Phenol-water extracts of gram-positive Listeria monocytogenes and gram-negative Salmonella typhimurium. Comparison of biological activities.

Abstract:

:Using phenol--water extraction, a lipopeptidopolysaccharide complex (LPPS) was isolated from Listeria monocytogenes. Some biological and immunological properties of LPPS were compared with lipopolysaccharide isolated by the same procedure from Salmonella typhimurium. LPPS possesses low pyrogenicity, but the immunological activity is comparable with LPS: slightly lower adjuvant and polyclonal stimulating effect, almost equal mitogenic effect on mouse spleen cells and higher mitogenic effect on human peripheral blood cells. The results are discussed in connection with the chemical structure of both substances.

journal_title

Folia microbiologica

authors

Hofman J,Pospísil M,Mára M,Hríbalová V

doi

10.1007/BF02923515

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

231-6

issue

3

eissn

0015-5632

issn

1874-9356

journal_volume

30

pub_type

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