Antigen expression by trophoblast populations in the human placenta and their possible immunobiological relevance.

abstract：:Maternal and fetal cellular relationships in the normal human term placental basal plate were investigated by single and double immunohistochemical labelling techniques. Extravillous fetal trophoblast in the basal plate was uniformly reactive with markers of low-molecular-weight cytokeratins. The predominant maternal ...

journal_title：Placenta

authors： Bulmer JN,Smith J,Morrison L,Wells M

更新日期：1988-05-01 00:00:00

abstract：:Pre-eclampsia and placenta accreta have opposite histological features of placentation. This study set out to test the hypotheses that the sex ratios in these two pregnancy complications are opposite and that these conditions are mutually exclusive. A population-based database covering all deliveries in South Australi...

journal_title：Placenta

authors： Khong TY,Staples A,Chan AS,Keane RJ,Wilkinson CS

更新日期：1998-11-01 00:00:00

abstract：:Cytophotometric measurement of the DNA content of Feulgen-stained nuclei in touch preparations of bovine placentomes (n =5) revealed that 8C nuclei occurred in all, 16C nuclei in two, and 32C nuclei in one specimen. The determination of ploidy level by in situ hybridization with a Y-chromosome specific DNA probe showe...

journal_title：Placenta

authors： Klisch K,Hecht W,Pfarrer C,Schuler G,Hoffmann B,Leiser R

更新日期：1999-07-01 00:00:00

abstract：:Preeclampsia (PE) is a serious pregnancy-related syndrome, which is characterized by gestational hypertension and proteinuria. The microRNA-93 (miR-93) is upregulated in the maternal plasma of patients with PE. However, the functional role of miR-93 in PE remains unknown. Here, we identified that miR-93 inhibits troph...

journal_title：Placenta

authors： Pan Q,Niu H,Cheng L,Li X,Zhang Q,Ning Y

更新日期：2017-05-01 00:00:00

abstract：:Mice were inoculated with Theiler's murine encephalomyelitis virus (TMEV) on gestational days 1-3 (pre-implantation) or days 4-5 (peri- or post-implantation) or with control cell lysate (days 1-5). Dams were subsequently sacrificed between days 11-14 of gestation, and placentae and fetuses were harvested. Few placenta...

journal_title：Placenta

authors： Abzug MJ,Tyson RW

更新日期：2000-05-01 00:00:00

abstract：:In the present study, we characterized the expression of lymphocyte antigen 6, locus E (Ly6e) in mouse placental trophoblast. We identified Ly6e mRNA expression in trophoblast stem (TS) cells by a gene expression screen. In vivo, Ly6e was first detectable by mRNA in situ hybridization in the chorion beginning at E8.5 ...

journal_title：Placenta

authors： Hughes M,Natale BV,Simmons DG,Natale DR

更新日期：2013-09-01 00:00:00

abstract：:Amniotic fluid exerts a protective function and is an essential component for foetal development and maturation during pregnancy. However, little is known about the exact physiological functions of foetal fluids in this process as well as their biochemical composition in cats. In the present study, the biochemical com...

journal_title：Placenta

authors： Fresno L,Rodriguez-Gil JE,Rigau T,Pastor J,Rivera del Alamo MM

更新日期：2012-06-01 00:00:00

abstract：:Human parvovirus B19 (B19) infection during pregnancy can result in horizontal transmission of the virus and congenital infection. The main targets for B19 replication are the erythroid precursor cell of the colony and burst forming units. The cellular receptor necessary for B19 infectivity is globoside. Other non-ery...

journal_title：Placenta

authors： Jordan JA,Butchko AR

更新日期：2002-08-01 00:00:00

abstract：INTRODUCTION:Little is known about the interaction between human placental multipotent mesenchymal stromal cell (hPMSC) and trophoblast. We hypothesize that hPMSCs produce hepatocyte growth factor (HGF) which may interact with trophoblasts and regulate their migration during placentation. METHODS:hPMSCs were isolated ...

journal_title：Placenta

authors： Chen CP,Huang JP,Chu TY,Aplin JD,Chen CY,Wu YH

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:Knockout mouse model has shown a relationship between Slit2/Robo1 signalling and altered fertility. Altered expression by endometrial epithelium and trophoblast and is associated with the pathogenesis of pregnancy complications but few studies have investigated the expression of decidual Slit2 in miscarria...

journal_title：Placenta

authors： Chen J,Liu J,Gao S,Qiu Y,Wang Y,Zhang Y,Gao L,Qi G,Wu Y,Lash GE,Li P

更新日期：2020-10-09 00:00:00

abstract：INTRODUCTION:Preeclampsia is one of the main causes of morbidity and mortality in pregnant women and mothers. Numerous studies showed that microRNAs (miRNAs) played important roles in the occurrence and development of preeclampsia. However, the regulation of microRNA-142-3p (miR-142-3p) in preeclampsia has not been cla...

journal_title：Placenta

authors： Mao Y,Hou B,Shan L,Sun X,Wang L

更新日期：2021-01-06 00:00:00

abstract：:The ability to directly monitor the status of the placenta throughout pregnancy would be a major advance in both general and personalized obstetric care, allowing treatments to be tailored to the dynamic changes that can occur in gestation. Syncytiotrophoblast extracellular vesicles (STBEV) are membrane bound vesicles...

journal_title：Placenta

authors： Tannetta D,Collett G,Vatish M,Redman C,Sargent I

更新日期：2017-04-01 00:00:00

abstract：INTRODUCTION:The interaction between trophoblast cells and maternal uterine endothelium is important for placental vascular modelling. Nitric oxide (NO) is a potent vasorelaxant that regulates systemic blood pressure and is reduced in preeclampsia. NO may affect placental cell interaction. OBJECTIVES:This study was to...

journal_title：Placenta

authors： Xu B,Charlton F,Makris A,Hennessy A

更新日期：2014-06-01 00:00:00

abstract：:The transcription factor Krüppel-Like Factor 6 (KLF6) has important roles in cell differentiation, angiogenesis, apoptosis, and proliferation. Furthermore, there is evidence that KLF6 is required for proper placental development. While oxygen is a critical mediator of trophoblast differentiation and function, the invo...

journal_title：Placenta

authors： Racca AC,Ridano ME,Bandeira CL,Bevilacqua E,Avvad Portari E,Genti-Raimondi S,Graham CH,Panzetta-Dutari GM

更新日期：2016-09-01 00:00:00

abstract：:The effects of 8-epi-prostaglandin F(2alpha)(8-epi-PGF(2alpha)) and the thromboxane A(2)-mimetic U46619 were examined on isolated human fetal placental arteries obtained from normal pregnancies and from those complicated by pre-eclampsia. The effects of these agents were examined on both conduit and resistance arterie...

journal_title：Placenta

authors： Kwek K,Read MA,Khong TY,Bisits AT,Walters WA

更新日期：2001-07-01 00:00:00

abstract：:Our objective was to evaluate whether antiphospholipid antibody-containing sera could play a regulatory role in signal transduction induced by gonadotrophin releasing hormone (GnRH) when incubated with normal human trophoblast cells. To test this hypothesis we established an in vitro placental culture system in which ...

journal_title：Placenta

authors： Di Simone N,De Carolis S,Lanzone A,Ronsisvalle E,Giannice R,Caruso A

更新日期：1995-01-01 00:00:00

abstract：:Hyperplastic placentas have been reported in several experimental mouse models, including animals produced by somatic cell nuclear transfer, by inter(sub)species hybridization, and by somatic cytoplasm introduction to oocytes followed by intracytoplasmic sperm injection. Of great interest are the gross and histologica...

journal_title：Placenta

authors： Wakisaka N,Inoue K,Ogonuki N,Miki H,Sekita Y,Hanaki K,Akatsuka A,Kaneko-Ishino T,Ishino F,Ogura A

更新日期：2008-08-01 00:00:00

abstract：:Oestrogen and progesterone receptors have been implicated in human placental steroidogenesis, but studies developed to measure their concentration in this tissue at term yielded discrepant results. Potential inaccuracy of the binding assays, the technique used in previous studies, might influence the discrepancy. In t...

journal_title：Placenta

authors： Rivera J,Cano A

更新日期：1989-11-01 00:00:00

abstract：:The aim of this work was to characterize the uptake of 1-methyl-4-phenylpyridinium (MPP(+)) in the JAR human choriocarcinoma cell line. As JAR cells, as well as the placenta, express the neuronal serotonin transporter (SERT), a comparison between the uptake of (3)H-MPP(+) and (3)H-serotonin ((3)H-5HT) was made. Specif...

journal_title：Placenta

authors： Martel F,Keating E

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:Alcohol consumption is a common social practice among women of childbearing age. With 50% of pregnancies being unplanned, many embryos are exposed to alcohol prior to pregnancy recognition and formation of the placenta. The effects of periconceptional (PC) alcohol exposure on the placenta are unknown. MET...

journal_title：Placenta

authors： Gårdebjer EM,Cuffe JS,Pantaleon M,Wlodek ME,Moritz KM

更新日期：2014-01-01 00:00:00

abstract：:Previous studies have shown that human and mouse placentas have hematopoietic potential during mid-gestation. In this investigation, we used histological and immunohistological approaches to visualize hematopoietic cells in mouse placenta between 9.5 and 12.5 days of gestation (gd), identifying their topography and ni...

journal_title：Placenta

authors： Azevedo Portilho N,Tavares Guedes P,Croy BA,Pelajo-Machado M

更新日期：2016-11-01 00:00:00

abstract：:The placenta receives two arterial blood supplies, i.e. one maternal and one fetal. It has been suggested that placental infarction should occur only if both blood supplies are compromised (Wigglesworth, 1984). This hypothesis has not been tested. Haemosiderosis of the trophoblast basement membrane (TBMH) has recently...

journal_title：Placenta

authors： McDermott M,Gillan JE

更新日期：1995-03-01 00:00:00

abstract：:Growth characteristics and the expression of trophoblast-associated markers by six cell lines generated from midgestation chorioallantoic placentas of outbred (Holtzman) and inbred (Lewis, PVG.RT Ir8) rats were evaluated. The cells comprising all cell lines were epithelioid (contained cytokeratin-type intermediate fil...

journal_title：Placenta

authors： Hunt JS,Deb S,Faria TN,Wheaton D,Soares MJ

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Scant data on placental lymphatic vessels have pointed to the absence of lymphatic circulation. A recent study on mesenchymal dysplasia (MD), however, has identified pathologic lymphangiogenesis using the D2-40 lymphatic marker. These conflicting data have prompted us to investigate whether lymphatic vessels...

journal_title：Placenta

authors： Castro E,Tony Parks W,Galambos C

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:The ratio of birthweight to placental weight (BW:PW) is often used as a measure of placental efficiency in humans and animals. However, ratios have properties that are known to lead to spurious results. An alternative approach is the use of residuals from regression, which reflect whether birthweight is hi...

journal_title：Placenta

authors： Christians JK,Grynspan D,Greenwood SL,Dilworth MR

更新日期：2018-08-01 00:00:00

abstract：INTRODUCTION:Human decidual stromal cells (DSCs) play a key role in maternal-fetal interactions. Precursors of DSCs (preDSCs) localize around vessels in both the endometrium and decidua. Previous studies suggested a relationship between preDSCs and pericytes because these cells share a perivascular location, alpha smoo...

journal_title：Placenta

authors： Muñoz-Fernández R,de la Mata C,Prados A,Perea A,Ruiz-Magaña MJ,Llorca T,Fernández-Rubio P,Blanco O,Abadía-Molina AC,Olivares EG

更新日期：2018-01-01 00:00:00

abstract：:In human placenta aminopeptidase A (APA), a principal enzyme that converts angiotensin II to angiotensin III, seems to be involved in angiotensin II metabolism during pregnancy. In this study, we investigated the possible effects of progesterone and estrogen on APA mRNA and protein levels in choriocarcinoma cells as a...

journal_title：Placenta

authors： Katsumata Y,Nomura S,Ino K,Iwanaga K,Kurosawa N,Ito T,Okada M,Tsujimoto M,Kikkawa F,Mizutani S

更新日期：2001-11-01 00:00:00

abstract：:The gestational age and litter size in the guinea pig can be accurately assessed by taking an x-ray of the animal. From a measurement of the fetal head length on the x-ray plate a fetal weight can be calculated using previously accumulated data, included here. The gestational age can be assessed from this weight to wi...

journal_title：Placenta

authors： Thomas CR,Lowy C

更新日期：1982-01-01 00:00:00

abstract：INTRODUCTION:Chronic abruption oligohydramnios sequence (CAOS) is histologically characterized by diffuse chorioamniotic hemosiderosis (DCH). However, the criteria for the histological evaluation of the extent of CAOS-related hemosiderin deposition (HD) of the membranes and the difference in HD between the chorionic pl...

journal_title：Placenta

authors： Ishida A,Minamiguchi S,Yamada Y,Nakagawa R,Chigusa Y,Kondoh E,Mandai M,Haga H

更新日期：2021-01-20 00:00:00

abstract：INTRODUCTION:The purpose of this study was to evaluate whether currently available fetal Magnetic Resonance Imaging (MRI/MR) techniques are sufficient for the assessment of placental pathologies. We hypothesized that placental pathologies as detected and evaluated by MRI, would correlate with histological findings. PA...

journal_title：Placenta

authors： Linduska N,Dekan S,Messerschmidt A,Kasprian G,Brugger PC,Chalubinski K,Weber M,Prayer D

更新日期：2009-06-01 00:00:00