Combined effects of blood and temperature shift on Borrelia burgdorferi gene expression as determined by whole genome DNA array.

abstract：:Fifty Borellia burgdorferi strains isolated from humans and ticks in Europe and the United States were analyzed by multilocus enzyme electrophoresis. Eleven genetic loci were characterized on the basis of the electrophoretic mobilities of their products. Ten loci were polymorphic. The average number of alleles per loc...

journal_title：Infection and immunity

authors： Boerlin P,Peter O,Bretz AG,Postic D,Baranton G,Piffaretti JC

更新日期：1992-04-01 00:00:00

abstract：:We have cloned chromosomal genes mediating the aerobactin iron transport system from the enteroinvasive strain Escherichia coli 978-77. The physical map of the region spanning the siderophore biosynthesis genes and the upstream portion of the receptor gene in strain 978-77-derived clones was identical to the correspon...

journal_title：Infection and immunity

authors： Marolda CL,Valvano MA,Crosa JH

更新日期：1991-01-01 00:00:00

abstract：:The production of type 1 fimbriae in Salmonella enterica serovar Typhimurium is controlled, in part, by three proteins, FimZ, FimY, and FimW. Amino acid sequence analysis indicates that FimZ belongs to the family of bacterial response regulators of two-component systems. In these studies, we have demonstrated that int...

journal_title：Infection and immunity

authors： Zeiner SA,Dwyer BE,Clegg S

更新日期：2013-12-01 00:00:00

abstract：:Virulent Treponema pallidum organisms, extracted from infected rabbit testes, were subjected to velocity sedimentation in discontinuous gradients of Hypaque, a high density, low viscosity material. After centrifugation of extracts at 20 C for 45 min at 100,000 x g, treponemes separated into two distinct bands based up...

journal_title：Infection and immunity

authors： Baseman JB,Nichols JC,Rumpp JW,Hayes NS

更新日期：1974-11-01 00:00:00

abstract：:Borrelia burgdorferi, the Lyme disease pathogen, dramatically alters its protein profile when it is transmitted between ticks and mammals. Several differentially expressed proteins have been shown to be critical for the enzootic cycle of B. burgdorferi. In this study, we demonstrated that expression of the surface lip...

journal_title：Infection and immunity

authors： Xu H,He M,He JJ,Yang XF

更新日期：2010-07-01 00:00:00

abstract：:To assess the relationship between the within-host diversity of malaria infections and the susceptibility of the host to subsequent infection, we genotyped 60 children's successive infections from birth through 3 years of life. MSP-1 Block2 genotypes were used to estimate the complexity of infection (COI). Malaria tra...

journal_title：Infection and immunity

authors： Branch OH,Takala S,Kariuki S,Nahlen BL,Kolczak M,Hawley W,Lal AA

更新日期：2001-12-01 00:00:00

abstract：:Peru-15 is a live attenuated oral vaccine derived from a Vibrio cholerae O1 El Tor Inaba strain by a series of deletions and modifications, including deletion of the entire CT genetic element. Peru-15 is also a stable, motility-defective strain and is unable to recombine with homologous DNA. We wished to determine whe...

journal_title：Infection and immunity

authors： Cohen MB,Giannella RA,Bean J,Taylor DN,Parker S,Hoeper A,Wowk S,Hawkins J,Kochi SK,Schiff G,Killeen KP

更新日期：2002-04-01 00:00:00

abstract：:The bactericidal activity of guinea pig and human polymorphonuclear leukocytes (PMNs) against a smooth-intermediate strain (45/0) and a rough strain (45/20) of Brucella abortus has been examined. After incubation for 120 min, guinea pig PMNs incubated with either the smooth strain 45/0 or the rough strain 45/20 exhibi...

journal_title：Infection and immunity

authors： Kreutzer DL,Dreyfus LA,Robertson DC

更新日期：1979-03-01 00:00:00

abstract：:An enterotoxin produced by Bacteroides fragilis was purified to homogeneity and characterized as to its biological activity and basic molecular properties. Toxin preparations were prepared by growing B. fragilis VPI 13784 in brain heart infusion broth to early stationary phase, immediately precipitating the culture su...

journal_title：Infection and immunity

authors： Van Tassell RL,Lyerly DM,Wilkins TD

更新日期：1992-04-01 00:00:00

abstract：:Urease from ureaplasmas was purified by immunoaffinity chromatography, and the N-terminal amino acid sequence was determined for two of the three subunits. These sequences were used to design primers for a polymerase chain reaction (PCR) that amplified most of the gene coding for one of the subunits. By using a novel ...

journal_title：Infection and immunity

authors： Willoughby JJ,Russell WC,Thirkell D,Burdon MG

更新日期：1991-07-01 00:00:00

abstract：:Otitis media developed in 67% of chinchillas inoculated intranasally with type 7 Streptococcus pneumoniae and influenza A virus. Only 4% of chinchillas inoculated with influenza alone and 21% of chinchillas inoculated with S. pneumoniae alone developed otitis media. Among the chinchillas that developed otitis media af...

journal_title：Infection and immunity

authors： Giebink GS,Berzins IK,Marker SC,Schiffman G

更新日期：1980-11-01 00:00:00

abstract：:In a cross-sectional survey of 187 Gambian children and adults, we have analyzed prevalence, fine specificity, and 19-kilodalton merozoite surface protein 1 (MSP-1(19))-specific erythrocyte invasion inhibitory activity of antibodies to MSP-1(19) but find no significant association between any of these parameters and p...

journal_title：Infection and immunity

authors： Corran PH,O'Donnell RA,Todd J,Uthaipibull C,Holder AA,Crabb BS,Riley EM

更新日期：2004-10-01 00:00:00

abstract：:Live attenuated bacteria hold great promise as multivalent mucosal vaccines against a variety of pathogens. A major challenge of this approach has been the successful delivery of sufficient amounts of vaccine antigens to adequately prime the immune system without overattenuating the live vaccine. Here we used a live a...

journal_title：Infection and immunity

authors： Galen JE,Wang JY,Carrasco JA,Lloyd SA,Mellado-Sanchez G,Diaz-McNair J,Franco O,Buskirk AD,Nataro JP,Pasetti MF

更新日期：2015-01-01 00:00:00

abstract：:Addition of a monoclonal antibody which binds the Cryptococcus neoformans capsule to suspensions of human monocytes, T lymphocytes, and cryptococcal cells (i) enhances interleukin-1beta (IL-1beta), tumor necrosis factor alpha, and IL-2 production; (ii) reduces IL-10 secretion; and (iii) promotes T-cell proliferation. ...

journal_title：Infection and immunity

authors： Vecchiarelli A,Retini C,Monari C,Casadevall A

更新日期：1998-03-01 00:00:00

abstract：:A DNA microarray containing fragments of 137 Borrelia burgdorferi B31 putative lipoprotein genes was used to examine Lyme disease spirochetes. DNA from B. burgdorferi sensu stricto B31, 297, and N40; Borrelia garinii IP90; and Borrelia afzelii P/Gau was fluorescently labeled and hybridized to the microarray, demonstra...

journal_title：Infection and immunity

authors： Liang FT,Nelson FK,Fikrig E

更新日期：2002-06-01 00:00:00

abstract：:A common concern with many autoimmune diseases of unknown etiology is the extent to which tissue T-lymphocyte infiltrates, versus a nonspecific infiltrate, reflect a response to the causative agent. Lyme arthritis can histologically resemble rheumatoid synovitis, particularly the prominent infiltration by T lymphocyte...

journal_title：Infection and immunity

authors： Roessner K,Trivedi H,Gaur L,Howard D,Aversa J,Cooper SM,Sigal LH,Budd RC

更新日期：1998-03-01 00:00:00

abstract：:Binding of Escherichia coli strain 431 heat-stable enterotoxin (STa) and activation of intestinal particulate guanylate cyclase by E. coli STa were studied with rat intestinal epithelial cells and brush border membranes (BBMs). The rates of guanylate cyclase stimulation by 431 STa in cells and BBMs were rapid, with ma...

journal_title：Infection and immunity

authors： Dreyfus LA,Robertson DC

更新日期：1984-11-01 00:00:00

abstract：:A cytotoxigenic Clostridium difficile strain that fails to produce toxin A but causes hemorrhage and bloody fluid accumulation in ligated ileal loops of rabbits and hemorrhage and diarrhea in hamsters is described. The lack of reaction of DNA from this strain in hybridization studies with a toxin A gene-specific 4.5-k...

journal_title：Infection and immunity

authors： Borriello SP,Wren BW,Hyde S,Seddon SV,Sibbons P,Krishna MM,Tabaqchali S,Manek S,Price AB

更新日期：1992-10-01 00:00:00

abstract：:Salmonella pathogenicity island 12 (SPI-12) of Salmonella enterica serovar Typhimurium is a 15-kb region that encompasses genes STM2230 to STM2245 and encodes a remnant phage known to contribute to bacterial virulence. In mouse infection experiments and replication assays in macrophages, we demonstrated a role for fou...

journal_title：Infection and immunity

authors： Tomljenovic-Berube AM,Henriksbo B,Porwollik S,Cooper CA,Tuinema BR,McClelland M,Coombes BK

更新日期：2013-07-01 00:00:00

abstract：:In vivo administration of Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) to mice induced apoptosis before a specific immune response. Apoptosis was associated with the expression of immunoglobulin and Ia on B cells and of CD5 and several markers on T cells. Apoptosis peaked in the spleen and lymph nodes on day 2...

journal_title：Infection and immunity

authors： Isogai E,Isogal H,Kimura K,Fujii N,Takagi S,Hirose K,Hayashi M

更新日期：1996-04-01 00:00:00

abstract：:Streptococcus suis serotype 2 is an encapsulated bacterium and one of the most important bacterial pathogens in the porcine industry. Despite decades of research for an efficient vaccine, none is currently available. Based on the success achieved with other encapsulated pathogens, a glycoconjugate vaccine strategy was...

journal_title：Infection and immunity

authors： Goyette-Desjardins G,Calzas C,Shiao TC,Neubauer A,Kempker J,Roy R,Gottschalk M,Segura M

更新日期：2016-06-23 00:00:00

abstract：:The biochemical properties of polymorphonuclear neutrophils from blood and peritoneal exudates of rabbits were compared. All enzymes measured showed almost identical activities in both types of cells, except for alkaline phosphodiesterase, the activity of which was seven times higher in peritoneal neutrophils. During ...

journal_title：Infection and immunity

authors： Takamori K,Yamashita T

更新日期：1980-08-01 00:00:00

abstract：:Bovine mastitis continues to be the most detrimental factor for profitable dairying. Recent research conducted within our laboratory has identified a genetic marker in the CXCR2 gene associated with mastitis susceptibility. The objective of the present study was to evaluate the migratory ability of neutrophils from co...

journal_title：Infection and immunity

authors： Rambeaud M,Pighetti GM

更新日期：2005-08-01 00:00:00

abstract：:Chlorphenesin (3-p-chlorophenoxy-1,2-propanediol), when injected intravenously together with either of two common bacterial antigens, inhibits the antibody response of the rabbit. The antigens studied are those common to Enterobacteriaceae and to gram-positive bacteria. The immunosuppression is contingent upon incubat...

journal_title：Infection and immunity

authors： Whang HY,Neter E

更新日期：1970-07-01 00:00:00

abstract：:Investigating the innate immune response mediators released in milk has manifold implications, spanning from elucidation of the role played by mammary epithelial cells (MECs) in fighting microbial infections to the discovery of novel diagnostic markers for monitoring udder health in dairy animals. Here, we investigate...

journal_title：Infection and immunity

authors： Addis MF,Pisanu S,Marogna G,Cubeddu T,Pagnozzi D,Cacciotto C,Campesi F,Schianchi G,Rocca S,Uzzau S

更新日期：2013-09-01 00:00:00

abstract：:In this study, we investigated the cell wall-anchored fibronectin-binding proteins SpsD and SpsL from the canine commensal and pathogen Staphylococcus pseudintermedius for their role in promoting bacterial invasion of canine progenitor epidermal keratinocytes (CPEK). Invasion was examined by the gentamicin protection ...

journal_title：Infection and immunity

authors： Pietrocola G,Gianotti V,Richards A,Nobile G,Geoghegan JA,Rindi S,Monk IR,Bordt AS,Foster TJ,Fitzgerald JR,Speziale P

更新日期：2015-10-01 00:00:00

abstract：:This study was undertaken to determine the sequence of events in the microenvironment of the intestinal tract that culminate in the symptoms of cholera and to attempt to define more clearly the mechanisms involved in antibacterial immunity. The extent to which mucus occurs in the normal intestine of rabbits and the ap...

journal_title：Infection and immunity

authors： Schrank GD,Verwey WF

更新日期：1976-01-01 00:00:00

abstract：:We previously showed the requirement of both T cells and gamma interferon (IFN-gamma)-producing non-T cells for the genetic resistance of BALB/c mice to the development of toxoplasmic encephalitis (TE). In order to define the role of IFN-gamma production and the perforin-mediated cytotoxicity of T cells in this resist...

journal_title：Infection and immunity

authors： Wang X,Kang H,Kikuchi T,Suzuki Y

更新日期：2004-08-01 00:00:00

abstract：:Urinary tract infection (UTI) is the second most common infection in humans, making it a global health priority. Nearly half of all women will experience a symptomatic UTI, with uropathogenic Escherichia coli (UPEC) being the major causative agent of the infection. Although there has been extensive research on UPEC vi...

journal_title：Infection and immunity

authors： Sintsova A,Smith S,Subashchandrabose S,Mobley HL

更新日期：2018-02-20 00:00:00

abstract：:Mammalian hosts often develop distinct immune response against the diverse parasitic helminths that have evolved for immune evasion. Interleukin-25 (IL-25), an IL-17 cytokine family member, plays a key role in initiating the protective immunity against several parasitic helminths; however, the involvement and underlyi...

journal_title：Infection and immunity

authors： Angkasekwinai P,Srimanote P,Wang YH,Pootong A,Sakolvaree Y,Pattanapanyasat K,Chaicumpa W,Chaiyaroj S,Dong C

更新日期：2013-10-01 00:00:00