Placental Site Trophoblastic Tumor with lung metastases as cause of death in a young patient: a case report.

abstract：INTRODUCTION:Placenta previa is a severe pregnancy complication with considerable maternal and neonatal morbidity. Placenta previa can be defined as major or minor by location. Major placenta previa is associated with higher complication rates. Management of women with minor placenta previa has not been well defined. T...

journal_title：Placenta

authors： Grönvall M,Stefanovic V,Paavonen J,Loukovaara M,Tikkanen M

更新日期：2019-09-15 00:00:00

abstract：:Human leukocyte antigen (HLA)-G is a non-classical HLA-class I antigen which is predominantly expressed on invasive trophoblastic cells and is postulated to be a mediator of maternal-fetal tolerance. HLA-G interacts with NK cells, can present nonamer peptides and binds CD8 in an analogous manner to classical HLA-I. Th...

journal_title：Placenta

authors： van der Ven K,Pfeiffer K,Skrablin S

更新日期：2000-03-01 00:00:00

abstract：:Preeclampsia (PE) is a serious pregnancy-related syndrome, which is characterized by gestational hypertension and proteinuria. The microRNA-93 (miR-93) is upregulated in the maternal plasma of patients with PE. However, the functional role of miR-93 in PE remains unknown. Here, we identified that miR-93 inhibits troph...

journal_title：Placenta

authors： Pan Q,Niu H,Cheng L,Li X,Zhang Q,Ning Y

更新日期：2017-05-01 00:00:00

abstract：:Pregnancy-associated placental protein-A (PAPP-A), first isolated from maternal serum, has been identified as a metalloprotease cleaving insulin-like growth factor binding protein-4 (IGFBP-4). The source of PAPP-A during pregnancy is unclear. We therefore investigated PAPP-A expression during in vitro human villous cy...

journal_title：Placenta

authors： Guibourdenche J,Frendo JL,Pidoux G,Bertin G,Luton D,Muller F,Porquet D,Evain-Brion D

更新日期：2003-05-01 00:00:00

abstract：:The placenta is a complex and poorly understood organ, which serves as the connection between the mother and the developing fetus. Genomic imprinting, defined as a regulatory process resulting in the expression of a gene in a parent-of-origin-specific manner, plays an important role in fetal development and placental ...

journal_title：Placenta

authors： Rhon-Calderon EA,Vrooman LA,Riesche L,Bartolomei MS

更新日期：2019-09-01 00:00:00

abstract：:The uterine endometrium responds to blastocyst implantation with extensive proliferation and differentiation of stromal cells into decidual cells, forming the antimesometrial and mesometrial decidua. These undergo regression by apoptosis but as this process occurs at different time periods suggest that there is spatia...

journal_title：Placenta

authors： Correia-da-Silva G,Bell SC,Pringle JH,Teixeira NA

更新日期：2005-11-01 00:00:00

abstract：:Recent studies have indicated that oxidative stress is involved in the pathogenesis of pre-eclampsia. Oxidative stress damages systemic tissues, and placental damage may result in intrauterine growth retardation and fetal distress. Thus, this study attempted to elucidate the placental localization of thioredoxin and t...

journal_title：Placenta

authors： Ejima K,Nanri H,Toki N,Kashimura M,Ikeda M

更新日期：1999-01-01 00:00:00

abstract：:Amniotic fluid exerts a protective function and is an essential component for foetal development and maturation during pregnancy. However, little is known about the exact physiological functions of foetal fluids in this process as well as their biochemical composition in cats. In the present study, the biochemical com...

journal_title：Placenta

authors： Fresno L,Rodriguez-Gil JE,Rigau T,Pastor J,Rivera del Alamo MM

更新日期：2012-06-01 00:00:00

abstract：:Telomeres are nucleoprotein structures located at the termini of chromosomes. They are essential for chromosome stability. Telomeres become shorter due to mitotic cycles and environmental factors. When telomeres are shortened and therefore dysfunctional, cellular senescence occurs and organ dysfunction might develop. ...

journal_title：Placenta

authors： Biron-Shental T,Sadeh-Mestechkin D,Amiel A

更新日期：2016-03-01 00:00:00

abstract：:Decidualization process involves the morphological and functional transformation of endometrial stromal cells into decidual cells. This is a finely regulated process, which involves proliferation and differentiation of stromal cells into decidual cells, which is followed by regression of the decidual tissue, mainly by...

journal_title：Placenta

authors： Fonseca BM,Teixeira NA,Almada M,Taylor AH,Konje JC,Correia-da-Silva G

更新日期：2011-06-01 00:00:00

abstract：:Respiratory parameters were studied in mitochondria from human placenta. Respiratory control and ADP/O ratios were low in this preparation. The adenine nucleotide content of placental mitochondria was found to be only one quarter of that found for adult uterine muscle tissue mitochondria prepared in the same way. Load...

journal_title：Placenta

authors： Illsley NP,Coade SB,Harkness RA

更新日期：1985-05-01 00:00:00

abstract：INTRODUCTION:Chronic histiocytic intervillositis of unknown etiology (CIUE) is a rare placental lesion characterized by an intervillous mononuclear inflammatory infiltrate of maternal origin. Although the mechanism and origin of these lesions are currently not understood, they appear to be related to an immune conflict...

journal_title：Placenta

authors： Capuani C,Meggetto F,Duga I,Danjoux M,March M,Parant O,Brousset P,Aziza J

更新日期：2013-02-01 00:00:00

abstract：:Recent demonstrations of transferrin (TF) mRNA in placental tissue raised the possibility that the placenta may serve as an extra-hepatic source of this iron-binding protein during development. In this study, we first confirmed these findings using cRNA probes for TF, and then adapted the TF reverse haemolytic plaque ...

journal_title：Placenta

authors： Boockfor FR,Harris SE,Barto JM,Bonner JM

更新日期：1994-07-01 00:00:00

abstract：INTRODUCTION:Abnormally invasive placenta (AIP) is a rare pregnancy complication often resulting in postpartum haemorrhage (PPH) and emergency peripartum hysterectomy (EPH). The risk of developing post traumatic stress disorder (PTSD) following unexpectedly traumatic childbirth is known however there is no evidence reg...

journal_title：Placenta

authors： Tol ID,Yousif M,Collins SL

更新日期：2019-06-01 00:00:00

abstract：:Corticotrophin-releasing factor (CRF) immunoreactivity was demonstrated by immunohistochemical staining in the cytotrophoblast of the early pregnancy placenta, in the decidua and in the amnion. This localization is different from that of adrenocorticotrophic hormone (ACTH) and beta-endorphin, which are present in the ...

journal_title：Placenta

authors： Saijonmaa O,Laatikainen T,Wahlström T

更新日期：1988-07-01 00:00:00

abstract：INTRODUCTION:The limited cell number of primary trophoblasts and contamination of trophoblast cell lines promote us to develop a novel stable trophoblast cell line. METHOD OF STUDY:Primary trophoblast cells were isolated from first-trimester placenta and telomerase-induced immortalization was used to immortalize these...

journal_title：Placenta

authors： Liu H,Wang L,Wang Y,Zhu Q,Aldo P,Ding J,Mor G,Liao A

更新日期：2020-10-01 00:00:00

abstract：:Throughout its entire lifespan, the placenta is able to produce as well as respond to a variety of inflammatory stimuli. Many signaling molecules and concurrent pathways responsible for the propagation of an inflammatory response have been identified in placental cells. From early developmental stages onward, the secr...

journal_title：Placenta

authors： Hauguel-de Mouzon S,Guerre-Millo M

更新日期：2006-08-01 00:00:00

abstract：:A long and productive history of studies at high altitude has demonstrated that chronic hypoxia plays a key role in the aetiology of intrauterine growth restriction (IUGR) and pre-eclampsia. Susceptibility to altitude-associated IUGR varies among high-altitude populations in relation to their duration of altitude expo...

journal_title：Placenta

authors： Moore LG,Shriver M,Bemis L,Hickler B,Wilson M,Brutsaert T,Parra E,Vargas E

更新日期：2004-04-01 00:00:00

abstract：:Indiscriminate invasion upon the endometrium by normal trophoblasts is strictly regulated unlike that by choriocarcinoma cells. In this study, we focused on the activity of matrix metalloproteinase (MMP)-2 and MMP-9 as parameters of invasion in normal human placenta. In situ hybridization (ISH), immunohistochemical st...

journal_title：Placenta

authors： Isaka K,Usuda S,Ito H,Sagawa Y,Nakamura H,Nishi H,Suzuki Y,Li YF,Takayama M

更新日期：2003-01-01 00:00:00

abstract：:Embryo implantation in the human and rodents relies on the trophoblast's ability to invade into the uterine stroma, partly depending on proteinases degrading components of basement membrane and underlying extracellular matrix (ECM). We have utilized mouse trophoblast stem (TS) cells (Science, 1998, 282:2072) to study ...

journal_title：Placenta

authors： Lei T,Hohn HP,Behr R,Denker HW

更新日期：2007-01-01 00:00:00

abstract：:Genomic imprinting, which results in the mono-allelic expression of certain genes in a parent of origin-dependent manner, represents a specialized form of gene regulation which may be vitally important for mammalian development. The mechanisms which underlie imprinting and the molecular nature of the imprint itself re...

journal_title：Placenta

authors： Franklin GC,Adam GI,Ohlsson R

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Discrepancies in the results from studies of early events in human trophoblast invasion of decidua have been acknowledged and are attributed largely to deficiencies in the accuracy of sampling of the decidual tissue used in the research. We describe a novel technique of biopsy of decidua parietalis and basal...

journal_title：Placenta

authors： Talaulikar VS,Bax BE,Page NM,Manyonda I

更新日期：2012-06-01 00:00:00

abstract：:Maternal diabetes affects the development of the offspring by altering the uterine environment. We aimed to investigate the extent to which the blood flow (measured as Tissue Perfusion Units; TPU) to implantation sites and the expression of developmentally important genes in the offspring are affected by maternal diab...

journal_title：Placenta

authors： Zabihi S,Wentzel P,Eriksson UJ

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To examine the expression of multifunctional Na(+)-independent organic anion transporting polypeptide, termed OATP-E, involved in the transport of thyroid hormone in human placenta. METHODS:Western blot analysis was performed using a specific antibody against OATP-E in human placenta to confirm the expression ...

journal_title：Placenta

authors： Sato K,Sugawara J,Sato T,Mizutamari H,Suzuki T,Ito A,Mikkaichi T,Onogawa T,Tanemoto M,Unno M,Abe T,Okamura K

更新日期：2003-02-01 00:00:00

abstract：:Glycogen storage disease type IV (GSD IV) is a rare autosomal recessive disorder caused by glycogen branching enzyme (GBE) deficiency and resulting in the storage of abnormal glycogen (polyglucosan). Prenatal diagnosis is based on biochemical assay of GBE activity or on mutation analysis, but polyglucosan can also be ...

journal_title：Placenta

authors： Konstantinidou AE,Anninos H,Dertinger S,Nonni A,Petersen M,Karadimas C,Havaki S,Marinos E,Akman HO,DiMauro S,Patsouris E

更新日期：2008-04-01 00:00:00

abstract：:Placental villi of early and term human placentae were dissociated with trypsin and mixed cell cultures were established. The different cell types were identified and estimated over a 14-day culture period using antibodies to keratin and vimentin filaments and their capacity to phagocytose yeast. The three main cell t...

journal_title：Placenta

authors： Contractor SF,Routledge A,Sooranna SR

更新日期：1984-01-01 00:00:00

abstract：:In primates and rodents, trophoblast cells synthesize and secrete into the maternal circulation a family of proteins known as pregnancy specific glycoproteins (PSG). The current study was undertaken to characterize the receptor for two members of the murine PSG family, PSG17 and PSG23. Binding of recombinant PSG17 and...

journal_title：Placenta

authors： Sulkowski GN,Warren J,Ha CT,Dveksler GS

更新日期：2011-08-01 00:00:00

abstract：:During early pregnancy, intermediate (extravillous) trophoblast infiltrates the basal plate and invades the spiral arteries, a physiological process required to establish the maternal-fetal circulation. Immunostaining studies have shown that differentiation of trophoblast into this invasive subpopulation is associated...

journal_title：Placenta

authors： Shih IeM,Hsu MY,Oldt RJ 3rd,Herlyn M,Gearhart JD,Kurman RJ

更新日期：2002-11-01 00:00:00

abstract：:Placental vascular tone is critically influenced by nitric oxide (NO) derived from endothelial NO synthase (eNOS) activity. Placental vessels from pregnancies complicated with intrauterine growth restriction present altered NOS-dependent vasodilation. Arginase-2 competes with eNOS for l-arginine and counteracts the NO...

journal_title：Placenta

authors： Krause BJ,Carrasco-Wong I,Caniuguir A,Carvajal J,Farías M,Casanello P

更新日期：2013-01-01 00:00:00

abstract：:Glucose residues were revealed by light microscopic and fine structural analysis using hexokinase-gold conjugate. In human term placenta specific staining was detected over the stroma of placental villi. Colloidal gold particles were found over the collagen fibrils and reticular lamina of basal membrane. Syncytiotroph...

journal_title：Placenta

authors： Glazyrin AL,Kolesnikov SI

更新日期：1993-09-01 00:00:00