Phenotypic and functional comparison of optimum culture conditions for upscaling of dental pulp stem cells.

abstract：:Genetic analysis has strongly implicated human FHIT (Fragile Histidine Triad) as a tumor suppressor gene, being mutated in a large proportion of early-stage cancers. The functions of the FHIT protein have, however, remained elusive. Here, we investigated aph1+ , the fission yeast homolog of FHIT, for functions related...

journal_title：Cell biology international

authors： Sjölander JJ,Sunnerhagen P

更新日期：2020-02-01 00:00:00

abstract：:The Kv2.1 potassium channel is a principal component of the delayed rectifier I(K) current in the pyramidal neurons of cortex and hippocampus. We used whole-cell patch-clamp recording techniques to systemically compare the electrophysiological properties between the native neuronal I(K) current of cultured rat hippoca...

journal_title：Cell biology international

authors： Liu M,Gong B,Qi Z

更新日期：2008-12-01 00:00:00

abstract：:Human tissues are sophisticated ensembles of various distinct cell types encapsulated in the biomechanical cues of the extracellular matrix. It has been known matrix stiffness plays a pivot role in cellular events and tissue-scale biological processes. Thus, materials that can mimic mechanical environments of tissues ...

journal_title：Cell biology international

authors： Zhao H,Xu K,Zhu P,Wang C,Chi Q

更新日期：2019-02-01 00:00:00

abstract：:Epidermis, a continuously renewing tissue, is maintained by stem cells that proliferate and replenish worn out or damaged cells in the tissue during life. Cultured epidermal stem cells have great potential in scientific research and clinical application. However, isolating a pure and viable population of epidermal ste...

journal_title：Cell biology international

authors： Zhou JX,Jia LW,Yang YJ,Peng S,Cao YJ,Duan EK

更新日期：2004-01-01 00:00:00

abstract：:The effects of NO in its environment may vary considerably depending on various factors. This study shows oxidative mechanism of cellular membrane alterations, which is not associated with triggering of ONOOH generation but is induced by pure NO. Our investigation examined the influence of low concentration of NO (0.1...

journal_title：Cell biology international

authors： Brzeszczynska J,Gwozdzinski K

更新日期：2008-01-01 00:00:00

abstract：:Peritoneal dialysis (PD) is often used to treat patients with end stage renal disease, and its long-term complications include excessive inflammation and oxidative stress. Allograft inflammatory factor 1 (AIF-1), as a cytoplasmic protein, is originally identified from infiltrating macrophages, and it was associated wi...

journal_title：Cell biology international

authors： Zhou Y,Li X,Yuan X,Hao L

更新日期：2019-05-01 00:00:00

abstract：:The efficacies of chemotherapeutic agents are often limited by side effects and acquired drug resistance. We have investigated whether the differential expression pattern of 14-3-3σ affects cisplatin response in non-small cell lung cancer cell lines. Two pairs of parental/cisplatin resistant cell lines (A549/CRA549 an...

journal_title：Cell biology international

authors： Cetintas VB,Tetik A,Cok G,Kucukaslan AS,Kosova B,Gunduz C,Veral A,Eroglu Z

更新日期：2013-01-01 00:00:00

abstract：:Using clonal cell cultures, a significant increase in chromosomal aberrations (aneuplolidy, dicentrics and chromatid breaks) were observed in MCF-7 cells compared with HeLa. BRCA1 expression was lower in MCF-7 cells than in HeLa cells. Since BRCA1 is known to play a role in the maintenance of chromosomal integrity, th...

journal_title：Cell biology international

authors： Kachhap SK,Vetale SP,Dange P,Ghosh SN

更新日期：2001-01-01 00:00:00

abstract：:Most traditional cytotoxic chemotherapeutic agents have poor aqueous solubility and significant toxicity. Hence, there is a need to develop molecule-targeted drugs. Programmed death-ligand 1 (PD-L1) is associated with the prognosis of several cancer types, and blockade of PD-1/PD-L1 signaling increases the amplitude o...

journal_title：Cell biology international

authors： Liu K,Zhou Z,Gao H,Yang F,Qian Y,Jin H,Guo Y,Liu Y,Li H,Zhang C,Guo J,Wan Y,Chen R

更新日期：2019-06-01 00:00:00

abstract：:The action of theophylline on the uptake of alpha-aminoisobutyric acid (AIB; an indicator of anti-inflammatory potency) stimulated by the glucocorticoid, dexamethasone, in cultured rat fibroblast monolayers was evaluated. Theophylline alone (0.1 m m) did not show significant activity (3314+/-27 cpm) compared with the ...

journal_title：Cell biology international

authors： Xenos K,Kalogeromitros D,Markantonis SL,Katsambas A,Katsarou A

更新日期：1998-01-01 00:00:00

abstract：:Growth hormone (GH), given therapeutically in many human diseases, is able to modulate the maturation and function of many cells of immune system. The present study demonstrates the effect of human recombinant GH on the production of acute phase proteins (APP) as well as on the gene expression of junB proto-oncogene o...

journal_title：Cell biology international

authors： Derfalvi B,Igaz P,Fulop KA,Szalai C,Falus A

更新日期：2000-01-01 00:00:00

abstract：:To establish useful human normal cell lines, TERT (telomerase reverse transcriptase) cDNA was transfected into normal female lung fibroblast, TIG-1. After long-term-sub-cultivation of 74 individual clones selected for resistance to G418, we obtained 55 cultures with normal range of life span [75 PDL (population doubli...

journal_title：Cell biology international

authors： Kamada M,Kumazaki T,Matsuo T,Mitsui Y,Takahashi T

更新日期：2012-06-01 00:00:00

abstract：:Extracellular nucleotides cause neutrophil degranulation by activating the purinergic receptor subtype P2Y. However, the molecular mechanism involved in the signal pathway remains unknown. A hypothetical scheme suggesting that leukotriene(s) and leukotriene receptor(s) activation is required for extracellular nucleoti...

journal_title：Cell biology international

authors： Kannan S

更新日期：2003-01-01 00:00:00

abstract：:In plastic and reconstructive field, it would be much beneficial to fabricate an engineered adipose tissue substitute allowing reliable and complete fat tissue regeneration. Tissue engineering chamber (TEC) holds the promise to optimize an adipogenic configuration that is efficacious as well as reproducible. A frequen...

journal_title：Cell biology international

authors： Zhan W,Lu F

更新日期：2017-04-01 00:00:00

abstract：:Ghrelin-O-acyltransferase (GOAT) is a membrane-bound enzyme that attaches eight-carbon octanoate to a serine residue in ghrelin and thereby acylates inactive ghrelin to produce active ghrelin. In this study, we investigated the function of GOAT in the intestinal mucosal barrier. The intestinal mucosal barrier prevents...

journal_title：Cell biology international

authors： Tian P,Lu X,Jin N,Shi J

更新日期：2020-08-01 00:00:00

abstract：:Induction of HO-1 protein can have both beneficial and detrimental effects for cells, including regulating proliferation and apoptosis of several tumours. We have investigated the regulation of HO-1, p38MAPK and mTOR in the context of proliferation, cell cycle events and apoptosis of oesophageal squamous cell carcinom...

journal_title：Cell biology international

authors： Hu JL,Xiao L,Li ZY,Wang Q,Chang Y,Jin Y

更新日期：2013-06-01 00:00:00

abstract：:An acetylcholine (ACh) agonist, carbachol (Cch), causes hepatocytes to proliferate in the presence of hepatic nonparenchymal cells (HNPCs). To identify the HNPCs and ACh receptor subtypes involved in carbachol-induced hepatocyte proliferation (CIHP), we examined two types of vascular cells as candidates for HNPCs medi...

journal_title：Cell biology international

authors： Yoshimura R,Arai J,Endo Y

更新日期：2009-04-01 00:00:00

abstract：:The effect of hypoxia on the differentiation of chronic myeloid leukaemic K562 cells were studied, as was the role of the NHE1 (Na+/H+ exchanger 1). Hypoxia induced differentiation of K562 cells as seen by modifications in their morphological features, up-regulation of C/EBPα (CCAAT/enhancer-binding protein α), and ma...

journal_title：Cell biology international

authors： Jin W,Li Q,Wang J,Chang G,Lin Y,Li H,Wang L,Gao W,Pang T

更新日期：2012-08-01 00:00:00

abstract：:A subcellular fractionation procedure was developed to isolate the different endosomal compartments present during reticulocyte maturation. After reticulocyte lysis and removal of excess haemoglobin by gel chromatography, membrane vesicles were separated over a discontinuous sucrose gradient (10-40%). Two fractions we...

journal_title：Cell biology international

authors： Dardalhon V,Géminard C,Reggio H,Vidal M,Sainte-Marie J

更新日期：2002-01-01 00:00:00

abstract：:The effect of piperine on the fertilization of eggs with sperm was investigated in female hamsters. They were intragastrically treated with piperine at doses of 50 and 100 mg/kg BW from day 1 through day 4 of the oestrous cycle. During piperine treatment, these females were superovulated and artificially inseminated (...

journal_title：Cell biology international

authors： Piyachaturawat P,Pholpramool C

更新日期：1997-07-01 00:00:00

abstract：:Ro52/SSA is an autoantigen that presents in patients with SS (Sjögren's syndrome) and SLE (systemic lupus erythematosus). It increases cell death and redistributes itself to apoptotic blebs, but its pro-apoptotic function has not been completely identified. Overexpression of Ro52/SSA promoted cell apoptosis induced by...

journal_title：Cell biology international

authors： Zhang J,Fang L,Zhu X,Qiao Y,Yu M,Wang L,Chen Y,Yin W,Hua ZC

更新日期：2012-05-01 00:00:00

abstract：:Pioneering single gene study documents pre-mRNA processing proteins participation in the cell-cycle regulation of multi-cellular animals (Andersen and Tapon, 2008, J Biol Chem 283: 31256-67). Whole-genome RNAi screen in Drosophila tissue-culture cell lines demonstrates that 17 genes involved in RNA-processing are requ...

journal_title：Cell biology international

authors： Dubatolova TD,Volkova EI,Omelyanchuk LV

更新日期：2013-02-01 00:00:00

abstract：:Key to mitochondrial activities is the maintenance of mitochondrial morphology, specifically cristae structures formed by the invagination of the inner membrane that are enriched in proteins of the electron transport chain. In Saccharomyces cerevisiae , these cristae folds are a result of the membrane fusion activitie...

journal_title：Cell biology international

authors： Huddleston ME,Xiao N,Both AP,Gordon DM

更新日期：2019-08-23 00:00:00

abstract：:Adaptation of cardiomyocytes to chronic hypoxia in cyanotic patients remains unclear. Mitochondrial biogenesis is enhanced in myocardium from cyanotic patients, which is possibly an adaptive response. Erythropoietin (EPO) in blood and its receptor (EPOR) on cardiomyocytes are upregulated by chronic hypoxia, suggesting...

journal_title：Cell biology international

authors： Qin C,Zhou S,Xiao Y,Chen L

更新日期：2014-03-01 00:00:00

abstract：:The mitogenic effect of TGF-alpha, acidic-FGF, basic-FGF and lithium on normal human breast epithelial cells was studied in a collagen gel culture system using a serum-free 1:1 mixture of Ham's F12 and DME medium containing insulin, cholera toxin and bovine serum albumin. TGF-alpha elicited a strong mitogenic response...

journal_title：Cell biology international

authors： Sakthivel R,Hamdan M,Yang J,Guzman RC,Nandi S

更新日期：1993-04-01 00:00:00

abstract：:Adipose tissue is a potential site of retinoic acid (RA) action, but its physiological significance remains to be clarified. We have examined the effect of all-trans retinoic acid (ATRA) on growth and differentiation of preadipocytes, and on adipokine gene expression in mature adipocytes using human preadipocyte cell ...

journal_title：Cell biology international

authors： Morikawa K,Hanada H,Hirota K,Nonaka M,Ikeda C

更新日期：2013-01-01 00:00:00

abstract：:Investigation of the relative slowness with which trypsin detaches epithelial cells from their adhesions with a substratum suggests that the adherent surface of the cells is normally rather inaccessible to the enzyme. Trypsinisation of cells through a porous filter allowing access of the enzyme to the underside of the...

journal_title：Cell biology international

authors： Simpson K,McGrath M,Curtis A

更新日期：1993-03-01 00:00:00

abstract：:Many disturbances in electrolyte and hormonal balance in the body induced by functional impairment of renal parenchyma may affect the activity of amine precursor uptake and decarboxylation (APUD) cells, which constitute a very important link in the regulation of homeostasis. The aim of the present study was the morpho...

journal_title：Cell biology international

authors： Kasacka I

更新日期：2004-01-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) plays a key role in formation of pleural effusions and in tumorigenesis and progression of malignant mesothelioma. Mesothelial cells (MC) express the viral receptors Toll-like receptor 3 (TLR3), RIG-I and MDA5. Activation of these receptors by viral RNA exemplified by poly(I:C...

journal_title：Cell biology international

authors： Wörnle M,Sauter M,Kastenmüller K,Ribeiro A,Roeder M,Mussack T,Ladurner R,Sitter T

更新日期：2009-02-01 00:00:00

abstract：:Physical forces play a critical role in cell integrity and development, but little is known how cells convert mechanical signals into biochemical responses. This mini-review examines potential molecular mediators like integrins, focal adhesion proteins, and the cytoskeleton in the context of a complex cell structure. ...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2002-01-01 00:00:00