Abstract:
:Brefeldin A has been recently characterized to act as an inhibitor of intracellular protein export with profound effects on the structure and function of the Golgi apparatus in animal cells. Manifold activities of the antibiotic (under different names) published in the 1960's and 1970's are reviewed: effects on fungal growth and morphogenesis, inhibition of mitosis in plant cells, cytotoxicity, cancerostatic, antiviral and antinematodal activity and peculiar effects on DNA, RNA and protein synthesis in microbial and animal cells.
journal_name
Folia Microbiol (Praha)journal_title
Folia microbiologicaauthors
Betina Vdoi
10.1007/BF02814572keywords:
subject
Has Abstractpub_date
1992-01-01 00:00:00pages
3-11issue
1eissn
0015-5632issn
1874-9356journal_volume
37pub_type
杂志文章,评审abstract::Single chain Fv (scFv) antibodies (generated by phage display technology, molecules representing new and efficient tools in the research and diagnostics of infectious diseases) against the capsid protein (p25) of Maedi-Visna virus were selected. Several clones of p25 specific scFv antibodies were identified; one of th...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931380
更新日期:2003-01-01 00:00:00
abstract::One-week dextran sulfate treatment of conventional (CV) immunodeficient (SCID) mice gave rise to acute colitis in the colon mucosa; germ-free (GF) SCID mice did not exhibit any changes in colon morphology. Dextran sulfate application to CV immunocompetent (BALB/c) mice did induce substantial changes in the colon mucos...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02818004
更新日期:2001-01-01 00:00:00
abstract::Oxidizing and assimilating ability of the yeast Candida utilis 49 was tested with 21 different low-boiling organic compounds which come as components of raw synthetic ethanol. The highest yields of yeast dry weight were obtained with ethanol (72.0%), propanol (48.2%), ethyl acetate (43.4%) and acetic acid (34.2%). To ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02876965
更新日期:1976-01-01 00:00:00
abstract::Based on the ability to attach to polymeric surfaces, the formation of biofilms was determined in 5 wild-type strains (Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumanii, Escherichia coli, Staphylococcus warneri). Using modified Christensen method, minimum regrowth concentration (MRC) of piperacilli...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931650
更新日期:2004-01-01 00:00:00
abstract::In the original publication, the number of the NCTC strain used was published incorrectly. The authors apologize for the error. The error has no effect on the validity of the results and is corrected for accuracy. ...
journal_title:Folia microbiologica
pub_type: 杂志文章,已发布勘误
doi:10.1007/s12223-017-0558-z
更新日期:2018-01-01 00:00:00
abstract::Procedures to introduce point mutations, restriction sites and insert or delete DNA fragments are very important tools to study protein function. We describe here two-step PCR-based method for generating single or multiple mutations, insertions and deletions in a small region of the sequence. In the first step, a uniq...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02816213
更新日期:1999-01-01 00:00:00
abstract::Enterococcus faecalis is a ubiquitous bacterium of the gut that is observed in persistent periradicular infections. Its pathogenicity is associated with biofilm formation and the ability to survive under nutrient-poor (starvation) conditions. However, characteristics of chemical composition of biofilm cells developed ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-014-0319-1
更新日期:2014-09-01 00:00:00
abstract::Phytoplankton successions under ice cover (January-March) were determined in four oligotrophic lakes (Burtjärn, Aspen, Vialamptjärn and Storkorstjärn) located in North-Eastern Sweden. The total phosphorus concentration in the lakes was less than 10 micrograms/L. Lake Burtjärn (reference lake) had a similar hydrology a...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931370
更新日期:2003-01-01 00:00:00
abstract::Cryptosporidiosis belongs to the important parasitic infections with zoonotic potential and the occurrence in European countries is rare. The first cases of cryptosporidiosis caused by Cryptosporidium hominis detected in the Slovak republic were described here. Collection of examined humans consisted of five family me...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-012-0182-x
更新日期:2013-01-01 00:00:00
abstract::Moderately halophilic bacteria utilizing phenol as the sole carbon source were isolated by selective enrichment from sea water. The isolate (Gram-negative motile rods) was identified as Deleya venusta. It grew well in the presence of up to 1600 mg/L of phenol and 8% NaCl under aerobic conditions. When the cells were t...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02815617
更新日期:2001-01-01 00:00:00
abstract::Staphylococcus epidermidis is a biofilm-forming bacterial strain that can cause major problems as an agent of nosocomial infections. Bacteria in biofilms are shielded from the environment and can survive high doses of antibiotics. We here test the antibiotic susceptibility of Staphylococcus epidermidis to rising genta...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-017-0568-x
更新日期:2018-05-01 00:00:00
abstract::We have investigated the expression of cyclins, cyclin dependent kinases (CDK), and CDK inhibitors (CKI) at the mRNA level in a panel of small-cell lung cancer (SCLC) cell lines in vitro and in vivo as xenografts in nude mice. The results showed that the cell lines expressed varying amounts of most cyclin and CDK's bu...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02820804
更新日期:1998-01-01 00:00:00
abstract::The ability of Phanerochaete chrysosporium, Trametes versicolor, Coriolopsis polyzona, and Pleurotus ostreatus growing in a mitogen-limited mineral medium (NMM) to degrade PCBs in a commercial, Delor 106 mixture at a concentration of 0.9 ppm was compared. The respective amount of PCBs removed from the fungal cultures ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02898723
更新日期:1997-01-01 00:00:00
abstract::A decrease in the content of ochratoxin A (OA) was observed in milk samples fermented by yoghurt bacteria and bifidobacteria. OA was added to the milk before fermentation at a rate of 0.05-1.5 mg/L. No residues of OA were found in samples containing 0.05 and 0.1 mg/L of OA, fermented by S. Salivarius subsp. thermophil...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02816335
更新日期:1996-01-01 00:00:00
abstract::Adhesion of group B streptococci to human epithelial vaginal and buccal cells proceeded in three phases which differed qualitatively. Maximum adhesion took place within 10 min of interaction, during the second phase (10-15 min), the percentage of adherent cells decreased significantly (P less than 0.05) whereas during...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02884088
更新日期:1983-01-01 00:00:00
abstract::The vacA and cagA genotypes of Helicobacter pylori exhibited distinct geographic distribution and correlation with severity of disease. In the above genotypes (obtained from 150 H. pylori-positive patients--139 with gastritis, 10 with ulcer and 1 patient with gastric cancer) combinations vacA s1/m1 and s2/m2 were dete...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02932113
更新日期:2007-01-01 00:00:00
abstract::A soil streptomycete degraded hair, silk, wool, feather and leather which were collected from solid wastes. The organism was identified taxonomically and designated Streptomyces sp. A956. It degraded leather to the maximum extent and solubilized 35.9% of the total nitrogen, 2.32 mg of glycine equivalent amino nitrogen...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02927178
更新日期:1979-01-01 00:00:00
abstract::Secreted aspartyl proteinase (Sap) distribution among different C. albicans isolates was determined using SAP-specific primers in polymerase chain reaction (PCR) assay. SAP1, SAP2, and SAP3 were detected in 13 of 40 (32.5%), SAP4 in 38/40 (95%), SAP5 were detected in 30/40 (75%), SAP6 in 23/40 (57.5%) of C. albicans s...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931422
更新日期:2005-01-01 00:00:00
abstract::The purpose of this study was to isolate bioluminescent strains and to phenotypically and biochemically identify them based on the 16S rRNA gene sequence. 16S rRNA gene sequence analysis of the 11 isolates revealed that they belonged to Shewanella woodyi. Nevertheless, they were determined to exhibit various growth ch...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-013-0269-z
更新日期:2014-01-01 00:00:00
abstract::Treatment of human group C and G streptococci with cyanogen bromide results in solubilization of surface protein G molecules. Strain-to-strain variation in the quantity, molar mass and functional activity of protein G extracted from representative group C and G isolates led to the identification of three structurally ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02825666
更新日期:1999-01-01 00:00:00
abstract::Mutants of Streptomyces coeruleorubidus, blocked in the biosynthesis of anthracycline antibiotics of the daunomycine complex, were isolated from the production strains after treatment with UV light, gamma-radiation, nitrous acid, and after natural selection; according to their different biosynthetic activity the mutan...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02876678
更新日期:1978-01-01 00:00:00
abstract::As phospholipases of mycoplasma species may play a role in the pathogenesis of respiratory tract and urogenital tract diseases Mycoplasma mycoides and Acholeplasma laidlawii were examined as to the production of phospholipase A2 (PLA) and attempts were made to purify and characterize it. Both species produced PLA. The...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814471
更新日期:1989-01-01 00:00:00
abstract::Effect of oxygen and metabolic substrates (glucose, ethanol) on the catalase activity of anaerobically grown Schizosaccharomyces pombe cells was assessed and compared with that of Saccharomyces cerevisiae in order to determine the catalase activity regulation in S. pombe. In contrast to S. cerevisiae, the total catala...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02818575
更新日期:1998-01-01 00:00:00
abstract::Strains of genus Citrobacter (152 isolates from 1950 to 1988 deposited in the Czech National Collection of Type Cultures, Prague) were re-classified using biological and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) methods. One-hundred thirty-six strains (ca. 90 %) were i...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-014-0340-4
更新日期:2015-01-01 00:00:00
abstract::Using mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine, a number of homoserine auxotrophs have been isolated from a glutamate-producing Arthrobacter globiformis excreting L-lysine in good amounts. For further improvement, mutants resistant to the lysine analog S-(2-aminoethyl)-L-cysteine have been isolated from h...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02935823
更新日期:1991-01-01 00:00:00
abstract::In yeast, the STB5 gene encodes a transcriptional factor belonging to binuclear cluster class (Zn2Cys6) of transcriptional regulators specific to ascomycetes. In this study, we prepared the Kluyveromyces lactis stb5Δ strain and assessed its responses to different stresses. We showed that KlSTB5 gene is able to complem...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-019-00682-7
更新日期:2019-07-01 00:00:00
abstract::The resistance to killing by free radicals of two mutants ofPhaffia rhodozyma was determined. Mutant 5-7 did not produce astaxanthin but produced beta-carotene, while mutant 3-4 did not produce any carotenoid pigments. The resistance of mutant 5-7 was the same as that of the wild type but mutant 3-4 was rapidly killed...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02816505
更新日期:1998-01-01 00:00:00
abstract::Chemical and microscopic features of wood decay by the basidiomycete Coriolopsis occidentalis are described. The fungus was grown on blocks of poplar, oak, and fir wood and caused significant mass, lignin, and saccharide losses in all kinds of wood. Poplar wood was particularly strongly affected. Twelve weeks after in...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814527
更新日期:1994-01-01 00:00:00
abstract::Killer strains of Saccharomyces cerevisiae producing killer toxin K1 kill sensitive cells but are resistant to their own toxin. It is assumed that in the producer, an effective interaction between the external toxin and its plasma membrane receptor or the final effector is not possible on the grounds of a conformation...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02932122
更新日期:2006-01-01 00:00:00
abstract::We report a novel application of calcein-acetomethyl ester in flow cytometry for rapid estimation of the number of G+-bacteria in rodent feces (Apodemus sylvaticus and Mus sp.f. muridae). We also use the combined application of flow cytometry and Syto-13 or Sypro Orange staining to count rapidly the total bacterial po...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931538
更新日期:2004-01-01 00:00:00