Abstract:
:Ovine and caprine scrapie occupies a unique place among animal transmissive spongiform encephalopathies (TSE). It is an object of intensive biomedicinal, ecological and economical studies. Its causative agents are demonstrably associated with the development of TSE in farmed minks, goats and moufflons. Ovine strains of scrapie occurring in North America (particularly in the USA) differ from strains which occur in Europe and were present at the onset of development of TSE in three species of deer living in free nature and in captivity in the USA. The studies dealing with the development of bovine spongiform encephalopathy (BSE) of the English type have indicated justifiably that its origin is associated with one (or more) heretofore unidentified ovine strain. The development of a variant form, the Creutzfeldt-Jacob disease in humans, and transmission of the BSE agent to several families of bovidae, felidae and primates, puts stress on its zoonotic potential. All this leads to the conclusion that domesticated sheep are the decisive reservoir species of animal TSE. They have been infected to an unknown extent with the causative agent of BSE probably through contaminated meat-bone meal. The occurrence of natural ovine prion isolates with properties similar to those of the BSE agent requires that scrapie should be included in the surveillance of human and animal TSE. At present, scrapie is a noticeable disease also in other than European Communities Member States. It is on the list B of the International Epizootics Office. Many countries have initiated control of ovine scrapie. It should therefore become a topical question also in Central and Eastern European countries. Elimination or even eradication of ovine scrapie (or its causative agents) from populations of small and large domestic ruminants is the prerequisite for prevention of penetration of ovine pathogenic prions into the human feed chain. Moreover, it should be ensured that these species will be able to produce foods of a new type (immunotrition and similar) or proteins with therapeutic effects in the near future. Our study established that the PrP genotype of Valachian rams, the Slovak autochthonous breed, contains also VRQ and ARQ alleles encoding the susceptibility to scrapie. Their selection is part of the improvement of Slovak Valachian sheep towards resistance to scrapie.
journal_name
Folia Microbiol (Praha)journal_title
Folia microbiologicaauthors
Novák M,Vrtiak OJ,Mikula I,Tkáciková Ldoi
10.1007/BF02818713keywords:
subject
Has Abstractpub_date
2000-01-01 00:00:00pages
475-83issue
6eissn
0015-5632issn
1874-9356journal_volume
45pub_type
杂志文章,评审abstract::Altered cell signaling is the molecular basis for cell proliferation occurring in association with several gamma herpesvirus infections. Three gamma herpesviruses, namely EBV/HHV-4, KSHV/HHV-8 and the MHV-68 (and/or MHV-72) and their unusual cell-pirated gene products are discussed in this respect. The EBV, KSHV as we...
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02931360
更新日期:2003-01-01 00:00:00
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journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814620
更新日期:1996-01-01 00:00:00
abstract::We have investigated the expression of cyclins, cyclin dependent kinases (CDK), and CDK inhibitors (CKI) at the mRNA level in a panel of small-cell lung cancer (SCLC) cell lines in vitro and in vivo as xenografts in nude mice. The results showed that the cell lines expressed varying amounts of most cyclin and CDK's bu...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02820804
更新日期:1998-01-01 00:00:00
abstract::The synergistic anticandidal activity of three diketopiperazines [cyclo-(L-Pro-L-Leu) (1), cyclo-(D-Pro-L-Leu) (2), and cyclo-(D-Pro-L-Tyr) (3)] purified from a Bacillus sp. N strain associated with entomopathogenic nematode Rhabditis (Oscheius) in combination with amphotericin B and clotrimazole was investigated usin...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-013-0234-x
更新日期:2013-11-01 00:00:00
abstract::Almost all dried vegetative trichomes ofAnabaena iyengarii, Westiellopsis prolifica andNostochopsis lobatus died within 1 h, while those ofOscillatoria acuminata retained viability to some extent for 1 d under similar storage conditions. The viability of dried vegetative trichomes ofO. acuminata decreased about equall...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02903715
更新日期:1999-01-01 00:00:00
abstract::NaN3 was found to inhibit transformation but not the irreversible binding of donor 3H-DNA in competent cells of the original low-transformable strain Bacillus subtilis 168 trp2. Addition of NaN3 to cells of two mutants Bacillus subtilis HT39 and HT46 with an increased transformability decreased substantially the irrev...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02877669
更新日期:1977-01-01 00:00:00
abstract::The ability of the rumen ciliates to utilize β-glucans other than cellulose and xylan is currently being recognized. The objective of the present study was to characterize the ability of the ciliate Diploplastron affine to digest some pachyman, laminarin, pustulan, curdlan and lichean. The protozoa were isolated from ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-012-0120-y
更新日期:2012-07-01 00:00:00
abstract::Blastoschizomyces capitatus is an uncommon, opportunistic pathogenic fungus, which causes invasive and disseminated infections. This microorganism is normally present in both environmental and normal human flora. Within a host, B. capitatus is able to grow in both unicellular yeast and multicellular filamentous growth...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-013-0273-3
更新日期:2014-03-01 00:00:00
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journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931412
更新日期:2005-01-01 00:00:00
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journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814471
更新日期:1989-01-01 00:00:00
abstract::The newly described type strains Arcanobacterium pinnipediorum DSM 28752T and Arcanobacterium wilhelmae DSM 102162T, initially isolated from an anal swab of a harbor seal (Sammra et al. Int J Syst Evol Microbiol 65:4539-4543, 2015) and the genital tract of a rhinoceros (Sammra et al. Int J Syst Evol Microbiol 67:2093-...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-018-0610-7
更新日期:2018-11-01 00:00:00
abstract::The soil microbial population, determined over a period of 19 months and the elemental chemical composition measured by X-ray fluorescence techniques were followed in two uncultivated salt-affected areas of Greece, namely Lantza and Klidi. The ecological conditions at Lantza remained stable during the period of study ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02877387
更新日期:1983-01-01 00:00:00
abstract::Inhibition activity of the alkaloid (-)-corypalmine on spore germination of plant pathogenic and saprophytic fungi (Alternaria solani, A brassicicola, A. brassicae, A. melongenae, Curvularia pallescens, C. lunata, C. maculans, Curvularisa sp., Colletotrichum sp., Helminthosporium speciferum, H. frumentacei, H. pennise...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02817654
更新日期:2002-01-01 00:00:00
abstract::Infiltration of immune cells into CNS is one of the essential events in multiple sclerosis (MS) development. Adhesion molecules like the intercellular adhesion molecule 1 (ICAM-1) play critical role in this process. Therefore, the ICAM1 gene containing two important single-nucleotide polymorphisms (SNPs) belongs to ca...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-017-0499-6
更新日期:2017-07-01 00:00:00
abstract::The majority of antibiotics and substances with diverse biological activity used in medicine are produced by actinomycetes, nonfilamentous bacteria and fungi. Other microorganisms, such as myxobacteria, pseudomonads, nocardias, basidiomycetes, marine microorganisms, enterobacteria, halobacteria, hyperthermophiles etc....
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02993460
更新日期:2003-01-01 00:00:00
abstract::Effects of increasing doses of UV-B radiation on photosynthetic efficiency (PE) and motility in Chlamydomonas reinhardtii were investigated. The exposure time ranged from 10 to 120 min at 0.73 W/m2 UV-B radiation. A decrease in compensation points (CP) was followed by an increase in PE on extending the UV-B treatment ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02817448
更新日期:2000-01-01 00:00:00
abstract::Using phenol--water extraction, a lipopeptidopolysaccharide complex (LPPS) was isolated from Listeria monocytogenes. Some biological and immunological properties of LPPS were compared with lipopolysaccharide isolated by the same procedure from Salmonella typhimurium. LPPS possesses low pyrogenicity, but the immunologi...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02923515
更新日期:1985-01-01 00:00:00
abstract::Ten thermophilic Gram-positive bacteria were isolated from various soils of Saudi Arabia. The strains are spore-forming rods belonging to the species Bacillus stearothermophilus. The cells are motile, strictly aerobic, catalase and oxidase positive. The sporangia appear to be swollen and their position varies from ter...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02927328
更新日期:1981-01-01 00:00:00
abstract::The regulation of gene transcription allows yeast cells to respond properly to changing environmental conditions. Several protein complexes take part in this process. They involve RNA polymerase complexes, chromatin remodeling complexes, mediators, general transcription factors and specific transcriptional regulators....
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/s12223-008-0044-8
更新日期:2008-01-01 00:00:00
abstract::Treatment of human group C and G streptococci with cyanogen bromide results in solubilization of surface protein G molecules. Strain-to-strain variation in the quantity, molar mass and functional activity of protein G extracted from representative group C and G isolates led to the identification of three structurally ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02825666
更新日期:1999-01-01 00:00:00
abstract::Cultures of 33 basidiomycete strains out of 35 tested were viable with unchanged characteristics after four years of maintenance on perlite in cryovials. These cultures can be a good substitute for agar cultures in long-term maintenance of fungi. For comparison, the storage under oil was evaluated but it turned out to...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-008-0084-0
更新日期:2008-01-01 00:00:00
abstract::Overpopulation of domestic pigeons is considered to be one of the major problems of urban centers, as these birds are responsible for the dissemination of relevant pathogens to animal and human health. The aim of this study was to detect potentially pathogenic Escherichia coli and Salmonella spp. in domestic pigeons c...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-020-00781-w
更新日期:2020-08-01 00:00:00
abstract::Killer strains of Saccharomyces cerevisiae producing killer toxin K1 kill sensitive cells but are resistant to their own toxin. It is assumed that in the producer, an effective interaction between the external toxin and its plasma membrane receptor or the final effector is not possible on the grounds of a conformation...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02932122
更新日期:2006-01-01 00:00:00
abstract::The effect of paraquat on the activities of antioxidant defense and detoxifying enzymes of the white-rot fungus Funalia trogii was determined. Paraquat increased the activities of glutathione reductase (GR), glutathione transferase (GT) and superoxide dismutase at 1 mmol/L, while at 0.1 mmol/L it did not affect the ac...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02818700
更新日期:2002-01-01 00:00:00
abstract::We present the results of analysis of membrane phosphoproteomes from individual morphological stages of Streptomyces coelicolor that reflect developmentally dependent heterogeneity and phosphorylation of intrinsic and externally added purified Strepomyces aureofaciens EF-Tu. Fast growing nonpathogenic Mycobacterium sm...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-010-0029-2
更新日期:2010-05-01 00:00:00
abstract::Investigation of the dependence of cell yield of Candida boidinii in a chemostat and specific growth rate in a turbidostat on temperature was carried out using methanol as substrate. Each of the curves obtained had only one maximum, the optimum temperature for yield (Ys) and for specific growth rate (micron) being som...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02885600
更新日期:1977-01-01 00:00:00
abstract::A total of 152 lactic acid bacteria (LAB) were isolated from pickles produced in the Ankara-Çubuk region. These isolates were clustered into eight groups on the basis of their phenotypic characteristics including cell morphology, CO2 production from glucose, growth at 10 and 45 °C, growth in 6.5 % NaCl, and growth at ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-014-0363-x
更新日期:2015-05-01 00:00:00
abstract::Three types of heterogeneous preparations and four types of preparations of polysaccharide nature were obtained in studies aimed at the isolation of active compounds from Aspergillus flavus conidia bearing their biological stimulatory activity. Extraction with trichloroacetic acid at 0 degrees C yielded a preparation ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02927425
更新日期:1981-01-01 00:00:00
abstract::For the first time, it was reported in France a cluster of autochthonous severe community-acquired (CA) infections due to the USA300 methicillin-resistant Staphylococcus aureus (MRSA) clone. The three cases belonged to the same family without any identified clue of abroad importation pathway. The domestic spread of US...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-014-0322-6
更新日期:2014-11-01 00:00:00
abstract::A small-colony forming variant of Escherichia coli with a mutation in the ncf gene was analysed. The alternation of the protein composition in the cytoplasmic membrane and the interaction with K and E group colicins indicated a membrane mutation. The effect of this mutation on some membrane-bound processes, the activi...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02885601
更新日期:1977-01-01 00:00:00