The assessment of gestational age and litter size in the guinea pig using a radiographic method.

abstract：:Angiotensinogen is the substrate for the enzyme renin. In addition to the well-characterized low molecular weight forms of angiotensinogen, a high molecular weight form (HMrA) comprises about 15 per cent of the total angiotensinogen in plasma of pregnant women. In the current study the different forms of angiotensinog...

journal_title：Placenta

authors： Lenz T,Sealey JE,Tewksbury DA

更新日期：1993-11-01 00:00:00

abstract：:The purpose of this study was to examine evidence for the presence of activated leukocytes in the fetal membranes from patients with preterm delivery. Polymorphonuclear leukocytes in fetal membranes from seven patients with preterm delivery (26-32 weeks of gestation) were analysed using transmission electron microscop...

journal_title：Placenta

authors： Matsubara S,Yamada T,Minakami H,Watanabe T,Takizawa T,Sato I

更新日期：1999-03-01 00:00:00

abstract：:During pregnancy, changes in oxygen tension are essential for proper embryonic and placental development. Little is known about the mechanisms underlying mammalian cellular adaptations to changes in oxygen tension. Currently, we have explored putative mechanisms by which human trophoblast cells may sense oxygen. In or...

journal_title：Placenta

authors： De Marco CS,Caniggia I

更新日期：2002-04-01 00:00:00

abstract：INTRODUCTION:Notch signalling has been shown to control cytotrophoblast (CTB) proliferation, differentiation and motility suggesting that the conserved signalling pathway could be critical for human placental development. Since individual Notch receptors have not been elucidated, we herein investigated expression patte...

journal_title：Placenta

authors： Plessl K,Haider S,Fiala C,Pollheimer J,Knöfler M

更新日期：2015-04-01 00:00:00

abstract：:Hofbauer cells have been identified by morphological criteria in human placentae and are considered to be mononuclear phagocytes. An increasing recognition of the morphological heterogeneity of mononuclear phagocytes and of the considerable difficulty in their recognition in histological sections has suggested that th...

journal_title：Placenta

authors： Wood GW

更新日期：1980-04-01 00:00:00

abstract：:The visceral yolk sac (VYS) is responsible for a major part of the amino acid nutrition of the early post-implantation rat embryo and possibly also at the fetal stage of gestation. The mechanism involves endocytic uptake of proteins by the tissue's epithelial cells followed by intralysosomal digestion to amino acids. ...

journal_title：Placenta

authors： Pratten MK,Lloyd JB

更新日期：1997-09-01 00:00:00

abstract：:Anandamide (AEA) and 2-arachidonoylglycerol (2-AG) were the first endocannabinoids to be characterized, that bind two G protein-coupled receptors, CB1 and CB2. AEA synthesized by multiple pathways, including NAPE-specific phospholipase D (NAPE-PLD) and degraded by the fatty acid amide hydrolase (FAAH). AEA levels are ...

journal_title：Placenta

authors： Trabucco E,Acone G,Marenna A,Pierantoni R,Cacciola G,Chioccarelli T,Mackie K,Fasano S,Colacurci N,Meccariello R,Cobellis G,Cobellis L

更新日期：2009-06-01 00:00:00

abstract：:Maternal and fetal cellular relationships in the normal human term placental basal plate were investigated by single and double immunohistochemical labelling techniques. Extravillous fetal trophoblast in the basal plate was uniformly reactive with markers of low-molecular-weight cytokeratins. The predominant maternal ...

journal_title：Placenta

authors： Bulmer JN,Smith J,Morrison L,Wells M

更新日期：1988-05-01 00:00:00

abstract：INTRODUCTION:Preeclampsia is a severe pregnancy complication mostly due to inadequate vascular dilation and remodeling of spiral arteries. VEGF, the major factor for angiogenesis, is necessary for modulating angiogenic processes in the placenta. Hence reduction of VEGF in gestational hypertension may also lead to hypop...

journal_title：Placenta

authors： Guo X,Feng L,Jia J,Chen R,Yu J

更新日期：2016-10-01 00:00:00

abstract：:The mechanism of iron release from the placenta into the fetal circulation is not well understood. Ceruloplasmin, a plasma ferroxidase, has been implicated in iron efflux from a variety of cell types. The hypothesis is that circulating ceruloplasmin facilitates iron efflux by oxidizing the released Fe(II) to Fe(III) f...

journal_title：Placenta

authors： Danzeisen R,Ponnambalam S,Lea RG,Page K,Gambling L,McArdle HJ

更新日期：2000-11-01 00:00:00

abstract：:Placental pathology is a valuable link explaining how underlying pregnancy risk factors result in adverse pregnancy outcome. This potentially useful information is currently underutilized due to a general lack of rigor in placental diagnosis. This lack of rigor is in large part due to a failure to appreciate the impor...

journal_title：Placenta

authors： Redline RW,Heller D,Keating S,Kingdom J

更新日期：2005-04-01 00:00:00

abstract：:The processes of proliferation, migration, and invasion of extravillous trophoblasts are critical for placental implantation and early development, and directly influence pregnancy outcome. Dysregulation of these processes has been associated with placental dysfunction, implicated in clinical conditions such as preecl...

journal_title：Placenta

authors： Xie L,Sadovsky Y

更新日期：2016-12-01 00:00:00

abstract：:In order to assess the characteristics of its stromal cells and the distribution of extracellular matrix proteins, we investigated, immunohistochemically and ultrastructurally, term, first and second trimester human umbilical cords. A differential distribution pattern of the various cytoskeletal proteins of stromal ce...

journal_title：Placenta

authors： Nanaev AK,Kohnen G,Milovanov AP,Domogatsky SP,Kaufmann P

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To study the association between velamentous cord insertion (VCI) and different outcomes in monochorionic twins with and without twin-twin transfusion syndrome (TTTS). METHODS:We recorded the cord insertion type in all consecutive monochorionic placentas examined in two tertiary medical centers. The associat...

journal_title：Placenta

authors： Costa-Castro T,De Villiers S,Montenegro N,Severo M,Oepkes D,Matias A,Lopriore E

更新日期：2013-11-01 00:00:00

abstract：:Intrauterine growth and development can impact upon the long-term health of an individual. The fetus is dependent upon the placenta for its supply of nutrients and oxygen from the mother. In turn, the functional capacity of the placenta to supply that demand is under the control of the fetal and maternal genomes. Rece...

journal_title：Placenta

authors： Angiolini E,Fowden A,Coan P,Sandovici I,Smith P,Dean W,Burton G,Tycko B,Reik W,Sibley C,Constância M

更新日期：2006-04-01 00:00:00

abstract：:During pregnancy, leptin concentrations in the maternal circulation are elevated in both humans and rodents but decrease to pre-pregnancy levels at birth, suggesting a role for leptin in the maintenance of pregnancy. Synthesis of leptin by the human placenta is established but whether the murine placenta synthesizes l...

journal_title：Placenta

authors： Malik NM,Carter ND,Wilson CA,Scaramuzzi RJ,Stock MJ,Murray JF

更新日期：2005-01-01 00:00:00

abstract：:A rapid method to determine quality for placental proteomic studies is required due to varying lengths of time between delivery and sampling in routine protocols. We developed a rapid 10 min LC-MS based scanning method to profile free peptides liberated from natural proteolytic degradation. The assay was applied to pl...

journal_title：Placenta

authors： Heywood WE,Pryce J,Virasami A,Preece RL,Dezateux C,Mills K,Sebire NJ

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:In the placenta, the (pro)renin receptor (ATP6AP2) is localised to the syncytiotrophoblast. ATP6AP2 can activate the placental renin-angiotensin system (RAS), producing Angiotensin II (Ang II) which, acting via the angiotensin II type 1 receptor (AGTR1), is important for placental development and function....

journal_title：Placenta

authors： Morosin SK,Delforce SJ,Lumbers ER,Pringle KG

更新日期：2020-08-01 00:00:00

abstract：:The placenta receives two arterial blood supplies, i.e. one maternal and one fetal. It has been suggested that placental infarction should occur only if both blood supplies are compromised (Wigglesworth, 1984). This hypothesis has not been tested. Haemosiderosis of the trophoblast basement membrane (TBMH) has recently...

journal_title：Placenta

authors： McDermott M,Gillan JE

更新日期：1995-03-01 00:00:00

abstract：:Neuropeptides play an important role in the regional regulation of blood flow and hormone secretion. Few studies report the presence of peptides in the human placenta. Our experiment evaluates neuropeptides in the human placenta using immunocytochemical techniques. Representative tissue sections from full-term placent...

journal_title：Placenta

authors： Graf AH,Hütter W,Hacker GW,Steiner H,Anderson V,Staudach A,Dietze O

更新日期：1996-09-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to explore serum levels of differentially abundant proteins between women with hypertensive disorders of pregnancy (HDP) and women with normal-term pregnancy, and to explore the contribution of SH3BGRL3 to the pathogenesis of HDP. METHODS:At 6-20 weeks gestation 48 pregnant...

journal_title：Placenta

authors： Jiang M,Lash GE,Zeng S,Liu F,Han M,Long Y,Cai M,Hou H,Ning F,Hu Y,Yang H

更新日期：2020-11-14 00:00:00

abstract：:Intrauterine inflammation contributes to neonatal infection-related morbidity. A new histological framework of placental inflammation has recently been proposed; however, the association between this method and clinical findings has not been defined. To assess the clinical relevance of this system, we studied placenta...

journal_title：Placenta

authors： Yamada N,Sato Y,Moriguchi-Goto S,Yamashita A,Kodama Y,Sameshima H,Asada Y

更新日期：2015-12-01 00:00:00

abstract：:Cytosol preparations of human term placenta in Tris-HCl buffer containing dithiothreitol were incubated with [3H]dexamethasone at 4 degrees C. Under these conditions the specific binding of [3H]dexamethasone was low when compared with cytosol preparations of sheep fetal lung or ovine placenta. The inclusion of sodium ...

journal_title：Placenta

authors： López Bernal A,Anderson AB,Turnbull AC

更新日期：1984-03-01 00:00:00

abstract：:Highly purified (>99.99%) primary villous cytotrophoblasts from uncomplicated pregnancies and pregnancies complicated with intrauterine growth restriction (IUGR) alone, IUGR with pre-eclampsia (IUGR-PE) and PE alone were cultured for 5days and the extent of differentiation into syncytiotrophoblasts measured in terms o...

journal_title：Placenta

authors： Newhouse SM,Davidge ST,Winkler-Lowen B,Demianczuk N,Guilbert LJ

更新日期：2007-10-01 00:00:00

abstract：:11β-Hydroxysteroid dehydrogenase 1 and 2 (11β-HSD1 and 11β-HSD2) are involved in the complex mechanism of human parturition. The present study examined mRNA expression and activity of membrane 11β-HSD1 and placental 11β-HSD2 in postdate pregnancies according to response of labor induction. In comparison to postdate wo...

journal_title：Placenta

authors： Novembri R,Voltolini C,Torricelli M,Severi FM,Marcolongo P,Benedetti A,Challis JR,Petraglia F

更新日期：2013-11-01 00:00:00

abstract：:TRH immunological and biological activity was characterized in rat placental extracts. Placentae were extracted sequentially with 2 N acetic acid and glacial acetic acid. The lyophilized residues were further extracted with 90 per cent methanol, and the extracts were then dried, and reextracted with distilled water. W...

journal_title：Placenta

authors： Shambaugh GE 3rd,Kubek M,Wilber JF

更新日期：1983-10-01 00:00:00

abstract：:The human placental syncytiotrophoblast is derived from differentiating cytotrophoblasts and is in contact with maternal blood. This endothelial function positions the trophoblast to regulate maternal-fetal exchange and to influence circulatory dynamics through paracrine interactions in the placenta. Two isoforms of n...

journal_title：Placenta

authors： Lyall F,Jablonka-Shariff A,Johnson RD,Olson LM,Nelson DM

更新日期：1998-05-01 00:00:00

abstract：:During the first trimester of pregnancy the human placenta develops in an hypoxic environment caused by the occlusion of uterine spiral arterioles by extravillous trophoblasts (EVT). This period of low oxygen tension is crucial for successful pregnancy. In low oxygen environments, Hypoxia Inducible Factors (HIF) are t...

journal_title：Placenta

authors： Patel J,Landers K,Mortimer RH,Richard K

更新日期：2010-11-01 00:00:00

abstract：:Alphafetoprotein (AFP) is detectable in maternal serum from around six weeks of gestation and is synthesised by the yolk sac and the fetal liver. The role of the placenta in the transport and possible synthesis of AFP is uncertain. The aim of this study was to investigate placental expression of AFP and the AFP recept...

journal_title：Placenta

authors： Newby D,Dalgliesh G,Lyall F,Aitken DA

更新日期：2005-02-01 00:00:00

abstract：:Maternal feed allowance during pregnancy can affect the development of the ovine placenta and fetus. The impact of variations in feed allowance prior to as well as throughout pregnancy has received less attention. Ewes were offered 0.6 (R), 1.2 (C) or 1.8 (AL) maintenance requirements from 89 days before conception un...

journal_title：Placenta

authors： Quigley SP,Kleemann DO,Walker SK,Speck PA,Rudiger SR,Nattrass GS,DeBlasio MJ,Owens JA

更新日期：2008-06-01 00:00:00