Linkage between toxin production and purine biosynthesis in Clostridium difficile.

abstract：:Streptococcus oralis has emerged as one of the most important organisms of the viridans streptococcus group in terms of infections and is recognised as an agent of infective endocarditis and, in immunocompromised patients, septicaemia. The mechanisms by which this organism proliferates in vivo are unknown. However, ho...

journal_title：Journal of medical microbiology

authors： Byers HL,Homer KA,Tarelli E,Beighton D

更新日期：1999-04-01 00:00:00

abstract：:One hundred and twenty consecutive isolates of Neisseria gonorrhoeae from the County of Avon, UK, were examined by auxotyping and penicillin susceptibility testing. Requirements for proline (Pro), arginine (Arg), hypoxanthine (Hyp), uracil (Ura) and methionine (Met) were determined with a modified Heckels' medium. Pro...

journal_title：Journal of medical microbiology

authors： Copley CG,Egglestone SI

更新日期：1983-08-01 00:00:00

abstract：:To study the influence of normal associated microbiota on systemic immunological responses during experimental Chagas' disease, germ-free and conventional NIH Swiss mice were infected with Y strain of Trypanosoma cruzi. Although no statistical differences in mortality and parasitaemia were found, conventional mice sho...

journal_title：Journal of medical microbiology

authors： Duarte R,Silva AM,Vieira LQ,Afonso LCC,Nicoli JR

更新日期：2004-08-01 00:00:00

abstract：:Clostridium perfringens type A produces an enterotoxin that induces diarrhoea experimentally in man and animals. The enterotoxin causes increased membrane permeability in susceptible cells which is thought to be due to pore formation in the host cell membrane. The effect of purified C. perfringens enterotoxin on intac...

journal_title：Journal of medical microbiology

authors： Hardy SP,Denmead M,Parekh N,Granum PE

更新日期：1999-03-01 00:00:00

abstract：:Campylobacter fetus subsp. fetus infection can occur in female sheep, causing infertility or abortion. Despite extensive research on the effect of these bacteria on female fertility, little research has been done on the influence of C. fetus subsp. fetus on the male factor. Our objective was to examine the influence o...

journal_title：Journal of medical microbiology

authors： Zan Bar T,Yehuda R,Hacham T,Krupnik S,Bartoov B

更新日期：2008-11-01 00:00:00

abstract：:Encapsulation of purified tuberculoproteins in liposomes augmented their ability to elicit delayed hypersensitivity reactions in BCG-immune rats. The effect was most marked with a low-molecular-weight tuberculopeptide that was relatively poor at eliciting reactions when in free form. These findings indicate that, in a...

journal_title：Journal of medical microbiology

authors： Pimm MV,Baldwin RW

更新日期：1984-12-01 00:00:00

abstract：:The growth inhibiting activity of transferrins, citrate, 2-2' dipyridyl and desferrioxamine methanesulphonate towards Legionella spp. and their serogroups was investigated. The inhibitory activity of all these compounds depended upon the iron-free state of the molecules and was abolished by saturation with iron. No ba...

journal_title：Journal of medical microbiology

authors： Goldoni P,Visca P,Pastoris MC,Valenti P,Orsi N

更新日期：1991-02-01 00:00:00

abstract：:Bacteroides gracilis is a gram-negative anaerobic bacillus which requires formate and fumarate for growth; it has been implicated in periodontal disease and serious infections of the head and neck. In this study, Bacteroides ureolyticus (NTU) medium was tested for its ability to allow the growth of B. gracilis and oth...

journal_title：Journal of medical microbiology

authors： Wade WG,Bishop PA,Slayne MA

更新日期：1991-11-01 00:00:00

abstract：:Since its discovery at the end of the nineteenth century, Moraxella (Branhamella) catarrhalis has undergone several changes of nomenclature and periodic changes in its perceived status as either a commensal or a pathogen. Molecular analysis based on DNA hybridisation or 16S rDNA sequence comparisons has established it...

journal_title：Journal of medical microbiology

authors： Enright MC,McKenzie H

更新日期：1997-05-01 00:00:00

abstract：:This study was undertaken to investigate the synergistic interaction between amphotericin B (AmB) and acteoside, isolated from the aerial parts of the shrub Colebrookea oppositifolia (Lamiaceae). Acteoside alone exhibited no intrinsic antifungal activity but showed a potent synergism in combination with AmB against se...

journal_title：Journal of medical microbiology

authors： Ali I,Sharma P,Suri KA,Satti NK,Dutt P,Afrin F,Khan IA

更新日期：2011-09-01 00:00:00

abstract：:In this study, 90 non-replicate imipenem-resistant Pseudomonas aeruginosa (IRPA) Malaysian isolates collected between October 2005 and March 2008 were subjected to a screening test for detection of the integron and the gene cassette. Class 1 integrons were detected in 54 IRPA clinical isolates, whilst three isolates c...

journal_title：Journal of medical microbiology

authors： Khosravi Y,Tay ST,Vadivelu J

更新日期：2011-07-01 00:00:00

abstract：:Escherichia coli (2), Vibrio cholerae (2) and Aeromonas sobria (1) strains were examined for their ability to grow and produce toxins in samples of ileostomy fluid. Three categories of response were observed: no detectable growth, growth without detectable toxin, and growth with detectable toxin. Clear differences wer...

journal_title：Journal of medical microbiology

authors： Ala Aldeen DA,Barer MR

更新日期：1989-04-01 00:00:00

abstract：:A severe case of reptile-associated salmonellosis which caused septicaemia and meningitis in a 2-month-old baby is reported. The infrequent serotype Salmonella enterica subsp.(I) enterica serotype Abony (4,5 : b : enx) was detected in the human sample as well as in the pet turtle's faeces. The importance of regulation...

journal_title：Journal of medical microbiology

authors： Van Meervenne E,Botteldoorn N,Lokietek S,Vatlet M,Cupa A,Naranjo M,Dierick K,Bertrand S

更新日期：2009-10-01 00:00:00

abstract：:Breakthrough contamination of tuberculosis (TB) cultures is a problem in that it allows the overgrowth of another bacterium present in the sputum specimen, which can potentially mask the presence of Mycobacterium tuberculosis. The aim of this study was to isolate and characterize the bacterial organisms responsible fo...

journal_title：Journal of medical microbiology

authors： McClean M,Stanley T,Stanley S,Maeda Y,Goldsmith CE,Shepherd R,Millar BC,Dooley JS,Moore JE

更新日期：2011-09-01 00:00:00

abstract：:Vibrio vulnificus causes severe sepsis in humans. There are several reports about the relationship between host immunity and bacterial growth in V. vulnificus infection. However, the effect on leukocytes of V. vulnificus infection in vivo has not been elucidated. A murine model of V. vulnificus infection was used to i...

journal_title：Journal of medical microbiology

authors： Kashimoto T,Ueno S,Hayashi H,Hanajima M,Yoshioka K,Yoshida K,Mutoh K,Susa N

更新日期：2005-01-01 00:00:00

abstract：:A total of 817 human clinical isolates of Clostridium difficile from all Australian states were screened for A(-)B(+) strains by toxin gene PCR assays. Nine (1.1 %) strains were confirmed to be A(-)B(+) by enzyme immunoassay for toxin production. Of these, six (66.7 %) were binary toxin-positive by PCR. Using PCR ribo...

journal_title：Journal of medical microbiology

authors： Elliott B,Squire MM,Thean S,Chang BJ,Brazier JS,Rupnik M,Riley TV

更新日期：2011-08-01 00:00:00

abstract：:Acinetobacter junii is a rare human pathogen associated with bacteraemia in neonates and paediatric oncology patients. We present a case of A. junii causing bacteraemia in an adult transplant patient with leukaemia. The correct identification of Acinetobacter species can highlight the clinical significance of the diff...

journal_title：Journal of medical microbiology

authors： Cayô R,Yañez San Segundo L,Pérez Del Molino Bernal IC,García de la Fuente C,Bermúdez Rodríguez MA,Calvo J,Martínez-Martínez L

更新日期：2011-03-01 00:00:00

abstract：:Infection of humans by Abiotrophia defectiva, a nutritionally variant streptococcus, most commonly takes the form of endocarditis, though a variety of other manifestations ranging from central nervous system abscesses to orthopaedic infections have been seen. We report here what we believe is the first case of bullous...

journal_title：Journal of medical microbiology

authors： Anderson HM,Miller C,Kemp E,Huntington MK

更新日期：2012-07-01 00:00:00

abstract：:Rhodococcus equi is one of the most important causes of pneumonia in foals and has emerged as a significant opportunistic pathogen of immunosuppressed hosts such as human immunodeficiency virus-infected patients. Virulent R. equi harbouring an 85 kb plasmid, but not the avirulent form lacking the plasmid, has the abil...

journal_title：Journal of medical microbiology

authors： Toyooka K,Takai S,Kirikae T

更新日期：2005-11-01 00:00:00

abstract：:Growth of Candida albicans biofilms and production of extracellular matrix were monitored by dry weight, colorimetric and radioisotope assays, and by scanning electron microscopy. Under static incubation conditions synthesis of matrix material was minimal, but increased dramatically when developing biofilms were subje...

journal_title：Journal of medical microbiology

authors： Hawser SP,Baillie GS,Douglas LJ

更新日期：1998-03-01 00:00:00

abstract：PURPOSE:Non-host-adapted Salmonella serovars, including the common human food-borne pathogen Salmonella enterica serovar Typhimurium (S. Typhimurium), are opportunistic pathogens that can colonize food-producing animals without causing overt disease. Interventions against Salmonella are needed to enhance food safety, p...

journal_title：Journal of medical microbiology

authors： Bearson BL,Bearson SMD,Brunelle BW,Bayles DO,Lee IS,Kich JD

更新日期：2017-05-01 00:00:00

abstract：:In order to develop novel host/pathogen real-time PCR assays for routine diagnostic use, early gene expression patterns from both Epstein-Barr virus (EBV) and Raji cells were examined after inducing the lytic life cycle using 12-O-tetradecanoyl-13-phorbol ester and sodium butyrate. Real-time PCR identified several hig...

journal_title：Journal of medical microbiology

authors： Auburn H,Zuckerman M,Smith M

更新日期：2016-11-01 00:00:00

abstract：:Mycobacterium bovis is a pathogen of cattle. The unpasteurized milk of affected cattle is a source of infection in humans. Despite the screening of cattle and the pasteurization of milk, M bovis has not been eradicated. A high index of clinical suspicion is needed in symptomatic patients with a history of possible exp...

journal_title：Journal of medical microbiology

authors： Bilal S,Iqbal M,Murphy P,Power J

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:We examined evidence for transmission of Pandorea apista among cystic fibrosis (CF) patients attending paediatric and adult services in one city who had previously been found to harbour related isolates by pulsed-field gel electrophoresis (PFGE). METHODOLOGY:The whole-genome sequences of 18 isolates from this ...

journal_title：Journal of medical microbiology

authors： Kenna DTD,Coward A,Perry C,Pike R,Schaefer U,Turton J,Green H,Jones AM,Bright-Thomas RJ,Burns P,Narayan O,Wilkinson S,Turton JF

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:The aim of this work was to evaluate and optimize the identification of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica (usually known as the classical Bordetella species) using Bruker Biotyper matrix-assisted laser desorption ionization/time-of-flight mass spectrometry (MALDI-TOF M...

journal_title：Journal of medical microbiology

authors： Zintgraff J,Irazu L,Lara CS,Rodriguez M,Santos M

更新日期：2018-12-01 00:00:00

abstract：:Microcirculation plays a crucial role in mucosal physiological function as well as repair of gastric mucosal damage. Endothelial cell damage is known to disturb microcirculation and suppress angiogenesis. Therefore, the direct effect of Helicobacter pylori on endothelial cells in vitro was investigated with H. pylori ...

journal_title：Journal of medical microbiology

authors： Kurosawa A,Miwa H,Hirose M,Tsune I,Nagahara A,Sato N

更新日期：2002-05-01 00:00:00

abstract：:It is believed that most microbial infections are caused by pathogens organized in biofilms. Recently, it was shown that the dimorphic fungus Histoplasma capsulatum, estimated to be the most common cause of fungal respiratory diseases, is also able to form biofilm. Although the antifungal therapy commonly used is effe...

journal_title：Journal of medical microbiology

authors： Brilhante RSN,de Lima RAC,Marques FJF,Silva NF,Caetano ÉP,Castelo-Branco DSCM,Bandeira TJPG,Moreira JLB,Cordeiro RA,Monteiro AJ,Camargo ZP,Sidrim JJC,Rocha MFG

更新日期：2015-04-01 00:00:00

abstract：:Diagnosis of human immunodeficiency virus (HIV) infection by antibody-based testing allows for some recently infected individuals to be falsely assessed as non-infected. Since such individuals often have high viral loads and are capable of transmitting HIV, it is an imperative public health need to identify these indi...

journal_title：Journal of medical microbiology

authors： Ren A,Louie B,Rauch L,Castro L,Liska S,Klausner JD,Pandori MW

更新日期：2008-10-01 00:00:00

abstract：:Whole-cell-polypeptide profiles obtained by SDS-polyacrylamide gel electrophoresis (SDS-PAGE) were used in conjunction with the API-Staph technique to identify different strains of Staphylococcus aureus, S. epidermidis, S. saprophyticus and S. capitis. Complete concordance of results from both techniques was achieved ...

journal_title：Journal of medical microbiology

authors： Clink J,Pennington TH

更新日期：1987-02-01 00:00:00

abstract：:The purpose of this review is to discuss the scientific literature on waterborne healthcare-associated infections (HCAIs) published from 1990 to 2012. The review focuses on aquatic bacteria and describes both outbreaks and single cases in relation to patient characteristics, the settings and contaminated sources. An o...

journal_title：Journal of medical microbiology

authors： Ferranti G,Marchesi I,Favale M,Borella P,Bargellini A

更新日期：2014-10-01 00:00:00