Hyperglycosylated hCG.

abstract：OBJECTIVES:Prior studies have demonstrated that donor twin survival following treatment of twin-twin transfusion syndrome (TTTS) was highly associated with donor intrauterine growth restriction (IUGR). Here, we hypothesized that donor IUGR may be attributed in part to low placental share. STUDY DESIGN:The study popula...

journal_title：Placenta

authors： Grubbs BH,Benirschke K,Korst LM,Llanes A,Yedigarova L,Chmait RH

更新日期：2011-08-01 00:00:00

abstract：:The uptake of [3H]choline and its conversion to [3H]acetylcholine were investigated in term human placental tissue in vitro. Although the net uptake of [3H]choline increased throughout a 45 min incubation period, intracellular [3H]choline levels reach a plateau after 2 min. There was a constant increase in [3H]acetylc...

journal_title：Placenta

authors： Leventer SM,Rowell PP

更新日期：1984-05-01 00:00:00

abstract：:Antigen expression by villous and extravillous human trophoblast populations at discrete anatomical sites has been reviewed. The various different antigenic phenotypes have been highlighted using a panel of monoclonal antibodies reactive with characteristic trophoblast membrane antigens, a trophoblast-leucocyte common...

journal_title：Placenta

authors： Bulmer JN,Johnson PM

更新日期：1985-03-01 00:00:00

abstract：:Placental hypoxia as a result of impaired trophoblast invasion is suggested to be involved in the pathophysiology of preeclampsia. Hypoxia is a potent stimulus for the release of adenosine, and the actions of adenosine are mediated through four adenosine receptors, A(1), A(2A), A(2B) and A(3). We investigated the pres...

journal_title：Placenta

authors： von Versen-Höynck F,Rajakumar A,Bainbridge SA,Gallaher MJ,Roberts JM,Powers RW

更新日期：2009-05-01 00:00:00

abstract：:Ovarian, endometrial and breast cancers are associated with several risk factors, such as low parity, infertility, early age at menarche, and late age at menopause. Frequently most of these risk factors coexist in infertile patients and some studies suggested that the different infertility causes can be involved in ca...

journal_title：Placenta

authors： Cetin I,Cozzi V,Antonazzo P

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:During a pregnancy complicated by diabetes, the human placenta undergoes a number of functional and structural pathologic changes, such as increased placental weight and increased incidence of placental lesions including villous maturational defects and fibrinoid necrosis. The pathologic findings reported ...

journal_title：Placenta

authors： Huynh J,Dawson D,Roberts D,Bentley-Lewis R

更新日期：2015-02-01 00:00:00

abstract：:The placenta is a complex and poorly understood organ, which serves as the connection between the mother and the developing fetus. Genomic imprinting, defined as a regulatory process resulting in the expression of a gene in a parent-of-origin-specific manner, plays an important role in fetal development and placental ...

journal_title：Placenta

authors： Rhon-Calderon EA,Vrooman LA,Riesche L,Bartolomei MS

更新日期：2019-09-01 00:00:00

abstract：:Respiratory parameters were studied in mitochondria from human placenta. Respiratory control and ADP/O ratios were low in this preparation. The adenine nucleotide content of placental mitochondria was found to be only one quarter of that found for adult uterine muscle tissue mitochondria prepared in the same way. Load...

journal_title：Placenta

authors： Illsley NP,Coade SB,Harkness RA

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether DNA-associated micro-particles (MPs) in maternal plasma express fetal-derived human leukocyte antigen-G (HLA-G) or placental alkaline phosphatase (PLAP) and whether the levels differ between women with normotensive pregnancies and preeclampsia. METHODS:DNA-asso...

journal_title：Placenta

authors： Orozco AF,Jorgez CJ,Ramos-Perez WD,Popek EJ,Yu X,Kozinetz CA,Bischoff FZ,Lewis DE

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Adverse effects of obesity have been linked to inflammation in various tissues, but studies on placental inflammation and obesity have demonstrated conflicting findings. We sought to investigate the influence of pregravid obesity and fetal sex on placental histopathology while controlling for diabetes and hyp...

journal_title：Placenta

authors： Leon-Garcia SM,Roeder HA,Nelson KK,Liao X,Pizzo DP,Laurent LC,Parast MM,LaCoursiere DY

更新日期：2016-02-01 00:00:00

abstract：:Intra-uterine growth restriction (IUGR) is defined by a restriction of fetal growth during gestation. It is a prevalent significant public health problem that jeopardizes neonatal health but also that can have deleterious consequences later in adult life. Cullins constitute a family of seven proteins involved in cell ...

journal_title：Placenta

authors： Gascoin-Lachambre G,Buffat C,Rebourcet R,Chelbi ST,Rigourd V,Mondon F,Mignot TM,Legras E,Simeoni U,Vaiman D,Barbaux S

更新日期：2010-02-01 00:00:00

abstract：:Human chorionic gonadotropin (hCG) is the first hormonal message from the placenta to the mother. It is detectable in maternal blood two days after implantation and behaves like an agonist of LH stimulating progesterone secretion by the corpus luteum. hCG has also a role in quiescence of the myometrium and local immun...

journal_title：Placenta

authors： Fournier T,Guibourdenche J,Evain-Brion D

更新日期：2015-04-01 00:00:00

abstract：:The processes of proliferation, migration, and invasion of extravillous trophoblasts are critical for placental implantation and early development, and directly influence pregnancy outcome. Dysregulation of these processes has been associated with placental dysfunction, implicated in clinical conditions such as preecl...

journal_title：Placenta

authors： Xie L,Sadovsky Y

更新日期：2016-12-01 00:00:00

abstract：:The ability to directly monitor the status of the placenta throughout pregnancy would be a major advance in both general and personalized obstetric care, allowing treatments to be tailored to the dynamic changes that can occur in gestation. Syncytiotrophoblast extracellular vesicles (STBEV) are membrane bound vesicles...

journal_title：Placenta

authors： Tannetta D,Collett G,Vatish M,Redman C,Sargent I

更新日期：2017-04-01 00:00:00

abstract：:TRH immunological and biological activity was characterized in rat placental extracts. Placentae were extracted sequentially with 2 N acetic acid and glacial acetic acid. The lyophilized residues were further extracted with 90 per cent methanol, and the extracts were then dried, and reextracted with distilled water. W...

journal_title：Placenta

authors： Shambaugh GE 3rd,Kubek M,Wilber JF

更新日期：1983-10-01 00:00:00

abstract：INTRODUCTION:Chronic villitis of unknown etiology (CVUE) and massive chronic intervillositis (MCI) are placental lesions associated with infiltration of mononuclear cells in the chorionic villi and the intervillous spaces, respectively. It is not well known whether immune cells in CVUE and MCI have similar phenotypic c...

journal_title：Placenta

authors： Labarrere CA,Hardin JW,Haas DM,Kassab GS

更新日期：2015-06-01 00:00:00

abstract：:Genomic imprinting, which results in the mono-allelic expression of certain genes in a parent of origin-dependent manner, represents a specialized form of gene regulation which may be vitally important for mammalian development. The mechanisms which underlie imprinting and the molecular nature of the imprint itself re...

journal_title：Placenta

authors： Franklin GC,Adam GI,Ohlsson R

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Alloimmunization against human platelet antigens (HPAs) can occur prenatally and induce fetal/neonatal alloimmune thrombocytopenia (FNAIT). The aim of this study was to identify placental histological features associated with platelet alloimmunization and their clinical significance. METHODS:This study exam...

journal_title：Placenta

authors： Dubruc E,Lebreton F,Giannoli C,Rabilloud M,Huissoud C,Devouassoux-Shisheboran M,Allias F

更新日期：2016-12-01 00:00:00

abstract：:Receptors for complexes between alpha 2-macroglobulin (alpha 2M) and proteinases (e.g. trypsin) were identified and characterized in the human placenta. The receptors also bound the complex formed between pregnancy zone protein (PZP) and chymotrypsin, although with slightly lower affinity, whereas binding of alpha 2M ...

journal_title：Placenta

authors： Jensen PH,Moestrup SK,Sottrup-Jensen L,Petersen CM,Gliemann J

更新日期：1988-09-01 00:00:00

abstract：:Embryo implantation in the human and rodents relies on the trophoblast's ability to invade into the uterine stroma, partly depending on proteinases degrading components of basement membrane and underlying extracellular matrix (ECM). We have utilized mouse trophoblast stem (TS) cells (Science, 1998, 282:2072) to study ...

journal_title：Placenta

authors： Lei T,Hohn HP,Behr R,Denker HW

更新日期：2007-01-01 00:00:00

abstract：:Dietary taurine is essential for cats and deficiency during pregnancy may lead to abortion, growth restriction or impaired neurological function of kittens. We previously described Na(+)- and Cl(-)-dependent taurine transport by system beta in fragments of freshly isolated cat placenta [Champion EE, Bailey SJ, Glazier...

journal_title：Placenta

authors： Champion EE,Mann SJ,Glazier JD,Jones CJ,Rawlings JM,Sibley CP,Greenwood SL

更新日期：2005-09-01 00:00:00

abstract：:In the present study the possible role of decidual cells in the pregnancy-associated increased sensitivity of glomerular ecto-ADP-ase to endotoxin was investigated. Early (day 5) pregnant (E-Pr; n = 10), pseudopregnant (E-PSP; n = 10), (day 5), pseudopregnant rats with a decidualized uterus (E-DEC; n - 10), as well as...

journal_title：Placenta

authors： Faas MM,Schuiling GA,Baller JF,Valkhof N,Bakker WW

更新日期：1996-03-01 00:00:00

abstract：:The possible roles of the allantoic sac in metabolism of uteroferrin, the iron-containing, purple phosphatase, were examined. This protein, which originates in the maternal endometrium, was measured in allantoic fluid by a specific double-antibody radioimmunoassay and by its beta-mercaptoethanol-activated acid phospha...

journal_title：Placenta

authors： Buhi WC,Ducsay CA,Bartol FF,Bazer FW,Roberts RM

更新日期：1983-01-01 00:00:00

abstract：INTRODUCTION:Feeding pregnant broodmares with cereal concentrates has been shown to increase maternal insulin resistance and affect foal metabolism in the short and long-term. These effects are likely to be mediated by the placenta. Here, we investigated feto-placental biometry and placental structure and function at t...

journal_title：Placenta

authors： Robles M,Peugnet P,Dubois C,Piumi F,Jouneau L,Bouchez O,Aubrière MC,Dahirel M,Aioun J,Wimel L,Couturier-Tarrade A,Chavatte-Palmer P

更新日期：2018-04-01 00:00:00

abstract：:Previous studies have shown that human and mouse placentas have hematopoietic potential during mid-gestation. In this investigation, we used histological and immunohistological approaches to visualize hematopoietic cells in mouse placenta between 9.5 and 12.5 days of gestation (gd), identifying their topography and ni...

journal_title：Placenta

authors： Azevedo Portilho N,Tavares Guedes P,Croy BA,Pelajo-Machado M

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To examine the expression of multifunctional Na(+)-independent organic anion transporting polypeptide, termed OATP-E, involved in the transport of thyroid hormone in human placenta. METHODS:Western blot analysis was performed using a specific antibody against OATP-E in human placenta to confirm the expression ...

journal_title：Placenta

authors： Sato K,Sugawara J,Sato T,Mizutamari H,Suzuki T,Ito A,Mikkaichi T,Onogawa T,Tanemoto M,Unno M,Abe T,Okamura K

更新日期：2003-02-01 00:00:00

abstract：INTRODUCTION:Hypotaurine is a precursor of taurine and an antioxidant, and is concentrated in fetal plasma compared to maternal plasma. Hypotaurine is significantly decreased in fetal plasma of ezrin (Vil2) knock-out mice, and fetuses show intrauterine growth retardation. The aim of this study was to characterize the m...

journal_title：Placenta

authors： Nishimura T,Duereh M,Sugita Y,Yoshida Y,Higuchi K,Tomi M,Nakashima E

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:Placenta previa is a severe pregnancy complication with considerable maternal and neonatal morbidity. Placenta previa can be defined as major or minor by location. Major placenta previa is associated with higher complication rates. Management of women with minor placenta previa has not been well defined. T...

journal_title：Placenta

authors： Grönvall M,Stefanovic V,Paavonen J,Loukovaara M,Tikkanen M

更新日期：2019-09-15 00:00:00

abstract：:Approximately 6 per cent of placentae of babies admitted to a special care paediatric unit show evidence of peripheral villous stem branch oedema. In more than half of these cases there is evidence of fibrinous vasculosis (FV) in truncal veins. The affected placentae are generally thick and of small diameter, often of...

journal_title：Placenta

authors： Scott JM

更新日期：1983-01-01 00:00:00

abstract：:We have previously shown that thioredoxin and thioredoxin reductase were immunohistochemically localized in cytotrophoblasts, decidua and stromal cells in the stem villi of human placenta and that the addition of exogenous thioredoxin and thioredoxin reductase to mitochondrial fractions from human placenta displayed a...

journal_title：Placenta

authors： Ejima K,Koji T,Nanri H,Kashimura M,Ikeda M

更新日期：1999-09-01 00:00:00