Relationship between the composition of phospholipids and respiratory activity of choline-deficient mutants of Neurospora crassa.

Abstract:

:Phosphatidylcholine is one of the most frequent phospholipid components of the inner mitochondrial membrane of Neurospora crassa. Quantitative analysis of phosphlipids of the wild strain of Neurospora crassa and of its two cho mutants showed that these strains did not significantly differ in the content of phosphatidylcholine. Mutants cultivated in a medium without choline contained, as compared with the wild strain, an increased amount of phosphatidylserine and a decreased quantity of phosphatidic acid. Respiratory activity increased and sensitivity to inhibitors of respiration changed. It is likely that the presence of choline in the growth medium exerts a regulatory effect on the cell metabolism of these mutants.

journal_title

Folia microbiologica

authors

Fecíková H,Gbelská Y,Baráth Z,Grmanová M

doi

10.1007/BF02879763

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

76-80

issue

2

eissn

0015-5632

issn

1874-9356

journal_volume

27

pub_type

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