Skin blood flow and its oscillatory components in patients with acute myocardial infarction.

Abstract:

BACKGROUND/AIMS:Laser Doppler flowmetry (LDF) was used to determine the influence of acute myocardial infarction (AMI) and of successful reperfusion treatment on basal skin blood flow and its oscillatory components. METHODS:Skin LDF was performed on all extremities in 58 patients 4-9 days after AMI (Killip class I), and in 71 healthy age- and sex-matched controls. Wavelet analysis was applied to evaluate oscillatory components within the interval 0.005-2 Hz. RESULTS:AMI patients had reduced mean flow (p < 0.01) and oscillatory components (p < 0.04) in all extremities. Reperfused (n = 40), compared to nonreperfused (n = 18), patients had higher mean flow and total spectral amplitude at all recording points. The difference was statistically significant only in legs (group median LDF in the left leg was 9.68 AU for reperfused and 5.71 AU for nonreperfused patients, p < 0.04, and 11.47 and 4.24 AU in the right leg, p < 0.01). Reperfused patients had significantly higher total spectral amplitude in both legs (p < 0.04). CONCLUSIONS:In AMI patients, reduced skin blood flow and its oscillatory components may reflect ongoing neurohumoral activation despite absence of clinically apparent heart failure. The reduction of blood flow and its oscillatory components was larger in nonreperfused AMI patients, although they had a comparable left ventricular function.

journal_name

J Vasc Res

authors

Azman-Juvan K,Bernjak A,Urbancic-Rovan V,Stefanovska A,Stajer D

doi

10.1159/000110208

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

164-72

issue

2

eissn

1018-1172

issn

1423-0135

pii

000110208

journal_volume

45

pub_type

杂志文章
  • A simple method for rapid separation of endothelial and smooth muscle mRNA reveals Na/K+ -ATPase alpha-subunit distribution in rat arteries.

    abstract:BACKGROUND/AIMS:The endothelium has been recognized as a key component in the regulation of blood vessels. We designed a simple procedure to separate endothelial and smooth muscle RNA from rat aorta and mesenteric artery and used this method to establish the distribution of Na(+)/K(+)-ATPase alpha-subunit isoforms (NaK...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000095963

    authors: Krenek P,Hamaide MC,Morel N,Wibo M

    更新日期:2006-01-01 00:00:00

  • Evaluation of Biodegradable Stent Graft Coatings in Pig and Rabbit Models.

    abstract:AIMS:Percutaneous coronary intervention is routinely performed to treat occlusive coronary artery disease. Coronary perforation is a potential complication and can be treated with a stent graft. Current stent grafts are associated with high restenosis rates. We tested the safety and feasibility of biodegradable stent g...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000505454

    authors: Taavitsainen J,Tarvainen S,Kuivanen A,Mangiardi EK,Guelcher M,Martin J,Mathur A,Hytönen JP,Ylä-Herttuala S

    更新日期:2020-01-01 00:00:00

  • Role of HOXA9 and VEZF1 in endothelial biology.

    abstract::Proper development of the vascular system as one of the earliest and most critical steps during vertebrate embryogenesis is ensured by the exact spatial and temporal control of gene expression in cells forming the vessel network. Whereas the regulation of vascular system development is well elucidated on the level of ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章,评审

    doi:10.1159/000353287

    authors: Bruderer M,Alini M,Stoddart MJ

    更新日期:2013-01-01 00:00:00

  • Regulation of arachidonic acid release by calcium influx in human endothelial cells.

    abstract::In response to stimuli, endothelial cells release arachidonic acid, a lipid precursor of various vasoactive substances. We have investigated the relationships between cytosolic Ca2+ movements and arachidonic acid release in human umbilical vein endothelial cells. Histamine, a receptor-dependent agonist, and thapsigarg...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000025647

    authors: Millanvoye-Van Brussel E,David-Dufilho M,Pham TD,Iouzalen L,Aude Devynck M

    更新日期:1999-05-01 00:00:00

  • Stroke-prone SHR vascular muscle Ca2+ current amplitudes correlate with lethal increases in blood pressure.

    abstract::Studies on the possible causal relationship between the Ca2+ channel current density in the vascular muscle cell (VMC) and increases in blood pressure were extended by a comparison of stroke-prone spontaneously hypertensive rats (SP-SHR) with N/nih outbred normotensive rats. Maximal amplitudes of both L-type and T-typ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000159064

    authors: Self DA,Bian K,Mishra SK,Hermsmeyer K

    更新日期:1994-11-01 00:00:00

  • The anti-apoptotic activity of albumin for endothelium is mediated by a partially cryptic protein domain and reduced by inhibitors of G-coupled protein and PI-3 kinase, but is independent of radical scavenging or bound lipid.

    abstract::Increased vascular disease occurs with low albumin (human serum albumin, HSA), possibly reflecting specific inhibition of endothelial apoptosis reported for tissue culture. Despite the reported specificity for endothelial protection by HSA, the high but physiological concentrations needed appear more consistent with n...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000101777

    authors: Bolitho C,Bayl P,Hou JY,Lynch G,Hassel AJ,Wall AJ,Zoellner H

    更新日期:2007-01-01 00:00:00

  • Glucagon-Like Peptide-1 Receptor Activation Does not Affect Re-Endothelialization but Reduces Intimal Hyperplasia via Direct Effects on Smooth Muscle Cells in a Nondiabetic Model of Arterial Injury.

    abstract:UNLABELLED:Diabetic patients have an increased risk of restenosis and late stent thrombosis after angioplasty, i.e. complications that are related to a defective re-endothelialization. Exendin-4, a stable glucagon-like peptide (GLP)-1 receptor agonist, has been suggested to influence the formation of intimal hyperplasi...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000381097

    authors: Eriksson L,Saxelin R,Röhl S,Roy J,Caidahl K,Nyström T,Hedin U,Razuvaev A

    更新日期:2015-01-01 00:00:00

  • Blood outgrowth endothelial cells reduce hypoxia-mediated fibroblast to myofibroblast conversion by decreasing proangiogenic cytokines.

    abstract:PURPOSE:Hypoxic conditions cause fibroblasts to differentiate into alpha smooth-muscle cell actin (α -SMA)-positive cells, i.e. myofibroblasts. This process is a hallmark of venous neointimal hyperplasia (VNH) associated with hemodialysis vascular access. The purpose of this study was to determine if blood outgrowth en...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000369929

    authors: Nieves Torres EC,Yang B,Brahmbhatt A,Mukhopadhyay D,Misra S

    更新日期:2014-01-01 00:00:00

  • Notch4 Signaling Pathway of Endothelial Progenitor Cells in a Kawasaki Disease Model Induced by Lactobacillus casei Cell Wall Extract.

    abstract::The Notch4 signaling pathway of endothelial progenitor cells (EPCs) may play a crucial role in Kawasaki disease (KD). We investigated the proliferation, adhesion, migration, angiogenesis, and expression levels of Notch4, recombination signal-binding protein-Jκ (RBP-Jκ), P-selectin, and vascular cell adhesion molecule-...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000449061

    authors: Wang H,Xia Y,Fu S,Wang W,Xie C,Zhang Y,Gong F

    更新日期:2016-01-01 00:00:00

  • Endothelial modulation of ouabain-induced contraction and sodium pump activity in aortas of normotensive Wistar-Kyoto and spontaneously hypertensive rats.

    abstract::The influence of vascular endothelium on ouabain-induced contractions and sodium pump activity in aortic segments of Wistar-Kyoto (WKY) and spontaneously hypertensive rat (SHR) was analyzed. De-endothelialization increased and reduced ouabain-induced contractions in WKY and SHR segments, respectively. The effects of d...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000159145

    authors: Ponte A,Marín J,Arribas S,González R,Barrús MT,Salaices M,Sánchez-Ferrer CF

    更新日期:1996-03-01 00:00:00

  • Temporal aspects of Ca(2+) and myosin phosphorylation during myogenic and norepinephrine-induced arteriolar constriction.

    abstract::Previous studies demonstrated that maintenance of steady-state myogenic tone requires Ca(2+)-dependent myosin phosphorylation. The present studies furthered these observations by examining temporal relationships among Ca(2+), myosin phosphorylation and vessel diameter during acute increases in intraluminal pressure an...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000054089

    authors: Zou H,Ratz PH,Hill MA

    更新日期:2000-11-01 00:00:00

  • Plasminogen activator expression correlates with genetic differences in vascular remodeling.

    abstract::Intima-media thickening (IMT) of the carotid artery, a form of vascular remodeling, correlates well with coronary artery disease risk in humans. Vascular remodeling in response to blood flow is a complex process that critically involves altered cell matrix interactions. To gain insight into these events, we performed ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000081804

    authors: Korshunov VA,Solomatina MA,Plekhanova OS,Parfyonova YV,Tkachuk VA,Berk BC

    更新日期:2004-11-01 00:00:00

  • Mechanism of VEGF-induced uterine venous hyperpermeability.

    abstract:BACKGROUND:Transfer of molecular signals from veins to adjacent arteries is an established mechanism of vascular communication in the uterine circulation, which ultimately depends on venous permeability. This study tests the hypotheses that: (1) uterine veins are permeable to intravenous solutes, using a 3-kDa dextran ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000082976

    authors: Celia G,Osol G

    更新日期:2005-01-01 00:00:00

  • Does the endothelium abolish or promote arterial vasomotion in rat mesenteric arteries? Explanations for the seemingly contradictory effects.

    abstract:BACKGROUND AND AIMS:Vasomotion consists in cyclic oscillations of the arterial diameter induced by the synchronized activity of the smooth muscle cells. So far, contradictory results have emerged in the literature about the role of the endothelium in the onset and maintenance of vasomotion. Here our aim is to understan...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000124283

    authors: Seppey D,Sauser R,Koenigsberger M,Bény JL,Meister JJ

    更新日期:2008-01-01 00:00:00

  • Cardiovascular protective effects of synthetic isoflavone derivatives in apolipoprotein e-deficient mice.

    abstract::Dietary flavonoids are thought to protect against cardiovascular disease. We have studied the effects of bioactive isoflavone metabolites on hyperlipidemia, endothelial dysfunction and the development of atherosclerotic lesions in apolipoprotein E-deficient (apoE(0)) mice fed a Western high-fat diet. Supplementation w...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000071891

    authors: Jiang F,Jones GT,Husband AJ,Dusting GJ

    更新日期:2003-05-01 00:00:00

  • Visualization of activated platelets by targeted magnetic resonance imaging utilizing conformation-specific antibodies against glycoprotein IIb/IIIa.

    abstract::Ruptured atherosclerotic plaques, lined with activated platelets, constitute an attractive target for magnetic resonance imaging (MRI). This study evaluated whether microparticles of iron oxide (MPIO) targeting ligand-induced binding sites (LIBS) on the activated conformation of glycoprotein IIb/IIIa could be used to ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000135660

    authors: von zur Muhlen C,Peter K,Ali ZA,Schneider JE,McAteer MA,Neubauer S,Channon KM,Bode C,Choudhury RP

    更新日期:2009-01-01 00:00:00

  • The Cytoscan Model E-II, a new reflectance microscope for intravital microscopy: comparison with the standard fluorescence method.

    abstract::The Cytoscan Model E-II (Cytometrics Inc., Philadelphia, Pa., USA) is a newly developed instrument which functions as an intravital microscope and is small and easily portable. Through the use of orthogonal polarization spectral (OPS) imaging, the Cytoscan Model E-II delivers images of the microcirculation which are c...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000054079

    authors: Harris AG,Sinitsina I,Messmer K

    更新日期:2000-11-01 00:00:00

  • Adaptation of hindquarter vascular reactivity to femoral artery ligation and hypercholesterolemia in the rabbit.

    abstract:AIMS:The effects of ischemia and hypercholesterolemia on the function and morphological adaptation of the rabbit hindlimb were assessed. METHODS:In rabbits on normal or cholesterol diet, experiments were performed on days 0-28 following bilateral femoral artery ligation. Calf blood pressure (C(BP)), exercise tolerance...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000113600

    authors: Wafai R,Angus JA,Wright CE

    更新日期:2008-01-01 00:00:00

  • Actions of platelet-activating factor on isolated rabbit basilar artery: modulation by activated polymorphonuclear leukocytes.

    abstract::In segments of rabbit basilar artery (BA) platelet-activating factor (PAF) initiated a concentration-dependent transitory contraction which was unaffected by indomethacin or nordihydroguaiaretic acid (NDGA). N omega-nitro-L-arginine (NLA) did not change the magnitude of PAF-induced contraction, but in the presence of ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000159077

    authors: Akopov SE,Sercombe R,Seylaz J

    更新日期:1995-01-01 00:00:00

  • Pial microvascular responses to transient bilateral common carotid artery occlusion: effects of hypertonic glycerol.

    abstract:OBJECTIVE:The aim of the study was to assess the rat pial microvessel alterations due to transient bilateral common carotid artery occlusion (BCCAO) and to investigate the mechanism of 10% hypertonic glycerol neuroprotection. Our suggestion was that 10% glycerol solution infusion could dilate pial arterioles through ni...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000109818

    authors: Lapi D,Marchiafava PL,Colantuoni A

    更新日期:2008-01-01 00:00:00

  • Remodeling of Wall Mechanics and the Myogenic Mechanism of Rat Intramural Coronary Arterioles in Response to a Short-Term Daily Exercise Program: Role of Endothelial Factors.

    abstract:PURPOSE:Exercise elicits early adaptation of coronary vessels enabling the coronary circulation to respond adequately to higher flow demands. We hypothesized that short-term daily exercise induces biomechanical and functional remodeling of the coronary resistance arteries related to pressure. METHODS:Male rats were su...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000486571

    authors: Szekeres M,Nádasy GL,Dörnyei G,Szénási A,Koller A

    更新日期:2018-01-01 00:00:00

  • Protective Function of Ahnak1 in Vascular Healing after Wire Injury.

    abstract:AIM:Vascular remodeling following injury substantially accounts for restenosis and adverse clinical outcomes. In this study, we investigated the role of the giant scaffold protein Ahnak1 in vascular healing after endothelial denudation of the murine femoral artery. METHODS:The spatiotemporal expression pattern of Ahna...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000464287

    authors: Haase N,Rüder C,Haase H,Kamann S,Kouno M,Morano I,Dechend R,Zohlnhöfer D,Haase T

    更新日期:2017-01-01 00:00:00

  • Both ICAM-1- and VCAM-1-integrin interactions are important in mediating monocyte adhesion to human saphenous vein.

    abstract::Atherosclerosis underlies late occlusion of human saphenous vein (HSV) coronary artery bypass grafts. Monocyte infiltration is implicated, but its mechanisms are unclear given that HSV normally expresses the ICAM-1 but not the VCAM-1 adhesion molecule. To define the mechanisms underlying monocyte adhesion, samples of ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000063687

    authors: Crook MF,Southgate KM,Newby AC

    更新日期:2002-05-01 00:00:00

  • Transglutaminase 2 deficiency decreases plaque fibrosis and increases plaque inflammation in apolipoprotein-E-deficient mice.

    abstract:AIM:Transglutaminase 2 (TG2) is important for the deposition and stability of the extracellular matrix via effects on cross-linking of matrix proteins and transforming growth factor beta (TGFbeta) activity. The purpose of this study was to investigate the effect of TG2 deficiency on the composi- tion of atherosclerotic...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000255966

    authors: Van Herck JL,Schrijvers DM,De Meyer GR,Martinet W,Van Hove CE,Bult H,Vrints CJ,Herman AG

    更新日期:2010-01-01 00:00:00

  • Heterogeneous distribution of [3H]alpha,beta-methylene ATP binding sites in blood vessels.

    abstract::A radioligand binding assay and autoradiographic localisation of P2X-purinoceptors were carried out in several different blood vessels from rat, guinea-pig and rabbit by using [3H]alpha,beta-methylene ATP ([3H]alpha,beta-MeATP) as the radioligand. The radioligand binding assay on rabbit ear artery showed that the bind...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000158980

    authors: Bo X,Burnstock G

    更新日期:1993-03-01 00:00:00

  • Lipopolysaccharide-induced cytokine and chemokine expression in human carotid lesions.

    abstract::The release of cytokines and chemokines from activated immune-competent cells plays a crucial role in determining the pathology of the atherogenic progress. We investigated the effect of bacterial lipopolysaccharide (LPS) on cytokine/chemokine expression in carotid lesions and normal renal arteries. The lesions or ren...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000085721

    authors: Jatta K,Wågsäter D,Norgren L,Stenberg B,Sirsjö A

    更新日期:2005-05-01 00:00:00

  • Human vascular reactivity and polymorphisms of the angiotensin-converting enzyme and the angiotensin type 1 receptor genes.

    abstract::The D allele of the insertion (I)/deletion (D) polymorphism in the angiotensin-converting enzyme (ACE) gene and the C allele of the A1166-C polymorphism in the angiotensin II type 1 receptor (AGT1R) gene have been associated with altered vascular structure and with an increased risk of myocardial infarction. The aim o...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000025687

    authors: Steeds RP,Toole LO,Channer KS,Morice AH

    更新日期:1999-11-01 00:00:00

  • Connexin channel-dependent signaling pathways in inflammation.

    abstract::Inflammation is a highly regulated process with common but also specific characteristics in each tissue affected. Recruitment of leukocytes from the blood to the injured tissue is an important early step in the inflammatory cascade. This review highlights the role of connexins (Cxs) in the regulation of both acute and...

    journal_title:Journal of vascular research

    pub_type: 杂志文章,评审

    doi:10.1159/000316942

    authors: Scheckenbach KE,Crespin S,Kwak BR,Chanson M

    更新日期:2011-01-01 00:00:00

  • Visualization of leukocyte transendothelial and interstitial migration using reflected light oblique transillumination in intravital video microscopy.

    abstract::Dynamic visualization of the intravascular events leading to the extravasation of leukocytes into tissues by intravital microscopy has significantly expanded our understanding of the underlying molecular processes. In contrast, the detailed observation of leukocyte transendothelial and interstitial migration in vivo h...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000073902

    authors: Mempel TR,Moser C,Hutter J,Kuebler WM,Krombach F

    更新日期:2003-09-01 00:00:00

  • Localization of dopamine receptors in the rabbit lung vasculature.

    abstract::The localization of dopamine receptor subtypes in the rabbit pulmonary circulation was investigated by using combined radioligand binding and light microscope autoradiography techniques. Dopamine D1-like receptors, probably belonging to the dopamine D1 receptor subtype, were demonstrated in sections of rabbit lung usi...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000159094

    authors: Kobayashi Y,Ricci A,Amenta F,Cavallotti C,Hattori K

    更新日期:1995-05-01 00:00:00