Pharmacodynamic parameters of aminoglycosides and their effect on exoenzymes of Pseudomonas aeruginosa.

Abstract:

:Aminoglycosides at 2x or 4x minimum inhibitory concentration induced postantibiotic effects against Pseudomonas aeruginosa lasting 3.5-4.9 h (gentamicin) and 0.5-3.7 h (selemycin). Postantibiotic effects of subinhibitory concentrations of the aminoglycosides tested were substantially longer. Some combinations of supra- and subinhibitory concentrations of antibiotics did not even allow any regrowth of the bacterial strain. The postantibiotic effects and postantibiotic effects of subinhibitory concentrations of gentamicin and selemycin were associated with changes of P. aeruginosa elastase and proteinase. Combinations of supra- and subinhibitory concentrations more pronouncedly suppressed enzymic activities than did suprainhibitory concentrations alone.

journal_title

Folia microbiologica

authors

Hostacká A

doi

10.1007/BF02814691

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

149-53

issue

2

eissn

0015-5632

issn

1874-9356

journal_volume

41

pub_type

杂志文章
  • Membrane fluidity in Bacillus subtilis. Validity of homeoviscous adaptation.

    abstract::The validity of the principle of homeoviscous adaptation for Bacillus subtilis was tested by comparing fluorescence anisotropy (1,6-diphenyl-1,3,5-hexatriene) and electron-spin resonance (16-doxylstearate) measurements carried out in isolated plasma membranes and in phospholipid fractions. The physical measurements we...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02925901

    authors: Svobodová J,Julák J,Pilar J,Svoboda P

    更新日期:1988-01-01 00:00:00

  • Transcriptional regulators of seven yeast species: comparative genome analysis. Review.

    abstract::The regulation of gene transcription allows yeast cells to respond properly to changing environmental conditions. Several protein complexes take part in this process. They involve RNA polymerase complexes, chromatin remodeling complexes, mediators, general transcription factors and specific transcriptional regulators....

    journal_title:Folia microbiologica

    pub_type: 杂志文章,评审

    doi:10.1007/s12223-008-0044-8

    authors: Drobná E,Bialková A,Subík J

    更新日期:2008-01-01 00:00:00

  • Stb5p is involved in Kluyveromyces lactis response to 4-nitroquinoline-N-oxide stress.

    abstract::In yeast, the STB5 gene encodes a transcriptional factor belonging to binuclear cluster class (Zn2Cys6) of transcriptional regulators specific to ascomycetes. In this study, we prepared the Kluyveromyces lactis stb5Δ strain and assessed its responses to different stresses. We showed that KlSTB5 gene is able to complem...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-019-00682-7

    authors: Bencova A,Konecna A,Toth Hervay N,Gbelska Y

    更新日期:2019-07-01 00:00:00

  • Relationship between sporulation and synthesis of mycobacillin and dipicolinic acid under condition of catabolite repression in Bacillus subtilis.

    abstract::Sporulation was repressed in the parent strain by various carbon sources whereas glucose-resistant mutants were resistant to them but not to glycerol 2-phosphate. Both mycobacillin and dipicolinic acid synthesis were repressed in the parent by some of the compounds tested, viz. glucose, pyruvate and glycerol 2-phospha...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02928000

    authors: Majumdar S,Basu S,Das SK,Bose SK

    更新日期:1986-01-01 00:00:00

  • Detection of Coxiella burnetii DNA and anti-Coxiella burnetii IgG antibodies in precolostral blood samples of stillborn calves in an endemically infected Holstein dairy herd.

    abstract::Coxiella burnetii (C. burnetii), an intracellular zoonotic bacterium causing Q fever, occurs widely in cattle herds. After invasion of the pregnant uterus and initial localization in the placenta, active C. burnetii infections may spread to the fetus hematogenously or by the amniotic-oral route and thus may cause abor...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-017-0553-4

    authors: Freick M,Konrath A,Enbergs H,Walraph J,Weber J,Eulenberger K

    更新日期:2018-03-01 00:00:00

  • Ovine scrapie: priorities and importance.

    abstract::Ovine and caprine scrapie occupies a unique place among animal transmissive spongiform encephalopathies (TSE). It is an object of intensive biomedicinal, ecological and economical studies. Its causative agents are demonstrably associated with the development of TSE in farmed minks, goats and moufflons. Ovine strains o...

    journal_title:Folia microbiologica

    pub_type: 杂志文章,评审

    doi:10.1007/BF02818713

    authors: Novák M,Vrtiak OJ,Mikula I,Tkáciková L

    更新日期:2000-01-01 00:00:00

  • Analysis of genetic variations of heat shock proteins Hsp70 and Hsp90 in Isaria farinosa strains from the Yunnan province of China.

    abstract::In the present study, the cDNA sequences of Hsp70 and Hsp90 genes of Isaria farinosa (designated IFHSP70 and IFHSP90) were cloned and characterized using multiple techniques of molecular biology and bioinformatics. The genetic differentiation of the two genes was investigated among 10 geographically separated populati...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-018-00676-x

    authors: He L,Yu H,Dai Y,Wang Y

    更新日期:2019-07-01 00:00:00

  • Recombinant single-chain Fv antibodies that recognize the p25 protein of the Maedi-Visna virus.

    abstract::Single chain Fv (scFv) antibodies (generated by phage display technology, molecules representing new and efficient tools in the research and diagnostics of infectious diseases) against the capsid protein (p25) of Maedi-Visna virus were selected. Several clones of p25 specific scFv antibodies were identified; one of th...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02931380

    authors: Celer V,Blazek D,Navrátilová I,Skládal P,Blacklaws B,Bujdoso R

    更新日期:2003-01-01 00:00:00

  • Intracellular colonization of Rhododendron and Vaccinium roots by Cenococcum geophilum, Geomyces pannorum and Meliniomyces variabilis.

    abstract::Four in vitro experiments were set up to verify the colonization potential of ectomycorrhizal (EcM) Cenococcum geophilum FR. (strain CGE-4), saprotrophic Geomyces pannorum (LINK) SIGLER & CARMICHAEL (GPA-1) and a frequent root-associated, potentially ericoid mycorrhiza (ErM)-forming Meliniomyces variabilis Hambleton &...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02932096

    authors: Vohník M,Fendrych M,Albrechtová J,Vosátka M

    更新日期:2007-01-01 00:00:00

  • Activity of the AIB factor observed in prokaryotic and eukaryotic microorganisms.

    abstract::Streptomyces cinnamonensis produces a new substance named AIB (for anti-isobutyrate) factor which, on a solid medium, efficiently counteracts toxic concentrations not only of isobutyrate but also of other salts of short-chain monocarboxylic acids. In the present study we demonstrate that the AIB factor activity is wid...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02891697

    authors: Pospísil S,Vánová M,Machurová V

    更新日期:1993-01-01 00:00:00

  • Pullulanase: model protein substrate for the general secretory pathway of gram-negative bacteria.

    abstract::Pullulanase of Klebsiella oxytoca is one of a wide variety of extracellular proteins that are secreted by Gram-negative bacteria by the complex main terminal branch (MTB) of the general secretory pathway. The roles of some of the 14 components of the MTB are now becoming clear. In this review it is proposed that most ...

    journal_title:Folia microbiologica

    pub_type: 杂志文章,评审

    doi:10.1007/BF02818976

    authors: Pugsley AP,Francetic O,Hardie K,Possot OM,Sauvonnet N,Seydel A

    更新日期:1997-01-01 00:00:00

  • Transformation in Bacillus subtilis. Initial stages of the transformation process and their energy dependence.

    abstract::NaN3 was found to inhibit transformation but not the irreversible binding of donor 3H-DNA in competent cells of the original low-transformable strain Bacillus subtilis 168 trp2. Addition of NaN3 to cells of two mutants Bacillus subtilis HT39 and HT46 with an increased transformability decreased substantially the irrev...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02877669

    authors: Tichý P,Jandová Z

    更新日期:1977-01-01 00:00:00

  • First detection of murine herpesvirus 68 in adult Ixodes ricinus ticks.

    abstract::Murine herpesvirus 68 (MHV-68) is a natural pathogen that infects murid rodents, which serves as hosts for Ixodes ricinus ticks. For the first time, MHV-68 was detected in immature I. ricinus ticks feeding on Lacerta viridis lizards trapped in Slovakia, which supports the idea that ticks can acquire the virus from fee...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-018-0586-3

    authors: Kúdelová M,Jánošová M,Belvončíková P

    更新日期:2018-07-01 00:00:00

  • Inhibition of yeast-mycelium transformation by 2-alkylthio-6-amino- and 2-alkylthio-6-formamidobenzothiazoles and their in vitro antifungal activity.

    abstract::The antifungal effect of 2-alkylthio-6-amino- and 2-alkylthio-6-formamidobenzothiazoles (22 derivatives in all) on Aspergillus niger and various Candida yeasts was tested. No significant effect was observed with A. niger. With the pathogenic yeast species C. albicans and C. guilliermondii, the most efficient derivativ...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02814461

    authors: Kuchta T,Bujdáková H,Sidóová E

    更新日期:1989-01-01 00:00:00

  • Comparison of antimicrobial efficacy of a fixed dose combination of ceftazidime + sulbactam with ceftazidime and sulbactam alone against five bacteria.

    abstract::The efficacy of the agents was evaluated on the basis of minimum inhibitory concentration (MIC) and time-kill curve analysis in Pseudomonas aeruginosa, Staphylococcus aureus, Acinetobacter baumannii, Mycobacterium smegmatis, and Citrobacter braakii; MIC was found to be 0.5, 4.0, 0.015625, 0.0078125, and 0.0625 mg/L in...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-009-0054-1

    authors: Shrivastava SM,Shukla SK,Chaudhary M

    更新日期:2009-09-01 00:00:00

  • Amino acid control mechanism for bacitracin formation by Bacillus licheniformis.

    abstract::Several amino acids affected the amount of bacitracin produced by Bacillus licheniformis ATCC 10716 and the high-yielding mutant B. licheniformis AL. The possibility of an amino acid control mechanism for bacitracin biosynthesis is discussed. The two strains showed a different response to the addition of some amino ac...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02926454

    authors: Haavik HI

    更新日期:1979-01-01 00:00:00

  • First autochthonous familial cluster of invasive community-acquired leukocidin-positive methicillin-resistant USA300 Staphylococcus aureus in France.

    abstract::For the first time, it was reported in France a cluster of autochthonous severe community-acquired (CA) infections due to the USA300 methicillin-resistant Staphylococcus aureus (MRSA) clone. The three cases belonged to the same family without any identified clue of abroad importation pathway. The domestic spread of US...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-014-0322-6

    authors: Traore P,Bourgeois-Nicolaos N,Ruimy R,Laurent F,Labrune P,Doucet-Populaire F,Decousser JW

    更新日期:2014-11-01 00:00:00

  • Effects of oxidative stress on the production of carotenoid pigments byPhaffia rhodozyma (Xanthophyllomyces dendrorhous).

    abstract::The resistance to killing by free radicals of two mutants ofPhaffia rhodozyma was determined. Mutant 5-7 did not produce astaxanthin but produced beta-carotene, while mutant 3-4 did not produce any carotenoid pigments. The resistance of mutant 5-7 was the same as that of the wild type but mutant 3-4 was rapidly killed...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02816505

    authors: Santopietro LM,Spencer JF,Spencer DM,Siñeriz F

    更新日期:1998-01-01 00:00:00

  • DNA synthesis in Escherichia coli B/r after UV-irradiation.

    abstract::When studying the kinetics of DNA synthesis, growth and cell division in Escherichia coli B/r after irradiation with different doses of UV-radiation (254 nm) we could demonstrate, by means of pulse incorporation of 3H-thymidine, a lag in DNA synthesis after the irradiation. The relative rate of the restored DNA synthe...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02876446

    authors: Kucerová H,Vĕchet B

    更新日期:1982-01-01 00:00:00

  • First report of Candida bracarensis in Mexico: hydrolytic enzymes and antifungal susceptibility pattern.

    abstract::Candida bracarensis is an emerging cryptic species within the Candida glabrata clade. To date, little is known about its epidemiology, virulence, and antifungal susceptibility. This study documents the occurrence of C. bracarensis for the first time in Mexico and focuses on its in vitro production of hydrolytic enzyme...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-018-0592-5

    authors: Treviño-Rangel RJ,Espinosa-Pérez JF,Villanueva-Lozano H,Montoya AM,Andrade A,Bonifaz A,González GM

    更新日期:2018-07-01 00:00:00

  • Regulation of the activity of intracellular alanylaminopeptidase synthesized by Pseudomonas sp.

    abstract::Activity of purified alanylaminopeptidase of Pseudomonas sp. measured in the presence of the alanine derivative of 2-naphthoic acid (NA-Ala) is inhibited by 1,10-phenanthroline, EDTA, bestatin and amastatin; this finding supports the conclusion that this enzyme is a metallo-aminopeptidase. A decrease of its activity i...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02817643

    authors: Jankiewicz U,Bielawski W

    更新日期:2002-01-01 00:00:00

  • Molecular diversity analysis of Rhizoctonia solani isolates infecting various pulse crops in different agro-ecological regions of India.

    abstract::Genetic diversity of 89 isolates of Rhizoctonia solani isolated from different pulse crops representing 21 states from 16 agro-ecological regions of India, 49 morphological, and 7 anastomosis groups (AGs) was analyzed using 12 universal rice primers (URPs), 22 random amplified polymorphic DNA (RAPD), and 23 inter-simp...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-012-0165-y

    authors: Dubey SC,Tripathi A,Upadhyay BK

    更新日期:2012-11-01 00:00:00

  • Extrusion of metabolites from baker's yeast during glucose-induced acidification.

    abstract::Extrusion of metabolites (glycerol, lactic, malic, and succinic acid) during the medium acidification caused by resting baker's yeast supplied with 200 mM glucose was studied under aerobic and anaerobic conditions and in the absence and presence of 14 mM KCl. The maximum levels of glycerol and of the sum of acids (abo...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02876611

    authors: Sigler K,Knotková A,Páca J,Wurst M

    更新日期:1980-01-01 00:00:00

  • Increased oxidative stress tolerance results in general stress tolerance in Candida albicans independently of stress-elicited morphological transitions.

    abstract::A selection of tert-butylhydroperoxide (tBOOH)-tolerant Candida albicans mutants showed increased tolerances to 19 different stress conditions. These mutants are characterized by a constitutively upregulated antioxidative defense system and, therefore, adaptation to oxidative stress may play an important role in gaini...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-014-0305-7

    authors: Jakab Á,Antal K,Kiss Á,Emri T,Pócsi I

    更新日期:2014-07-01 00:00:00

  • Analysis of ICAM1 gene polymorphism in Slovak multiple sclerosis patients.

    abstract::Infiltration of immune cells into CNS is one of the essential events in multiple sclerosis (MS) development. Adhesion molecules like the intercellular adhesion molecule 1 (ICAM-1) play critical role in this process. Therefore, the ICAM1 gene containing two important single-nucleotide polymorphisms (SNPs) belongs to ca...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-017-0499-6

    authors: Shawkatová I,Javor J,Párnická Z,Bucová M,Čopíková-Cudráková D,Michalík J,Gmitterová K,Čierny D,Buc M,Ďurmanová V

    更新日期:2017-07-01 00:00:00

  • Pullulan production by Aureobasidium pullulans cells immobilized in chitosan beads. Fungal pullulan production by immobilized cells.

    abstract::Fungal cells of Aureobasidium pullulans ATCC 201253 were immobilized by entrapment in chitosan beads, and the immobilized cells were investigated for their ability to produce the polysaccharide pullulan using batch fermentation. The 1% chitosan-entrapped fungal cells were capable of producing pullulan for two cycles o...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/s12223-011-0048-7

    authors: West TP

    更新日期:2011-07-01 00:00:00

  • Plasmid profiles of bacteriocin-producing Lactobacillus isolates from African fermented foods.

    abstract::Fourteen of 200 Lactobacillus isolates from African fermented foods, viz. 'wara', 'kenkey', 'ugba', 'ogi', 'kunuzarki', 'fufu' and 'iru' were found to produce bacteriocins against L. plantarum and only three bacteriocinogenic isolates inhibited some of the food pathogens. Plasmid analysis of the 14 bacteriocin-produci...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02814645

    authors: Olasupo NA,Olukoya DK,Odunfa SA

    更新日期:1994-01-01 00:00:00

  • Expression of cell cycle regulating factor mRNA in small cell lung cancer xenografts.

    abstract::We have investigated the expression of cyclins, cyclin dependent kinases (CDK), and CDK inhibitors (CKI) at the mRNA level in a panel of small-cell lung cancer (SCLC) cell lines in vitro and in vivo as xenografts in nude mice. The results showed that the cell lines expressed varying amounts of most cyclin and CDK's bu...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02820804

    authors: Krarup M,Poulsen HS,Spang-Thomsen M

    更新日期:1998-01-01 00:00:00

  • Biological effects of the antibiotic brefeldin A (decumbin, cyanein, ascotoxin, synergisidin): a retrospective.

    abstract::Brefeldin A has been recently characterized to act as an inhibitor of intracellular protein export with profound effects on the structure and function of the Golgi apparatus in animal cells. Manifold activities of the antibiotic (under different names) published in the 1960's and 1970's are reviewed: effects on fungal...

    journal_title:Folia microbiologica

    pub_type: 杂志文章,评审

    doi:10.1007/BF02814572

    authors: Betina V

    更新日期:1992-01-01 00:00:00

  • Kinetics of soluble glucan production by Claviceps viridis.

    abstract::Among 18 tested strains of Claviceps spp., 7 produced significant amounts of exocellular polysaccharide (EPS). The maximum production of EPS was found in fermentation broth of Claviceps viridis. The kinetics of growth, substrate consumption, and EPS production in the batch, aerobic, submerged culture of this fungus we...

    journal_title:Folia microbiologica

    pub_type: 杂志文章

    doi:10.1007/BF02993470

    authors: Flieger M,Kantorová M,Benesová T,Pazoutová S,Votruba J

    更新日期:2003-01-01 00:00:00