Expression of organic anion transporting polypeptide E (OATP-E) in human placenta.

abstract：INTRODUCTION:Human decidual stromal cells (DSCs) play a key role in maternal-fetal interactions. Precursors of DSCs (preDSCs) localize around vessels in both the endometrium and decidua. Previous studies suggested a relationship between preDSCs and pericytes because these cells share a perivascular location, alpha smoo...

journal_title：Placenta

authors： Muñoz-Fernández R,de la Mata C,Prados A,Perea A,Ruiz-Magaña MJ,Llorca T,Fernández-Rubio P,Blanco O,Abadía-Molina AC,Olivares EG

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to investigate localization and content of activin beta A-subunit and activin receptors in gestational tissues throughout pregnancy and in association with term labour. Placenta and fetal membranes were collected from women undergoing first and second trimester terminations and from women bef...

journal_title：Placenta

authors： Schneider-Kolsky ME,Manuelpillai U,Waldron K,Dole A,Wallace EM

更新日期：2002-04-01 00:00:00

abstract：INTRODUCTION:The aim of this study is to determine whether the gene expression and associated DNA methylation regulation of H19 and IGF2 are altered in placentas conceived by assisted reproductive technologies (ART) compared to natural conceptions. METHODS:113 pregnancies were recruited resulting in 119 placentas (83 ...

journal_title：Placenta

authors： Sakian S,Louie K,Wong EC,Havelock J,Kashyap S,Rowe T,Taylor B,Ma S

更新日期：2015-10-01 00:00:00

abstract：:Phorbol myristate acetate (PMA) and all-trans-retinal (retinal) were evaluated as possible phagocytic stimulators of cultured, post implantation, trophoblast cells. Ectoplacental cones dissected from 7.5 day-old mouse embryos provided the source of trophoblastic cells. Co-cultures were performed using stimulated and n...

journal_title：Placenta

authors： Albieri A,Bevilacqua E

更新日期：1996-09-01 00:00:00

abstract：:Amino acid transport System A (SysA) activity is present within the rodent and human placentas. Inhibition of this transport system is associated with fetal growth retardation. Several cDNAs encoding SysA transport proteins have been discovered, and their presence documented within the human placenta. We have demonstr...

journal_title：Placenta

authors： Novak D,Lehman M,Bernstein H,Beveridge M,Cramer S

更新日期：2006-04-01 00:00:00

abstract：:Recent studies have indicated that oxidative stress is involved in the pathogenesis of pre-eclampsia. Oxidative stress damages systemic tissues, and placental damage may result in intrauterine growth retardation and fetal distress. Thus, this study attempted to elucidate the placental localization of thioredoxin and t...

journal_title：Placenta

authors： Ejima K,Nanri H,Toki N,Kashimura M,Ikeda M

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Alloimmunization against human platelet antigens (HPAs) can occur prenatally and induce fetal/neonatal alloimmune thrombocytopenia (FNAIT). The aim of this study was to identify placental histological features associated with platelet alloimmunization and their clinical significance. METHODS:This study exam...

journal_title：Placenta

authors： Dubruc E,Lebreton F,Giannoli C,Rabilloud M,Huissoud C,Devouassoux-Shisheboran M,Allias F

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:The pro-inflammatory mediator and potent vasoconstrictor Endothelin-1 (ET-1) is known to be expressed in the placenta. We have recently demonstrated that very low, non-toxic doses of carbon monoxide (CO), prevented infection-induced preterm birth in mice. However the effect(s) of CO on human gestational ti...

journal_title：Placenta

authors： Olgun NS,Arita Y,Hanna M,Murthy A,Tristan S,Peltier MR,Hanna N

更新日期：2014-06-01 00:00:00

abstract：:Despite the vital and diverse roles of the placenta, remarkably little is known about its actual composition. Moreover, as placentophagy becomes increasingly popular, understanding the nutritional and heavy metal composition of the human placenta has practical implications. Here we evaluated the carbohydrate, sugar, p...

journal_title：Placenta

authors： Chang S,Lodico L,Williams Z

更新日期：2017-12-01 00:00:00

abstract：:Antigenic material previously detected in human placental trophoblastic cells by immunoperoxidase staining using a goat antiserum against the feline RD114 retrovirus structural protein p30 was isolated by immunochromatography from normal syncytiotrophoblast. The antigen was used to immunize mice, and of the monoclonal...

journal_title：Placenta

authors： Wahlström T,Nieminen P,Närvänen A,Suni J,Lehtovirta P,Saksela E,Vaheri A

更新日期：1984-11-01 00:00:00

abstract：:Peroxidase (Donor: H(2)O(2)oxidoreductase EC 1.11.1.7) from human term placentae of non-smokers was purified to homogeneity by a combination of NH(4)Cl extraction, affinity chromatography, (NH(4))(2)SO(4)precipitation, ion-exchange and gel filtration chromatography. The homogeneity of purified human placental peroxida...

journal_title：Placenta

authors： Madhavan ND,Naidu KA

更新日期：2000-07-01 00:00:00

abstract：:The purpose of this study was to examine evidence for the presence of activated leukocytes in the fetal membranes from patients with preterm delivery. Polymorphonuclear leukocytes in fetal membranes from seven patients with preterm delivery (26-32 weeks of gestation) were analysed using transmission electron microscop...

journal_title：Placenta

authors： Matsubara S,Yamada T,Minakami H,Watanabe T,Takizawa T,Sato I

更新日期：1999-03-01 00:00:00

abstract：:During the first trimester of pregnancy the human placenta develops in an hypoxic environment caused by the occlusion of uterine spiral arterioles by extravillous trophoblasts (EVT). This period of low oxygen tension is crucial for successful pregnancy. In low oxygen environments, Hypoxia Inducible Factors (HIF) are t...

journal_title：Placenta

authors： Patel J,Landers K,Mortimer RH,Richard K

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:Miscarriage is the most common placental-related complication of pregnancy. It has been extensively investigated to discover the underlying mechanism(s) by which miscarriage occurs, but in many cases the etiology still remains unclear. The aim of this study was to analyze genome-wide expression profiles of...

journal_title：Placenta

authors： Lyu SW,Song H,Yoon JA,Chin MU,Sung SR,Kim YS,Lee WS,Yoon TK,Cha DH,Shim SH

更新日期：2013-02-01 00:00:00

abstract：INTRODUCTION:Infection accounts for over 40% of preterm premature rupture of the fetal membranes (PPROM), a major cause of preterm birth. Toll-like receptors (TLR) play key roles in pathogen surveillance but their expression and function in amnion mesenchymal cells (AMC) is unclear. The aims of this study were to deter...

journal_title：Placenta

authors： Sato BL,Collier ES,Vermudez SA,Junker AD,Kendal-Wright CE

更新日期：2016-08-01 00:00:00

abstract：:Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated with pregnancy complications such as preeclampsia and gestational diabetes, and offspring long-term metabolic health is impacted as the consequence of altered fetal growth, physiology and often iatrogenic prematurity. The meta...

journal_title：Placenta

authors： Delhaes F,Giza SA,Koreman T,Eastabrook G,McKenzie CA,Bedell S,Regnault TRH,de Vrijer B

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:Placental transport is the main factor affecting the health and development of the fetus. Due to the placenta's geometrical and mathematical complexity, the structure-function relations of placental terminal villi have not been successfully modeled. Hence, a novel modeling approach is proposed. METHODS:Co...

journal_title：Placenta

authors： Plitman Mayo R,Charnock-Jones DS,Burton GJ,Oyen ML

更新日期：2016-07-01 00:00:00

abstract：:Placental Site Trophoblastic Tumor (PSTT) is a rare form of Gestational Trophoblastic Disease (GTD). Approximately 200 cases have been reported in the literature. This disease has unpredictable biological behavior, whereas approximately 10-15% have clinically malignant evolution. We present the case of a 21-year old w...

journal_title：Placenta

authors： Colecchi C,Partemi S,Minelli N,Cascini F,Rossi R,Fulcheri E,Pascali VL,Oliva A

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To evaluate pregnancy outcome and ultrasound diagnosis in patients with histologically-confirmed placental chorioangioma. STUDY DESIGN:Placentas with histological diagnosis of chorioangioma were identified and medical charts were reviewed for findings of ultrasound examinations. Pregnancy outcomes were compa...

journal_title：Placenta

authors： Wou K,Chen MF,Mallozzi A,Brown RN,Shrim A

更新日期：2011-09-01 00:00:00

abstract：:Fetal growth restriction (FGR) is the failure of a fetus to reach its full genetic growth potential. It occurs in up to 8% of pregnancies, and after premature birth is the second leading cause of infant mortality and morbidity. There is no treatment currently available for FGR. Its primary cause, when not attributable...

journal_title：Placenta

authors： Swanson AM,David AL

更新日期：2015-06-01 00:00:00

abstract：:Parathyroid hormone-related protein (PTHrP), the major factor responsible for hypercalcaemia of malignancy, is widely expressed in normal adult and fetal tissues. In this study, the distribution of PTHrP was examined in human term placenta and membranes by immunohistochemistry using antisera to PTHrP 1-34 and 37-67. P...

journal_title：Placenta

authors： Emly JF,Gregory J,Bowden SJ,Ahmed A,Whittle MJ,Rushton DI,Ratcliffe WA

更新日期：1994-09-01 00:00:00

abstract：:The diversity of placental structures in Eutherian mammals is such that drawing generalizations from the definitive forms is problematic. There are always areas of reduced interhaemal distance whether the placenta is epitheliochorial, synepitheliochorial, endotheliochorial or haemochorial. However, the thinning may be...

journal_title：Placenta

authors： Enders AC,Carter AM

更新日期：2004-04-01 00:00:00

abstract：:Decidualization process involves the morphological and functional transformation of endometrial stromal cells into decidual cells. This is a finely regulated process, which involves proliferation and differentiation of stromal cells into decidual cells, which is followed by regression of the decidual tissue, mainly by...

journal_title：Placenta

authors： Fonseca BM,Teixeira NA,Almada M,Taylor AH,Konje JC,Correia-da-Silva G

更新日期：2011-06-01 00:00:00

abstract：:The transcription factor Krüppel-Like Factor 6 (KLF6) has important roles in cell differentiation, angiogenesis, apoptosis, and proliferation. Furthermore, there is evidence that KLF6 is required for proper placental development. While oxygen is a critical mediator of trophoblast differentiation and function, the invo...

journal_title：Placenta

authors： Racca AC,Ridano ME,Bandeira CL,Bevilacqua E,Avvad Portari E,Genti-Raimondi S,Graham CH,Panzetta-Dutari GM

更新日期：2016-09-01 00:00:00

abstract：:Highly purified (>99.99%) primary villous cytotrophoblasts from uncomplicated pregnancies and pregnancies complicated with intrauterine growth restriction (IUGR) alone, IUGR with pre-eclampsia (IUGR-PE) and PE alone were cultured for 5days and the extent of differentiation into syncytiotrophoblasts measured in terms o...

journal_title：Placenta

authors： Newhouse SM,Davidge ST,Winkler-Lowen B,Demianczuk N,Guilbert LJ

更新日期：2007-10-01 00:00:00

abstract：:Maternal fever is common during pregnancy and has for many years been suspected to harm the developing fetus. Whether increased maternal temperature produces exaggerated apoptosis in trophoblast cells remains unclear. Since p53 is a critical regulator of apoptosis we hypothesized that increased temperature in placenta...

journal_title：Placenta

authors： Pérez-Pérez A,Toro AR,Vilarino-Garcia T,Guadix P,Maymó JL,Dueñas JL,Varone CL,Sánchez-Margalet V

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:Gestational diabetes mellitus (GDM) is an increasing harm in pregnancy. Inflammatory processes in the placenta seem to have an influence on pathogenesis besides known factors like maternal BMI. Galectin-13 (gal-13) is an immunoregulatory protein, which is suspected to play a role in development of GDM in t...

journal_title：Placenta

authors： Unverdorben L,Hüttenbrenner R,Knabl J,Jeschke U,Hutter S

更新日期：2015-02-01 00:00:00

abstract：:Cytophotometric measurement of the DNA content of Feulgen-stained nuclei in touch preparations of bovine placentomes (n =5) revealed that 8C nuclei occurred in all, 16C nuclei in two, and 32C nuclei in one specimen. The determination of ploidy level by in situ hybridization with a Y-chromosome specific DNA probe showe...

journal_title：Placenta

authors： Klisch K,Hecht W,Pfarrer C,Schuler G,Hoffmann B,Leiser R

更新日期：1999-07-01 00:00:00

abstract：:Pregnant mothers are exposed to a wide variety of foreign chemicals. This exposure is most commonly due to maternal medication, lifestyle factors, such as smoking, drug abuse, and alcohol consumption, or occupational and environmental sources. Foreign compounds may interfere with placental functions at many levels e.g...

journal_title：Placenta

authors： Myllynen P,Pasanen M,Pelkonen O

更新日期：2005-05-01 00:00:00

abstract：:Placentas and plasma from women with and without Chagas' disease and cultures of human placental villi with Trypanosoma cruzi, neuraminidase, phospholipase A2 and phospholipase C were analyzed in order to verify if the alterations in placental alkaline phosphatase (PLAP) enzyme activity are caused by T. cruzi as obser...

journal_title：Placenta

authors： Lin S,Sartori MJ,Mezzano L,de Fabro SP

更新日期：2005-11-01 00:00:00