Abstract:
:In yeast, the STB5 gene encodes a transcriptional factor belonging to binuclear cluster class (Zn2Cys6) of transcriptional regulators specific to ascomycetes. In this study, we prepared the Kluyveromyces lactis stb5Δ strain and assessed its responses to different stresses. We showed that KlSTB5 gene is able to complement the deficiencies of Saccharomyces cerevisiae stb5Δ mutant. The results of phenotypic analysis suggested that KlSTB5 gene deletion did not sensitize K. lactis cells to oxidative stress inducing compounds but led to Klstb5Δ resistance to 4-nitroquinoline-N-oxide and hygromycin B. Expression analysis indicated that the loss of KlSTB5 gene function induced the transcription of drug efflux pump encoding genes that might contribute to increased 4-nitroquinoline-N-oxide and hygromycin B tolerance. Our results show that KlStb5p functions as negative regulator of some ABC transporter genes in K. lactis.
journal_name
Folia Microbiol (Praha)journal_title
Folia microbiologicaauthors
Bencova A,Konecna A,Toth Hervay N,Gbelska Ydoi
10.1007/s12223-019-00682-7subject
Has Abstractpub_date
2019-07-01 00:00:00pages
579-586issue
4eissn
0015-5632issn
1874-9356pii
10.1007/s12223-019-00682-7journal_volume
64pub_type
杂志文章abstract::Phosphatidylcholine is one of the most frequent phospholipid components of the inner mitochondrial membrane of Neurospora crassa. Quantitative analysis of phosphlipids of the wild strain of Neurospora crassa and of its two cho mutants showed that these strains did not significantly differ in the content of phosphatidy...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02879763
更新日期:1982-01-01 00:00:00
abstract::In the present study, the cDNA sequences of Hsp70 and Hsp90 genes of Isaria farinosa (designated IFHSP70 and IFHSP90) were cloned and characterized using multiple techniques of molecular biology and bioinformatics. The genetic differentiation of the two genes was investigated among 10 geographically separated populati...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-018-00676-x
更新日期:2019-07-01 00:00:00
abstract::Raoultella spp. representatives are Gram-negative capsulated, nonmotile rods. These bacteria are found in the natural environment: plants, water, soil and insects. R. ornithinolytica is one of the three species of Raoultella. R. ornithinolytica is the only species within the genus which has the ability to produce orni...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-015-0390-2
更新日期:2015-11-01 00:00:00
abstract::In ostriches and pheasants, there is still limited information relating to staphylococci and their properties. Biogenic amines (BAs) are nitrogenous low-molecular-weight substances with biological functions in animals, plants and microorganisms. In this study, we focused on BA production by targeted faecal staphylococ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-017-0492-0
更新日期:2017-05-01 00:00:00
abstract::Almost all dried vegetative trichomes ofAnabaena iyengarii, Westiellopsis prolifica andNostochopsis lobatus died within 1 h, while those ofOscillatoria acuminata retained viability to some extent for 1 d under similar storage conditions. The viability of dried vegetative trichomes ofO. acuminata decreased about equall...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02903715
更新日期:1999-01-01 00:00:00
abstract::Killer strains of Saccharomyces cerevisiae producing killer toxin K1 kill sensitive cells but are resistant to their own toxin. It is assumed that in the producer, an effective interaction between the external toxin and its plasma membrane receptor or the final effector is not possible on the grounds of a conformation...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02932122
更新日期:2006-01-01 00:00:00
abstract::The ability of the rumen ciliates to utilize β-glucans other than cellulose and xylan is currently being recognized. The objective of the present study was to characterize the ability of the ciliate Diploplastron affine to digest some pachyman, laminarin, pustulan, curdlan and lichean. The protozoa were isolated from ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-012-0120-y
更新日期:2012-07-01 00:00:00
abstract::The antifungal effect of 2-alkylthio-6-amino- and 2-alkylthio-6-formamidobenzothiazoles (22 derivatives in all) on Aspergillus niger and various Candida yeasts was tested. No significant effect was observed with A. niger. With the pathogenic yeast species C. albicans and C. guilliermondii, the most efficient derivativ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814461
更新日期:1989-01-01 00:00:00
abstract::Biological activity of secondary metabolites produced by a plant-growth-promoting Pseudomonas fluorescens was evaluated. The strain produced antibiotics phenazine (PHE), 2,4-diacetylphloroglucinol (PHL) and siderophore pyoverdin (PYO) in standard King's B and succinic acid media, respectively. After extraction, PYO wa...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02818690
更新日期:2002-01-01 00:00:00
abstract::Using fermentation with a selected strain of Acetomonas oxydans it was possible to convert 2-deoxy-2-fluro-D-glucitol to 5-deoxy-5-fluoro-L-sorbose, in agreement with Bertrand's and Hudson's rule. The last-named compound was isolated in a yield of 88%. Both compounds were little toxic against Acetomonas oxydans. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02877659
更新日期:1977-01-01 00:00:00
abstract::Oxidizing and assimilating ability of the yeast Candida utilis 49 was tested with 21 different low-boiling organic compounds which come as components of raw synthetic ethanol. The highest yields of yeast dry weight were obtained with ethanol (72.0%), propanol (48.2%), ethyl acetate (43.4%) and acetic acid (34.2%). To ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02876965
更新日期:1976-01-01 00:00:00
abstract::Euglena ignobilis cells in natural puddle water of pH 7.8, when kept at 21 +/- 2 degrees C and under continuous light (intensity of approximately 30 micromol m(-2) s(-1)) in a culture chamber, decreased their speed of movement from > or = 78000 microm/min (after a 12-h cultivation), to 850-1300 microm/min after 18 h. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931412
更新日期:2005-01-01 00:00:00
abstract::Glutamate was converted to glutamine by Corynebacterium glutamicum permeabilized by ethanol (10%). ATP was supplied to the reaction by dried Saccharomyces cerevisiae or regenerated by acetyl kinase. High glutamine synthetase activity in C. glutamicum was induced by cultivation of the microorganism in media containing ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02816248
更新日期:1999-01-01 00:00:00
abstract::A decrease in the content of ochratoxin A (OA) was observed in milk samples fermented by yoghurt bacteria and bifidobacteria. OA was added to the milk before fermentation at a rate of 0.05-1.5 mg/L. No residues of OA were found in samples containing 0.05 and 0.1 mg/L of OA, fermented by S. Salivarius subsp. thermophil...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02816335
更新日期:1996-01-01 00:00:00
abstract::Staphylococcus aureus is a leading cause of bloodstream infections (BSI) and diseases that may be caused by hematogenous spread. The staphylococcal adhesin, for which the association with the infections emerging as a complication of septicemia has been well documented, is a bone sialoprotein-binding protein (Bbp). The...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-014-0321-7
更新日期:2014-11-01 00:00:00
abstract::As a part of a program to develop starter cultures aiding in the spoilage control and sanitation of African fermented foods, a cereal-based food ('ogi' and its solid form 'agidi' or 'eko') was prepared using a bacteriocin-producing Lactobacillus strain as the starter culture. The survival of an enterotoxigenic Escheri...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02898642
更新日期:1997-01-01 00:00:00
abstract::Murine herpesvirus 68 (MHV-68) is a natural pathogen that infects murid rodents, which serves as hosts for Ixodes ricinus ticks. For the first time, MHV-68 was detected in immature I. ricinus ticks feeding on Lacerta viridis lizards trapped in Slovakia, which supports the idea that ticks can acquire the virus from fee...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-018-0586-3
更新日期:2018-07-01 00:00:00
abstract::Fourteen of 200 Lactobacillus isolates from African fermented foods, viz. 'wara', 'kenkey', 'ugba', 'ogi', 'kunuzarki', 'fufu' and 'iru' were found to produce bacteriocins against L. plantarum and only three bacteriocinogenic isolates inhibited some of the food pathogens. Plasmid analysis of the 14 bacteriocin-produci...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814645
更新日期:1994-01-01 00:00:00
abstract::Some Bacillus subtilis mutants with different levels of homoserine dehydrogenase were described. Strains that do not accumulate methionine have a high homoserine dehydrogenase activity. Low activity was detected in mutants where cell growth was completely inhibited by 0.7 mmol/L methionine. A low concentration of dime...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02884064
更新日期:1991-01-01 00:00:00
abstract::It is proposed that the transcription of the c-2 repressor gene initiates at two promoters, pre and prm, similarly to the transcription of the c-I gene of lambda phage. In the P22 phage, these promoters are defined by mutations of c54 and K5. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02876780
更新日期:1975-01-01 00:00:00
abstract::For the first time, it was reported in France a cluster of autochthonous severe community-acquired (CA) infections due to the USA300 methicillin-resistant Staphylococcus aureus (MRSA) clone. The three cases belonged to the same family without any identified clue of abroad importation pathway. The domestic spread of US...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-014-0322-6
更新日期:2014-11-01 00:00:00
abstract::The emergence of spa types and spa-clonal complexes (CC) among clinical methicillin-resistant Staphylococcus aureus isolates collected from the University Clinical Center in Gdańsk between 2008 and 2009 were investigated. Phage typing was used as the initial screening in the study. The basic set of phages and the addi...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-012-0148-z
更新日期:2012-05-01 00:00:00
abstract::Bacteria accumulate high amounts of potassium in the cytoplasm. For studying transport of K+ (with 86Rb as a marker) in bacteria (Staphylococcus aureus 17810S), the cells were depleted of the internal K+ pool by a DNP treatment. Kinetics and energetics of 86Rb transport was assayed with glucose as an exogenous energy ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02816378
更新日期:1998-01-01 00:00:00
abstract::A case report of ventriculoperitoneal shunt infection caused by Candida lusitaniae in a 6-year-old patient with cerebral astrocytoma and obstructive hydrocephalus is presented briefly with emphasis on the course of antifungal treatment. Seven isolates recovered subsequently from the cerebrospinal fluid were studied re...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-011-0063-8
更新日期:2011-09-01 00:00:00
abstract::The green alga Scenedesmus intermedius was grown in synchronous culture under manganese or calcium deficiency for six successive generations. The growth rate, pigment and protein contents gradually decreased in comparison with the control. In Mn-deficient cells, the rate of oxygen evolution was sharply decreased. This...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02817561
更新日期:2000-01-01 00:00:00
abstract::Using mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine, a number of homoserine auxotrophs have been isolated from a glutamate-producing Arthrobacter globiformis excreting L-lysine in good amounts. For further improvement, mutants resistant to the lysine analog S-(2-aminoethyl)-L-cysteine have been isolated from h...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02935823
更新日期:1991-01-01 00:00:00
abstract::Twenty-one healthy bottle-fed infants were screened monthly (1-4 months) for bifidobacteria in their stools. Bifidobacteria were detected by culture and isolates specified by PCR. Alternatively, direct PCR in undiluted fecal suspensions was carried out for detection of bifidobacteria under the cultural detection level...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931594
更新日期:2006-01-01 00:00:00
abstract::The biosynthetic gene cluster of porothramycin, a sequence-selective DNA alkylating compound, was identified in the genome of producing strain Streptomyces albus subsp. albus (ATCC 39897) and sequentially characterized. A 39.7 kb long DNA region contains 27 putative genes, 18 of them revealing high similarity with hom...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-014-0339-x
更新日期:2014-11-01 00:00:00
abstract::The synergistic anticandidal activity of three diketopiperazines [cyclo-(L-Pro-L-Leu) (1), cyclo-(D-Pro-L-Leu) (2), and cyclo-(D-Pro-L-Tyr) (3)] purified from a Bacillus sp. N strain associated with entomopathogenic nematode Rhabditis (Oscheius) in combination with amphotericin B and clotrimazole was investigated usin...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-013-0234-x
更新日期:2013-11-01 00:00:00
abstract::The effect of subinhibitory concentrations (subMICs) of new organic ammonium salts of four homologous series of alkylammonium bromides (32 compounds) was determined with respect to the induction of lysogenic strain prophage, influence of permeability reactions in a rabbit skin test and cytotoxic changes of monolayers ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02815414
更新日期:1995-01-01 00:00:00