Abstract:
:The relation between codon usage and gene-expression levels is an intensively investigated and discussed topic in the field of molecular evolution. We statistically analyzed 25 Escherichia coli gene sequences by a new classification of synonymous codons and found that (i) there are two distinct types of linkage between codon usage and gene-expression levels in E. coli, and (ii) one of the two kinds of codon preferences (the codon preference concerned with interaction of GC/AT choice at three codon positions) is observed significantly in weakly expressed genes.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Nakamura T,Suyama A,Wada Adoi
10.1016/0014-5793(91)80923-qsubject
Has Abstractpub_date
1991-09-02 00:00:00pages
123-5issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(91)80923-Qjournal_volume
289pub_type
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