Abstract:
:One-week dextran sulfate treatment of conventional (CV) immunodeficient (SCID) mice gave rise to acute colitis in the colon mucosa; germ-free (GF) SCID mice did not exhibit any changes in colon morphology. Dextran sulfate application to CV immunocompetent (BALB/c) mice did induce substantial changes in the colon mucosa (grade 4); GF BALB/c mice showed mild changes in the colon morphology (grade 1) only. GF SCID mice and CV SCID mice died during the second round of dextran sulfate treatment suffering from chronic colitis; GF BALB/c mice exhibited mild crypt distortion while CV BALB/c mice showed a complete loss of the surface epithelium (grade 4), accompanied by T and B lymphocyte infiltration.
journal_name
Folia Microbiol (Praha)journal_title
Folia microbiologicaauthors
Hudcovic T,Stĕpánková R,Cebra J,Tlaskalová-Hogenová Hdoi
10.1007/BF02818004keywords:
subject
Has Abstractpub_date
2001-01-01 00:00:00pages
565-72issue
6eissn
0015-5632issn
1874-9356journal_volume
46pub_type
杂志文章abstract::Using fermentation with a selected strain of Acetomonas oxydans it was possible to convert 2-deoxy-2-fluro-D-glucitol to 5-deoxy-5-fluoro-L-sorbose, in agreement with Bertrand's and Hudson's rule. The last-named compound was isolated in a yield of 88%. Both compounds were little toxic against Acetomonas oxydans. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02877659
更新日期:1977-01-01 00:00:00
abstract::Mice (strains Balb/c and A/J) received an intravenous infusion of bilirubin for a 1 d period. The infusion was delivered at various phases of the primary reaction; the degree of the immune response was expressed as the number of antibody-forming cells against sheep erythrocytes. Bilirubin infusion during both the indu...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02897214
更新日期:1980-01-01 00:00:00
abstract::The biological activity and the presence of genes sfp and ituD (surfactin and iturin A) among Bacillus strains isolated from the Amazon basin were determined. Bacillus spp. were tested for hemolytic activity and inhibition of fungal growth by agar plate assays in parallel with PCR for identification of sfp and ituD ge...
journal_title:Folia microbiologica
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doi:10.1007/s12223-011-0056-7
更新日期:2011-07-01 00:00:00
abstract::This work was aimed to develop a multiplex PCR assay to detect infectious agents such as Clavibacter michiganensis subsp. michiganensis, Fusarium sp, Leveillula taurica, and begomoviruses in tomato (Solanum lycopersicum) plants. Specific primer sets of each pathogen were designed based on intergenic ribosomal RNA sequ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-012-0206-6
更新日期:2013-07-01 00:00:00
abstract::The effect of paraquat on the activities of antioxidant defense and detoxifying enzymes of the white-rot fungus Funalia trogii was determined. Paraquat increased the activities of glutathione reductase (GR), glutathione transferase (GT) and superoxide dismutase at 1 mmol/L, while at 0.1 mmol/L it did not affect the ac...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02818700
更新日期:2002-01-01 00:00:00
abstract::Distribution of microtubules and F-actin in aerobically growing cells of Dipodascus magnusii, belonging to the class Saccharomycetes was analyzed using immunofluorescence microscopy and labeling with rhodamine-tagged phalloidin. A conspicuous system of permanent cytoplasmic microtubules was observed in association wit...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02930952
更新日期:2003-01-01 00:00:00
abstract::Gut microbiome lives in the intestinal tract of animals and plays an important role in almost all life processes. Gut microbiome balance is beneficial to health, and imbalance leads to many diseases, one of which is obesity epidemic. However, gut microbiome is also influenced by host hormone, and different gut microbi...
journal_title:Folia microbiologica
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更新日期:2019-11-01 00:00:00
abstract::The gene corresponding to the recently identified whiB-paralogous gene wblE in S. coelicolor was found after sequencing the downstream region of the stress-response sporulation-specific sigma-factor gene, sigH, in S. coelicolor A3(2). Sequence analysis has revealed an ORF exhibiting high similarity to sporulation tran...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931330
更新日期:2003-01-01 00:00:00
abstract::The production of bacterial enzymes in batch fermentations is compared with results obtained in continuous culture. When studying the production of alpha-amylase in Bacillus subtilis it was found that instability of the enzyme synthesis was due to nonhomogeneity of the population rather than to "the culture's history"...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02883137
更新日期:1982-01-01 00:00:00
abstract::Genome projects produce a huge amount of sequence information. As a result, the focus of genomics research is turning toward deduction of functional information about newly discovered genes. Thus structural genomics paves the way for a new discipline called functional genomics by providing the information required for...
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02931546
更新日期:2004-01-01 00:00:00
abstract::Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) exerts multiple effects on viral and host cellular activities during infection, including induction of the cell cycle G2 arrest, and cell death in both human cells and the fission yeast Schizosaccharomyces pombe. We show that treament of exponential-pha...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931584
更新日期:2006-01-01 00:00:00
abstract::Lactobacillus bulgaricus 59 and L. casei RTS and their respective nitrosoguanidine-induced mutants were estimated for titratable and volatile acidities, production of biacetyl and acetoin and for proteolytic activity. Both the mutants showed a marked increase in proteolytic activity as compared to the parents. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02897216
更新日期:1980-01-01 00:00:00
abstract::Strains of fungi imperfecti of genera Aspergillus and Rhizopus were tested for the ability to produce alpha-mannosidases. The most suitable alpha-mannosidase producer of a total of 20 strains under study was Aspergillus Ravus Link 69. The parameters studied during the cultivation included the growth rate expressed as ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02876433
更新日期:1978-01-01 00:00:00
abstract::The regulation of gene transcription allows yeast cells to respond properly to changing environmental conditions. Several protein complexes take part in this process. They involve RNA polymerase complexes, chromatin remodeling complexes, mediators, general transcription factors and specific transcriptional regulators....
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/s12223-008-0044-8
更新日期:2008-01-01 00:00:00
abstract::Virus-like particles (VLPs) were isolated from the yeast Wickerhamia fluorescens strain CCY61-1-1. The VLPs are approximately 42 nm in diameter and contain only one species of dsRNA molecule. The apparent length of the dsRNA determined by native agarose gel electrophoresis was 4.6 kbp. Analysis of protein content of t...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814620
更新日期:1996-01-01 00:00:00
abstract::Levels of phenotypic and genotypic diversity among seven Megasphaera elsdenii strains recovered from rumen contents of cattle, sheep and lambs were determined by a combination of antibiotic-resistance analysis and PCR fingerprint techniques targeted both to the ribosomal RNA operon (ARDRA, RISA) and the whole genome (...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931818
更新日期:2006-01-01 00:00:00
abstract::Pullulanase of Klebsiella oxytoca is one of a wide variety of extracellular proteins that are secreted by Gram-negative bacteria by the complex main terminal branch (MTB) of the general secretory pathway. The roles of some of the 14 components of the MTB are now becoming clear. In this review it is proposed that most ...
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02818976
更新日期:1997-01-01 00:00:00
abstract::The efficacy of the agents was evaluated on the basis of minimum inhibitory concentration (MIC) and time-kill curve analysis in Pseudomonas aeruginosa, Staphylococcus aureus, Acinetobacter baumannii, Mycobacterium smegmatis, and Citrobacter braakii; MIC was found to be 0.5, 4.0, 0.015625, 0.0078125, and 0.0625 mg/L in...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/s12223-009-0054-1
更新日期:2009-09-01 00:00:00
abstract::The addition of a nitrogen (nitrate) and carbon sources (acetate, citrate and fructose) and phosphate deficiency (nitrate medium deficient in phosphate) under unaerated conditions induced akinete differentiation in Anabaena torulosa. Aerated cultures of this organism in these nutrients did not differentiate akinetes. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02817617
更新日期:2000-01-01 00:00:00
abstract::Composition of sterol fractions of nystatin-resistant Candida maltosa strains was determined. Using UV-spectrometry, TLC and GLC-MS it was demonstrated that resistance to nystatin is connected with the composition alterations of yeast cell sterols. Block of different stages of ergosterol biosynthesis was revealed in s...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814494
更新日期:1991-01-01 00:00:00
abstract::When studying the kinetics of DNA synthesis, growth and cell division in Escherichia coli B/r after irradiation with different doses of UV-radiation (254 nm) we could demonstrate, by means of pulse incorporation of 3H-thymidine, a lag in DNA synthesis after the irradiation. The relative rate of the restored DNA synthe...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02876446
更新日期:1982-01-01 00:00:00
abstract::Using an in vitro cytotoxicity assay (51Cr-release), it was shown that bilirubin exerts a cytotoxic effect on both adult and newborn human lymphocytes after a 1-d incubation of cells with bilirubin. The effect of bilirubin on human granulocytes was less pronounced; the association of the cytotoxic effect with a functi...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02923520
更新日期:1985-01-01 00:00:00
abstract::A naturally deficient thiamine and methionine requiring strain of Bacillus coagulans (Ms 5) accumulates lysine in medium only when exogenous pyridoxine (optimal concentration, 0.1 mu g/ml) are supplied. Threonine exerts an inhibitory effect at higher concentrations but pyridoxine does not. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02877085
更新日期:1975-01-01 00:00:00
abstract::The properties of the 37400 oncogenic strain of Agrobacterium tumefaciens are described. This strain was derived from the VI lysogenic strain originally isolated by Hamilton from a Zinnia elegans tumour. Strain 37400 has a number of properties which render it suitable for quantitative and genetic studies. It is cured ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02876963
更新日期:1976-01-01 00:00:00
abstract::Single chain Fv (scFv) antibodies (generated by phage display technology, molecules representing new and efficient tools in the research and diagnostics of infectious diseases) against the capsid protein (p25) of Maedi-Visna virus were selected. Several clones of p25 specific scFv antibodies were identified; one of th...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931380
更新日期:2003-01-01 00:00:00
abstract::Contemporary aspects of cerebrospinal fluid analysis are discussed, including the relationship to neuro-infective, autoimmune and other neurological diseases. The actual state of cerebrospinal fluid microbiological and cytological investigation and analysis of cerebrospinal fluid protein fractions are described in det...
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02931522
更新日期:2003-01-01 00:00:00
abstract::Dithiocarbamates were found to enhance the production of citric acid under solid-state fermentation conditions by Aspergillus niger. Maximum increase was observed with tetramethylthiuram disulfide (TMTD). Percent increases observed were 74.2% with 2.5 micrograms/mL of TMTD, 19.6% with 2.5 micrograms/mL of sodium dimet...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02926953
更新日期:1986-01-01 00:00:00
abstract::The effect of immersion time and cell concentration in the attachment of several lactic acid bacteria with antibacterial activity to beef-muscle surface was studied. The number of firmly attached bacteria increased with immersion time in the case of Pediococcus acidilacti, Lactobacillus sake, Lactococcus cremoris (two...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814710
更新日期:1996-01-01 00:00:00
abstract::Euglena ignobilis cells in natural puddle water of pH 7.8, when kept at 21 +/- 2 degrees C and under continuous light (intensity of approximately 30 micromol m(-2) s(-1)) in a culture chamber, decreased their speed of movement from > or = 78000 microm/min (after a 12-h cultivation), to 850-1300 microm/min after 18 h. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02931412
更新日期:2005-01-01 00:00:00
abstract::A new strain of Bacillus sp. was isolated from a hot water spring in India. This strain generated a high activity of extracellular beta-galactosidase at 37 degrees C in shake flasks. The beta-galactosidase activity was found to increase continuously but the production rate was slower than with some other organisms rep...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02903706
更新日期:1999-01-01 00:00:00