Abstract:
:The recognition of recurrent aberrant regions in cancer is important to the discovery of candidate cancer related genes. Here we first constructed a genome-wide gene expression map of squamous lung carcinoma from the Stanford Microarray Database. High-resolution detection of aberrant chromosomal regions was performed by using moving-median method. 84% (27 of 32) of our results were consistent with the previous studies of comparative genomic hybridization or loss of heterozygosity. One overrepresented region in Xq28 was newly discovered to be related to squamous cell lung carcinoma. These observations could be of great interest for further studies.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Zhang XY,Hu Y,Cui YP,Miao XP,Tian F,Xia YJ,Wu YQ,Liu Xdoi
10.1016/j.febslet.2006.04.043subject
Has Abstractpub_date
2006-05-15 00:00:00pages
2774-8issue
11eissn
0014-5793issn
1873-3468pii
S0014-5793(06)00477-7journal_volume
580pub_type
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