Genomic imprinting and mammalian development.

abstract：:Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialised topics. At IFPA meeting 2013 there were twelve themed workshops, three of which are summarized in this report. These workshops related to various aspects of placental biology but collectively covered areas of placent...

journal_title：Placenta

authors： Abumaree MH,Brownbill P,Burton G,Castillo C,Chamley L,Croy BA,Drewlo S,Dunk C,Girard S,Hansson S,Jones S,Jurisicova A,Lewis R,Letarte M,Parast M,Pehrson C,Rappolee D,Schneider H,Tannetta D,Varmuza S,Wadsack C,Wa

更新日期：2014-02-01 00:00:00

abstract：:Fetal growth restriction (FGR) is the failure of a fetus to reach its full genetic growth potential. It occurs in up to 8% of pregnancies, and after premature birth is the second leading cause of infant mortality and morbidity. There is no treatment currently available for FGR. Its primary cause, when not attributable...

journal_title：Placenta

authors： Swanson AM,David AL

更新日期：2015-06-01 00:00:00

abstract：:Human amniotic epithelium from patients with normal pregnancy (normal amniotic epithelium) and from patients with materno-fetal rhesus incompatibility has been examined under the light and electron microscope. In comparison with normal amniotic epithelium, the epithelium in rhesus incompatibility displays the followin...

journal_title：Placenta

authors： Wang T

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVES:Microbial-specific factors are likely critical in determining whether bacteria trigger preterm labor. Structural variations in lipopolysaccharide (LPS), a component of gram-negative bacteria, can determine whether LPS has an inflammatory (agonist) or anti-inflammatory (antagonist) effect through Toll-like re...

journal_title：Placenta

authors： Chang J,Jain S,Carl DJ,Paolella L,Darveau RP,Gravett MG,Adams Waldorf KM

更新日期：2010-09-01 00:00:00

abstract：:Preeclampsia is a leading cause of maternal and fetal morbidity and mortality in high and low-income countries. The aetiology of preeclampsia is multifactorial and remains obscure. Some evidences suggest that altered placental fatty acid oxidation might play a role in the pathogenesis of preeclampsia. To reveal if pla...

journal_title：Placenta

authors： Bartha JL,Visiedo F,Fernández-Deudero A,Bugatto F,Perdomo G

更新日期：2012-02-01 00:00:00

abstract：:Chorioallantoic placentae were obtained from a reproductively synchronized wild population of greater mustache bats for ultrastructural and immunocytochemical examination. The single discoidal placenta was always located in a lateral to mesometrial position on the right side of the uterus, which in the non-pregnant st...

journal_title：Placenta

authors： Badwaik NK,Rasweiler JJ 4th

更新日期：1998-07-01 00:00:00

abstract：:Placentae from both smoking and non-smoking mothers were studied with respect to P450-dependent xenobiotic and steroid-metabolizing reactions, GSHt activity with different substrates and umbilical blood cotinine levels. Catalytic activities were determined in both freshly prepared homogenate subfractions and subfracti...

journal_title：Placenta

authors： Pasanen M,Pelkonen O

更新日期：1990-01-01 00:00:00

abstract：:The transport of large amounts of Ca2+ by the plasma membranes of human placental syncytiotrophoblast is essential to the mineralization of the growing fetal skeleton. We have investigated transport by the basal (fetal-facing) plasma membrane (BPM). Ca2+ was taken up by purified BPM vesicles in a time-dependent manner...

journal_title：Placenta

authors： Kamath SG,Haider N,Smith CH

更新日期：1994-02-01 00:00:00

abstract：:The aim of our work was to investigate the presence of non-selective cation channels (NSCC) in freshly isolated smooth muscle cells from the human umbilical artery (HUA), one of the vessels involved in fetal-placental circulation. We studied the electrophysiological properties of NSCC using the patch-clamp technique i...

journal_title：Placenta

authors： Raingo J,Rebolledo A,Iveli F,Grassi de Gende AO,Milesi V

更新日期：2004-09-01 00:00:00

abstract：INTRODUCTION:Statins induce heme oxygenase-1 (HO-1) expression in vitro and in vivo. Low HO-1 expression is associated with pregnancy complications, e.g. preeclampsia and recurrent miscarriages. Here, we investigated the effects of pravastatin on HO-1 expression, placental development, and fetal survival in mice with a...

journal_title：Placenta

authors： Tsur A,Kalish F,Burgess J,Nayak NR,Zhao H,Casey KM,Druzin ML,Wong RJ,Stevenson DK

更新日期：2019-01-01 00:00:00

abstract：:Telomeres are nucleoprotein structures located at the termini of chromosomes. They are essential for chromosome stability. Telomeres become shorter due to mitotic cycles and environmental factors. When telomeres are shortened and therefore dysfunctional, cellular senescence occurs and organ dysfunction might develop. ...

journal_title：Placenta

authors： Biron-Shental T,Sadeh-Mestechkin D,Amiel A

更新日期：2016-03-01 00:00:00

abstract：:Preterm birth is a leading cause of child morbidity and mortality, so strategies to reduce early birth must remain a priority. One key approach to enhancing birth outcomes is improving maternal dietary intake. Therefore, the purpose of this review is to discuss mechanisms on perinatal status of fat-soluble nutrients (...

journal_title：Placenta

authors： Thoene M,Van Ormer M,Yuil-Valdes A,Bruett T,Natarajan SK,Mukherjee M,Thompson M,Nordgren TM,Van Lippevelde W,Overby NC,Adu-Bonsaffoh K,Anderson-Berry A,Hanson C

更新日期：2020-09-01 00:00:00

abstract：:Maternal diabetes affects the development of the offspring by altering the uterine environment. We aimed to investigate the extent to which the blood flow (measured as Tissue Perfusion Units; TPU) to implantation sites and the expression of developmentally important genes in the offspring are affected by maternal diab...

journal_title：Placenta

authors： Zabihi S,Wentzel P,Eriksson UJ

更新日期：2008-05-01 00:00:00

abstract：:Intra-uterine growth restriction (IUGR) is defined by a restriction of fetal growth during gestation. It is a prevalent significant public health problem that jeopardizes neonatal health but also that can have deleterious consequences later in adult life. Cullins constitute a family of seven proteins involved in cell ...

journal_title：Placenta

authors： Gascoin-Lachambre G,Buffat C,Rebourcet R,Chelbi ST,Rigourd V,Mondon F,Mignot TM,Legras E,Simeoni U,Vaiman D,Barbaux S

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:Preeclampsia is characterized by maternal endothelial dysfunction. While the mechanisms leading to preeclampsia are unclear, a factor(s) from the placenta is responsible for triggering the disease. One placental factor implicated in triggering preeclampsia is trophoblast debris which may transmit pathogeni...

journal_title：Placenta

authors： Shen F,Wei J,Snowise S,DeSousa J,Stone P,Viall C,Chen Q,Chamley L

更新日期：2014-10-01 00:00:00

abstract：:Placental protein 5 (PP5)/tissue factor pathway inhibitor-2 (TFPI-2), a serine proteinase inhibitor, is homologous to tissue factor pathway inhibitor (TFPI) and commonly found in peripheral blood of pregnant woman. Although TFPI is well known to be synthesized primarily in endothelium and to play an important role in ...

journal_title：Placenta

authors： Udagawa K,Yasumitsu H,Esaki M,Sawada H,Nagashima Y,Aoki I,Jin M,Miyagi E,Nakazawa T,Hirahara F,Miyazaki K,Miyagi Y

更新日期：2002-02-01 00:00:00

abstract：:A long and productive history of studies at high altitude has demonstrated that chronic hypoxia plays a key role in the aetiology of intrauterine growth restriction (IUGR) and pre-eclampsia. Susceptibility to altitude-associated IUGR varies among high-altitude populations in relation to their duration of altitude expo...

journal_title：Placenta

authors： Moore LG,Shriver M,Bemis L,Hickler B,Wilson M,Brutsaert T,Parra E,Vargas E

更新日期：2004-04-01 00:00:00

abstract：:The visceral yolk sac (VYS) is responsible for a major part of the amino acid nutrition of the early post-implantation rat embryo and possibly also at the fetal stage of gestation. The mechanism involves endocytic uptake of proteins by the tissue's epithelial cells followed by intralysosomal digestion to amino acids. ...

journal_title：Placenta

authors： Pratten MK,Lloyd JB

更新日期：1997-09-01 00:00:00

abstract：:The IPL/TSSC3 gene is expressed nearly exclusively from the maternal allele, and its protein product acts to limit placental growth in mice. This protein specifically marks Type II trophoblast in the labyrinthine layer of the mouse placenta. To investigate mouse-human homologies, we carried out immunohistochemistry wi...

journal_title：Placenta

authors： Saxena A,Frank D,Panichkul P,Van den Veyver IB,Tycko B,Thaker H

更新日期：2003-09-01 00:00:00

abstract：:Hofbauer cells have been identified by morphological criteria in human placentae and are considered to be mononuclear phagocytes. An increasing recognition of the morphological heterogeneity of mononuclear phagocytes and of the considerable difficulty in their recognition in histological sections has suggested that th...

journal_title：Placenta

authors： Wood GW

更新日期：1980-04-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to explore serum levels of differentially abundant proteins between women with hypertensive disorders of pregnancy (HDP) and women with normal-term pregnancy, and to explore the contribution of SH3BGRL3 to the pathogenesis of HDP. METHODS:At 6-20 weeks gestation 48 pregnant...

journal_title：Placenta

authors： Jiang M,Lash GE,Zeng S,Liu F,Han M,Long Y,Cai M,Hou H,Ning F,Hu Y,Yang H

更新日期：2020-11-14 00:00:00

abstract：:Placental Site Trophoblastic Tumor (PSTT) is a rare form of Gestational Trophoblastic Disease (GTD). Approximately 200 cases have been reported in the literature. This disease has unpredictable biological behavior, whereas approximately 10-15% have clinically malignant evolution. We present the case of a 21-year old w...

journal_title：Placenta

authors： Colecchi C,Partemi S,Minelli N,Cascini F,Rossi R,Fulcheri E,Pascali VL,Oliva A

更新日期：2011-12-01 00:00:00

abstract：:There is inconsistent use of Matrigel for experiments with the HTR8/SVneo first trimester trophoblast and other cell lines. We quantified the effects of Matrigel on the expression of genes considered to be markers of extravillous cytotrophoblast (EVT) differentiation and invasive potential. Culture on Matrigel promote...

journal_title：Placenta

authors： Highet AR,Zhang VJ,Heinemann GK,Roberts CT

更新日期：2012-07-01 00:00:00

abstract：INTRODUCTION:Type 1 diabetes (T1D) is associated with adverse pregnancy outcome, usually attributed to hyperglycemia. Recently, we showed that pregnancy outcome in normoglycemic T1D rats was characterized by decreased fetal and placental weight, suggesting impaired placental development. In the present study, we tested...

journal_title：Placenta

authors： Groen B,Uuldriks GA,de Vos P,Visser JT,Links TP,Faas MM

更新日期：2015-02-01 00:00:00

abstract：INTRODUCTION:Placental transport is the main factor affecting the health and development of the fetus. Due to the placenta's geometrical and mathematical complexity, the structure-function relations of placental terminal villi have not been successfully modeled. Hence, a novel modeling approach is proposed. METHODS:Co...

journal_title：Placenta

authors： Plitman Mayo R,Charnock-Jones DS,Burton GJ,Oyen ML

更新日期：2016-07-01 00:00:00

abstract：:Phorbol myristate acetate (PMA) and all-trans-retinal (retinal) were evaluated as possible phagocytic stimulators of cultured, post implantation, trophoblast cells. Ectoplacental cones dissected from 7.5 day-old mouse embryos provided the source of trophoblastic cells. Co-cultures were performed using stimulated and n...

journal_title：Placenta

authors： Albieri A,Bevilacqua E

更新日期：1996-09-01 00:00:00

abstract：:Human placental villi are surfaced by an outer multinucleated syncytiotrophoblast and underlying mononucleated cytotrophoblasts. Conflicting data have attributed one, or the other, of these villous trophoblast phenotypes to undergo enhanced apoptosis in complicated pregnancies, compared to term, normotensive pregnanci...

journal_title：Placenta

authors： Longtine MS,Chen B,Odibo AO,Zhong Y,Nelson DM

更新日期：2012-05-01 00:00:00

abstract：:The human placenta contains two types of 11beta-hydroxysteroid dehydrogenase (11beta-HSD). The exclusive oxidase 11beta-HSD2 has been suggested to protect the fetus from high levels of maternal glucocorticoids by converting cortisol to inactive cortisone. Perfused term human placenta was used to examine the activity o...

journal_title：Placenta

authors： Sun K,Adamson SL,Yang K,Challis JR

更新日期：1999-01-01 00:00:00

abstract：:A localized intrauterine inflammatory response is often associated with the initiation of normal human parturition, whereas infection causes a similar but more florid response initiating preterm labor. Pre-B-cell colony-enhancing factor (PBEF) is expressed in the human fetal membranes and is up-regulated by labor, sev...

journal_title：Placenta

authors： Kendal CE,Bryant-Greenwood GD

更新日期：2007-04-01 00:00:00

abstract：INTRODUCTION:Infection accounts for over 40% of preterm premature rupture of the fetal membranes (PPROM), a major cause of preterm birth. Toll-like receptors (TLR) play key roles in pathogen surveillance but their expression and function in amnion mesenchymal cells (AMC) is unclear. The aims of this study were to deter...

journal_title：Placenta

authors： Sato BL,Collier ES,Vermudez SA,Junker AD,Kendal-Wright CE

更新日期：2016-08-01 00:00:00