First report of Candida bracarensis in Mexico: hydrolytic enzymes and antifungal susceptibility pattern.

Abstract:

:Candida bracarensis is an emerging cryptic species within the Candida glabrata clade. To date, little is known about its epidemiology, virulence, and antifungal susceptibility. This study documents the occurrence of C. bracarensis for the first time in Mexico and focuses on its in vitro production of hydrolytic enzymes, as well as antifungal susceptibility to echinocandins. This strain was isolated from a vaginal swab of a female with vulvovaginal candidosis; exhibited a very strong activity of aspartyl proteinase, phospholipase, and hemolysin; and was susceptible to caspofungin, anidulafungin, and micafungin (MIC = 0.031 μg/mL). Data obtained could contribute to the knowledge of the epidemiology and virulence attributes of this yeast as a fungal opportunistic human pathogen.

journal_title

Folia microbiologica

authors

Treviño-Rangel RJ,Espinosa-Pérez JF,Villanueva-Lozano H,Montoya AM,Andrade A,Bonifaz A,González GM

doi

10.1007/s12223-018-0592-5

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

517-523

issue

4

eissn

0015-5632

issn

1874-9356

pii

10.1007/s12223-018-0592-5

journal_volume

63

pub_type

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