonoids. METHODOLOGY:The cytotoxicit...

journal_title：Pharmacognosy magazine

authors： Afzal S,Batool M,Ch BA,Ahmad A,Uzair M,Afzal K

更新日期：2017-07-01 00:00:00

abstract：:The hexane, ethylacetate and methanol extracts from Bauhinia tomentosa and Bauhinia vahlii roots were tested for their antimicrobial activity against Gram-positive bacteria (four strains), Gram-negative bacteria (three strains) and three fungi strains using microdilution methods, for the determination of minimal inhib...

journal_title：Pharmacognosy magazine

authors： Dugasani S,Balijepalli MK,Tandra S,Pichika MR

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Recently, many efforts have been made to discover new products of natural origin which can limit the xenobiotic-induced hepatic injury. Carbon tetrachloride (CCl4) is a highly toxic chemical that is widely used to study hepatotoxicity in animal models. OBJECTIVE:The present study was conducted to investigat...

journal_title：Pharmacognosy magazine

authors： Abdou RH,Saleh SY,Khalil WF

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Essential oil of Ocimum sanctum Linn. exhibited various pharmacological activities including antifungal and antimicrobial activities. In this study, we analyzed the anticancer and apoptosis mechanisms of Ocimum sanctum essential oil (OSEO). OBJECTIVE:To trigger the apoptosis mechanism in human breast cancer...

journal_title：Pharmacognosy magazine

authors： Manaharan T,Thirugnanasampandan R,Jayakumar R,Kanthimathi MS,Ramya G,Ramnath MG

更新日期：2016-05-01 00:00:00

abstract：Background:Leaves of Costus pictus D. Don, (insulin plant) are used as dietary supplement for the treatment of diabetes. Objective:The antidiabetic activity of this plant is well documented, but its activity on different cell types and mechanism remains unknown. Thus, the present study evaluates the cytotoxicity of C....

journal_title：Pharmacognosy magazine

authors： Neethu PV,Suthindhiran K,Jayasri MA

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Suillus granulatus is an edible and medicinal fungus in China. S. granulatus polysaccharide (SGP) was considered as the main bioactivity compounds in S. granulatus. Therefore, the extraction of SGP and their antioxidant activities were studied in this work. MATERIALS AND METHODS:Fruiting bodies of S. granul...

journal_title：Pharmacognosy magazine

authors： Zhou F,Yan S,Chen S,Gong L,Su T,Wang Z

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Cyperus scariosus R. Br and Cyperus rotundus L are widely used in ayurvedic preparation for the treatment of diabetes and other diseases. The early literature, so far, does not indicate the presence of any bioactive principle isolated from these plants. OBJECTIVE:To identify free radical scavenging, anti-di...

journal_title：Pharmacognosy magazine

authors： Kakarla L,Katragadda SB,Tiwari AK,Kotamraju KS,Madhusudana K,Kumar DA,Botlagunta M

更新日期：2016-07-01 00:00:00

abstract：CONTEXT:Scyphiphora hydrophyllacea is a shrub mangrove plant of the family Rubiaceae and not yet been studied for anti-hepatocarcinogenic effects. OBJECTIVES:We investigated possible in vitro anti-hepatocarcinogenic and antioxidant properties of S. hydrophyllacea. MATERIALS AND METHODS:Dried leaves of S. hydrophyllac...

journal_title：Pharmacognosy magazine

authors： Samarakoon SR,Shanmuganathan C,Ediriweera MK,Piyathilaka P,Tennekoon KH,Thabrew I,Galhena P,De Silva ED

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The 7-hydroxycalamenenene-rich essential oil (EO) obtained from the leaves of Croton cajucara (red morphotype) have been described as active against bacteria, protozoa, and fungi species. In this work, we aimed to evaluate the effectiveness of 7-hydroxycalamenenene against Candida albicans and nonalbicans sp...

journal_title：Pharmacognosy magazine

authors： Azevedo MM,Almeida CA,Chaves FC,Rodrigues IA,Bizzo HR,Alviano CS,Alviano DS

更新日期：2016-01-01 00:00:00

abstract：Background:Chemical fungicides are widely used to control crop diseases, but these chemicals have adverse effects. They destroy the ecological environment and even have toxic effects on human beings. In this context, the development of botanical pesticides is relevant. One potential botanical pesticide is chelerythrine...

journal_title：Pharmacognosy magazine

authors： Wei Q,Zhao M,Li X

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Mimosa caesalpiniifolia Benth. (Leguminosae) is widely found in the Brazilian Northeast region and markedly contributes to production of pollen and honey, being considered an important honey plant in this region. OBJECTIVE:To investigate the chemical composition of the ethanol extract of leaves from M. caes...

journal_title：Pharmacognosy magazine

authors： Monção NB,Costa LM,Arcanjo DD,Araújo BQ,Lustosa Mdo C,Rodrigues KA,Carvalho FA,Costa AP,Lopes Citó AM

更新日期：2014-08-01 00:00:00

abstract：:Alcohol addiction is a worldwide problem. It has mainly two components: dependence and withdrawal. Characteristic properties of most anti-addictive compounds include anti-anxiety, anticonvulsant, antidepressant, and nootropic actions. Shankhpushpi (Convolvulus pluricaulis. Convolvulaceae), known ethnopharmacologically...

journal_title：Pharmacognosy magazine

authors： Heba M,Faraz S,Banerjee S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Radix Saposhnikoviae (RS) exerts anti-inflammatory, analgesic, antipyretic, antioxidation effects and has been used in traditional Chinese medicine to treat common colds, headache, and rheumatoid arthritis. Prim-O-glucosylcimifugin (POG) is the highest content chromone and one of the major active constituent...

journal_title：Pharmacognosy magazine

authors： Zhou J,Sun YY,Sun MY,Mao WA,Wang L,Zhang J,Zhang H

更新日期：2017-07-01 00:00:00

abstract：Background:Enterococcus faecalis (Ef) is a multidrug-resistant pathogenic bacteria associated with hospital-acquired infections. Ef is involved in a number of infectious diseases. It generally infects patients with the weekend immune system, i.e. a person mostly acquires Ef infections in the hospital, especially in int...

journal_title：Pharmacognosy magazine

authors： Katva S,Das S,Moti HS,Jyoti A,Kaushik S

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Fissistigma polyanthum is a liane belonging to the Annonaceae family and it is one of the most important crude drugs in traditional Chinese medicine. OBJECTIVE:The objective was to describe the structural elucidation and the free-radical-scavenging activities of the isolated compounds from Fissistigma polya...

journal_title：Pharmacognosy magazine

authors： Fan H,Zheng T,Chen Y,Yang GZ

更新日期：2012-04-01 00:00:00

abstract：CONTEXT:Recent studies have demonstrated that baicalin has antihyperglycemic effects by inhibiting lipid peroxidation. Baicalin is low hydrophilic and poorly absorbed after oral administration. Thus, a suitable formulation is highly desired to overcome the disadvantages of baicalin. OBJECTIVE:The objective of this wor...

journal_title：Pharmacognosy magazine

authors： Shi F,Wei Z,Zhao Y,Xu X

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Rattan tea is a medicinal plant that has been used for many years for the treatment of inflammation, fatty liver, tumor, diabetes, and hyperlipidemia. OBJECTIVE:A green and novel approach based on surfactant-mediated, ultrasonic-assisted extraction (SM-UAE) was developed for the extraction of antioxidant po...

journal_title：Pharmacognosy magazine

authors： Li F,Raza A,Wang YW,Xu XQ,Chen GH

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Haberlea rhodopensis Friv. (Gesneriaceae) is a rare poikilohydric endemic and preglacial relict growing in Balkan Peninsula. Previous investigations demonstrated strong antioxidant, antimicrobial and antimutagenic potential of alcoholic extract from the plant. OBJECTIVE:The isolation of known caffeoyl pheny...

journal_title：Pharmacognosy magazine

authors： Kondeva-Burdina M,Zheleva-Dimitrova D,Nedialkov P,Girreser U,Mitcheva M

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Buddleja davidii and B. albiflora are two different original plants of the famous crude medicine "Diaoyangchen". MATERIALS AND METHODS:An ultraviolet-visible spectrophotometric method and a HPLC method were used for the determination of total and individual flavonoids (luteolin and apigenin) contents from t...

journal_title：Pharmacognosy magazine

authors： Ying C,Wan D

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Three cultivars seeds of Resina ferulae were analyzed for essential oil composition, Ferula sinkiangensis K. M. Shen, Ferula fukangensis K. M. Shen, and Ferula ovina, investigated differences among different genera of medicinal R. ferulae. MATERIALS AND METHODS:The essential oils were extracted by the method...

journal_title：Pharmacognosy magazine

authors： Li X,Wang Y,Zhu J,Xiao Q

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To determine the free amino acid contents of chamomile flowers using reverse-phase high-performance column chromatography preceded by pre-column derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC), and to determine the reliability of this method. MATERIALS AND METHODS:Derivatization wit...

journal_title：Pharmacognosy magazine

authors： Ma X,Zhao D,Li X,Meng L

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is one of the leading chronic diseases worldwide. In patients with poor glycemic control, high blood glucose level may lead to other life-threatening complications. Pandanus amaryllifolius Roxb. (PA) leaves are used in traditional medicine for the treatment of diabetes. OBJECTIVE:This stud...

journal_title：Pharmacognosy magazine

authors： Chiabchalard A,Nooron N

更新日期：2015-01-01 00:00:00

abstract：Background:At present, approximately 17-25 million people in the world suffer from Alzheimer's disease (AD). The most efficacious and acceptable therapeutic drug clinically are the acetylcholinesterase inhibitors (AChEIs). Yinhuang oral liquid is a Chinese medicine preparation which contains AChEIs according to the lit...

journal_title：Pharmacognosy magazine

authors： Zhang H,Guo Y,Meng L,Sun H,Yang Y,Gao Y,Sun J

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Traditionally, a number of medicinal plants are used to treat various types of hepatic disorders but few of them were pharmacologically evaluated for their safety and efficacy. The combination of Andrographis paniculata (Kalmegha), Tinospora cordifolia (Guduchi), and Solanum nigrum (Kakmachi) was traditional...

journal_title：Pharmacognosy magazine

authors： Singh DP,Awasthi H,Luqman S,Singh S,Mani D

更新日期：2015-10-01 00:00:00

abstract：CONTEXT:Two of the important algae from Persian Gulf are Gracilaria salicornia and Hypnea flageliformis (Rhodophyta). Antibacterial, antifungal, and cytotoxic effects of the mentioned algae have been presented in the previous studies. AIM:In this study, the isolation and structural elucidation of the sterols from thes...

journal_title：Pharmacognosy magazine

authors： Nasir M,Saeidnia S,Mashinchian-Moradi A,Gohari AR

更新日期：2011-04-01 00:00:00

abstract：:Alpinia purpurata or red ginger was studied for its phytochemical constituents as part of our growing interest on Philippine Zingiberaceae plants that may exhibit antimycobacterial activity. The hexane and dichloromethane subextracts of the leaves were fractionated and purified using silica gel chromatography to affor...

journal_title：Pharmacognosy magazine

authors： Villaflores OB,Macabeo AP,Gehle D,Krohn K,Franzblau SG,Aguinaldo AM

更新日期：2010-10-01 00:00:00