Phytochemicals and Cytotoxicity of Launaea procumbens on Human Cancer Cell Lines.

abstract：BACKGROUND:Diabetes mellitus is one of the leading chronic diseases worldwide. In patients with poor glycemic control, high blood glucose level may lead to other life-threatening complications. Pandanus amaryllifolius Roxb. (PA) leaves are used in traditional medicine for the treatment of diabetes. OBJECTIVE:This stud...

journal_title：Pharmacognosy magazine

authors： Chiabchalard A,Nooron N

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Vatica diospyroides type LS is a known source of valuable compounds for cancer treatment, however, in contrast little is known about therapeutic efficacy of type SS. OBJECTIVE:This study focused on in vitro cytotoxicity of these fruit extracts, and the cell death mode they induce in breast cancer cells. MA...

journal_title：Pharmacognosy magazine

authors： Srisawat T,Sukpondma Y,Graidist P,Chimplee S,Kanokwiroon K

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Sesquiterpenoids, such as tussilagone, has effects of raising blood pressure, antiplatelet aggregation, and anti-inflammation activities, which is regarded as index compound for quality control of Tussilago farfara L. OBJECTIVE:This study was aimed to obtain an effective method for fast isolation of sesquit...

journal_title：Pharmacognosy magazine

authors： Cao K,Xu Y,Zhao TM,Zhang Q

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Sophora flavescens Aiton is an important medicinal plant in China. Early in vitro researches of S. flavescens were focused on callus induction and cell suspension culture, only a few were concerned with in vitro multiplication. OBJECTIVE:To establish and optimize the rapid propagation technology of S. flavesce...

journal_title：Pharmacognosy magazine

authors： Kun-Hua W,Shan-Lin G,He-Ping H

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Aronia melanocarpa (Michx.) Elliot fruits are very rich in polyphenols - procyanidins, flavonoids, and phenolic acids. OBJECTIVE:On rat hepatocytes, isolated by two-stepped collagenase perfusion, we investigated the effect of A. melanocarpa fruit juice (AMFJ) in two models of liver toxicity caused by (i) me...

journal_title：Pharmacognosy magazine

authors： Kondeva-Burdina M,Valcheva-Kuzmanova S,Markova T,Mitcheva M,Belcheva A

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:Three cultivars seeds of Resina ferulae were analyzed for essential oil composition, Ferula sinkiangensis K. M. Shen, Ferula fukangensis K. M. Shen, and Ferula ovina, investigated differences among different genera of medicinal R. ferulae. MATERIALS AND METHODS:The essential oils were extracted by the method...

journal_title：Pharmacognosy magazine

authors： Li X,Wang Y,Zhu J,Xiao Q

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To optimization of extraction of antioxidant compounds from guava (Psidium guajava L.) leaves and showed that the guava leaves are the potential source of antioxidant compounds. MATERIALS AND METHODS:The bioactive polysaccharide compounds of guava leaves (P. guajava L.) were obtained using ultrasonic-assiste...

journal_title：Pharmacognosy magazine

authors： Kong F,Yu S,Feng Z,Wu X

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Radix Saposhnikoviae (RS) exerts anti-inflammatory, analgesic, antipyretic, antioxidation effects and has been used in traditional Chinese medicine to treat common colds, headache, and rheumatoid arthritis. Prim-O-glucosylcimifugin (POG) is the highest content chromone and one of the major active constituent...

journal_title：Pharmacognosy magazine

authors： Zhou J,Sun YY,Sun MY,Mao WA,Wang L,Zhang J,Zhang H

更新日期：2017-07-01 00:00:00

abstract：:Chalcones have been shown to exhibit anti-cancer properties by targeting multiple molecular pathways. It was, therefore, of interest to investigate flavokawain C (FKC), a naturally occurring chalcone, which can be isolated from Kava (Piper methysticum Forst) root extract. The aim of this study was to investigate the i...

journal_title：Pharmacognosy magazine

authors： Phang CW,Karsani SA,Abd Malek SN

更新日期：2017-07-01 00:00:00

abstract：:Alcohol addiction is a worldwide problem. It has mainly two components: dependence and withdrawal. Characteristic properties of most anti-addictive compounds include anti-anxiety, anticonvulsant, antidepressant, and nootropic actions. Shankhpushpi (Convolvulus pluricaulis. Convolvulaceae), known ethnopharmacologically...

journal_title：Pharmacognosy magazine

authors： Heba M,Faraz S,Banerjee S

更新日期：2017-01-01 00:00:00

abstract：CONTEXT:Scyphiphora hydrophyllacea is a shrub mangrove plant of the family Rubiaceae and not yet been studied for anti-hepatocarcinogenic effects. OBJECTIVES:We investigated possible in vitro anti-hepatocarcinogenic and antioxidant properties of S. hydrophyllacea. MATERIALS AND METHODS:Dried leaves of S. hydrophyllac...

journal_title：Pharmacognosy magazine

authors： Samarakoon SR,Shanmuganathan C,Ediriweera MK,Piyathilaka P,Tennekoon KH,Thabrew I,Galhena P,De Silva ED

更新日期：2017-01-01 00:00:00

abstract：Background:Leaves of Costus pictus D. Don, (insulin plant) are used as dietary supplement for the treatment of diabetes. Objective:The antidiabetic activity of this plant is well documented, but its activity on different cell types and mechanism remains unknown. Thus, the present study evaluates the cytotoxicity of C....

journal_title：Pharmacognosy magazine

authors： Neethu PV,Suthindhiran K,Jayasri MA

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Methyl protodioscin (MPD) is a furostanol bisglycoside with antitumor properties. It has been shown to reduce proliferation, cause cell cycle arrest. OBJECTIVE:The present study elucidates the mechanism underlying MPD's apoptotic effects, using the A549 human lung cancer cell line. MATERIALS AND METHODS:Th...

journal_title：Pharmacognosy magazine

authors： Bai Y,Qu XY,Yin JQ,Wu L,Jiang H,Long HW,Jia Q

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Pogostemonis Herba, the dried aerial part of Pogostemon cablin Blanco, is a well-known materia medica in Asia that is widely used for syndrome of gastrointestinal dysfunctions. OBJECTIVE:This study was undertaken to examine whether Pogostemon cablin extract (PCe) might have any beneficial effect on hypoxia ...

journal_title：Pharmacognosy magazine

authors： Lim CY,Kim BY,Lim SH,Cho SI

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:The aim was to study and identify free radicals scavenging and antihyperglycemic principles in fruit of Piper attenuatum. MATERIALS AND METHODS:Bioassay guided identification of extracts possessing potent free radical scavenging activity, and isolation of compounds was done. Chloroform extract of P. attenuat...

journal_title：Pharmacognosy magazine

authors： Reddy SD,Siva B,Poornima B,Kumar DA,Tiwari AK,Ramesh U,Babu KS

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The purple sweet potato, Ipomoea batatas, belongs to the family Convolvulaceae. It is one of the most widely consumed tubers in Asia and is found in many dishes. Many people with diabetes eat purple sweet potato tubers to help reduce blood glucose in China. OBJECTIVE:To predict the ultrasonic conditions for...

journal_title：Pharmacognosy magazine

authors： Guo H,Kong F,Yan C

更新日期：2017-07-01 00:00:00

abstract：:The hexane, ethylacetate and methanol extracts from Bauhinia tomentosa and Bauhinia vahlii roots were tested for their antimicrobial activity against Gram-positive bacteria (four strains), Gram-negative bacteria (three strains) and three fungi strains using microdilution methods, for the determination of minimal inhib...

journal_title：Pharmacognosy magazine

authors： Dugasani S,Balijepalli MK,Tandra S,Pichika MR

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Fissistigma polyanthum is a liane belonging to the Annonaceae family and it is one of the most important crude drugs in traditional Chinese medicine. OBJECTIVE:The objective was to describe the structural elucidation and the free-radical-scavenging activities of the isolated compounds from Fissistigma polya...

journal_title：Pharmacognosy magazine

authors： Fan H,Zheng T,Chen Y,Yang GZ

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Manilkara subsericea (Sapotaceae) is a species widely spread in the sandbanks of Restinga de Jurubatiba National Park (Rio de Janeiro, Brazil). It is commonly known as "maçaranduba", "maçarandubinha" and "guracica", being used in this locality as food, and timber. However, M. subsericea remains almost unexpl...

journal_title：Pharmacognosy magazine

authors： de Almeida FB,Fernandes CP,Romao W,Vanini G,Costa HB,França HS,Santos MG,Carvalho JC,Falcão DQ,Rocha L

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Occurrence of integristerone A (1), 20-hydroxyecdysone (2), ecdysone (3), 2-deoxy-20-hydroxyecdysone (4) has been analyzed in 64 species of the East Asian Caryophyllaceae. MATERIALS AND METHODS:Ecdysteroid content was determinate by high-performance liquid chromatography (HPLC). HPLC with a high-resolution ...

journal_title：Pharmacognosy magazine

authors： Novozhilova E,Rybin V,Gorovoy P,Gavrilenko I,Doudkin R

更新日期：2015-05-01 00:00:00

abstract：CONTEXT:Two of the important algae from Persian Gulf are Gracilaria salicornia and Hypnea flageliformis (Rhodophyta). Antibacterial, antifungal, and cytotoxic effects of the mentioned algae have been presented in the previous studies. AIM:In this study, the isolation and structural elucidation of the sterols from thes...

journal_title：Pharmacognosy magazine

authors： Nasir M,Saeidnia S,Mashinchian-Moradi A,Gohari AR

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Buddleja davidii and B. albiflora are two different original plants of the famous crude medicine "Diaoyangchen". MATERIALS AND METHODS:An ultraviolet-visible spectrophotometric method and a HPLC method were used for the determination of total and individual flavonoids (luteolin and apigenin) contents from t...

journal_title：Pharmacognosy magazine

authors： Ying C,Wan D

更新日期：2012-10-01 00:00:00

abstract：Background:Hypertension is a great global health challenge and it mostly requires drug combination therapy with the various advantages. Metoprolol (MP) and paeoniflorin are both commonly used for the treatment of hypertension. However, whether they exert synergistic effects on antihypertension or not remains unclear, e...

journal_title：Pharmacognosy magazine

authors： Li B,Yang ZB,Lei SS,Su J,Jin ZW,Chen SH,Lv GY

更新日期：2018-01-01 00:00:00

abstract：Background:Chemical fungicides are widely used to control crop diseases, but these chemicals have adverse effects. They destroy the ecological environment and even have toxic effects on human beings. In this context, the development of botanical pesticides is relevant. One potential botanical pesticide is chelerythrine...

journal_title：Pharmacognosy magazine

authors： Wei Q,Zhao M,Li X

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Polygonum multiflorum is an important medicinal plant. Hairy roots systems obtained by transforming plant tissues with the natural genetic engineer Agrobacterium rhizogenes can produce valuable biological active substances, which have immense potential in the pharmaceutical industry. OBJECTIVE:To optimize t...

journal_title：Pharmacognosy magazine

authors： Huang B,Lin H,Yan C,Qiu H,Qiu L,Yu R

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:A Korean herbal medicine, KOTMIN13, composed of Inula japonica Thunberg, Trichosanthes kirilowii Maximowicz var. japonica kitamura, Peucedanum praeruptorum Dunn, and Allium macrostemon Bge, has been used for anti-allergic and anti-asthmatic treatment in oriental clinics, but its activity has not been investi...

journal_title：Pharmacognosy magazine

authors： Lee E,Kim SG,Park NY,Park HH,Jeong KT,Choi J,Lee IH,Lee H,Lee E

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:To determine the free amino acid contents of chamomile flowers using reverse-phase high-performance column chromatography preceded by pre-column derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC), and to determine the reliability of this method. MATERIALS AND METHODS:Derivatization wit...

journal_title：Pharmacognosy magazine

authors： Ma X,Zhao D,Li X,Meng L

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The active ingredients and thus pharmacological efficacy of traditional Chinese medicine (TCM) at different degrees of parching process vary greatly. OBJECTIVE:Near-infrared spectroscopy (NIR) was used to develop a new method for rapid online analysis of TCM parching process, using two kinds of chemical ind...

journal_title：Pharmacognosy magazine

authors： Li K,Wang W,Liu Y,Jiang S,Huang G,Ye L

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Lavatera cretica L. was used in folk medicine as anti-inflammatory among other applications. As inflammation is many times associated with oxidative processes, the aim of the present work was to evaluate the ability of aqueous extracts obtained from different parts of L. cretica to prevent oxidation or infla...

journal_title：Pharmacognosy magazine

authors： Ben-Nasr S,Aazza S,Mnif W,Miguel Mda G

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Silymarin, an active polyphenolic fraction of Silybum marianum, and high flavonoid content of Fagopyrum possess various interesting biological activities. The substituted pyrazine-2-carboxamides were previously used as effective elicitors of studied secondary metabolites. OBJECTIVE:To study the effect of ne...

journal_title：Pharmacognosy magazine

authors： Tůmová L,Tůma J,Doležal M,Dučaiová Z,Kubeš J

更新日期：2016-01-01 00:00:00