Abstract：
:A total of 817 human clinical isolates of Clostridium difficile from all Australian states were screened for A(-)B(+) strains by toxin gene PCR assays. Nine (1.1 %) strains were confirmed to be A(-)B(+) by enzyme immunoassay for toxin production. Of these, six (66.7 %) were binary toxin-positive by PCR. Using PCR ribotyping and toxinotyping, the A(-)B(+) strains could be grouped into seven ribotypes and three toxinotypes. Only one of the ribotypes had been reported previously (017). The prevalence of ribotype 017 was low in this study with only two strains detected. Two new A(-)B(+) toxinotypes were also defined (XXX, XXXI). Toxinotype XXX had a toxin B gene similar to that of toxinotype IV (A(+)B(+)) but with a novel cytopathic region. Toxinotype XXXI was similar to other A(-)B(+) types (X, XVII), but had a larger deletion to the toxin A gene than in either of those types. The types of A(-)B(+) strains identified in this study differed markedly from those described in other regions.
journal_name
J Med Microbioljournal_title
Journal of medical microbiologyauthors
Elliott B,Squire MM,Thean S,Chang BJ,Brazier JS,Rupnik M,Riley TVdoi
10.1099/jmm.0.031062-0subject
Has Abstractpub_date
2011-08-01 00:00:00pages
1108-1111issue
Pt 8eissn
0022-2615issn
1473-5644journal_volume
60pub_type
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journal_title：Journal of medical microbiology
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journal_title：Journal of medical microbiology
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journal_title：Journal of medical microbiology
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更新日期：2001-01-01 00:00:00
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journal_title：Journal of medical microbiology
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更新日期：1978-05-01 00:00:00
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journal_title：Journal of medical microbiology
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journal_title：Journal of medical microbiology
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doi：10.1099/jmm.0.001183
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journal_title：Journal of medical microbiology
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更新日期：2006-07-01 00:00:00
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journal_title：Journal of medical microbiology
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doi：10.1099/0022-1317-49-2-187
更新日期：2000-02-01 00:00:00
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journal_title：Journal of medical microbiology
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更新日期：2019-06-01 00:00:00
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journal_title：Journal of medical microbiology
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doi：10.1099/jmm.0.47352-0
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journal_title：Journal of medical microbiology
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journal_title：Journal of medical microbiology
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更新日期：2001-04-01 00:00:00
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更新日期：2013-05-01 00:00:00
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journal_title：Journal of medical microbiology
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journal_title：Journal of medical microbiology
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更新日期：1981-02-01 00:00:00
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更新日期：1994-04-01 00:00:00
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journal_title：Journal of medical microbiology
pub_type： 杂志文章
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更新日期：1995-03-01 00:00:00
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journal_title：Journal of medical microbiology
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